Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors
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ClinicalTrials.gov Identifier: NCT03141021 |
Recruitment Status :
Recruiting
First Posted : May 4, 2017
Last Update Posted : November 21, 2023
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Condition or disease |
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Malignant Peripheral Nerve Sheath Tumors |
Study Type : | Observational [Patient Registry] |
Estimated Enrollment : | 1050 participants |
Observational Model: | Cohort |
Time Perspective: | Other |
Target Follow-Up Duration: | 10 Years |
Official Title: | Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors |
Actual Study Start Date : | April 28, 2017 |
Estimated Primary Completion Date : | April 30, 2053 |
Estimated Study Completion Date : | April 30, 2053 |
- Histologic characteristics of malignant peripheral nerve sheath tumor (MPNST) [ Time Frame: 10 years ]-The data collected through this registry will be used to analyze previously unanticipated patterns and prognostic clues about MPNST
- Immunohistochemical characteristics of malignant peripheral nerve sheath tumor (MPNST) [ Time Frame: 10 years ]-The data collected through this registry will be used to analyze previously unanticipated patterns and prognostic clues about MPNST
- Molecular characteristics of malignant peripheral nerve sheath tumor (MPNST) [ Time Frame: 10 years ]-The data collected through this registry will be used to analyze previously unanticipated patterns and prognostic clues about MPNST
- Radiographic characteristics of malignant peripheral nerve sheath tumor (MPNST) [ Time Frame: 10 years ]-The data collected through this registry will be used to analyze previously unanticipated patterns and prognostic clues about MPNST
- Treatment given to patients with malignant peripheral nerve sheath tumor (MPNST) [ Time Frame: 10 years ]-The data collected through this registry will be used to analyze previously unanticipated patterns and prognostic clues about MPNST
- Future genomic characterization of malignant peripheral nerve sheath tumor (MPNST) [ Time Frame: 10 years ]-The data collected through this registry will be used to analyze previously unanticipated patterns and prognostic clues about MPNST
Biospecimen Retention: Samples With DNA
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Ages Eligible for Study: | Child, Adult, Older Adult |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria and Exclusion Criteria:
-Any patient diagnosed with an MPNST is eligible for enrollment to this registry provided s/he consents to participate (or consent form his/her parent or legal guardian is obtained).
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03141021
Contact: Angela Hirbe, M.D., Ph.D. | (314) 362-8965 | hirbea@wustl.edu |
United States, Florida | |
Moffitt Cancer Center | Completed |
Tampa, Florida, United States, 33612 | |
United States, Maryland | |
Johns Hopkins | Recruiting |
Baltimore, Maryland, United States, 21205 | |
Contact: Christine Pratilas, M.D. 410-955-8751 | |
Principal Investigator: Christine Pratilas, M.D. | |
National Institutes of Health (NIH) | Not yet recruiting |
Bethesda, Maryland, United States, 20892 | |
Contact: Jack F Shern, M.D. 301-402-1444 john.shern@nih.gov | |
Principal Investigator: Jack F Shern, M.D. | |
United States, Massachusetts | |
Dana Farber Cancer Institute | Recruiting |
Boston, Massachusetts, United States, 02215 | |
Contact: David Miller, M.D., Ph.D. 617-355-8221 | |
Principal Investigator: David Miller, M.D., Ph.D. | |
United States, Minnesota | |
University of Minnesota | Withdrawn |
Minneapolis, Minnesota, United States, 55455 | |
United States, Missouri | |
Washington University School of Medicine | Recruiting |
Saint Louis, Missouri, United States, 63110 | |
Contact: Angela Hirbe, M.D., Ph.D. 314-362-8965 hirbea@wustl.edu | |
Principal Investigator: Angela Hirbe, M.D., Ph.D. | |
Sub-Investigator: David Gutmann, M.D., Ph.D. | |
Sub-Investigator: Sonika Dahiya, M.D., MBBS | |
Sub-Investigator: Brian Van Tine, M.D., Ph.D. | |
Sub-Investigator: Peter Oppelt, M.D. | |
United States, New York | |
Memorial Sloan Kettering Cancer Center | Not yet recruiting |
New York, New York, United States, 10065 | |
Contact: Ping Chi, M.D., Ph.D. 646-888-4166 | |
Principal Investigator: Ping Chi, M.D., Ph.D. | |
United States, Rhode Island | |
Lifespan | Completed |
Providence, Rhode Island, United States, 02903 | |
United States, Utah | |
University of Utah | Completed |
Salt Lake City, Utah, United States, 84112 | |
Canada, Ontario | |
Mount Sinai | Recruiting |
Toronto, Ontario, Canada, M5T 3L9 | |
Contact: Jay Wunder, M.D. 416-586-5995 jay.wunder@sinaihealthsystem.ca | |
Principal Investigator: Jay Wunder, M.D. | |
India | |
Global Gene Corporation | Recruiting |
Mumbai, India | |
Contact: Neeta Sarkar Roy, Ph.D. | |
Principal Investigator: Neeta Sarkar Roy, Ph.D. | |
United Kingdom | |
Royal National Orthopedic Hospital | Recruiting |
London, United Kingdom | |
Contact: Joanne McDonald | |
Principal Investigator: Joanne McDonald |
Principal Investigator: | Angela Hirbe, M.D., Ph.D. | Washington University School of Medicine |
Responsible Party: | Washington University School of Medicine |
ClinicalTrials.gov Identifier: | NCT03141021 |
Other Study ID Numbers: |
201702006 |
First Posted: | May 4, 2017 Key Record Dates |
Last Update Posted: | November 21, 2023 |
Last Verified: | November 2023 |
Individual Participant Data (IPD) Sharing Statement: | |
Plan to Share IPD: | No |
Studies a U.S. FDA-regulated Drug Product: | No |
Studies a U.S. FDA-regulated Device Product: | No |
Nerve Sheath Neoplasms Neurofibrosarcoma Neoplasms, Nerve Tissue Neoplasms by Histologic Type Neoplasms Peripheral Nervous System Neoplasms Nervous System Neoplasms Nervous System Diseases |
Peripheral Nervous System Diseases Neuromuscular Diseases Fibrosarcoma Neoplasms, Fibrous Tissue Neoplasms, Connective Tissue Neoplasms, Connective and Soft Tissue Sarcoma Neurofibroma |