1.01.05 2024:05:13 23:37:50.640 ALL 494743 494743 1 1000 1000 NCTId OrgFullName BriefTitle StartDate Condition Keyword InterventionName EnrollmentCount LocationFacility LocationCity LocationState LocationZip LocationCountry NCT06414057 University of Edinburgh HPV Equity Study: Exploring Cervical Cancer Control in Scotland for Women With Experience of Priority Risks June 1, 2024 Human Papilloma Virus Offering opportunistic HPV vaccine during routine sexual health clinic visits 500 NCT06414044 University of Florence Italian Real-life obServational Study on the effecTiveness, sAfety and Tolerability of Atogepant in Migraine Patients May 9, 2024 Migraine Migraine With Aura Migraine Without Aura Chronic Migraine Headache Medication overuse headache Pain Migraine prevention Gepant Atogepant 60 mg 100 SOD Centro Cefalee e Farmacologia Clinica, AOU Careggi Fondazione Policlinico Campus Bio-Medico Florence Roma 50134 00128 Italy Italy NCT06414031 Martin-Luther-Universität Halle-Wittenberg Tranexamic Acid for Reduction of Transfusion in Abdominal Surgery June 1, 2024 Surgical Blood Loss Transfusion-dependent Anemia Abdomen Disease Tranexamic Acid Placebo 850 University Hospital, Dpt. of Abdominal, Vascular and Endocrine Surgery Halle (Saale) 06120 Germany NCT06414018 Tongji Hospital Effect of Equivalent Dose Sufentanil and Afentanil in Bronchoscopic Treatment May 20, 2024 Effect of Drug Afentanil sufentanil bronchoscopy Recovery time Alfentanil 80 Aijun Xu Hubei Wuhan 430000 China NCT06414005 Tego Science, Inc. A Phase 2b/3 Study of TPX-115 on Partial-thickness Rotator Cuff Tear April 15, 2024 Partial Thickness Rotator Cuff Tear TPX-115 Placebo (Saline) 166 Seoul National University Bundang Hospital Seongnam-si Gyeonggi-do 13620 Korea, Republic of NCT06413992 Cancer Institute and Hospital, Chinese Academy of Medical Sciences Camrelizumab Plus Fluzoparib for TP-53 Mutated Endometrial Cancer May 10, 2024 Endometrial Carcinoma TP53 Mutation Recurrent or Metastatic TP53-mutated, Endometrial Carcinoma,Camrelizumab, Fluzoparib Fluzoparib Camrelizumab paclitaxel (albumin bound) Carboplatin injection Carboplatin External irradiation 117 Cancer Hospital, Chinese Academy of Medical Sciences Beijing Beijing 100021 China NCT06413979 The National Center on Addiction and Substance Abuse at Columbia University Family Support Protocol for Adolescent Internalizing Disorders April 1, 2025 Internalizing Disorders Substance Use Disorders Family Support Protocol for Adolescent Internalizing Disorders (Fam-AID) 60 NCT06413966 Chiang Mai University Study Compares Pneumothorax Recurrence: Absorbable Mesh vs. Pleurectomy in Primary Spontaneous Pneumothorax. May 1, 2024 Primary Spontaneous Pneumothorax Primary Spontaneous Pneumothorax Video-assisted Thoracoscopic Surgery Apical pleurectomy Partially absorbable mesh coverage Recurrence rate of pneumothorax Partially absorbable mesh Apical pleurectomy 24 Department of surgery, Faculty of medicine, Chiang Mai University Hospital Chiang Mai Chaing Mai 50200 Thailand NCT06413953 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. A Clinical Study of TQB3107 Tablets in Patients With Malignant Tumors May 2024 Advanced Cancers TQB3107 Tablets 140 Sun Yat-sen University Cancer Cen Guangzhou Guangdong 510060 China NCT06413940 China National Center for Cardiovascular Diseases Exploring the Clinical Efficacy of Remote Management Applications Through Comprehensive Physical Therapy for Patients With Moderate to Severe Sleep Apnea May 2024 OSAHS Oropharyngeal Muscle Training Aerobic Exercise Comprehensive Physical Therapy M-health OSAHS Comprehensive physical therapy m-health Myofunctional Therapy Inspiratory Muscle Training Aerobic Exercise 105 NCT06413927 Children's Hospital of Philadelphia Novice Driver Education and Crash Reduction May 2024 Risk Reduction Behavior Injuries Accident, Traffic Development, Adolescent Injury prevention Adolescent development Learner drivers Crash risk reduction Novice drivers Risky Driving Teens Online Vehicle and Driver Safety Training Online Driver Skills Training Behind-the-Wheel Driver Training 1200 NCT06413914 Diakonhjemmet Hospital Evaluation of Cognitive Behavioral Therapy for Long-term Pain in Rheumatic Disease, Including Validation of AE-FS January 16, 2024 Rheumatic Diseases Pain, Chronic "Cognitive behavioral therapy" Long-term pain Avoidance-Endurance Questionnaire Rheumatic disease Cognitive behavioral Therapy 200 Diakonhjemmet Sykehus Oslo 0319 Norway NCT06413901 Cairo University TIP Repair of Distal Penile Hypospadias Using Rapidly Absorbable Braided Vs Slowly Absorbable Monofilament Sutures September 1, 2021 Hypospadias Repair TIP 69 Cairo University Cairo 02 Egypt NCT06413888 Baylor College of Medicine Nasogastric Decompression Following Pancreaticoduodenectomy June 1, 2018 Pancreatic Head Neoplasm Delayed Gastric Emptying Post Operative Ileus Whipple Procedure pancreaticoduodenectomy 230 Baylor college of medicine Houston Texas 77030 United States NCT06413875 Bartın Unıversity Effectiveness of Education Specific to Menopause Symptoms April 1, 2023 Menopause Genital image menopause woman symptom quality of life education 158 Ebru Cirban Ekrem Bartin 74100 Turkey NCT06413862 Baoding First Central Hospital Ciprofol Versus Propofol in Patients Undergoing Painless Hysteroscopy May 10, 2024 Painless Hysteroscopy Ciprofol Propofol 188 NCT06413849 The Hong Kong Polytechnic University Telephone-coached "Graphic Narrative" Bibliotherapy for Dementia Caregivers September 2024 Dementia Caregiver Depressive Symptoms Caregiving Appraisal Telephone coached graphic narrative bibliotherapy Control group 128 NCT06413836 University of Nove de Julho Evaluation of Photodynamic Therapy in Pieces With Presence of Fistula. May 1, 2024 Periodontitis Fistula : Periodontitis, Fistula aPDT, Methylene Blue. aPDT Endodontic treatment 30 UCU Montevideo 11200 Uruguay NCT06413823 IRCCS Centro Neurolesi "Bonino-Pulejo" Prevention and Treatment of Cardiovascular Disease May 9, 2024 Cardiovascular Disease Cardiovascular disease neuropsychological depression anxiety psychoeducation dysphagia caregiver sleep disorders altered pneumophonic coordination 218 Irccs Centro Neurolesi Bonino Pulejo Messina Sicilia 98066 Italy NCT06413810 Unilever R&D A Randomised, Double-blind, Placebo-controlled, Crossover Study to Evaluate the Effects of a Food Ingredient on Self-reported Stress in Healthy Adults June 2024 Stress Calmarell Placebo 49 Atlantia Clinical Trials Cork Co Cork T23 R50R Ireland NCT06413797 UNC Lineberger Comprehensive Cancer Center Little Cigar and Cigarillo Warnings for Youth June 2024 Little Cigars and Cigarillos (LCC) Using cigarette warnings youth smoke cigars nicotine addiction cancer prevention Black or African American youth Survey FDA-proposed Text messages Images Surgeon General Text messages 2100 Lineberger Comprehensive Cancer Center at University of North Carolina Chapel Hill North Carolina 27514 United States NCT06413784 Istanbul Medipol University Hospital Examining The Effect of Chronotype Differences on Sleep Quality and Pregnancy Symptoms in Pregnant Women April 1, 2022 Chronotype Pregnancy Complications Morning chronotype Intermediate chronotype Evening chronotype 85 Istanbul Medipol University Istanbul Turkey NCT06413771 Uludag University Only Gonadotropin Vs. Letrozole Combined Gonadotropin Stimulation in IUI Cycles January 1, 2023 Infertility Unexplained unexplained infertility letrozole gonadotropin intrauterine insemination Letrozole 2.5mg Gonadotropin 131 Uludag University Faculty of Medicine Bursa Gorukle 16085 Turkey NCT06413758 Istanbul University - Cerrahpasa (IUC) Attentional Focus in Virtual Reality May 15, 2024 Attentional Focus in Virtual Reality Postural Control Virtual Reality Focus of Attention 38 NCT06413745 Jiangsu HengRui Medicine Co., Ltd. Phase II Clinical Study of SHR-A1811 in Patients With HER2 Expression / Amplification of Locally Advanced Unresectable or Recurrent Metastatic Biliary Tract Cancer May 2024 HER2 Expression / Amplification in Patients With Biliary Tract Cancer SHR-A1811 65 Zhongshan Hospital，Fudan University Shanghai Shanghai 200032 China NCT06413732 Karabuk University The Effect of Dual Task Training in Patients With Stroke September 1, 2022 Stroke Conventional physiotherapy 30 Tarik Ozmen Karabuk 78050 Turkey NCT06413719 Life University Assessing the Effects of Chiropractic Care in Children With Parent-reported Sensory Processing Disorder August 1, 2024 Sensation Disorders Pediatrics sensation disorders autonomic nervous system HRV heart rate variability 20 Premier Wellness Care (PWC) Chiropractic Crystal Lake Illinois 60012 United States NCT06413706 Eli Lilly and Company A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy June 2024 Glioma Brain tumor Central nervous system (CNS) tumor Spinal cord tumor Cyclin-dependent kinase (CDK) 4/6 inhibitor Abemaciclib Temozolomide 45 Phoenix Childrens Hospital (PCH) Phoenix Arizona 97557 United States NCT06413693 Pfizer A STUDY TO LEARN HOW THE STUDY MEDICINE CALLED PF-07293893 AFFECTS MUSCLE BIOMARKERS OF HEALTHY ADULTS May 26, 2024 Healthy Participants PF-07293893 Placebo 60 NCT06413680 Regeneron Pharmaceuticals A First-In Human (FIH) Trial to Find Out if REGN10579 is Safe and How Well it Works for Adult Participants With Advanced Solid Organ Malignancies September 5, 2024 Melanoma Clear-Cell Renal-Cell Carcinoma (ccRCC) Advanced Solid Tumors Advanced solid organ malignancies Locally advanced Metastatic Non-uveal Unresectable Primary or secondary resistance to programmed cell death protein 1 (PD-1)/ programmed cell death ligand 1 (PD-L1) REGN10597 150 NCT06413667 Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Assessment of the Alignment of the Atlas and Surrounding Tissues in Chronic Whiplash Associated Disorder April 8, 2024 Chronic Whiplash Associated Disorder Atlas MRI 90 Amsterdam UMC Amsterdam 1105 AZ Netherlands NCT06413654 Shanghai Jiaolian Drug Research and Development Co., Ltd A Phase II/III Clinical Study of B001 Injection in the Treatment of Neuromyelitis Optica Spectrum Disorders(NMOSD) June 20, 2024 Neuromyelitis Optica Spectrum Disorders B001 Placebo 132 Beijing Anzhen Hospital，Capital Medical University Beijing Tiantan Hospital，Capital Medical University Peking University First Hospital The Second Xiangya Hospital of Central South University The First Affiliated Hospital of Fujian Medical University Guangzhou First People's Hospital The First Affiliated Hospital, Sun Yat-sen University The Second Affiliated Hospital of Zhejiang University School of Medicine The First Affiliated Hospital of Shandong First Medical University First People's Hospital of Yunnan Province The First Hospital of China Medical University The Second Hospital of Hebei Medical University First Hospital of Shanxi Medical University Tianjin Medical University General Hospital The First Affiliated Hospital of Wenzhou Medical University Renmin Hospital of Wuhan University Tongji Hospital The Second Affiliated Hospital of the Chinese People's Liberation Army Air Force Medical University Yantai Mountain Hospital in Yantai City Henan Provincial People's Hospital The First Affiliated Hospital of Zhengzhou University Beijing Beijing Beijing Changsha Fuzhou Guangzhou Guangzhou Hangzhou Jinan Kunming Shenyang Shijiazhuang Taiyuan Tianjin Wenzhou Wuhan Wuhan Xi'an Yantai Zhengzhou Zhengzhou China China China China China China China China China China China China China China China China China China China China China NCT06413641 Aarhus University Hospital VIsualization of Coronary Artery Disease for Modification of RISK Factors March 12, 2024 Coronary Artery Disease Non-Obstructive Coronary Atherosclerosis Coronary computed tomography Hypercholesterolemia Follow up at GP Consultation Visualization of CTA images 390 Bjarne L Nørgaard Hospital of South West Jutland Vejle Hospital Aarhus Esbjerg Vejle 7100 Denmark Denmark Denmark NCT06413628 Mansoura University Efficiency of Different Treatment Modalities on Radiation Induced Trismus for Maxillofacial Patients April 11, 2022 Trismus Cancer screw tapered appliance 36 Marwa Aboelez Mansoura Egypt NCT06413615 Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. A Study of FDA022-BB05 in Advanced/Metastatic Solid Tumors May 13, 2024 Advanced Solid Tumor FDA022-BB05 150 Fudan University Shanghai Cancer Center Shanghai China NCT06413602 Shirley Ryan AbilityLab The Synergistic Effects of AIH and FES in Persons With MS August 2024 Multiple Sclerosis Multiple Sclerosis, Relapsing-Remitting Multiple Sclerosis, Secondary Progressive multiple sclerosis plasticity electrical stimulation NMES modalities neuroplasticity motoneuron aih hypoxia acute intermittent hypoxia Acute Intermittent Hypoxia Neuromuscular Electrical Stimulation 20 Shirley Ryan AbilityLab Chicago Illinois 60611 United States NCT06413589 Alexandria University Efficacy of SMOF Lipid in the Management of Acute Poisoning With Clozapine January 1, 2022 Acute Poisoning clozapine poisoning SMOF lipid lipophilic agents SMOF lipid 20% standard treatment for clozapine toxicity 40 Faculty of Medicine Alexandria Egypt NCT06413576 Ain Shams University Homocysteine in Critically Ill Preeclampsia January 19, 2024 Pre-Eclampsia Critical Illness homocysteine measurement 75 Ain shams University Ain shams university Cairo Cairo القاهرة 11591 Egypt Egypt NCT06413563 Sohag University Analysis of Peripheral Blood Lymphocytes in Patients With Juvenile Idiopathic Arthritis With Respect to Disease Subtypes and Therapy July 15, 2024 Juvenile Idiopathic Arthritis Complete blood count 75 NCT06413550 Ain Shams University The Efficacy of Hibiscus Sabdariffa in Xerostomia April 1, 2024 Radiation-induced Xerostomia xerostomia Hibiscus Sabdariffa Radiation Hibiscus Sabdariffa 40 Ahmed Maher Teaching Hosipital Cairo 11565 Egypt NCT06413537 Spinogenix Phase 2a Study of SPG601 in Adult Men With Fragile X Syndrome June 2024 Fragile X Syndrome Fragile X Syndrome Fragile X Chromosome cognitive outcomes SPG601 Placebo 10 Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229 United States NCT06413524 Taipei Medical University The Effects of Different Vibration Exercises on COPD Patients May 21, 2024 COPD COPD Chronic Obstructive Pulmonary Disease Vibration Therapy Whole-body Vibration Therapy Local Vibration Therapy Sham Comparator 18 Taipei Medical University WanFang Hospital Taipei City Wenshan Dist 116 Taiwan NCT06413511 GlaxoSmithKline A Study to Investigate the Safety and Pharmacological Effect of a Single Intravenous Infusion of Belantamab in Male and Female Participants Aged 18 to 75 With Moderate to Severe Systemic Lupus Erythematosus May 29, 2024 Systemic Lupus Erythematosus Systemic Lupus Erythematosus Belantamab (GSK2857914) Belantamab 16 GSK Investigational Site GSK Investigational Site GSK Investigational Site Medley Peachtree Corners Memphis Florida Georgia Tennessee 33166 30071 38119 United States United States United States NCT06413498 Gilead Sciences A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma October 2024 Multiple Myeloma Multiple Myeloma CAR-T ddBCMA BCMA Anitocabtagene Autoleucel Cyclophosphamide Fludarabine Pomalidomide Bortezomib Dexamethasone Daratumumab Carfilzomib 450 NCT06413485 Toronto Metropolitan University Canadian Beach Cohort Study June 16, 2023 Water-Related Diseases Gastrointestinal Diseases Epidemiology Beach water Water quality Fecal pollution Cohort study Mixed methods Environmental health Level of recreational water contact activities 5000 English Bay Beach and Kitsilano Beach Grand Beach Birch Cove Beach Bay Beach and Nickel Beach Sunnyside and Marie Curtis Park East beaches Vancouver Winnipeg Halifax Fort Erie Toronto British Columbia Manitoba Nova Scotia Ontario Ontario Canada Canada Canada Canada Canada NCT06413472 Başakşehir Çam & Sakura City Hospital Comparing Formulations of Mechanical Power Using Geometric Methods January 1, 2024 Ventilator-Induced Lung Injury Acute Respiratory Distress Syndrome Mechanical ventilator adjustment for PCV Mechanical ventilator adjustment for VCV 38 Basaksehir Cam Sakura City Hospital Istanbul Turkey NCT06413459 Ospedale San Raffaele Identification of New Biological Markers for the Progression of Mycobacterium Abscessus-induced Lung Disease in Cystic Fibrosis April 8, 2021 Non-Tuberculous Mycobacterial Pneumonia Cystic Fibrosis Lung scRNASec Luminex; scRNAsec 40 Ospedale San Raffaele Milan MI 20132 Italy NCT06413446 Başakşehir Çam & Sakura City Hospital Evaluation of the Effectiveness of Genicular Block in Postoperative Analgesia in Patients Undergoing Knee Arthroscopy June 10, 2024 Effectiveness of Genicular Block in Postoperative Analgesia 40 NCT06413433 Axsome Therapeutics, Inc. Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol April 26, 2024 Binge-Eating Disorder Binge eating disorder BED Solriamfetol Sunosi Axsome Non-stimulant therapy Dopamine norepinephrine reuptake inhibitor Trace amine-associated receptor 1 (TAAR1) agonist Solriamfetol 150 mg Solriamfetol 300 mg Placebo 450 Clinical Research Site Clinical Research Site Clinical Research Site Clinical Research Site Clinical Research Site Clinical Research Site Clinical Research Site Clinical Research Site Clinical Research Site Clinical Research Site Clinical Research Site Clinical Research Site Clinical Research Site Clinical Research Site Clinical Research Site Clinical Research Site Encino Newport Beach San Diego Clermont Jacksonville Orlando Orlando Marietta Overland Park Methuen Saint Charles Cherry Hill Raleigh Memphis Austin San Antonio California California California Florida Florida Florida Florida Georgia Kansas Massachusetts Missouri New Jersey North Carolina Tennessee Texas Texas 91316 92660 92103 34711 32256 32801 32806 30060 66210 01844 63304 08002 27607 38119 73787 78229 United States United States United States United States United States United States United States United States United States United States United States United States United States United States United States United States NCT06413420 Axsome Therapeutics, Inc. SUNOSI® (Solriamfetol) Pregnancy Registry July 31, 2019 Narcolepsy Obstructive Sleep Apnea Pregnant Women and Their Offspring Solriamfetol SUNOSI Axsome Narcolepsy Obstructive Sleep Apnea Non-stimulant therapy Dopamine norepinephrine reuptake inhibitor Pregnancy outcomes Infant outcomes Sunosi (solriamfetol) Other prescription wake-promoting medications or stimulants No treatment 1731 Evidera, a PPD business unit PPD, Inc. Morrisville Wilmington North Carolina North Carolina 27560 28401 United States United States NCT06413407 Ataturk University Tai Chi Exercise and Receptive Music Therapy for the Elderly May 15, 2024 Elderly Exercise Therapy Tai Chi Exercise Receptive Music Therapy Elderly Vulnerability Depression Tai Chi Exercise Receptive Music Therapy Experimental 120 NCT06413394 Ardahan University Virtual Reality, Empathy and Environmental Ethics. October 15, 2022 Virtual Reality environmental education 90 Ardahan Devlet Hastanesi Ardahan Centrium 75000 Turkey NCT06413381 IRCCS Azienda Ospedaliero-Universitaria di Bologna RISK FACTORS FOR NON-RESPONSE TO HORMONAL MEDICAL THERAPY IN PATIENTS WITH ENDOMETRIOSIS April 19, 2024 Endometriosis pelvic pain endometriosis hormone therapy therapeutic non-response risk factors reproduction infertility 250 IRCCS Azienda Ospedaliero-Universitaria, Policlinico Sant'Orsola Bologna BO 40138 Italy NCT06413368 Children's Hospital Los Angeles Maralixibat in Patients With Cystic Fibrosis and Constipation, A Within-Subjects Pilot Study July 1, 2024 Constipation Chronic Idiopathic Cystic Fibrosis Maralixibiat Cystic Fibrosis Chronic Constipation Bristol Stool Maralixibat 9.5 MG/ML [Livmarli] 20 Children's Hospital Los Angeles Los Angeles California 90027 United States NCT06413355 Abramson Cancer Center at Penn Medicine FAPI-74 PET/CT in Adults With Fibrosis May 30, 2024 Fibrosis (Morphologic Abnormality) [F-18]-FAPI-74 25 University of Pennsylvania Philadelphia Pennsylvania 19104 United States NCT06413342 Zhejiang Cancer Hospital Sintilimab After Concurrent Chemoradiotherapy in Elderly Patients With Esophageal Squamous Cell Carcinoma June 1, 2024 Esophageal Cancer Chemoradiotherapy Sintilimab Immunotherapy Elderly Patients Sintilimab 191 NCT06413329 Peking Union Medical College Hospital The Association Between Physical Activity Level and Post-operative Prognosis June 2024 Elective Operation Patients preoperative physical activity level within 3 months 324 NCT06413316 Yale University ABC-CT Pre-School Feasibility Study August 1, 2024 Autism Spectrum Disorder Biomarker 50 Children's Hospital Los Angeles Yale Child Study Center Boston Children's Hospital Duke University University of Washington Los Angeles New Haven Boston Durham Seattle California Connecticut Massachusetts North Carolina Washington 90027 06510 02445 27708 98195 United States United States United States United States United States NCT06413303 Peking Union Medical College Hospital The Effect of Experiential Classroom on Establishing Healthy Behaviors During Pregnancy December 20, 2023 Experiential Classroom Health Behavior Preconception Education Adverse Pregnancy Outcome Experiential Classroom 136 Department of ob gyn, Peking Union Medical College Hospital Beijing 100730 China NCT06413290 Antalya Training and Research Hospital Doppler Evaluation of Ultrasound-guided Pectointercostal Fascial Plane Block in Cardiac Surgery May 15, 2024 Cardiovascular Surgery regional anesthesia postoperative pain doppler ultrasound cardiovascular surgery PIFP block group Control group 40 University of Health Sciences, Antalya Training and Research Hospital Antalya Muratpaşa Turkey NCT06413277 Ainsworth Institute of Pain Management Targeting the Conus Medullaris With ECAP-Controlled Closed-Loop SCS for Treatment of Chronic Pelvic Pain: HOPE Trial February 5, 2024 Chronic Pelvic Pain Pudendal Neuralgia Chronic Pelvic Pain Pudendal Neuralgia Levator Ani Syndrome Saluda Evoke Smart SCS System 20 Ainsworth Institute of Pain Management New York New York 10022 United States NCT06413264 All India Institute of Medical Sciences, Bhubaneswar Ultrasonography Guided Pneumoperitoneum for Laparoscopic Surgery in Morbidly Obese Patients June 1, 2024 Pneumoperitoneum Morbid Obesity Bariatric Surgery Candidate pneumoperitoneum closed technique Veress needle ultrasonography-guided morbidly obese bariatric surgery metabolic surgery access-related injury Ultrasonography guided Veress needle insertion for creating pneumoperitoneum Veress needle will be inserted blindly as a closed technique for creating pneumoperitoneum 40 All India Institute of Medical Sciences Bhubaneswar Odisha 751019 India NCT06413251 University of Texas, El Paso Clinical Effectiveness of Boxing Training in Individuals With Elevated Blood Pressure or Stage 1 Hypertension January 15, 2020 Elevated Blood Pressure Hypertension Boxing Training Control flexibility 24 The University of Texas at El Paso El Paso Texas 79968 United States NCT06413238 Tarbiat Modarres University Rationale and Design of Diabetes Management With Curcumin and Saffron (DMCS): a Randomised, Three Blind -Blind, Placebo-controlled Study June 10, 2024 Women of Reproductive Age Diabetes Mellitus diabetes reproductive age curcumin saffron lipid profile sugar profile enterometric indices curcumin, saffron, combined and placebo 120 NCT06413225 Synergy Spine Solutions Post-Market Data Collection Protocol to Evaluate the Performance of the Synergy Disc® September 1, 2024 Cervical Degenerative Disc Disease radiculopathy myelopathy disc replacement motion preservation Synergy cervical disc system 50 Kings College Hospital London United Kingdom NCT06413212 Tongji Hospital Exploratory Study of Precise Therapy for Advanced Tumor Patients With Malignant Hydrothorax or Ascites by Using PTC Drug Sensitivity Testing August 4, 2023 Lung Cancer Breast Cancer Gastric Cancer Colorectal Cancer PTC: Patient-derived tumor-like cell clusters Patient-derived tumor-like cell clusters (PTC) drug sensitivity testing. 55 Tongji Hospital Wuhan Hubei 430030 China NCT06413199 Pakistan Society for Rehabilitation of Differently Abled Hospital Adaptive Response of Brain Towards Resistance Training in Healthy Individuals August 18, 2023 Resistance Training Resistance Training Performance Nervous Response Muscle growth Exercise Induced Performance Hyper Training 1 Repetition maximum training group 100 PSRD Hospital Lahore Punjab 54000 Pakistan NCT06413186 Tarsus University Effect of Placenta Delivery Method on Pain, Bleeding and Comfort May 6, 2024 Placenta Abruptio placenta labor pain birt comfort third stage of labor Uteratonic administration cord clamping delivery of the placenta 140 Tarsus üniversitesi Mersin Tarsus 33400 Turkey NCT06413173 United States Naval Medical Center, San Diego Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric) June 1, 2024 Brain Concussion Brain Trauma Attention Concentration Difficulty Brain Injuries Brain Injuries, Traumatic Neurocognitive Dysfunction Attention Impaired Memory Impairment Mild Traumatic Brain Injury Mild Cognitive Impairment Post Concussive Symptoms Military Health Brain Stimulation Cognitive Training Cognitive Rehabilitation Telehealth Neuromodulation Active tDCS and Cognitive Training Intervention Sham tDCS and Cognitive Training Intervention 160 Naval Medical Center San Diego Minneapolis VA Health Case System San Diego Minneapolis California Minnesota 92134 55417 United States United States NCT06413160 Jordan Collaborating Cardiology Group The Cardiovascular-Renal-Metabolic (CRM) Syndrome Survey in Jordan July 1, 2024 Cardiovascular-renal-metabolic Syndrome 10000 Istishari Hospital Amman 11184 Jordan NCT06413147 Xuanwu Hospital, Beijing Long-term Procedural and Device Related Complications of PFO Closure May 30, 2024 Patent Foramen Ovale PFO closure 100 NCT06413134 SleepRes Inc. TheraPAP Adherence Crossover Study May 10, 2024 Obstructive Sleep Apnea TheraPAP APAP 32 Sleep Centers of Middle Tennessee Murfreesboro Tennessee 37129 United States NCT06413121 Serum Institute of India Pvt. Ltd. Clinical Study to Assess the Immunogenicity and Safety of Hexavalent Vaccine Containing Reduced Dose IPV May 4, 2024 Diptheria Immunization Tetanus Immunization Pertussis Immunization Hepatitis B Immunization Haemophilus Influenzae Type B Immunization Polio Immunization Hexavalent (DTwP-HepB-IPV-Hib) Vaccine Containing Reduced Dose IPV Hexavalent (DTwP-HepB-IPV-Hib) Vaccine Containing Full Dose IPV 1557 NCT06413108 Radboud University Medical Center Safety, Pharmacokinetics, and Plasmodium Falciparum Transmission-reducing Activity of Monoclonal Antibody TB31F in Mali June 2024 Malaria,Falciparum transmission-reducing monoclonal antibody TB31F Normal saline 165 NCT06413095 Presage Biosciences PBI-MST-01 (NCT04541108) Substudy MSD-03: Intratumoral Microdosing of Pembrolizumab Alone and With MK-0482 or MK-4830 in HNSCC or STS June 1, 2022 Head and Neck Squamous Cell Carcinoma Soft Tissue Sarcoma HNSCC head and neck cancer head and neck squamous cell carcinoma STS soft tissue sarcoma intratumoral microdosing microdose injection microdosing in vivo oncology tumor microenvironment multiplexed immunohistochemistry pharmacodynamic biomarkers CIVO master protocol precision oncology spatial biology Pembrolizumab MK-0482 + Pembrolizumab MK-4830 + Pembrolizumab 13 UC Davis Emory Winship Cancer Institute LSU Health Sciences Center - Shreveport Montefiore Medical Center University of North Carolina UC Health Oregon Health & Science University (OHSU) University of Pennsylvania Sarah Cannon Medical Center UT Health Houston University of Washington Sacramento Atlanta Shreveport Bronx Chapel Hill Cincinnati Portland Philadelphia Charleston Houston Seattle California Georgia Louisiana New York North Carolina Ohio Oregon Pennsylvania South Carolina Texas Washington 95817 30308 71115 10467 27599 45219 97239 19107 29406 77401 98109 United States United States United States United States United States United States United States United States United States United States United States NCT06413082 Ospedale San Raffaele Pharmacogenetics of Torasemide and Spironolactone in Hypertension Treatment February 15, 2021 Hypertension Genetic Predisposition Drug Effect hypertension genetics torasemide spironolactone pharmacogenetics Torasemide Spironolactone 38 San Raffaele Hospital IRCCS Ospedale San Raffaele Milan Milan Lombardia 20132 20132 Italy Italy NCT06413069 Charite University, Berlin, Germany Effects of Almonds in Glucose-intolerant Adults (AGAMEMNON) May 20, 2024 PreDiabetes NAFLD almonds dietary treatment diabetes prevention metabolic syndrome Raw whole almonds 150 Charite University Hospital Berlin Berlin 12203 Germany NCT06413056 Ain Shams University Micafungin Versus Amphotercine B in Treatment of Invasive Fungal Infection October 20, 2022 Neonatal Infection Invasive Fungal Infections preterm neonate invasive fungal infection micafungin Micafungin Amphotericin B 56 Ain Shams University Hospitals Cairo Abbassia Egypt NCT06413043 All India Institute of Medical Sciences, Bhubaneswar Study on Efficacy of Add on Selenium in Mild-to-moderate Graves Ophthalmopathy May 6, 2024 Thyroid Eye Disease Graves Ophthalmopathy Thyroid Eye Disease Graves Ophthalmopathy Selenium 78 AIIMS Bhubaneswar Bhubaneswar Odisha 751019 India NCT06413030 University of Americas Slow Gait Speed as an Indicator of Overweight, Dynapenic Obesity and Sarcopenic Obesity in Elderly People in the Community February 1, 2024 Frailty Obesity Sarcopenia Sarcopenic Obesity Gait Speed aged Aged, 80 and over 10 Meter Walk Test 383 Universidad de las Américas Concepción Chile NCT06413017 Tianjin Medical University Cancer Institute and Hospital Nimotuzumab Combined With ICIs for the Treatment of Advanced Liver Cancer After First Line Treatment Failure August 31, 2023 HCC Nimotuzumab ICIs(Immune checkpoint inhibitors) 30 Tianjin Medical University Cancer Institute and Hospital Tianjin China NCT06413004 Sahlgrenska University Hospital, Sweden Brachyspira and Intestinal Allergy-like Immune Reactions in Patients With Irritable Bowel Syndrome (IBS) August 3, 2022 Irritable Bowel Syndrome Food Sensitivity Irritable Bowel Syndrome Food Sensitivity Confocal Laser Endomicroscopy Colonoscopic Antigen Provocation Test Elimination and re-introduction of CLE or COLAP positive food item(s) 200 Mag-tarmlab, Dept of Internal Medicine, Sahlgrenska University Hospital Gothenburg 413 45 Sweden NCT06412991 Wake Forest University Health Sciences Pedal Movement - Implementing Cycling as a Mobility Option July 2024 Ileus bowel function bowel obstruction cycle therapy mobility Cycle Therapy 100 Northeast Acute Care Surgery Concord North Carolina 28025 United States NCT06412978 Wake Forest University Health Sciences Post-Operative Cesarean Section Cosmesis July 2024 Cesarean Delivery cosmetic improvement surgical correction Cosmesis absorbable subcuticular polyglycolic acid staples (INSORB) subcuticular, polyglecaprone suture (Monocryl) 52 Wake Forest University Health Sciences Winston-Salem North Carolina 27157 United States NCT06412965 Pfizer Reliability of Rimegepant for the Acute Treatment of Migraine January 2, 2024 Migraine Disorders 91 Pfizer New York New York 10001 United States NCT06412952 Peking Union Medical College Hospital 68Ga-NOTA-RM26 PET/CT in Glioma Patients October 1, 2022 Glioma 68Ga-RM26 30 Chinese Academy of Medical Science & Peking Union Medical College Hospital Beijing Beijing 100730 China NCT06412939 Orthofix s.r.l. Retrospective Study on Clinical Performance and Safety Profile of Agile Nail June 2024 Fractures, Bone Impending Fracture Deformity; Bone nail intramedullary rigid nail pediatric Agile Nail 45 Leeds Teaching Hospitals NHS Trust Leeds LS9 7TF United Kingdom NCT06412926 Bayer A Study to Learn About How Much Emodepside Gets Absorbed in the Blood and How Food Affects Its Absorption When Given as a New Type of Tablet to Healthy Participants May 15, 2024 Soil-transmitted Helminth Infection Onchocerciasis (River Blindness) Soil-transmitted helminth infection; Onchocerciasis (river blindness) BAY 44-4400 BAY 44-4400 40 NCT06412913 Orthofix s.r.l. Retrospective Study on Clinical Performance and Safety Profile of MJ-Flex Elastic Nail June 2024 Fractures, Bone nail elastic elastic nailing intramedullary pediatric MJ-Flex The New Metaizeau Nail 61 Sheffield Children's NHS Foundation Trust Sheffield S10 2TH United Kingdom NCT06412900 Oslo University Hospital Radiomics and Image Segmentation of Urinary Stones by Artificial