Registry of Multicenter Brain-Heart Comorbidity in China (BHC-C)
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ClinicalTrials.gov Identifier: NCT05961748 |
Recruitment Status :
Recruiting
First Posted : July 27, 2023
Last Update Posted : September 21, 2023
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This study is a multi-center, prospective, registry study. This research was supported by the National Key Research and Development Program. To establish a domestic multi-center, large-scale "brain-heart comorbidity" dynamic database platform including clinical, sample database, image and other multi-dimensional information requirements, through the construction of a multi-center intelligent scientific research integration platform based on artificial intelligence.
Any of newly diagnosed cardiovascular related diseases were identified via ICD-10-CM codes: I21, I22, I24 (Ischaemic heart diseases) [i.e., ACS], I46 (cardiac arrest), I48 (Atrial fibrillation/flutter), I50 (Heart failure), I71 (Aortic disease), I60 (subarachnoid hemorrhage), I61 (intracerebral hemorrhage), I63 (Cerebral infarction), I65 (Occlusion and stenosis of precerebral arteries), I66 (Occlusion and stenosis of cerebral arteries), I67.1 (cerebral aneurysm), I67.5 (moyamoya diseases), Q28.2 (Arteriovenous malformation of cerebral vessels).
The data is stored on the brain-heart comorbidity warehouse via a physical server at the institution's data centre or a virtual hosted appliance. The brain-heart comorbidity platform comprises of a series of these appliances connected into a multicenter network. This network can broadcast queries to each appliance. Results are subsequently collected and aggregated. Once the data is sent to the network, it is mapped to a standard and controlled set of clinical terminologies and undergoes a data quality assessment including 'data cleaning' that rejects records which do not meet the brain-heart comorbidity quality standards. The brain-heart comorbidity warehouse performs internal and extensive data quality assessment with every refresh based on conformance, completeness, and plausibility (http://10.100.101.65:30080/login).
Condition or disease | Intervention/treatment |
---|---|
Ischemic Heart Disease Cardiac Arrest Atrial Fibrillation Heart Failure Aortic Diseases Subarachnoid Hemorrhage Intracerebral Hemorrhage Cerebral Infarction Occlusion and Stenosis of Precerebral Arteries Occlusion and Stenosis of Cerebellar Arteries Cerebral Aneurysm Moyamoya Disease Arteriovenous Malformation of Cerebral Vessels | Other: Multi-disciplinary assessment |
Study Type : | Observational |
Estimated Enrollment : | 100000 participants |
Observational Model: | Cohort |
Time Perspective: | Prospective |
Official Title: | Registry of Multicenter Brain-Heart Comorbidity in China |
Actual Study Start Date : | January 1, 2012 |
Estimated Primary Completion Date : | December 31, 2032 |
Estimated Study Completion Date : | December 31, 2032 |
- Other: Multi-disciplinary assessment
Multi-disciplinary assessment
- Rate of Participants with Composite of All-Cause Mortality and Cardiovascular Outcomes [ Time Frame: At discharge/30 days ]The occurrence of all-cause mortality, coronary artery disease event, stroke (ischemic or hemorrhagic), heart failure, or atrial fibrillation etc.
- All-Cause Mortality [ Time Frame: At discharge/30 days ]The occurrence of death
- Rate of Participants with Composite of Cardiovascular Outcomes [ Time Frame: At discharge/30 days ]The occurrence of coronary artery disease event, stroke (ischemic or hemorrhagic), heart failure, or atrial fibrillation etc.
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Ages Eligible for Study: | 18 Years and older (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
- age > 18 years old
- Any of newly diagnosed cardiovascular-related diseases were identified via ICD-10-CM codes: I21, I22, I24 (Ischaemic heart diseases) [i.e., ACS], I46 (cardiac arrest), I48 (Atrial fibrillation/flutter), I50 (Heart failure), I71 (Aortic disease), I60 (subarachnoid hemorrhage), I61 (intracerebral hemorrhage), I63 (Cerebral infarction), I65 (Occlusion and stenosis of precerebral arteries), I66 (Occlusion and stenosis of cerebral arteries), I67.1 (cerebral aneurysm), I67.5 (moyamoya diseases), Q28.2 (Arteriovenous malformation of cerebral vessels).
Exclusion Criteria:
·refuse to participate in the registry
Inclusion Criteria:
- age > 18 years old
- Any of newly diagnosed cardiovascular-related diseases were identified via ICD-10-CM codes: I21, I22, I24 (Ischaemic heart diseases) [i.e., ACS], I46 (cardiac arrest), I48 (Atrial fibrillation/flutter), I50 (Heart failure), I71 (Aortic disease), I60 (subarachnoid hemorrhage), I61 (intracerebral hemorrhage), I63 (Cerebral infarction), I65 (Occlusion and stenosis of precerebral arteries), I66 (Occlusion and stenosis of cerebral arteries), I67.1 (cerebral aneurysm), I67.5 (moyamoya diseases), Q28.2 (Arteriovenous malformation of cerebral vessels).
