Knee Osteoarthritis, Aging and Metabolic Syndrome
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ClinicalTrials.gov Identifier: NCT05955573 |
Recruitment Status :
Recruiting
First Posted : July 21, 2023
Last Update Posted : March 19, 2024
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Condition or disease | Intervention/treatment |
---|---|
Knee Osteoarthritis | Diagnostic Test: xray |
- Place of the study: Sohag university hospital.
- Type of study: Cross-Sectional Observational study
- Study period: Six months to one year The study will include Patients who met the American College of Rheumatology (ACR) clinical criteria for knee OA .
The following details will be obtained:
-
Demographic data : Age ,Sex ,Marital status ,Occupation ,Residence ,Education level
,Anthropometrical measures which included waist circumference (WC) and blood pressure (BP) will be obtained,History of chronic diseases (eg; Diabetes mellites, Hypertension)
- Clinical information: Symptom and its Duration. Plain radiographs of at least one knee [anteroposterior (A/P), lateral} will be taken.
- Laboratory findings included fasting blood sugar, serum levels of triglycerides, High-density lipoprotein cholesterol and total cholesterol.
Study Type : | Observational [Patient Registry] |
Estimated Enrollment : | 50 participants |
Observational Model: | Case-Only |
Time Perspective: | Cross-Sectional |
Target Follow-Up Duration: | 1 Month |
Official Title: | What Affects the Severity of Knee Osteoarthritis? Aging or Associated Metabolic Syndrome |
Actual Study Start Date : | August 20, 2023 |
Estimated Primary Completion Date : | June 2024 |
Estimated Study Completion Date : | August 2024 |
Group/Cohort | Intervention/treatment |
---|---|
knee osteoarthritis
Knee osteoarthritis
|
Diagnostic Test: xray
radiological description |
- severity of knee osteoarthritis [ Time Frame: 8/2023-8/2024 ]Kellgren and Lawrence (K/L) grading system of Knee osteoarthritis. It assigned a grade from 0 to 4, which they correlated to increasing severity of OA, with Grade 0 signifying no presence of OA and Grade 4 signifying severe OA .
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Ages Eligible for Study: | 30 Years and older (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Probability Sample |
Inclusion Criteria:
- Patients who met the American College of Rheumatology (ACR) clinical criteria for knee OA and had symptomatic OA of at least 1 knee (index knee), with a Kellgren / Lawrence (K/L) score ≥ 1 in that knee
Exclusion Criteria:
-
Any patient with a history of trauma to the knee
- Any other form of arthritis (e.g., rheumatoid arthritis, seronegative spondyloarthropathies, gout, pyrophosphate disease, or other crystal arthropathy)
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT05955573
Contact: Amany Mohamed abdelrahman, master | 01066706352 | amanymohamed@med.sohag.edu.eg | |
Contact: Hanan Sayed Abo-zaid, MD | 01150532194 |
Egypt | |
Sohag Faculty of Medicine | Recruiting |
Sohag, Egypt |
Study Chair: | Dalia Shaker Elgendy, MD | Sohag University | |
Study Director: | Hanan Sayed Abo-zaid, MD | Sohag University |
Publications:
Responsible Party: | Amany Mohamed Abdelrahman, Physical Medicine, Rheumatology and Rehabilitation Department, Sohag University |
ClinicalTrials.gov Identifier: | NCT05955573 |
Other Study ID Numbers: |
Soh-Med-23-07-17MS |
First Posted: | July 21, 2023 Key Record Dates |
Last Update Posted: | March 19, 2024 |
Last Verified: | March 2024 |
Individual Participant Data (IPD) Sharing Statement: | |
Plan to Share IPD: | No |
Studies a U.S. FDA-regulated Drug Product: | No |
Studies a U.S. FDA-regulated Device Product: | No |
knee osteoarthritis Aging Metabolic Syndrome |
Osteoarthritis Osteoarthritis, Knee Metabolic Syndrome Arthritis Joint Diseases Musculoskeletal Diseases |
Rheumatic Diseases Insulin Resistance Hyperinsulinism Glucose Metabolism Disorders Metabolic Diseases |