Intelligence May 15, 2024 Urinary Stone Renal Colic Obstruction Ureter Urosepsis Urolithiasis Ureter Stone Kidney Stone Urolithiasis Computed tomography Image segmentation Ureteral obstruction Artificial intelligence 500 NCT06412887 National Cheng-Kung University Hospital Effects of Adding Force Control to a VR Game on Brain Activation July 10, 2023 Healthy Aging Virtual Reality functional near infrared spectroscopy Virtual reality headset 24 National Cheng Kung University Tainan 701 Taiwan NCT06412874 Icahn School of Medicine at Mount Sinai Assessment of Supportive Care and Educational Needs to Guide Quality Care Improvements for Patients With Locally Advanced and Metastatic Bladder Cancer September 1, 2023 Screening Tool Focus Group Screening tool 210 Icahn School of Medicine at Mount Sinai New York New York 10029 United States NCT06412861 Ondokuz Mayıs University Ketofol or Fentafol for Procedural Sedation in the Short-term Gynecological Case April 20, 2024 Ketamine Sedation Gynecologic Disease ketamine sedation gynecological case Ketamine Fentanyl 60 Ondokuz Mayıs University Faculty of Medicine Samsun Turkey NCT06412848 Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany JAVEMACS: Japan AVElumab Maintenance And Continuous Treatment Study May 9, 2024 Urothelial Carcinoma Urothelial Carcinoma Avelumab JAVEMACS Locally advanced UC Metastatic UC Avelumab 300 Hirosaki University Hospital Ehime University Hospital Kurume University Hospital Hokkaido University Hospital Sapporo Medical University Hospital Kobe University Hospital Iwate Medical University Hospital Kagawa University Hospital St. Marianna University Hospital Kitasato University Hospital Nara Medical University Hospital Kindai University Hospital Saitama Medical University International Medical Center Juntendo University Hospital Nippon Medical School Hospital National Cancer Center Hospital Teikyo University Hospital Akita University Hospital Kyushu Cancer Center Kumamoto University Hospital University Hospital Kyoto Prefectural University of Medicine Kyoto University Hospital Osaka International Cancer Institute Tokushima University Hospital Toyama University Hospital Yamagata University Hospital Hirosaki Toon Kurume Sapporo Sapporo Kobe Shiwa-gun Kita-gun Kawasaki Sagamihara Kashihara Osakasayama Hidaka Bunkyo-ku Bunkyo-ku Chuo-ku Itabashi-ku Akita Fukuoka Kumamoto Kyoto Kyoto Osaka Tokushima Toyama Yamagata Aomori Ehime Fukuoka Hokkaido Hokkaido Hyogo Iwate Kagawa Kanagawa Kanagawa Nara Osaka Saitama Tokya Tokyo Tokyo Tokyo 036-8563 791-0295 830-0011 060-8648 060-8648 650-0017 028-3695 761-0793 216-8511 252-0374 634-8522 589-8511 350-1298 113-0033 113-8603 104-0045 173-8606 010-0041 811-1347 860-8556 602-8566 606-8507 540-0008 770-0042 930-0194 9902331 Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan Japan NCT06412835 Bilecik Seyh Edebali Universitesi Enteral Nutrition Training With Cooperative Learning May 8, 2024 Educational Problems cooperative learning nursing students enteral nutrition cooperative learning 100 NCT06412822 Brugmann University Hospital Neutrophil Extracellular Traps (NET's) in Prevalent Kidney Stone September 12, 2023 Kidney Stone Blood sampling Urine sampling 500 CHU Brugmann Brussel 1020 Belgium NCT06412809 Mariano Marcos State University Combine Land- and Water-Based Core and Lower Extremity Strength Training in Improving the Jump Performance Among Volleyball and Basketball Players April 26, 2024 Athletes Strength training Core strengthening Jump performance Basketball players Volleyball exercise Combined Land- and Water-Based Exercise Land-Based Exercise Water-Based Exercise 20 Mariano Marcos State University Batac Il 2906 Philippines NCT06412796 TC Erciyes University Postoperative Analgesic Effects of Subcostal Transversus Abdominis Plane Block Versus External Oblique Intercostal Block on Patients Undergoing Gastrectomy June 26, 2024 Postoperative Pain Analgesia SCTAP External Oblique Intercostal block postoperative analgesia 60 University of Erciyes Kayseri Talas 38100 Turkey NCT06412783 Beijing Tiantan Hospital Population-based Investigation of Aneurysm Incidence October 1, 2023 Intracranial Aneurysm Intracranial Aneurysms Screening Blood test blood test 1500 Capital Medical University Affiliated Beijing Tiantan Hospital Beijing Beijing China NCT06412770 Chengdu University of Traditional Chinese Medicine Effect of Tai Chi on Symptoms in Hemodialysis Patients July 1, 2024 Dialysis; Complications Chinese Medicine Quality of Life Tai chi Tai Chi imagery no-intervention 80 NCT06412757 Deakin University Silexan in the Treatment Of Posttraumatic Stress Disorder Trial June 1, 2024 Post Traumatic Stress Disorder posttraumatic stress disorder adjunctive treatment Silexan phytoceutical pharmacotherapy randomized controlled trial Silexan Placebo 224 NCT06412744 Maastricht University Medical Center Determination of the Iodine Status in Pregnant Women in the Netherlands. October 6, 2020 Pregnancy Related Healthy 43 Maastricht UMC+ Maastricht Limburg 6225 HX Netherlands NCT06412731 Al-Mustansiriyah University Comparing the Effectiveness of Papain Based Chemico-mechanical Caries Removal Gel and 38% Silver Diamine Fluoride for Treating Active Caries Lesion of Primary Molars January 2, 2024 Dental Caries in Children CMCR SDF Ceramic bur Cera-bur Brix3000 E-SDF 45 College of Dentistry, Mustansiriyah University Baghdad Al-karkh 10011 Iraq NCT06412718 IRCCS Ospedale San Raffaele Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies May 2024 Rare Diseases Aniridia Neurotrophic Keratopathy Limbal Stem Cell Deficiency Ocular Graft-versus-host Disease Ocular Cicatricial Pemphigoid EEC Syndrome Corneal Neovascularization Rare Eye Diseases Aniridia Neurotrophic Keratopathy Limbal Stem Cell Deficiency Ocular Graft-versus-host Disease Ocular Cicatricial Pemphigoid Corneal Neovascularization Molecular targets Cellular targets Genomic targets NK1R PBMC Substance P VEGF Blood Tear Impression cytology Cytokine 274 NCT06412705 Studio Odontoiatrico Associato Dr. P. Cicchese e L. Canullo Vit D and Post-extractive Bone Turnover October 2, 2023 Vitamin D Deficiency Alveolar Bone Loss Alveolar Bone Resorption Dental Implants, Alveolar Bone Loss, Alveolar Process Tooth extraction, guided bone regeneration and dental implant 14 Studi Odontoiatrici Luigi Canullo Roma RM 00100 Italy NCT06412692 Izmir Katip Celebi University Motivational Interviewing in Adolescents With Epilepsy November 18, 2023 Pediatric ALL Epilepsy Adolescent Motivational Interviewing The Motivational Interviewing Technique 72 İzmirKCU İzmir Çigli 35620 Turkey NCT06412679 Dalhousie University RESETTLE-IDPs: Life-Skills Education and Psychosocial Resilience Building for Displaced Nigerians August 2024 Mental Health Psychosocial Functioning Implementation Science Global Health Conflict Conflict Forced Displacement Internally displaced persons Mental health Psychosocial support Life skills education Mobile health Digital health Humanitarian emergencies Global mental health 500 NCT06412666 Cytokinetics A Study to Evaluate the Effect of Aficamten in Pediatric Patients (Age 12 to <18 Years) With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM). May 2024 Pediatric Symptomatic Obstructive Hypertrophic Cardiomyopathy CK-3773274 CK-274 Aficamten Symptomatic Obstructive Hypertrophic Cardiomyopathy oHCM CEDAR CEDAR-HCM CY 6023 Aficamten Placebo 40 NCT06412653 Children's University Hospital Cologne, Germany Prospective Pilot Trial to Address Feasibility and Safety of Oral Zinc in GNAO1 Associated Disorders June 2024 GNAO1 Dystonia Epilepsy Development Delay Developmental and Epileptic Encephalopathy 17 Neurodevelopmental Disorder With Involuntary Movements Choreoathetosis GNAO1 Zinc Acetate Dihydrate 12 NCT06412640 Nanjing First Hospital, Nanjing Medical University Optimization of Keverprazan-amoxicilli Dual Therapy for Helicobacter Pylori June 1, 2024 H. Pylori Infection Keverprazan Amoxicillin 268 NCT06412627 Changhua Christian Hospital The Effect of Intervention About Dry Mouth and Thirst in Patients With Endotracheal Tube May 2024 Endotracheal Tube Thirst Dry Mouth dry mouth thirst endotracheal tube 4°C frozen normal saline gauze 100 Changhua Christian Hospital Changhua 50006 Taiwan NCT06412614 Central Hospital, Nancy, France Evaluation of Patients With Systemic Sclerosis Without Specific or Associated Autoantibodies September 2, 2024 Systemic Sclerosis disease phenotype 300 CHU Angers CHU Brest CH Dunkerque CHU Grenoble CHU Lille Hospices Civils de Lyon AP-HM CHU Nice APHP CHU Poitiers CHU Reims CHU Rennes Hôpitaux Universitaires de Strasbourg Hôpitaux Universitaires de Strasbourg Angers Brest Dunkerque Grenoble Lille Lyon Marseille Nice Paris Poitiers Reims Rennes Strasbourg Strasbourg France France France France France France France France France France France France France France NCT06412601 Children's Mercy Hospital Kansas City Happy Bob App: A Preliminary Evaluation of Its Use in Youth With Diabetes July 1, 2024 Type 1 Diabetes RPM app 80 NCT06412588 Nanjing First Hospital, Nanjing Medical University Dual Therapy With Vonoprazan Plus Amoxicillin or Doxycycline Versus Bismuth Quadruple Therapy for Helicobacter Pylori Eradication:A Prospective, Multicenter, Open-label Randomized Controlled Study. May 2024 Helicobacter Pylori Infection Helicobacter Pylori Infection Dual therapy Vonoprazan+amoxicillin+doxycycline+bismuth for 14 days Vonoprazan+Amoxicillin Vonoprazan+doxycycline 810 NCT06412575 Nanfang Hospital, Southern Medical University JNT Versus TNT to Guided OGT-overlap Oesophagojejunostomy January 23, 2023 Gastric/Gastroesophageal Junction (g/Gej) Cancer Gastric tumor Gastric/gastroesophageal junction (G/GEJ) Laparoscopic total gastrectomy Overlap anastomosis Joint nasogastric tube JNT Guided OGT-overlap Oesophagojejunostomy TNT Guided OGT-overlap Oesophagojejunostomy 108 Nanfang Hospital, Southern Medical University Guangzhou Guangdong 510515 China NCT06412562 Medical University of Gdansk M3VAS Validation in Polish Population May 9, 2024 Depressive Disorder anhedonia; low mood; suicidality; depression; m3vas The Maudsley 3-item Visual Analogue Scale (M3VAS) 150 Medical University of Gdańsk Gdańsk Poland NCT06412549 Beneficência Portuguesa de São Paulo Effect of a Bundle of Interventions on the Outcomes of Patients With Intracranial Devices (ICP Monitor e EVD) June 1, 2024 Central Nervous System Infections Bacterial resistance Health care Central nervous systen infection Multi-resistant microorganism Health care practices and routines 1300 NCT06412536 Brooklyn Clinical Research Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility May 12, 2024 Cardiovascular Diseases Obesity PreDiabetes Diabetes Type 2 Metabolic Syndrome Blood work 10000 Brooklyn Clinical Research Brooklyn New York 11226 United States NCT06412523 Beneficência Portuguesa de São Paulo Device-related Central Nervous System Infections in Adult Intensive Care Units in Brazil August 15, 2022 Central Nervous System Infections Central Nervous System Infections Catheters 554 Hospital Geral Cleriston Andrade Hospital da Cidade Unimed Vitória Santa Casa de Belo Horizonte Santa Casa de Misericórdia de Passos Santa Casa de Misericórdia de São João del Rei Instituto Estadual do Cérebro Paulo Niemeyer (Pró Saúde- Associação Beneficente de Assistência Social e Hospitalar) Hospital Universitário Onofre Lopes Hospital de Clinicas de Porto Alegre Instituto Baía Sul de Ensino e Pesquisa Irineu May Brodbeck Hospital de Amor (Fundação PIO XII - Barretos) Hospital Unimed Limeira Hospital das Clínicas - FMUSP Ribeirão Preto Hospital e Maternidade Brasil (Rede D´or São Luis) Beneficência Portuguesa de São Paulo Hospital do Coração Hospital São Luiz Itaim Hospital São Paulo Feira De Santana Salvador Vitória Belo Horizonte Passos São João Del Rei Rio De Janeiro Natal Porto Alegre Florianópolis Barretos Limeira Ribeirão Preto Santo André São Paulo São Paulo São Paulo São Paulo BA BA ES MG MG MG RJ RN RS SC SP SP SP SP SP SP SP SP Brazil Brazil Brazil Brazil Brazil Brazil Brazil Brazil Brazil Brazil Brazil Brazil Brazil Brazil Brazil Brazil Brazil Brazil NCT06412510 Case Comprehensive Cancer Center Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT June 1, 2024 Ovarian Cancer Epithelial Ovarian Cancer Pancreatic Adenocarcinoma Ovarian Cancer Neoadjuvant chemotherapy Prehabilitation 30 Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer Center Cleveland Ohio 44195 United States NCT06412497 Masonic Cancer Center, University of Minnesota MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure. July 1, 2024 Severe Aplastic Anemia Acquired Amegakaryocytic Thrombocytopenia Acquired Pure Red Cell Aplasia Paroxysmal Nocturnal Hemoglobinuria HCT RIC SAA PTCy aAT aPRCA Rituximab Rabbit ATG Cyclophosphamide Fludarabine Total Body Irradiation Cell Infusion Post-Transplant G-CSF Tacrolimus Mycophenolate Mofetil 60 NCT06412484 Balgrist University Hospital State vs. Trait Alterations in Low Back Pain October 1, 2023 Low Back Pain Trait vs. State Alterations Pain Free Session Low Back Pain Session (= clinically relevant pain) Experimental Pain Session (= clinically irrelevant pain) 80 Balgrist Campus Zürich 8008 Switzerland NCT06412471 Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. A Phase II Study of SSGJ-707 Combination Therapy in Advanced NSCLC Patients June 2024 First-line Advanced NSCLC Patients SSGJ-707 carboplatin Pemetrexed paclitaxel PD-1/L1 Paclitaxel-albumin 235 Institute of The Hunan Cancer Hospital Changsha China NCT06412458 Beijing Immunochina Medical Science & Technology Co., Ltd. IM83 Clinical Study of CAR-T Cell Therapy in Patients With Relapsed or Refractory Osteosarcoma June 15, 2024 Refractory Osteosarcoma Recurrent Osteosarcoma IM83 CAR-T Relapsed or refractory osteosarcoma IM83 CAR-T Cells 9 Guangdong Provincial People's Hospital Guangdong Guangdong 519041 China NCT06412445 Helwan University Self-Fixating Mesh Versus Mesh Fixation With Tissue Glue in Laparoscopic Inguinal Hernia Repair December 20, 2023 Inguinal Hernia TAPP Self-Fixating Mesh Mesh Fixation Tissue Glue Laparoscopic Transabdominal Inguinal Hernia Repair Inguinal Hernia Repair Laparoscopic transabdominal preperitoneal (TAPP) inguinal hernia repair applying tissue glue for mesh fixation Laparoscopic transabdominal preperitoneal (TAPP) inguinal hernia repair using self-fixating mesh 50 Helwan University Hospitals Cairo 11795 Egypt NCT06412432 Federico II University Exercise Training and Rehabilitation In Cardiac Amyloidosis January 10, 2024 Cardiac Amyloidosis Cardiac Amyloidosis wild-type transthyretin Exercise Training Rehabilitation Cardiomyopathies Heart Failure Exercise training (ET1+ET2) Optimal Medical Therapy (No-ET) 34 Department of Translational Medical Sciences Naples 80131 Italy NCT06412419 Changhai Hospital Multimodal Endoscopic Image Fusion for Assessing Infiltration in Superficial Esophageal Squamous Cell Carcinoma May 15, 2024 Esophageal Neoplasms Malignant Esophageal Neoplasms multimodality Endosonography Magnifying Endoscopy and Endoscopic Ultrasonography 450 Changhai hospital Shanghai China NCT06412406 Assiut University Comparison Between External Oblique Intercostal Plane Block and the Transversus Abdominis Plane Block in Paraumbilical Hernia Repair as Analgesia for Intraoperative and Postoperative Pain. June 2024 Paraumbilical Hernia EOI block TAP block 62 NCT06412393 TCI Co., Ltd. Evaluation of Eye Health Benefits of Black Tomato Extract April 1, 2024 Eye High Myopia Black tomato extract powder Placebo powder 50 Chung Shan Medical University Taichung 402 Taiwan NCT06412380 University of Sharjah Influence of Insertion Torque and Bone Type on Post-operative Pain December 1, 2019 Postoperative Pain Postsurgical Pain Dental Implant Failed Implant insertion 230 University of Sharjah Sharjah 7724 United Arab Emirates NCT06412367 Unity Health Toronto FUNCTIONAL ASSESSMENT FOR SURGERY BY A TIMED WALK May 2024 Surgery-Complications Postoperative Complications Six Minute Walk Test Functional assessment 1672 NCT06412354 Vivheart s.r.l. EasyCrossTM Device-Self-centering Catheter February 12, 2024 Transcatheter Aortic Valve Replacement (TAVR) EasyCross™ first-in human 25 San Raffaele Scientific Institute Milan 20132 Italy NCT06412341 