Exclusion Criteria:
·refuse to participate in the registry
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT05961748
Contact: Xiaolin Chen, MD | 13810624845 | cxl_bjtth@163.com | |
Contact: Fa Lin, MD | 13681107240 | 13681107240@163.com |
China, Beijing | |
Beijing Tiantan Hospital, Capital Medical University | Recruiting |
Beijing, Beijing, China, 100070 | |
Contact: Fa Lin, MD 13681107240 13681107240@163.com | |
Beijing Anzhen Hospital, Capital Medical University | Not yet recruiting |
Beijing, Beijing, China | |
Contact: Ming Gong, MD | |
Contact: Hai Gao, MD | |
Beijing Chaoyang Hospital, Capital Medical University | Not yet recruiting |
Beijing, Beijing, China | |
Contact: Xiaojuan Guo, MD | |
Chinese People's Liberation Army (PLA) General Hospital | Not yet recruiting |
Beijing, Beijing, China | |
Contact: Hang Zhu, MD | |
Peking University First Hospital | Not yet recruiting |
Beijing, Beijing, China | |
Contact: Wei Ma, MD | |
Contact: Xinggang Wang, MD | |
Xuanwu Hospital, Capital Medical University | Not yet recruiting |
Beijing, Beijing, China | |
Contact: Yingqi Xing, MD | |
China, Fujian | |
The First Affiliated Hospital of Fujian Medical University | Not yet recruiting |
Fuzhou, Fujian, China | |
Contact: Dezhi Kang, MD | |
The First Affiliated Hospital of Xiamen University | Not yet recruiting |
Xiamen, Fujian, China | |
Contact: Sifang Chen, MD | |
China, Guangdong | |
Shenzhen Qianhai Shekou Free Trade Zone Hospital | Not yet recruiting |
Shenzhen, Guangdong, China | |
Contact: Zhiwei Wang, MD | |
China, Heilongjiang | |
The First Affiliated Hospital of Harbin Medical University | Not yet recruiting |
Harbin, Heilongjiang, China | |
Contact: Huaizhang Shi, MD | |
China, Henan | |
The First Affiliated Hospital of Zhengzhou University | Not yet recruiting |
Zhengzhou, Henan, China | |
Contact: Dongming Yan, MD | |
Contact: Guosheng Zhou, MD | |
China, Shanghai | |
Huashan Hospital of Fudan University | Not yet recruiting |
Shanghai, Shanghai, China | |
Contact: Bin Xu, MD | |
Contact: Feng Xu, MD | |
China, Shanxi | |
Shanxi Provincial People's Hospital | Not yet recruiting |
Shanxi, Shanxi, China | |
Contact: Shaohua Ren, MD | |
China, Yunnan | |
The Second Affiliated Hospital of Kunming Medical University | Not yet recruiting |
Kunming, Yunnan, China | |
Contact: Jun Pu, MD |
Study Chair: | Shuo Wang, MD | Beijing Tiantan Hospital | |
Study Director: | Yong Cao, MD | Beijing Tiantan Hospital | |
Principal Investigator: | Dong Xu, MD | Beijing Tiantan Hospital | |
Principal Investigator: | Zening Jin, MD | Beijing Tiantan Hospital | |
Principal Investigator: | Hao Wang, MD | Beijing Tiantan Hospital | |
Principal Investigator: | Shuai Kang, MD | Beijing Tiantan Hospital | |
Principal Investigator: | Yu Chen, MD | Beijing Tiantan Hospital | |
Principal Investigator: | Qingyuan Liu, MD | Beijing Tiantan Hospital | |
Principal Investigator: | Runting Li, MD | Beijing Tiantan Hospital | |
Principal Investigator: | Heze Han, MD | Beijing Tiantan Hospital | |
Principal Investigator: | Wenxiong Song, MD | Beijing Tiantan Hospital | |
Principal Investigator: | Jionghao Xue, MD | Beijing Tiantan Hospital | |
Principal Investigator: | Minghao Liu, MD | Beijing Tiantan Hospital |
Responsible Party: | Xiaolin Chen, MD, Director, Beijing Tiantan Hospital |
ClinicalTrials.gov Identifier: | NCT05961748 |
Other Study ID Numbers: |
KY2022-221-02 |
First Posted: | July 27, 2023 Key Record Dates |
Last Update Posted: | September 21, 2023 |
Last Verified: | September 2023 |
Studies a U.S. FDA-regulated Drug Product: | No |
Studies a U.S. FDA-regulated Device Product: | No |
Subarachnoid Hemorrhage Cerebral Hemorrhage Cerebral Infarction Intracranial Aneurysm Moyamoya Disease Atrial Fibrillation Myocardial Ischemia Coronary Artery Disease Arteriovenous Malformations Aortic Diseases Constriction, Pathologic Hemorrhage Heart Diseases Cardiovascular Diseases Arrhythmias, Cardiac |
Pathologic Processes Infarction Ischemia Necrosis Pathological Conditions, Anatomical Aneurysm Vascular Diseases Intracranial Hemorrhages Cerebrovascular Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Congenital Abnormalities Coronary Disease Arteriosclerosis |