University of the West of England Feasibility Study of ABC for Women Treated for Breast Cancer May 5, 2024 Breast Cancer Female Body Image Feasibility Intervention Cognitive Behavioural Therapy Accepting your Body after Cancer Macmillan body image booklet 120 Centre for Appearance Research, University of the West of England Bristol BS16 1QY United Kingdom NCT06412328 Lokman Hekim Üniversitesi Psychoeducation Program for Parents of Children With DMD June 21, 2023 Psychoeducation Parents Psychological Wellness Duchenne Muscular Dystrophy Psychoeducation 26 Lokman Hekim Universiyt Ankara Cankaya 06510 Turkey NCT06412315 University of Oxford 7T Amygdala and Citalopram Study July 2024 Emotional Processing Cognition Mood Disorders Depressive Disorder Depression Antidepressants Experimental medicine Psychopharmacology Emotional Processing fMRI High field strength fMRI 7 Tesla MRI Citalopram Placebo 50 NCT06412302 Universidad de O´Higgins High Protein Dairy Products and Resistance Exercise in the Elderly June 1, 2023 Dairy Products Whey Protein Resistance Training Older Adults Whey Protein+Resistance Training High protein yogurt+Resistance Training 18 Motion Health and Performance Center Santiago Chile NCT06412289 University Hospital of Ferrara Comparison of the Diagnostic Accuracy Between US-guided Percutaneous Lung Biopsies vs CT-guided in Peripheral Lung Lesions March 8, 2024 Peripheral Lung Lesions US-GUIDED PERCUTANEOUS LUNG NEEDLE BIOPSY CT-GUIDED PERCUTANEOUS LUNG NEEDLE BIOPSY 236 UO Pneumologia AOSP-AUSL Ferrara 44124 Italy NCT06412276 University of Liverpool Out-of-home Consumer Food Purchase Behaviour in the Presence and Absence of Value Pricing and Price Promotions June 1, 2024 Food Selection Healthy Eating Eating Behavior Control Product price promotions removed Bulk buy reductions removed Volume value pricing removed No price-based incentives 2051 University of Liverpool Liverpool Merseyside L69 7ZA United Kingdom NCT06412263 University of Edinburgh Pain Following Root Canal Treatment November 5, 2021 Assessment of Pain After Root Canal Treatment Routine root canal treatment/ retreatment 162 NHS Lothian Edinburgh United Kingdom NCT06412250 Translumina Therapeutics LLP A Multicenter Observational Registry to Evaluate Safety and Performance of Vivo ISAR (SECURE Global Registry) January 10, 2024 Cardiovascular Diseases 2000 Fortis Escorts Heart Institute & Research Centre Shalby Hospital L.P.S Institute of Cardiology Seva Sadan Hospital Yashodha Hospital Aoup Paolo Giaccone University Medical Centres Tergooi MC Delhi Jabalpur Kanpur Miraj Somajiguda Palermo Amsterdam Hilversum 110025 482002 208019 416410 500082 90127 1105 AZ 1213 XZ India India India India India Italy Netherlands Netherlands NCT06412237 Tan Tock Seng Hospital An Exploratory Study of a Wearable Robotic Hand Orthosis June 2024 Stroke Hand exoskeleton robot Robotic hand orthosis RELab tenoexo 20 Tan Tock Seng Hospital Singapore Singapore NCT06412224 Tianjin Medical University Eye Hospital The Preliminary Safety and Efficacy of RRG001 After Vitrectomy in Subjects With Proliferative Diabetic Retinopathy (PDR) December 20, 2023 PDR - Proliferative Diabetic Retinopathy RRG001 6 Tianjin medical university eye hospital Tianjin China NCT06412211 Seoul St. Mary's Hospital A Clinical Feasibility Study of a Photoacoustic Finder December 7, 2021 Sentinel Lymph Node Breast Cancer Photoacoustic Sentinel lymph node detection Photoacoustic finder 129 Seoul St. Mary's hospital Seoul 07345 Korea, Republic of NCT06412198 M.D. Anderson Cancer Center A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations November 30, 2024 Metastatic Colorectal Cancer KRAS G12C Mutations Cetuximab Cemiplimab Adagrasib 16 MD Anderson Cancer Center Houston Texas 77030 United States NCT06412185 Keymed Biosciences Co.Ltd Single Dose Escalation Study of CM383 in Healthy Volunteers June 30, 2024 Alzheimer Disease CM383 Placebo 44 NCT06412172 Massachusetts General Hospital The Natural History and Biological Study of Pulmonary Recurrent Respiratory Papillomatosis (pRRP) April 15, 2024 Recurrent Respiratory Papillomatosis Pulmonary Neoplasm 100 Yale School of Medicine New Haven Connecticut 06520 United States NCT06412159 Kafrelsheikh University Digital Evaluation of Accuracy for Removable Partial Denture Frameworks January 1, 2023 Denture Partial partial denture intra oral digital evaluation accuracy selective laser melting Selective laser melting framework was fabricated using completely digital workflow 18 Nourhan Ragheb Kafr Elsheikh Kafr El Sheikh 6850001 Egypt NCT06412146 Children's Mercy Hospital Kansas City Children's Mercy Teens With Type 1 Diabetes Will Participate in an Online Peer Support Group. July 1, 2024 Type 1 Diabetes Peer Support Group 20 NCT06412133 China Medical University, China Conversations in Light and Shadow: Assessing Phototherapy's Impact on Breast Cancer Patients September 17, 2024 Breast Cancer Breast Cancer Female Randomized Controlled Trial photography 57 China Medical University Hospital China Medical University Hospital Taichung City Taichung City Beitun Dist 406040 406040 Taiwan Taiwan NCT06412120 University of Miami Study Evaluating Safety, Tolerability, and Metabolism of Niraparib September 1, 2024 Ovarian Cancer Niraparib 70 University of Miami Miami Florida 33136 United States NCT06412107 Charles Darwin University Somatic Acupressure for Symptom Cluster Management in Breast Cancer Survivors June 2024 Breast Neoplasm Female Symptom Cluster cancer acupressure fatigue depression insomnia True acupressure Sham acupressure Usual care 108 NCT06412094 Avanta Trading Ltd. Use of a Mobile Health App in Managing Pediatric Atopic Dermatitis March 1, 2022 Atopic Dermatitis Standard care Access to the "AtopicApp" mobile application Virtual oversight through the AtopicApp 66 Samara State Medical University Samara 443079 Russian Federation NCT06412081 Cliniques universitaires Saint-Luc- Université Catholique de Louvain Lung Ultrasound for Physiotherapy in Hospitalized Patients With Respiratory Complications May 10, 2024 Respiratory Complication 30 Cliniques universitaires Saint-Luc Brussels 1200 Belgium NCT06412068 Sun Yat-sen University A Prospective Study: Sintilimab and R-CHOP in PMBCL Treatment June 1, 2024 Primary Mediastinal Large B Cell Lymphoma primary mediastinal large B cell lymphoma sintilimab R-CHOP Combined anti-PD-1 and R-CHOP 32 NCT06412055 Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Bidirectional Tuning of the AFO Stiffness May 5, 2024 Neuromuscular Disorders Neuromuscular disorders dorsiflexor and plantarflexor weakness ankle-foot orthosis (AFO) bidirectional stiffness tuning Gait kinetics and kinematics Walking energy cost Perceived physical functioning NEURO SWING AFO (Fior& Gentz, Lüneburg In Duderstadt, Germany) WalkOn Reaction® (Ottobock, Duderstadt) Matrix Max2® (TruLife, Dublin, Ireland) Matrix® (TruLife, Dublin, Ireland) 10 Department of rehabilitation medicine Amsterdam UMC, location AMC Amsterdam 1105AZ Netherlands NCT06412042 Wecare Probiotics Co., Ltd. Probiotic in Infant Growth, Allergy and Immunity Study June 15, 2024 Healthy Infant ALL Probiotic BLa80 Placebo Maltodextrin 40 Fakultas Kedokteran Universitas Indonesia Jakarta Pusat Jakarta 10430 10430 Indonesia NCT06412029 Wake Forest University Health Sciences Understanding and Enhancing Health-Related Social Needs (HRSN) Screening Among Community Oncology Practices August 2024 Cancer Cancer Health Disparities Non-Interventional 144 NCT06412016 University of Massachusetts, Amherst Urban Gardening and Peer Nutritional Counseling for People With HIV and Food Insecurity May 20, 2024 HIV Food Insecurity Peer Nutritional Counseling + Urban Gardening 500 NCT06412003 University of Vermont Home-based Balance Training in Adults With Multiple Sclerosis July 1, 2024 Multiple Sclerosis Multiple Sclerosis, MS balance training Home-based exercise Home-based balance training 30 NCT06411990 University of Missouri-Columbia Laser In Situ Fenestration Study June 2024 Aortic Aneurysm Endovascular Aneurysm Repair Fenestrated Endovascular Aneurysm Repair Fenestrated Endovascular Aneurysm Repair using the LIFE Device System 15 NCT06411977 University Center of Dental Medicine Switzerland Effect of Dietary Supplements on the Oral Microbiome July 3, 2020 Nutrition, Healthy Vegetable juice 22 University of Wuerzburg University Center for Dental Medicine Würzburg Basel Germany Switzerland NCT06411964 University of Bath Galactooligosaccharide and Aging May 2, 2024 Muscle Loss sarcopenia physical function aging gut microbiome prebiotic Prebiotic Placebo control 30 University of Bath Bath Bath And NE Somerset BA2 7AY United Kingdom NCT06411951 Triaplus AG Klinik Zugersee - Zentrum für Psychiatrie und Psychotherapie Integrated Care After Repeated Psychiatric Hospital Stays - Evaluation of an Interdisciplinary Treatment Program June 1, 2023 High Utilization / Heavy Use Psychiatric Hospitalization Rehospitalization Intensive Care Psychiatric Disorder Chronic Psychiatric Disorder Health Care Utilization Participation in the INTUK care offer at Klinik Zugersee 90 Triaplus AG - Klinik Zugersee Oberwil Zug 6317 Switzerland NCT06411938 Indiana University A Cervical Cancer Prevention Program Kenya: Overcoming Obstacles to Care, Promoting Understanding of HPV Natural History May 2024 Cervical Cancer Prevention Cervical Cancer Kenya cervical cancer prevention Self-collection of vaginal swabs 2500 NCT06411925 SamA Pharmaceutical Co., Ltd The Efficacy and Safety of Atock Dry Syrup With Acute Bronchitis Patients November 10, 2023 Acute Bronchitis Atock Dry Syrup Placebo 260 Soonchunhyang University Seoul Hospital Seoul Korea, Republic of NCT06411912 Nido Biosciences, Inc. A Phase 2 Study of NIDO-361 in Patients With SBMA March 1, 2024 Spinal and Bulbar Muscular Atrophy, Kennedy's Disease NIDO-361 Placebo 54 Rigshospitalet, Klinik for Nerve- og Muskelsygdomme & Copenhagen Neuromuscular Center IRCCS Istituto Neurologico Carlo Besta Kyungpook National University Chilgok Hospital University of College London Hospital (UCLH) Copenhagen Milano Daegu London Denmark Italy Korea, Republic of United Kingdom NCT06411899 MoonLake Immunotherapeutics AG A Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa May 22, 2024 Hidradenitis Suppurativa Hidradenitis Suppurativa Hidradenitis Sweat Gland Diseases Skin Diseases Skin Diseases, Bacterial Suppuration Anti-Inflammatory Agents Sonelokimab Nanobody Apocrine Gland Disease Sonelokimab Placebo 400 NCT06411886 McMaster University Measurements of Inflammation Induced by Allergen Inhalation Challenge in Mild Allergic Asthma July 1, 2024 Mild Asthma Allergen challenge Saline challenge 12 McMaster Cardio-Respiratory Research Lab McMaster University Hamilton Hamilton Ontario Ontario L8N 3Z5 L8N 3Z5 Canada Canada NCT06411873 Indonesia University The Effect of High Protein Enteral Nutrition on Critically Ill Postoperative Children May 30, 2024 Enteral Nutrition Postoperative Critically Ill Children Proteins Enteral Critically ill children Postoperative Control Group Intervention Group 76 RSUPN Dr. Cipto Mangunkusumo Jakarta Pusat DKI Jakarta 10430 Indonesia NCT06411860 Amgen A Study to Assess the Effect of Olpasiran on QT/QTc Intervals in Healthy Participants August 8, 2024 Basic Science QT/QTc Intervals Healthy Participants Olpasiran AMG 890 Placebo Olpasiran Moxifloxacin 32 NCT06411847 University of Dublin, Trinity College The Effectiveness of Virtual Appointments on Compliance With Twin Block Wear November 21, 2023 Compliance, Patient Twin Block Functional Appliances Compliance Virtual appointments 62 HSE Orthodontic Unit, Loughlinstown HSE Orthodontic Unit, Tallaght Dublin Dublin Ireland Ireland NCT06411834 University of California, Los Angeles Mapping Patient Decision-making in Thyroid Cancer January 2025 Thyroid Cancer decision-making Decision navigation tool 50 NCT06411821 Memorial Sloan Kettering Cancer Center Ulixertinib in People With Histiocytic Neoplasms May 7, 2024 Histiocytic Neoplasms Ulixertinib (BVD-523) 23-282 Mitogen-activated protein kinase Ulixertinib 38 Memorial Sloan Kettering Basking Ridge (Consent Only) Memorial Sloan Kettering Monmouth (Limited Protocol Activities) Memorial Sloan Kettering Bergen (Consent Only) Memorial Sloan Kettering Suffolk-Commack (Consent Only) Memorial Sloan Kettering Westchester (Limited Protocol Activities) Memorial Sloan Kettering Cancer Center (All Protocol Activities) Memorial Sloan Kettering Nassau (Consent Only) Basking Ridge Middletown Montvale Commack Harrison New York Uniondale New Jersey New Jersey New Jersey New York New York New York New York 07920 07748 07645 11725 10604 10065 11553 United States United States United States United States United States United States United States NCT06411808 The University of Texas Health Science Center at San Antonio Evaluating Sensory-Adapted Dental Care in Children With Sensory Processing Disorders June 3, 2024 Sensory Processing Disorder sensory processing disorders pediatric dentistry dental anxiety behavioral outcomes sensory adaptation crossover randomized controlled trial sensory modulation disorder sensory over-responsivity Sensory-Adapted Dental Environment 32 UT Health San Antonio San Antonio Texas 78229 United States NCT06411795 Masonic Cancer Center, University of Minnesota Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy November 10, 2023 Duodenal Neoplasm Pancreatic Neoplasm Bupivacaine Hydromorphone Iopamidol Liposomal Bupivacaine Medical Chart Review Questionnaire Administration Thoracic Epidural Analgesia Ultrasound Imaging X-Ray Imaging 78 University of Minnesota/Masonic Cancer Center Minneapolis Minnesota 55455 United States NCT06411782 Istanbul Medipol University Hospital The Effect of Foam Roller Applied to the SCM Muscle on Respiratory Muscle Fatigue May 12, 2024 Healthy Adults Inspiratory Muscle Training Foam Roller Sternocleidomastoid Muscle Inspiratory Muscle Training MIP Foam roller Inspiratory muscle training 27 University of Health Sciences Turkey İstanbul 34668 Turkey NCT06411769 University of Texas, El Paso Evidence-based Intervention to Improve Walking Engagement in El Paso, Texas August 2025 Activity Trackers Physical Activity Walking Challenge Moderate-to-Vigorous-Physical Activity Evidence-based Employer-based 50K4LIfe SMS Text Messaging Individual School 406 University of Texas at El Paso El Paso Texas 79968 United States NCT06411756 UNC Lineberger Comprehensive Cancer Center Physical Activity Centers Empowerment June 1, 2024 Colorectal Neoplasms Physical activity Colorectal Neoplasms Health Equity Black or African American Narrative videos A Fitbit activity tracker Daily text message Monthly Zoom meeting Website access Printed materials Printed materials 72 University of North Carolina at Chapel Hill Chapel Hill North Carolina 27514 United States NCT06411743 The First Hospital of Jilin University Phase II/III of Recombinant Human Albumin Injection September 7, 2021 Hepatic Ascites Hepatic Ascites Recombinant Human Albumin Injection Human Albumin 90 The First Hospital of Jilin University (Leading Site) Chang chun Jilin 130021 China NCT06411730 Celgene A Study to Evaluate the Safety, Tolerability, and Drug Levels of Orally Administered BMS-986368 in Healthy Participants, Healthy Elderly Participants, and Healthy Participants of Japanese Ethnicity May 14, 2024 Healthy Participants Pharmacokinetics Pharmacodynamics BMS-986368 CC-97489 Healthy Volunteers Elderly Volunteers Japanese Volunteers Multiple Ascending Dose Healthy Participants Elderly Participants Japanese Participants BMS-986368 64 Local Institution - 0001 Anaheim California 92780 United States NCT06411717 Suzhou Kerui Medical Technology Co., Ltd A Clinical Trial to Evaluate the Efficacy and Safety of Defocusing Lenses in Delaying Myopia Progression April 7, 2024 Myopia Microstructure lens A Microstructure lens B Control group 156 The First Affiliated Hospital of Soochow University Suzhou District, Suzhou City, Jiangsu Province China NCT06411704 St. Jude Children's Research Hospital Remote Exercise Video Adaptations to Maximize Physical Activity in Childhood Cancer May 2024 Frailty Survivorship Childhood Cancer 20 NCT06411691 Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer August 2024 Colorectal Cancer Pancreatic Cancer KRAS peptide vaccines Anti-PD-1 (anti-check point inhibitor) PD-L1 (check point inhibitor) Balstilimab Botensilimab Cancer Vaccines mKRAS vaccine (peptide vaccine + Poly-ICLC (Hiltonol)) Immunotherapy Colon Cancer Metastatic colon cancer Pancreatic Ductal Adenocarcinoma (PDAC) Metastatic pancreatic cancer Hiltonol KRAS Vaccine with Poly-ICLC adjuvant Balstilimab Botensilimab 50 Sidney Kimmel Comprehensive Cancer Center Baltimore Maryland 21231 United States NCT06411678 Peking Union Medical College Hospital Application of 68GA-labeled CD73 Targeting Probe PET/CT Imaging in the Diagnosis of Breast Cancer May 10, 2024 Breast Cancer 68GA-DOTA-dPNE 50 PUMCH Dongcheng Beijing 100730 China NCT06411665 Peking University First Hospital Effect of Oliceridine Analgesia on Postoperative Nause and Vomiting June 2024 Postoperative Nausea and Vomiting Postoperative nausea and vomiting Laparoscopic colorectal surgery Postoperative analgesia Oliceridine Oliceridine Morphine 250 NCT06411652 Osmaniye Korkut Ata University The Effect of Foot Reflexology and Therapeutic Touch on Fatigue, Depression and Quality of Sexual Life in Women February 27, 2024 Depression Women Health Reflexology Therapeutic Touch 99 Osmaniye New State Hospital Osmaniye 80000 Turkey NCT06411639 Novartis Pharmacokinetics Study of Ianalumab in Chinese Participants With Autoimmune Diseases November 25, 2024 Sjogren Disease Systemic Lupus Erythematosus Pharmacokinetic (PK) Systemic lupus erythematosus (SLE) Sjogren Disease (SjD) VAY736 ianalumab B cell depletion ianalumab 12 NCT06411626 Novartis Home Reported Outcomes in PNH May 15, 2024 Paroxysmal Nocturnal Hemoglobinuria Paroxysmal nocturnal hemoglobinuria PNH home reported outcomes HRO patient-reported outcome PRO real-world data iptacopan PNH-relevant therapies 128 NCT06411613 VA Office of Research and Development Home-based Conservative Care Model for Advanced Kidney Disease June 1, 2024 Chronic Kidney Diseases CKD CC Program 30 VA Puget Sound Health Care System Seattle Division, Seattle, WA Seattle Washington 98108-1532 United States NCT06411600 Vall d'Hebron Institute of Oncology Combination Therapy for BRAF-V600E Metastatic CRCm May 1, 2024 Metastatic Colorectal Cancer Encorafenib Cetuximab Bevacizumab Encorafenib Cetuximab Bevacizumab 94 NCT06411587 Universidad de Zaragoza Analysis of the Correlation Between Ultrasound and Functional Parameters in the Medial Gastrocnemius Muscle in Post-stroke Patients With Spasticity in the Lower Limb February 27, 2024 Stroke Spasticity, Muscle Stroke Ultrasound imaging Spasticity, muscle Function Ultrasound imaging and functional assessment 52 Universidad de Zaragoza Zaragoza Aragón 50009 Spain NCT06411574 University of Western Sydney Body Surface Gastric Mapping vs Gastric Emptying Scintigraphy on Clinical Management in Gastroparesis May 3, 2024 Gastroparesis Gastroparesis Motility Disorders Gastric Emptying Scintigraphy Body Surface Gastric Mapping Gastric Alimetry 40 Western Sydney University Campbelltown New South Wales 2560 Australia NCT06411561 University of Washington A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors July 1, 2024 Critical Illness Delirium Cognitive Impairment Cognitive Decline Alzheimer's Disease Dementia Circadian Dysrhythmia Sleep Disturbance SLEEP + COG COG SLEEP AC 100 NCT06411548 University of Virginia Insulearn Feasibility With MDI June 1, 2024 Type 1 Diabetes Mellitus InPen Dexcom CGM InsuLearn 10 University of Virginia Center for Diabetes Technology Charlottesville Virginia 22903-2981 United States NCT06411535 University of Siena Impact of Ultra-Processed Food Intake on Gingival Tissue Health May 21, 2024 Gingivitis Ultra-processed Food Prevention Full-mouth ultrasonic debridement plus Nutritional counseling Full-mouth ultrasonic debridement 66 AOUS Siena 53100 Italy NCT06411522 University of Siena Clinical and Microbiological Comparison of 0.2% CHX and 0.05% CHX+0.05%CPC Mouthwashes in TPS Patients May 20, 2024 Chlorhexidine Gingivitis Periodontitis Cetylpyridinium Chloride Prevention Mouthwash containing 0.12% CHX (Chlorhexidine) Mouthwash containing 0.05% CHX (Chlorhexidine) and 0.05% CPC (Cetylpyridinium Chloride) 72 AOUS Siena 53100 Italy NCT06411509 The Hong Kong Polytechnic University Integration of Tai Chi and Repetitive Transcranial Magnetic Stimulation for Sleep Disturbance in Older Adults March 1, 2023 Sleep Disturbance Interaction TC plus active rTMS Tai Chi plus sham rTMS TC-alone Low intensity physical exercise 152 Hong Kong Polytechnic University, Department of Rehabilitation Sciences Kowloon Hong Kong NCT06411496 Hospital Galdakao-Usansolo Creation, Implementation and Validation of Intra- and Postoperative Risk Prediction Models June 1, 2018 Postoperative Complications Risk Factors 112745 Hospital Galdakao Usansolo Galdakao Bizkaia 48960 Spain NCT06411483 Concordia University, Montreal Determining the Physiological Mechanisms Behind the ObeEnd Device on Factors Regulating Appetite March 1, 2022 Healthy Obesity, Metabolically Obesity acupuncture obesity appetite weight ObeEnd Band Placebo 27 School of Health, Concordia University Montréal Quebec H4B1R6 Canada NCT06411470 Changhai Hospital Gastrointestinal Microflora and Serum Metabolomics in Patients With Pancreatic Cancer and Chronic Pancreatitis April 20, 2024 Pancreatic Cancer Chronic Pancreatitis 600 Changhai Hospital Shanghai Shanghai 200433 China NCT06411457 Cancer Institute and Hospital, Chinese Academy of Medical Sciences f SHR-A1811 in Combination With Adebrelimab for the Treatment of HER2 Low-expressing Metastatic Breast Cancer May 1, 2024 Breast Cancer SHR-A1811+Adebrelimab 20 National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Beijing Beijing 00 China NCT06411444 Cairo University Effect of Different Nasal Stent Designs With Nasoalveolar Molding Appliance May 15, 2024 Cleft Lip Cleft Lip and Palate Grape Design Nasal Stent 28 Faculty of Dentistry Cairo 00202 Egypt NCT06411431 Swedish Medical Center Early Chest Tube Removal After Surgery for Primary Spontaneous Pneumothorax: A Randomized Controlled Trial October 3, 2023 Primary Spontaneous Pneumothorax Early Chest Tube Removal Standard Chest Tube Removal Apical Chest Tube 200 Swedish Cancer Institute Seattle Washington 98104 United States NCT06411418 State University of New York at Buffalo Evaluation of Flow Diverter Technology Device for Intracranial Aneurysm September 1, 2023 Intracranial Aneurysms Pipeline™ Flex Embolization Device with Shield Technology™ 10 University at Buffalo Neurosurgery Buffalo New York 14203 United States NCT06411405 St George's, University of London Using Machine Learning to Model Early-onset Neonatal Sepsis Risk in Uganda and Zimbabwe April 11, 2024 Neonatal Sepsis Maternal medical history 2500 Makerere University, John Hopkins University St George's, University of London Kawempe London SW17 0RE Uganda United Kingdom NCT06411392 Medical University of Graz SBRT for Ventricular Arrhythmia March 1, 2024 Ventricular Arrythmia stereotactic radiotherapy Stereotactic Antiarrhythmic Radiotherapy 10 Medical University of Graz Graz 8036 Austria NCT06411379 MoonLake Immunotherapeutics AG Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa May 22, 2024 Hidradenitis Suppurativa Hidradenitis Suppurativa Hidradenitis Sweat Gland Diseases Skin Diseases Skin Diseases, Bacterial Suppuration Anti-Inflammatory Agents Sonelokimab Nanobody Apocrine Gland Disease Sonelokimab Placebo 400 NCT06411366 Minicircle Phase I: Safety and Efficacy of an Injectable Follistatin Plasmid Gene Therapy in Humans August 18, 2022 Frailty Aging Follistatin plasmid 43 Global Alliance for Regenerative Medicine Roatan Honduras NCT06411353 Mario Negri Institute for Pharmacological Research Blood Flow Conditions and Sounds in AVFs July 2024 End Stage Renal Disease Arteriovenous fistula Computational modelling Hemodynamic conditions Stenosis MRI acquisition US examination 15 A.O. Papa Giovanni XXIII - U.O. Nefrologia e Dialisi Bergamo 20147 Italy NCT06411340 King's College London Inflammation in Acute Cardiovascular Diseases - the CArdiovascular Inflammation Registry (CAIR) July 2024 Inflammation Cardiovascular Diseases Myocarditis Pericarditis Myocardial Infarction Heart Failure Heart Diseases Inflammation Acute cardiovascular disease Myocarditis Registry Electronic health records Pericarditis Myocardial infarction Observation 1000 NCT06411327 KidSIM Simulation Program Evaluation of the InterFACE-AR System for Cardiopulmonary Arrest: A Multicenter, Randomized Controlled Trial January 1, 2025 Cardiopulmonary Arrest Cardiac Arrest Cardiopulmonary arrest Cardiac arrest Cognitive aid Decision support Simulation Augmented reality LCD Screen 400 NCT06411314 Avva Rus, JSC Efficacy and Safety of Natamycin and Lactulose Vaginal Suppositories in Treatment of Vulvovaginal Candidiasis December 29, 2022 Vulvovaginal Candidiasis, Genital vulvovaginal candidiasis itching Natamycin Lactulose Natamycin + Lactulose 100 mg + 300 mg vaginal suppositories Lactulose 300 mg vaginal suppositories Pimafucin® (natamycin) 100 mg vaginal suppositories 218 Department of Reproductive Medicine and Surgery at the A.I. Evdokimov Moscow State Medical and Dental University Moscow Russian Federation NCT06411301 Jules Bordet Institute A Phase I Study to Assess the Tolerability of 225Ac-DOTATATE in Patients With Refractory and Relapsing Multiple Myeloma Expressing Somatostatin Receptors October 2024 Multiple Myeloma, Refractory Multiple Myeloma in Relapse Multiple Myeloma Progression Multiple Myeloma Somatostatin receptor Radionuclide therapy Actinium-225 Targeted alpha therapy 225Ac-DOTATATE 30 Jules Bordet Institute Brussels 1070 Belgium NCT06411288 Avidity Biosciences, Inc. Phase 3 Global Study of Del-desiran for the Treatment of DM1 May 2024 DM1 Myotonic Dystrophy Myotonic Dystrophy 1 Myotonia Myotonic Dystrophy Type 1 (DM1) Dystrophy Myotonic Myotonic Disorders Steinert Disease Steinert Myotonic Muscular Dystrophy DM1 Myotonic Dystrophy Myotonic Dystrophy 1 Myotonia Myotonic Dystrophy Type 1 (DM1) Dystrophy Myotonic Myotonic Disorders Steinert Disease Steinert Myotonic Muscular Dystrophy HARBOR Avidity Biosciences Avidity AOC 1001 Del-desiran Delpacibart etedesiran AOC 1001 (del-desiran) Placebo 150 NCT06411275 HighTide Biopharma Pty Ltd A Phase 2 Study of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes Inadequately Controlled With Diet and Exercise March 31, 2022 Type 2 Diabetes Mellitus HTD1801 Placebo HTD1801 113 Peking University People's Hospital The Second Hospital of Jilin University The First People's Hospital of Changde City The Fourth Affiliated Hospital of Harbin Medical University Huizhou Municipal Central Hospital Jinan Central Hospital Liaocheng People's Hospital The First Affiliated Hospital of Henan University of Science and Technology Nanjing First Hospital Nanjing Jiangning Hospital Sir Run Run Hospital Nanjing Medical University The First Affiliated Hospital of Nanyang Medical College Yan'an University Affiliated Hospital Affiliated Hospital of Jiangsu University Beijing Chang chun Changde Harbin Huizhou Jinan Liaocheng Luoyang Nanjing Nanjing Nanjing Nanyang Yanan Zhenjiang China China China China China China China China China China China China China China NCT06411262 Hasselt University Pilot Study Investigating Intensity and Quality of Movement Performed During a Parkiboks Session May 8, 2024 Parkinson Disease Boxing Parkiboks 15 UHasselt Diepenbeek Flanders 3590 Belgium NCT06411249 GlaxoSmithKline A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE) June 4, 2024 Systemic Lupus Erythematosus Belimumab Benlysta Efficacy Safety Early Use Systemic Lupus Erythematosus Autoimmune Diseases Belimumab (GSK1550188) 350 NCT06411236 The First Affiliated Hospital of Zhengzhou University Functional Response Characteristics of Brain Under Swallowing Task Paradigm May 10, 2024 Swallowing Disorder Dysphagia Swallowing Substances 30 The first affiliated hospital of zhengzhou university Zhengzhou Henan 450000 China NCT06411223 Yale University Pharmacist-led Intervention for Injectable HIV Treatment for Women With Health-related Social Needs June 1, 2024 Hiv Criminal legal involvement Unstably housed; unhoused Food insecurity Mental health Substance use/ treatment engagement women Long-acting injectable antiretroviral treatment Collaborative drug therapy management model Cabotegravir/Rilpivirine 50 Yale Clinical and Community Research New Haven Connecticut 06519 United States NCT06411210 Yale University Obesity Complicating Type 1 Diabetes: GLP-1 Analogue Anti-obesity Treatment June 2024 Diabetes type1 Obesity Semaglutide Pen Injector Placebo 54 Yale Pediatric Diabetes Center, Adult and Children's Progam New Haven Connecticut 06520 United States NCT06411197 Aalborg University Exploration of Gait Biomechanics and Muscle Pain of the Lower Extremity November 8, 2023 Pain, Acute Musculoskeletal pain Healthy Participants Biomechanics Hypertonic saline injection Isotonic saline injection 36 Aalborg University Aalborg Nordjylland 9000 Denmark NCT06411184 Xuzhou Medical University Safety and Efficacy of Treg Cell in the Treatment of GVHD June 1, 2024 GVHD Regulatory T-Lymphocytes GVHD Regulator T Cells 20 NCT06411171 Xijing Hospital of Digestive Diseases Safety and Efficacy of Pembrolizumab in Combination With FLOT About Gastroesophageal Junction Cancer: June 1, 2024 Gastroesophageal Junction Cancer Pembrolizumab plus chemotherapy (FLOT) 36 NCT06411158 NICHD Pelvic Floor Disorders Network Training for Urinary Leakage Improvement After Pregnancy June 1, 2024 Urinary Incontinence Delivery Complication Urinary Incontinence Pelvic Floor Disorders Physical Therapy Biofeedback Anal Incontinence Interventionist-guided training Home pelvic floor exercises guided by the leva® device Education 216 Kaiser Permanente -- San Diego University of California - San Diego University of Chicago Duke University, Duke Division of Urogynecology and Reconstructive Pelvic Surgery University of Pennsylvania Brown/ Women and Infants Hospital of Rhode Island, Center for Women's Pelvic Medicine and Reconstructive Surgery University of Texas Southwestern Medical Center San Diego San Diego Chicago Durham Philadelphia Providence Dallas California California Illinois North Carolina Pennsylvania Rhode Island Texas 92110 92121 60637 27707 19104 02903 75390 United States United States United States United States United States United States United States NCT06411145 Dompé Farmaceutici S.p.A Open-label Trial to Evaluate Efficacy and Safety of rhNGF on Corneal Thickness Via AS-OCT in Neurotrophic Keratitis April 26, 2024 Neurotrophic Keratitis Neurotrophic Keratopathy Corneal Ulcer stage 3 keratitis cenegermin-bkbj OXERVATE® rhNGF OXERVATE® 0.002% 17 West Coast Eye Institute Harvard Eye Associates Jules Stein Eye Institute Gavin Herbert Eye Institute at UCI Bascom Palmer Eye Center Chicago Cornea Consultants Johns Hopkins Wilmer Eye Institute Tufts Medical Center Minnesota Eye Consultants Associated Eye Care SightMD Baylor Medicine The Eye Institute of Utah Bakersfield Laguna Hills Los Angeles Orange Miami Hoffman Estates Odenton Boston Minnetonka Stillwater Manhasset Houston Salt Lake City California California California California Florida Illinois Maryland Massachusetts Minnesota Minnesota New York Texas Utah 11901 92653 90095 92868 33136 60169 21113 02111 55305 55082 11030 77030 84107 United States United States United States United States United States United States United States United States United States United States United States United States United States NCT06411132 Dompé Farmaceutici S.p.A Multicenter Study to Evaluate Corneal Neurosensory Abnormalities in Patients With Sjögren's Dry Eye March 15, 2024 Sjögren Syndrome Dry Eye Observational Dry Eye Sjögren's dry eye Multinational observational study 182 West Coast Eye Institute University of Colorado Bowden Eye University of Miami Tufts University School of Medicine Minnesota Eye Consultants Eye Associates of North Jersey Weil Cornell Medicine Triangle Eye Consultants Vita Eye Clinic Focus Eye Care University of Pennsylvania Toyos Clinic Periman Eye Institute Bakersfield Aurora Jacksonville Miami Boston Woodbury Dover New York Raleigh Shelby Wilmington Philadelphia Nashville Seattle California Colorado Florida Florida Massachusetts Minnesota New Jersey New York North Carolina North Carolina North Carolina Pennsylvania Tennessee Washington 11901 80045 32256 33136 02111 55125 07801 10021 27617 28150 28405 19104 37215 98119 United States United States United States United States United States United States United States United States United States United States United States United States United States United States NCT06411119 Teesside University Virtual Reality Exergaming on Heart Rate, Perceived Exertion, and Technology Acceptance in Healthy Individuals January 1, 2023 Healthy Physical Activity Virtual Reality Exergame Inactivity, Physical Exergaming Virtual Reality Meta Oculus Quest Heart rate Rate of perceived exertion Technology acceptance Bayesian Inferences Pilot cohort study Healthy Meta Oculus Quest 2™ Virtual Reality Exergaming 9 Teesside University Middlesbrough United Kingdom NCT06411106 Centre for Human Drug Research, Netherlands Deep Phenotyping of Cutaneous Lupus Erythematosus June 2024 Cutaneous Lupus Erythematosus CLE Cutaneous lupus erythematosus Deep phenotyping Immune challenge Healthy volunteers IMIQUIMOD cream 50mg/g 40 Centre for Human Drug Research Leiden Zuid-Holland 2333CL Netherlands NCT06411093 Chang Gung Memorial Hospital Efficacy and Safety of Kinesiology Tape Wrapping for Paronychia Induced by Epidermal Growth Factor Receptor Inhibitors March 2, 2023 Paronychia Epidermal Growth Factor Receptor Inhibitor Kinesiology tape wrapping Conventional treatment including silver nitrate cauterization 24 Kaohsiung Chang Gung Memorial Hospital Kaohsiung 83301 Taiwan NCT06411080 Centre hospitalier de l'Université de Montréal (CHUM) UltraSound Evaluation of Fluid tOleRanCE for Acute Kidney Injury September 1, 2024 Acute Kidney Injury point-of-care ultrasound VExUS Lung ultrasound Fluid therapy acute kidney injury Ultrasound evaluation of fluid tolerance 80 Centre Hospitalier de l'Université de Montréal Montréal Quebec H2X0A9 Canada NCT06411067 United States Naval Medical Center, Portsmouth Investigational Use of Erenumab for the Treatment of Fibromyalgia Pain February 26, 2020 Fibromyalgia Fibromyalgia Chronic pain CGRP Erenumab Saline 5 Naval Medical Center Portsmouth Portsmouth Virginia 23708 United States NCT06411054 Chinese University of Hong Kong The Efficacy of Acu-TENS as an Adjunct Analgesic During USG-MVA June 1, 2024 Pain, Acute Manual vacuum aspiration Ultrasound-guided Acupuncture transcutaneous electrical nerve stimulation Alternative medicine Randomized controlled trial Acu-TENS Sham acu-TENS 108 NCT06411041 National Yang Ming University Effects of a Combined Program of Pelvic Floor Muscle Training and Yoga May 30, 2024 Genitourinary Symptoms Sexual Function Quality of Life Pelvic Floor Muscle Training (PFMT) and yoga 120 NCT06411028 Radboud University Medical Center Factors Determining the Efficacy of Botulinum Toxin for Arm Tremor in Dystonia July 1, 2024 Dystonic Tremor Syndrome Dystonia Tremor Botulinum neurotoxin Botulinum toxin Dystonia Dystonic tremor syndrome Dystonic tremor Tremor associated with dystonia Upper extremity Arm tremor Functional magnetic resonance imaging fMRI Muscle ultrasound Polymyography Muscle ultrasound (Functional) magnetic resonance imaging Clinical assessment Questionnaires 60 NCT06411015 Radboud University Medical Center Prognostic Evaluation Prediction Model Survival Spinal Epidural Metastases January 1, 2021 Predictive Cancer Model 428 Radboud University Nijmegen Medical Center Nijmegen Gelderland 6500 HB Netherlands NCT06411002 Revance Therapeutics, Inc. Phase 2a Study of DaxibotulinumtoxinA-lanm for Injection in Dynamic Forehead Lines and Glabellar Lines May 2024 Glabellar Frown Lines DAXXIFY 30 NCT06410989 Shirley Ryan AbilityLab Evaluation of Sensorimotor Ankle Impairments in Chronic Stroke May 20, 2024 Stroke Robotic Rehabilitation Sensorimotor function Proprioception Motor Control Ankle Rehabilitation 80 Shirley Ryan AbilityLab Chicago Illinois 60611 United States NCT06410976 QED Therapeutics, Inc. Prospective Clinical Assessment Study in Children With Hypochondroplasia May 2024 Children With Hypochondroplasia skeletal dysplasia endochondral ossification hypochondroplasia (HCH) HCH shortened proximal limbs fibroblast growth factor receptor 3 FGFR3 endochondral bone formation short-limb disproportionate dwarfism quality of life in hypochondroplasia dwarfism bone diseases musculoskeletal diseases osteochondrodysplasia genetic diseases inborn functional abilities average growth velocity average height velocity growth bone diseases, developmental genetic diseases, inborn hypochondroplasia 150 QED Investigative Site QED Investigative Site QED Investigative Site QED Investigative Site QED Investigative Site QED Investigative Site QED Investigative Site QED Investigative Site QED Investigative Site QED Investigative Site QED Investigative Site QED Investigative Site QED Investigative Site Oakland Aurora Washington Baltimore Columbia Nashville Madison Parkville Bergen Oslo Coimbra Singapore Vitoria-gasteiz California Colorado District of Columbia Maryland Missouri Tennessee Wisconsin Victoria 94609 80045 20010 21211 65211 37232 53705 3052 5021 0372 3000-602 229899 01008 United States United States United States United States United States United States United States Australia Norway Norway Portugal Singapore Spain NCT06410963 Örebro University, Sweden ReActivate: Physiotherapist Led Intervention for Adolescents With Pain and Psychological Distress. June 1, 2024 Chronic Pain Emotional Distress Reactivate 35 Region Örebro county Örebro 70217 Sweden NCT06410950 Spitalul Clinic de Boli Infecțioase și Pneumoftiziologie Dr. Victor Babeș Timișoara Mechanical Muscle Proprieties in Patient With COPD May 13, 2024 Copd Muscle Weakness Muscle Weakness Condition COPD Muscle tone Muscle stiffness Muscle mechanical proprieties MyotonPRO Assessment of Muscle Biomechanical Properties 80 NCT06410937 Sohag University Evaluation Of Drainless Thyroidectomy For Benign Thyroid Diseases Regarding Surgical Site Complications May 2024 Benign Thyroid Diseases thyroidectomy without drain thyroidectomy with drain 30 Sohag University hospitals Sohag Egypt NCT06410924 Neuraly, Inc. A Phase 2 Study to Evaluate the Efficacy, Safety and Tolerability of DD01 in Overweight/Obese Subjects With MASLD/MASH June 2024 NAFLD NASH Liver Disease Fatty Liver Non-alcoholic fatty liver disease Non-alcoholic steatohepatitis MASH MASLD DD01 Placebo 68 Summit Research Site Summit Research Site Summit Research Site Summit Research Site Maitland West Monroe Brownsville Corpus Christi Florida Louisiana Texas Texas 92751 71291 78520 78404 United States United States United States United States NCT06410911 Sohag University Subcostal Transversus Abdominis Block Versus Erector Spinae Block in Open Cholecystectomy June 1, 2024 Post Operative Pain, Acute Subcostal Transversus Abdominis Plane block in patients undergoing open cholecystectomy surgery. Erector Spinae Block in patients undergoing open cholecystectomy Sbcostal transversus Abdominis block and erector spinae block for both groups 100 NCT06410898 Sohag University Assessment of Hypoxia Inducible Factor and Autophagy Related Genes in Patients With Non-Segmental Vitiligo April 25, 2024 Vitiligo Punch Biopsy 5mm 30 Sohag University hospitals Sohag Egypt NCT06410885 Rhaeos, Inc. Assessment of Flow in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device in Asymptomatic Patients June 2024 Hydrocephalus Thermal Anisotropy Measurement Device 60 NCT06410872 Leiden University Medical Center Risk Taking and Decision-making in Cluster Headache Patients April 23, 2019 Cluster Headache BART Task 140 LUMC Leiden Zuid Holland Netherlands NCT06410859 Lanzhou Institute of Biological Products Co., Ltd Botulinum Toxin Type A for Injection (HengLi®) in the Treatment of Trigeminal Neuralgia April 25, 2024 Trigeminal Neuralgia Botulinum Toxin Type A for Injection (HengLi®) Botulinum Toxin Type A for Injection,also known as "HengLi®" 240 Peking Union Medical College Hospital Beijing Beijing 100730 China NCT06410846 Landstuhl Regional Medical Center Feasibility and Effectiveness of a Novel Neck Training Device March 5, 2024 Injury Prevention TopSpin360 Neck Strengthening Exercise Plan 60 Landstuhl Regional Medical Center Landstuhl Rheinland Pfalz 66849 Germany NCT06410833 Peking Union Medical College Hospital Belimumab After Rituximab in Resistant Primary Juvenile SS March 9, 2024 Sjogren's Syndrome Pediatric ALL Rituximab Belimumab Rituximab Belimumab 15 Peking Union Medical College Hospital Beijing Beijing 100730 China NCT06410820 Karaman Training and Research Hospital Ultrasound Guided Versus Land-mark Method for Spinal Anesthesia in Super Obesity Parturients May 7, 2024 Obesity, Morbid Spinal Anesthesia Cesarean Delivery Ultrasound Procedure/Surgery: Ultrasound method group Landmark method group 60 Karaman Training and Research Hospital Karaman 70200 Turkey NCT06410807 Ohio State University Development of Web-Based Mind-Body Trainings for Adults With Subjective Concerns August 2024 Aging Focus Groups mindfulness-based stress reduction cognitive function mindfulness training aging subjective cognitive decline focus groups lifestyle education Focus groups 60 Department of Psychology, The Ohio State University Columbus Ohio 43210 United States NCT06410794 Molde University College Virtual Reality Training in Occupational Rehabilitation January 1, 2022 Musculoskeletal Diseases Mental Health Disorder Back Pain, Low Anxiety Disorders Depression Virtual reality gaming occupational rehabilitation patient experience quanitative study qualitative study Virtual Reality with Beat Saber 100 Norwegian National Advisory Unit on Occupational Rehabilitation Rauland 3864 Norway NCT06410781 Cairo University Effect of Radial Extracorporeal Shockwave Therapy on Ultrasonography Changes in Patients With Iliotibial Band Syndrome May 20, 2024 Iliotibial Band Syndrome iliotibial band syndrome Radial Extracorporeal Shockwave ultrasonography changes Radial Extracorporeal Shockwave traditional therapy 60 NCT06410768 Maastricht University Medical Center Economic Evaluation of a Multistage Shared Decision-making Program for Type 2 Diabetes: a Pilot Study February 1, 2024 Diabetes Mellitus, Type 2 type 2 diabetes mellitus person-centered care shared decision-making pilot study patient decision aid economic evaluation multistage shared decision-making program 40 Care group Huisarts & Zorg Gorinchem Netherlands NCT06410755 Yonsei University Home-based Gait Rehabilitation Service Using Instrumented Insole March 12, 2024 Gait Disorders, Neurologic gait parameters smart insole home-based exercise monitoring system rehabilitation Monitoring system using a insole-type gait analyzer 30 Yongin Severance Hospital Yongin-si Gyeonggi-do 16995 Korea, Republic of NCT06410742 Kahramanmaras Sutcu Imam University Evaluation of Biopsychosocial Features, Pain, Fatigue, Quality of Life, Swallowing, and Disease-Specific Symptoms in Patients With Primer Sjogren's Syndrome May 15, 2024 Sjogren's Syndrome Sjogren' Syndrome correlation xerostomia dryness 150 Nazli Elif Nacar Kahramanmaraş 46000 Turkey NCT06410729 Peking University Third Hospital Significance of Benign Lymph Node Enlargement in Colorectal Cancer January 1, 2015 Colorectal Neoplasms Malignant Observational study, no intervention 2270 NCT06410716 Peking Union Medical College Hospital A Randomized Controlled Study Comparing Valve-regulated Pleural Drainage System to Traditional Closed Chest Tube Drainage April 20, 2024 Lung Cancer lung cancer thoracic drainage system Valve-regulated pleural drainage system 100 Peking Union Medical College Hospital Beijing Beijing 100730 China NCT06410703 Canwell Biotech Limited CAN1012 Combined With PD-1 in Patients With Solid Tumors May 30, 2024 Advanced Solid Tumor CAN1012 71 Sun Yat-Sen University Sun Yat-Sen Memorial Hospital Guangzhou Guangdong 510535 China NCT06410690 Centro Cardiologico Monzino Trustworthy, Integrated Artificial Intelligence Tools for Predicting High-risk CORonary PlaqueS May 22, 2023 Coronary Artery Disease Coronary Computed Tomography Angiography 4000 Centro Cardiologico Monzino Centro Cardiologico Monzino Milan Milan MI 20131 20131 Italy Italy NCT06410677 Changhai Hospital Changhai Multimodal Esophageal Cancer Cohort June 13, 2018 Esophageal Squamous Cell Carcinoma deep learning Esophageal Squamous Cell Carcinoma immune infiltration DNA Sequencing, RNA Sequencing 110 Changhai hospital Shanghai China NCT06410664 Charles University, Czech Republic Efficiency and Safety of the Prolonged Use of Heat and Moisture Exchangers in ICU May 2024 VAP - Ventilator Associated Pneumonia pneumonia Heat and Moisture Exchange (HME) filter VAP bundle in ICU endotracheal tube occlusion 72-hour HME exchange interval group 24-hour HME exchange interval group 120 NCT06410651 Cancer Institute and Hospital, Chinese Academy of Medical Sciences Nimotuzumab Concurrent With Chemoradiotherapy for Patients With Unresectable Esophageal Squamous Cell Carcinoma March 1, 2023 Esophageal Cancer Nimotuzumab Chemoradiotherapy Chemotherapy Immunotherapy Nimotuzumab with chemoradiotherapy 53 National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China NCT06410638 Istanbul Medipol University Hospital Intercostal Muscle Oxygenation During Exercise Tests May 10, 2024 Muscle Oxygenation exercise capacity test muscle oxygenation intercostal muscle Six Minute Walking Test Shuttle walking test 32 University of Health Sciences Turkey İstanbul 34668 Turkey NCT06410625 Ankara University Evaluation of Response by FLT PET in Mesothelioma April 1, 2024 Pleural Mesothelioma Treatment Response Chemotherapy Effect FLT PET imaging 25 Ankara University Medical School Ankara 06580 Turkey NCT06410612 Washington University School of Medicine Block and Periarticular Injection Study March 4, 2024 Pain, Postoperative regional anesthesia and PAI PAI 200 Washington University School of Medicine Creve Coeur Missouri 63110 United States NCT06410599 University Hospital Tuebingen Pharmacologic Treatment Augmentation in Chronic Depression May 2024 Major Depressive Disorder Ketamine CBASP Augmentation Combination therapy Chronic depression MDD Ketamine Placebo CBASP TAU 60 Universitätsklinikum Tübingen - Klinik für Psychiatrie und Psychotherapie Universitätsklinikum Jena - Klinik für Psychiatrie und Psychotherapie Tübingen Jena Baden-Würtemberg Thüringen 72070 07743 Germany Germany NCT06410586 Jaseng Medical Foundation Integrative Korean Medicine Treatment for Pediatrics After Traffic Accident: Retrospective Chart Review Study and Survey February 5, 2024 Pediatric ALL Traffic Accident 70 Bundang Jaseng Hospital of Korean Medicine Seongnam Gyeonggi-do 13590 Korea, Republic of NCT06410573 KTO Karatay University The Effect Of Self-Breast Examination Training On The Belief Of Breast Health November 6, 2022 Women of Reproductive Age Neoplasms Early Detection of Cancer Breast Neoplasms health education Breast Self-Examination and Practice 98 KTO Karatay University Konya Karatay Turkey NCT06410560 Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria Culture is Care: Training Workshop for Care Workers (VerbaCurant) March 18, 2021 Empathy Well-Being, Psychological Training about storytelling and creative writing: 12 hours Training only about theoretical narrative medicine: 4 hours 175 Azienda Ospedaliera SS Antonio e Biagio e Cesare Arrigo Alessandria Piedmont 15121 Italy NCT06410547 Charite University, Berlin, Germany Processing of Routine Clinical Data Using Large Language Models Such As GPT-4 May 15, 2024 COPD LLM 70 NCT06410534 National Institutes of Health Clinical Center (CC) A Phase II Study Evaluating an Organ Preservation Strategy Using Immune Checkpoint Blockade for Participants With Primary Colorectal or Gastroesophageal Cancer June 10, 2024 Colorectal Cancer Gastroesophageal Cancer nivolumab Ipilimumab Immune Checkpoint Blockade mismatch repair nivolumab ipilimumab 65 National Institutes of Health Clinical Center Bethesda Maryland 20892 United States NCT06410521 University of Trás-os-Montes and Alto Douro Personalised Multicomponent Exercise Programme in Peripheral Arterial Disease May 2024 Peripheral Arterial Disease Intermittent Claudication Peripheral arterial disease Supervised multicomponent exercise programme Exercise Usual care 60 Hospital Centre Hospitalar de Trás-os-Montes e Alto Douro Research Centre in Sports Sciences, Health Sciences and Human Development University of Trás-os-Montes and Alto Douro Vila Real Vila Real Vila Real 5000-508 5000-801 5000-801 Portugal Portugal Portugal NCT06410508 Nova Scotia Health Authority Evaluation of a Brief Intervention to Improve Engagement in Early Intervention Services for Psychosis September 1, 2024 Psychotic Disorders Psychiatric Hospitalization Engagement, Patient early phase psychosis Just Do You 40 Nova Scotia Early Psychosis Program (NSEPP) Halifax Nova Scotia B3H 2E2 Canada NCT06410495 University of South Florida Digital Dyadic Family Based Intervention to Improve Sleep in Children With ODD and Their Parents: NiteCAPP SINCC (Pilot) May 1, 2024 Oppositional Defiant Disorder Insomnia Chronic NiteCAPP SINCC 30 University of South Florida Tampa Florida 33620-8100 United States NCT06410482 Assiut University Analgesia in Pediatric Hypospadias Surgeries May 2024 Hypospadias US guided caudal block Dorsal penile nerve block 26 NCT06410469 Ankara City Hospital Bilkent A Novel Suturing Technique of Cystocele Treatment June 1, 2023 Cystocele anterior colporraphy naturel tissue suture technique rug weaving-like plication technique 65 Ankara City Hospital Ankara 06800 Turkey NCT06410456 Hitit University Schroth Treatment and Proprioception Pathway December 1, 2023 Adolescent Idiopathic Scoliosis Exercise therapy 15 Ahmet Payas Kayseri 38100 Turkey NCT06410443 General Hospital of Shenyang Military Region Efficacy and Safety of Local Glucocorticoids for the Treatment of Radiation-Induced Intestinal Injury July 1, 2024 Radiation-Induced Intestinal Injury Radiation-Induced Intestinal Injury glucocorticoid Dexamethasone Antibiotics, probiotics, vitamins, antidiarrheal drugs, enteral nutrition, and endoscopic argon plasma coagulation 60 Department of Gastroenterology, General Hospital of Northern Theater Command (formerly called General Hospital of Shenyang Military Area) Shenyang Liaoning 110840 China NCT06410430 Guang'anmen Hospital of China Academy of Chinese Medical Sciences Exploration the Mechanism of Ba-Duan-Jin in the Treatment of Fibromyalgia Based on Brain-gut Axis January 31, 2024 Fibromyalgia Ba-Duan-Jin 40 Guang'anmen Hospital Beijing Beijing 100053 China NCT06410417 The First Hospital of Jilin University Ejaculation Abstinence Time and Assisted Reproductive Technology Outcomes May 1, 2024 Fertilization in Vitro in vitro fertilization intracytoplasmic sperm injection Abstinence time Clinical pregnancy rate Embryo quality Shorten abstinence time 500 the first hospital of Jilin University Chang chun Jilin 130000 China NCT06410404 Assiut University Dexmeditomedine as an Adjuvant to Levobupivacaine in Transversus Thoracis Plane Block on the Management of Post-sternotomy Pain in Open-heart Surgeries May 15, 2024 Pain, Postoperative transversus thoracis plane block Dexmedetomidine Levobupivacaine 60 NCT06410391 Assiut University Fetal Brain Ultrasound May 2024 Fetal Anomaly Ultrasound 20 NCT06410378 Zagazig University s Serratus Anterior Block for Perioperative Analgesia May 10, 2024 Mastectomy Postoperative Pain Erector Spinae Block Serratus anterior Block Perioperative Analgesia Erector Spinae Plane Block Serratus Anterior Plane Block controll group 75 Zagazig Zagazig MD 44519 Egypt NCT06410365 Watim Medical & Dental College Impact of Intrathecal vs Intravenous Dexmedetomidine June 1, 2024 Nausea and Vomiting, Postoperative Dexmedetomidine injection 60 NCT06410352 University Medical Center, Kazakhstan Effectiveness of Weight Loss Methods on Lifespan for Metabolic Syndrome March 1, 2023 Metabolic Syndrome metabolic syndrome obesity type 2 diabetes mellitus weight loss telomere length quality of life cost effectiveness analysis Semaglutide, Empagliflozin Minigastric bypass Analimentary detoxication Ramadan fast's weight loss 220 Kuat Pernekulovich Oshakbayev Astana 010000 Kazakhstan NCT06410339 Rocky Vista University, LLC Ultrasound Assessment of Anatomical Changes in the Fingers of Recreational Rock Climbers April 29, 2024 Flexor Tendons Injuries Ultrasound 50 Rocky Vista University Parker Colorado 80112 United States NCT06410326 National MS Center Melsbroek Mapping the Longitudinal, Multidimensional Impact of MS in Relation to Variables Indicative of Neurological Reserve April 1, 2024 Multiple Sclerosis 2600 Nationaal Multiple Sclerose Centrum Melsbroek Melsbroek Vlaams-Brabant 1820 Belgium NCT06410313 Medinol Ltd. First In Human Study to Assess Safety and Efficacy of the ChampioNIR™ Drug Eluting Peripheral Stent in the Treatment of Patients With Superficial Femoral Artery Disease and/or Proximal Popliteal Artery Disease July 15, 2024 Superficial Femoral Artery Stenosis Popliteal Artery Stenosis ChampioNIR Ridaforolimus Eluting Peripheral Stent System 30 NCT06410300 University of Missouri-Columbia Cardiopulmonary Monitoring in Lung Cancer Patients Receiving Combined Thoracic Radiotherapy and Immunotherapy April 19, 2024 Lung Cancer Curative Radiotherapy Immunotherapy 125 University of Missouri - Ellis Fischel Cancer Center Rutgers Cancer Institute of New Jersey University of Rochester Medical Center Columbia New Brunswick Rochester Missouri New Jersey New York 65212 08901 14642 United States United States United States NCT06410287 University of Michigan Testing an Arts-based Program to Reduce Nurse Stigma Towards Perinatal Substance Use June 2024 Nurse's Role Stigma, Social Implicit Bias ArtSpective 150 NCT06410274 University of Leicester Ischaemic Lesions in Acute Intracerebral Haemorrhage May 1, 2024 Intracerebral Haemorrhage Stroke Cerebral Autoregulation Cerebral Blood Flow Transcranial Doppler Magnetic Resonance Imaging Transcranial Doppler ultrasonography (TCD) 120 NCT06410261 University of Illinois at Chicago Exercise Rehabilitation Program in MS Who Use Wheelchairs as a Primary Mobility Device July 1, 2024 Multiple Sclerosis Exercise Rehabilitation Physical function Cognition Exercise rehabilitation program 24 NCT06410248 Northwestern University Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma July 12, 2024 Recurrent Glioblastoma, IDH-Wildtype Recurrent WHO Grade 2 Glioma Recurrent WHO Grade 3 Glioma Recurrent WHO Grade 4 Glioma Biospecimen Collection Magnetic Resonance Imaging Questionnaire Administration Resection Temozolomide Triapine 30 Northwestern University Chicago Illinois 60611 United States NCT06410235 Istanbul Medipol University Hospital The Effect of Thoracic Manipulation on Upper Body Stability in Basketball Athletes April 17, 2024 Athletic Injuries Thoracic manipulation and exercise program exercise program 60 Bahçehir University Istanbul Turkey NCT06410222 Tongji Hospital Predictive Models for the Treatment of Recurrent Herpes Zoster Neuralgia Following Spinal Cord Electrical Stimulation. March 1, 2024 Post Herpetic Neuralgia Herpes zoster post-herpes zoster spinal cord stimulation Recurrence after undergo spinal cord stimulation 300 Tongji Hospital Wuhan Hubei 430030 China NCT06410209 Children's Oncology Group A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study October 21, 2024 Hematopoietic and Lymphatic System Neoplasm Malignant Solid Neoplasm Goal Setting Interview Interview Media Intervention Medical Device Usage and Evaluation Medical Device Usage and Evaluation Questionnaire Administration Reward Text Message-Based Navigation Intervention Text Message-Based Navigation Intervention 190 NCT06410196 Laureate Institute for Brain Research, Inc. Mood and Decision-making in Methamphetamine Use Disorder July 2024 Methamphetamine Abuse Mood modulation 80 Laureate Institute for Brain Research Tulsa Oklahoma 74136 United States NCT06410183 Rijnstate Hospital Inter-rater Reliability of Preoperative Mortality Risk Calculators February 1, 2019 Reliability preoperative high-risk patient no intervention 34 Rijnstate Hospital Arnhem Gelderland 6800 TA Netherlands NCT06410170 Ottawa Fertility Centre Correlation of Urinary and Serum Hormone Levels in Natural Cycle Frozen Embryo Transfer Cycles May 2024 Fertility Issues Mira device Fertility tracking At home use MIRA Device 100 Olive Fertility Centre Vancouver British Columbia V5Z 3X7 Canada NCT06410157 University of Southern California Heartrate and Breathing Effects on Attention and Memory July 2024 Age-related Cognitive Decline Alzheimer Disease Daily practice 240 NCT06410144 University of Rochester Outcomes of a Palliative Care Intervention to Improve Kidney Therapy Decision-Making for Older People With Advanced Chronic Kidney Disease (CKD) May 2024 Chronic Kidney Diseases CKD-EDU Usual Care 326 University of Rochester Medical Center Rochester New York 14642 United States NCT06410131 Sound Biopharmaceuticals Ltd. Study in Patients With Advanced Solid Tumors to Evaluate the Safety of FTL008.16 June 2024 Solid Tumors Solid Tumors Sound Biopharmaceuticals FTL008.16 FTL008.16 68 Cancer Institute and Hospital, Chinese Academy of Medical Sciences Beijing Beijing 100021 China NCT06410118 Tel Aviv University The DreamChanger Intervention in Combination With Imagery Rehearsal Therapy for Children's Nightmares May 2024 Nightmare DreamChanger+IRT 120 Tel Aviv University Tel Aviv Israel NCT06410105 Tishreen University Orthodontic Treatment With Clear Aligner December 19, 2020 Orthodontic Pathological Resorption of External Root Orthodontic, clear aligners, fixed appliances, CBCT CLEAR ALIGNERS 26 Tishreen University Latakia Syrian Arab Republic NCT06410092 Sound Biopharmaceuticals Ltd. Study in Patients With Advanced Solid Malignancies to Evaluate the Safety of FTL001 June 5, 2023 Solid Tumor Solid Tumor FTL001 Sound Biopharmaceuticals FTL001 44 Cancer Institute and Hospital, Chinese Academy of Medical Sciences Chongqing University Cancer Hospital West China Hospital Beijing Chongqing Chengdu Beijing Chongqing Sichuan 100021 400030 610041 China China China NCT06410079 Société Française de chirurgie de la Hanche et du Genou Difference in Return to Sports Activity After Hip Arthroplasty by THR or Resurfacing June 1, 2024 Hip Arthrosis Femur Head Necrosis total hip replacement 500 Santé Atlantique Saint Herblain Nantes 44800 France NCT06410066 Soroka University Medical Center Outcomes of Critically Ill Patients With Hematologic Malignancies January 1, 2009 Hematologic Malignancy intensive care unit haematologic malignancy mortality no intervention 144 NCT06410053 University College Dublin The All Ireland Infectious Diseases Cohort Project March 2011 Infectious Disease Human Immunodeficiency virus COVID-19 Viral hepatitis Skin and soft tissue infections Bone infection 10000 Cork University Hospital Our Lady of Lourdes Hospital, Drogheda St Vincent's University Hospital, Ireland Mater Misericordiae University Hospital Beaumont Hospital Children's Health Ireland at Crumlin St James's Hospital St Luke's General Hospital, Kilkenny Wexford General Hospital Cork Drogheda Dublin Dublin Dublin Dublin Dublin Kilkenny Wexford D4 Dublin 7 Ireland Ireland Ireland Ireland Ireland Ireland Ireland Ireland Ireland NCT06410040 Sichuan Cancer Hospital and Research Institute A Retrospective Study of the Efficacy and Safety of Lolatinib in ALK+ NSCLC Patients With Brain or Meningeal Metastasis August 20, 2023 ALK-positive Non-small Cell Lung Cancer Brain Metastases Meningeal Metastasis Lorlatinib 28 Sichuan cancer hospital Chengdu Sichuan 610000 China NCT06410027 Universidad de Granada Effects of Pain Neuroscience Education and Virtual Reality in Patients With Chronic Low Back Pain May 8, 2024 Chronic Low-back Pain Pain Neuroscience Education + Virtual Reality + Therapeutic Exercise Therapeutic Exercise 40 University of Granada Granada Spain NCT06410014 University Hospital Bispebjerg and Frederiksberg Assessment of Overall Functioning in Patients With Complex Health Issues October 10, 2023 Activities of Daily Living Surveys and Questionnaires ADL Motor Skills Disability Evaluation Health Status Muscle Strength Physical Examination No intervention is performed 100 Afdeling for Socialmedicin Frederiksberg 2000 Denmark NCT06410001 University of Minnesota CE-STAND: Cervical Epidural STimulation After Neurologic Damage June 1, 2024 Cervical Spinal Cord Injury Epidural Spinal Cord Stimulation (eSCS) 36 NCT06409988 Germans Trias i Pujol Hospital Safe Discharge in Lower Gastrointestinal Bleeding June 1, 2014 Lower GI Bleeding Discharge lower gastrointestinal bleeding Oakland score SHA2PE score Safe discharge 398 Hospital Universitari Germans Trias i Pujol Badalona 08916 Spain NCT06409975 University of Rhode Island Feasibility and Acceptability of Mindful Self-Compassion Among Transgender and Nonbinary Young Adults October 2024 Healthy transgender nonbinary mindful self-compassion feasibility acceptability Mindful Self-Compassion (MSC) 50 NCT06409962 Universidad de Córdoba A New Technological Intervention to Address Childhood Obesity: May 1, 2024 Body Weight Dyslipidemias Musculoskeletal Diseases pediatric body mass index intervention anthopometric blood pressure Technological combination 215 NCT06409949 University of Nebraska MitoQ Treatment of Claudication: Myofiber and Micro-vessel Pathology June 1, 2023 Peripheral Arterial Disease Walking assessment QOL Survey Ankle pressure at rest and after stress Muscle Oxygen Serum MitoQ Level Needle Biopsy 60 VA Medical Center Omaha Nebraska 68105 United States NCT06409936 Gruppo Italiano Malattie EMatologiche dell'Adulto PEARL Study: PotEntial of Asciminib in the eaRly Treatment of CML September 2024 CML, Chronic Phase Chronic Myeloid Leukemia, Chronic Phase Chronic Myeloid Leukemia, BCR/ABL-Positive Chronic Myeloid Leukemia asciminib nilotinib Asciminib Nilotinib 160 NCT06409923 Université Libre de Bruxelles Comparison of Skeletal Effects of Herbst and Invisalign MA in Growing Patients With KLass II Malocclusion February 14, 2024 Mandibular Growth Stimulation Stimulation of mandibular growth. 30 Université LIbre de Bruxelles UNiversité Libre de Bruxelles Anderlecht Brussels 1070 1070 Belgium Belgium NCT06409910 University Health Network, Toronto Adaptive Moderately Hypofractionated Post Operative Radiotherapy June 2024 Post-Operative Prostate Cancer Radiotherapy 204 NCT06409897 University of Sao Paulo General Hospital Respiratory Mechanics Assessment at Different Head of the Bed Elevations in Mechanically Ventilated Patients October 15, 2023 Respiratory Failure Pulmonary Disease Respiratory Failure Pulmonary disease Intensive care Respiratory Mechanics Sequencial increasing of head of the bed elevation and alveolar recruitment maneuver followed by a PEEP titration with 10° of head of the elevation 40 Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da USP São Paulo 05403-900 Brazil NCT06409884 University Hospital, Antwerp Diagnosing Drug Allergy: the T is the Key May 25, 2024 Amoxicillin Allergy Amoxicillin Amoxicillin Allergy Allergy T-cells T-cell activation test using intracellular markers 300 NCT06409871 Universidad de Granada Impact of Methylxanthine Intake and Blue Light Exposure on Adhesive Shoulder Capsulitis. May 15, 2024 Adhesive Capsulitis of Shoulder Adhesive Shoulder Capsulitis Metabolic Profile Inflammation Mediators Insomnia Disorders Biological Rhythms Physiotherapy treatment. Physiotherapy treatment and modification of the biorhythm. 34 Hospital Reina Sofía de Córdoba Córdoba Spain NCT06409858 University of the Fraser Valley Efficacy Testing of Les Mills Pilates May 2024 Core Muscle Endurance Pilates 25 NCT06409845 University of Florence Effectiveness and Tolerability of Eptinezumab March 26, 2024 Migraine Migraine With Aura Migraine Without Aura Chronic Migraine Headache Medication overuse headache Pain Migraine prevention Anti-CGRP monoclonal antibodies eptinezumab Eptinezumab 100 or 300 mg ev 100 SOD Centro Cefalee e Farmacologia Clinica, AOU Careggi AOU Policlinico Di Modena Florence Modena 50134 41124 Italy Italy NCT06409832 University of Florence RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatment March 26, 2024 Migraine Migraine With Aura Migraine Without Aura Chronic Migraine Headache Medication overuse headache Pain Migraine prevention Gepant Rimegepant Rimegepant 75 mg 100 SOD Centro Cefalee e Farmacologia Clinica, AOU Careggi IRCCS National Neurological Institute "C. Mondino" Foundation Florence Pavia 50134 27100 Italy Italy NCT06409819 University of California, San Diego Phage Therapy for Recurrent UTIs in Kidney Transplant Recipients June 1, 2024 Urinary Tract Infection, Recurrent phage therapy control 32 NCT06409806 University College, London Electrocorticographic Monitoring of Brain Retraction Injury (EMBRI) August 1, 2022 Brain Injury Neurosurgery Brain Ischemia Brain retraction ECOG Array 6 National Hospital Neurology and Neurosurgery London Greater London WC1N 3BG United Kingdom NCT06409793 University of British Columbia Motivating Adolescent Fitness June 1, 2024 Exercise Training mHealth 120 University of British Columbia Kelowna British Columbia V1V 1V7 Canada NCT06409780 University of Bari Comparative Efficacy of CUS, CXR and CAD in TB Diagnosis in LMIC May 5, 2024 Tuberculosis, Pulmonary Tuberculosis Chest Ultrasound Chest X-Ray CAD LMIC Comparative analysis of CUS, CAD and CXR in pulmonary TB 136 NCT06409767 University Hospital, Angers Impact of an Early Warning System on the Prognosis of Patients With Hematological Malignancies Receiving Intensive Chemotherapy With or Without Hematopoietic Cell Transplantation, a Multicenter Cluster Randomized Study October 15, 2024 Leukemia, Lymphoma, Multiple Myeloma Intensive chemotherapy hematopoietic cell transplantation early ICU admission Real-time calculation of the NEWS with ICU admission if NEWS ≥ 7. 2224 Centre Hospitalier Amiens-Picardie Centre Hospitalier Universitaire d'Angers Centre Hospitalier Universitaire Besancon Centre Hospitalier Universitaire Brest Centre Hospitalier universitaire Nancy Centre Hospitalier Universitaire Nantes Centre Hospitalier Universitaire poitiers centre Hospitalier Universitaire Rennes centre Hospitalier Universitaire Saint etienne centre Hospitalier Universitaire Tours Amiens Angers Besançon Brest Nancy Nantes Poitiers Rennes Saint-Étienne Tours 80054 49933 25030 29609 45011 44093 86021 35033 42270 37044 France France France France France France France France France France NCT06409754 Instituto Nacional de Rehabilitacion BCI-FES for Upper Limb Rehabilitation in Chronic Stroke June 2024 Stroke Upper Extremity Paresis Neuronal Plasticity Stroke Upper Extremity Paresis Neurorehabilitation Brain-Computer Interfaces Functional Electrical Stimulation Neuronal Plasticity Magnetic Resonance Imaging Functional Electrical Stimulation Therapy coupled to a P-300 based Brain-Computer Interface Conventional Physical and Occupational Therapy 33 Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra México City Cdmx 14389 Mexico NCT06409741 Hospital General Universitario de Alicante PrEveNtion of Biliary Events After Acute Pancreatitis In NonSUrgicaL pAtients: PENINSULA Trial July 2024 Acute Pancreatitis Due to Gallstones Acute Pancreatitis sphincterotomy acute pancreatitis recurrence conservative treatment biliopancreatic events Biliary sphincterotomy 126 Hospital Universitaria Reina Sofía Hospital General Universitario Dr. Balmis Hospital Universitario Ramón y Cajal Hospital Clinico Universitairo Hospital Universitario Río Hortega Córdoba Alicante Madrid Valencia Valladolid Cordoba 03010 Spain Spain Spain Spain Spain NCT06409728 University Hospital, Montpellier Prevalence and Healthcare Consumption of ASD Patients Using French Medico-administrative Data June 1, 2024 Autism Spectrum Disorder Administrative claims Population surveillance 600 University Hospital Dijon University Hospital Montpellier Dijon Montpellier 34295 France France NCT06409715 Gansu University of Chinese Medicine Addressing Kinesiophobia in Post-Meniscoplasty Patients Through Progressive Muscle Relaxation Training and Acupressure November 1, 2021 Meniscus Tear Enhanced Care with PMRT and Acupressure standard care 65 Chengguanqu Lanzhou Gansu 730000 China NCT06409702 The First Affiliated Hospital of Soochow University Treatment of High-risk Newly Diagnosed Multiple Myeloma With Minimal Residual Disease Detection May 2024 Newly Diagnosed High Risk MRD Multiple Myeloma Carfilzomib Daratumumab Lenalidomide Dexamethasone VRD for first-cycle induction therapy 45 NCT06409689 Tongji Hospital Oliceridine-Enhanced Analgesia and Recovery: A G-Protein Biased μ-Opioid Study May 1, 2024 Postoperative Analgesia Oliceridine fumarate low dose Oliceridine fumarate high dose Oliceridine fumarate moderate dose morphine 80 NCT06409676 Istituto Clinico Humanitas Applicability of Enhanced Recovery After Surgery Protocols in the Therapeutic Endoscopy Suite June 1, 2024 Colorectal Endoscopic Submucosal Dissection ERAS protocols 220 Humanitas Research Hospital Milano 20089 Italy NCT06409663 Novavax Phase 3 Strain Change Study for SARS-CoV-2 rS Vaccines August 5, 2024 Severe Acute Respiratory Syndrome Coronavirus 2 Infection coronavirus 2 (SARS-CoV-2) NVX-CoV2705 Vaccine 100 NCT06409650 Suzhou Kintor Pharmaceutical Inc, To Evaluate Safety and Efficacy of KX-826 in Chinese Female Subjects With Androgenetic Alopecia November 9, 2021 Alopecia Androgenetic Alopecia Hair loss Female pattern hair loss KX-826 160 Beijing Friendship Hospital, Capital Medical University Beijing Tongren Hospital, Capital Medical University China-Japan Friendship Hospital Peking University First Hospital Peking University People's Hospital Xiangya Hospital Central South University The First Affiliated Hospital of Chongqing Medical University Dermatology Hospital of Southern Medical University Sir Run Run Shaw Hospital of Zhejiang University School of Medicine The First Affiliated Hospital, Zhejiang University School of Medicine Huashan Hospital, Fudan University Shenzhen People's Hospital The First Hospital of Hebei Medical University Suining Central Hospital The Second Affiliated Hospital of Xi'an Jiaotong University Beijing Beijing Beijing Beijing Beijing Changsha Chongqing Guangzhou Hangzhou Hangzhou Shanghai Shenzhen Shijiazhuang Suining Xi'an China China China China China China China China China China China China China China China NCT06409637 Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University FOLFOX Plus Lenvatinib Adjuvant Therapy for Hepatocellular Carcinoma Post-Liver Transplantation January 1, 2025 Liver Cancer Liver Transplant FOLFOX4 regimen lenvatinib 62 Organ Transplantation Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou Guangdong 376032 China NCT06409624 University of Giessen Association Between Biomarkers and eGFR Decline in Pulmonary Hypertension May 2024 Pulmonary Hypertension No intervention is planned as part of the study 200 University Hospital Giessen and Marburg, Campus Giessen, Department of Internal Medicine II Giessen Hessen 35392 Germany NCT06409611 Universidade Federal do Rio de Janeiro MUSCLE EFFECTS OF NEUROMUSCULAR ELECTROSTIMULATION IN MECHANICALLY VENTILATED PATIENTS IN AN ICU May 1, 2024 Intensive Care Unit Acquired Weakness neuromuscular electrical stimulation Intensive Care Unit Acquired Weakness neuromuscular electrical stimulation 22 Pedro Ernesto University Hospital Rio De Janeiro 20551-030 Brazil NCT06409598 University of Exeter NOVEL Program for Stroke Telerehabilitation May 2024 Chronic Stroke virtual reality Telerehabilitation Qualitative Feasibility Non-immersive virtual reality home-based exercise. 30 University of Exeter Exeter EX1 2LU United Kingdom NCT06409585 University of Edinburgh Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition May 1, 2023 Heart Failure With Preserved Ejection Fraction Hypertrophic Cardiomyopathy Cardiac Sarcoidosis Hypertensive Heart Disease Tako Tsubo Cardiomyopathy Arrhythmogenic Right Ventricular Cardiomyopathy 1 Myocarditis 68Ga-FAPI or 18F-AlF-FAPI cardiac PET-MR Echocardiogram Cardiac MRI 290 University of Edinburgh Edinburgh Scotland EH16 5RR United Kingdom NCT06409572 Sohag University Study of GeneXpert Mycobacterium Tuberculosis/ Rifampicin (MTB/RIF) Versus the Routine Methods for Detection of Mycobacterium Tuberculosis June 2024 Tuberculosis GeneXpert MTB/RIF 80 NCT06409559 University of Cincinnati Rim Plate to Buttress Plate for Posterior Wall Acetabular Fractures With and Without Inter-fragmentary Screws August 1, 2023 Acetabular Fracture pelvic reconstruction 60 University of Cincinnati College of Medicine Cincinnati Ohio 45267 United States NCT06409546 University of Catania Impact of Topical Pentoxifylline and Tocopherol in Treatment and Prevention of Medically-related Osteonecrosis of the Jaws April 2, 2020 Medically Related Osteonecrosis of the Jaws Tocopherol and pentoxifilline topical gel Placebo 48 AOU Policlinico G. Rodolico Catania CT 95124 Italy NCT06409533 University of Brawijaya Rate Control Efficacy in Atrial Fibrillation With Rheumatic Mitral Stenosis: Lenient vs Strict Rate Control Strategies March 1, 2023 Atrial Fibrillation Rheumatic Mitral Stenosis Arrhythmias, Cardiac Atrial Fibrillation Mitral Stenosis Rheumatic Heart Disease Heart Rate Control Rate Control Rate control 100 Saiful Anwar Hospital Prima Husada Sukorejo Hospital Dr. Iskak Regional General Hospital Malang Pasuruan Tulung Agung East Java East Java East Java 65111 67161 66223 Indonesia Indonesia Indonesia NCT06409520 Sohag University Impact Of Subclinical Hypothyroidism On Short-Term Outcomes In Patients With Acute Coronary Syndrome In Sohag University Hospitals April 25, 2024 Subclinical hypothyroïdism Acute Coronary Syndrome thyroid function tests cardiac enzymes ECG 200 Sohag university Hospital Sohag Sohag Egypt NCT06409507 First People's Hospital of Hangzhou Research and Application for New Clinical Diagnosis and Treatment System for HBV Related HCC Liver Transplantation January 1, 2015 Hepatocellular Carcinoma Liver Transplantation Prognosis FKBP12 expression 178 NCT06409494 EuBiologics Co.,Ltd Clinical Trial to Evaluate EuHZV in Healthy Adults Aged 50 to 69 Years June 17, 2024 Varicella Zoster Virus Infection Herpes Zoster EuHZV HZV Varicella Zoster Virus Herpes Zoster EuHZV Shingrix 72 NCT06409481 The First Affiliated Hospital of Xinxiang Medical College Pharmacovigilance Assessment of Reporting of Cardiovascular Adverse Events With Antineoplastic Agents (PARCA) June 1, 2024 Cardiovascular Diseases Cardiac Diseases Vascular Diseases Cancer Antineoplastic Agents 800000 NCT06409468 Semmelweis University NovoMatrix in Gingival Recession Coverage: Case Series May 5, 2024 Gingival Recession, Generalized Subperiostal tunnel in conjunction with Novomatrix 20 Semmelweis University, Faculty of Dentistry Budapest 1088 Hungary NCT06409455 Education University of Hong Kong Positive Dementia Caregiving: Clinical Trial of an Online Training Program August 2024 Caregiver Stress Syndrome Family caregiving Positive Dementia Caregiving in 30 Days 200 NCT06409442 Dokuz Eylul University Effects of Corrective External Support and Regional Vibration Applications in Subacromial Pain Syndrome May 15, 2024 Subacromial Pain Syndrome shoulder impingement syndrome pain physical therapy and rehabilitation ultrasonography Standard Physiotherapy Program Kinesio Taping Local Vibration Therapy 63 NCT06409429 Tianjin Medical University Cancer Institute and Hospital Nimotuzumab Combined With GX as Postoperative Adjuvant Therapy in Pancreatic Cancer May 1, 2024 Pancreatic Cancer Nimotuzumab GX Placebo 146 Tianjin Medical University Cancer Institute and Hospital Tianjin China NCT06409416 Casa Sollievo della Sofferenza IRCCS Tumor Cell Plasticity and Aggressiveness in Human Non-small Cell Lung Cancer June 1, 2024 Lung Neoplasms Progression Analysis of diagnostic biomarkers 20 NCT06409403 The Third Xiangya Hospital of Central South University Study on Effect of Robotic Versus Laparoscopic Surgical Technology on Genitourinary Function After Total Mesorectal Excision for Rectal Cancer January 1, 2017 Colorectal Cancer clinical application of robotic technique 164 The Third Xiangya Hospital of Central South University Changsha Hunan 410013 China NCT06409390 H. Lee Moffitt Cancer Center and Research Institute Pilot Study of Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer May 2024 Metastatic Breast Cancer Taxotere Cytoxan Trastuzumab deruxtecan Sacituzumab govitecan Xeloda Fulvestrant Ribociclib Abemaciclib 15 Moffitt Cancer Center Tampa Florida 33612 United States NCT06409377 Theodor Bilharz Research Institute Effect of Dexmedetomidine on Improving Intubating Conditions Without the Use of Muscle Relaxant February 25, 2024 Intubation Muscle Relaxation Dexmedetomidine Dexmedetomidine Intubating conditions No muscle relaxant Precedex 200 MCG in 2 ML Injection C group: 74 Theodor Bilharz research institute Theodor Bilharz research institute Cairo Cairo 020 02 Egypt Egypt NCT06409364 The George Institute FLudrocortisone Administration in Aneurysmal Subarachnoid Haemorrhage July 1, 2024 Aneurysmal Subarachnoid Hemorrhage aSAH Fludrocortisone 524 NCT06409351 Singapore General Hospital Multi-modal Training Program to Promote Physical Activity After Stroke: A Randomised Controlled Trial. May 1, 2024 Stroke Physical Inactivity Physical activity Behavioural change Implementation Science Stroke Intervention group 120 Singapore General Hospital Singapore 169608 Singapore NCT06409338 The First Affiliated Hospital with Nanjing Medical University Research on the Brain Mechanism of taVNS in Regulating PD Motor Symptoms May 2024 Parkinson Disease Parkinson's disease motor symptoms taVNS neural mechanism Transcutaneous auricular vagus nerve stimulation (active） Transcutaneous auricular vagus nerve stimulation (sham） 32 the First Affiliated Hospital of Nanjing Medical University Nanjing Jiang Su 210029 China NCT06409325 Shanghai Mental Health Center Effectiveness of MST Versus ECT for Major Depressive Episode August 1, 2024 Major Depressive Disorder (MDD) Electroconvulsive therapy (ECT) magnetic seizure therapy (MST) MST ECT 150 Shanghai Mental Health Center Shanghai Shanghai 200030 China NCT06409312 Schulthess Klinik Digital Healthcare App After Total Hip Arthroplasty May 21, 2024 Unilateral Initial Implantation of a Minimally-invasive Hip Endoprosthesis Akina Cloud 20 NCT06409299 Rigshospitalet, Denmark Enhancing Lung Health in Kids With Structural Lung Damage and Malformations: Azithromycin (AZI) for Airway Infection Prevention September 1, 2024 Tracheomalacia Bronchopulmonary Dysplasia (BPD) Vascular Ring Cystic Lung Disease Bronchiectasis Chronic Atelectasis Azithromycin 40 MG/ML Placebo 150 NCT06409286 Rhaeos, Inc. Assessment of Flow in Cerebrospinal Fluid Shunts With a Second Generation Wireless Thermal Anisotropy Measurement Device May 2024 Hydrocephalus Thermal Anisotropy Measurement Device 17 NCT06409273 Research on Healthcare Performance Lab U1290 Hybrid Course Assessment and Evaluation May 14, 2024 Education, Medical Medical education Students dissertations, academic Evaluation studies Educational measurement Hybrid course on medical thesis for post graduates general practice students Face-to-face teaching on medical thesis for post graduates general practice students 170 NCT06409260 Rigshospitalet, Denmark Neuromuscular Monitoring in Children (6 Months - 2 Years) With Electromyography and Acceleromyography June 1, 2024 Neuromuscular Blockade Acceleromyography (AMG) Electromyography (EMG) 120 Rigshospitalet Copenhagen 2100 Denmark NCT06409247 Palo Alto University iExposure Intervention for Social Anxiety June 1, 2024 Social Anxiety iExposure iExposure plus attention guidance iExposure plus attention control 390 NCT06409234 European Society of Anaesthesiology Perioperative Management & Outcome Following Preoperative Transthoracic Echocardiography in Noncardiac Surgery Patients June 30, 2024 Elective Surgical Procedure transthoracic echocardiography Transthoracic Echocardiography Recieved 8250 University Hospital Düsseldorf Düsseldorf 40225 Germany NCT06409221 Concr VISION: Triple Negative Breast Cancer Sample and Clinical Data Acquisition Study May 1, 2024 Cancer, Breast Triple Negative Breast Cancer Early-stage Breast Cancer Non-interventional study, Observational only 200 Royal Marsden Hospital London United Kingdom NCT06409208 Dhulikhel Hospital Use of mHealth Intervention in Improving Utilization of Postpartum Care May 2024 Postnatal Care mHealth Intervention mHealth intervention (video and reminder SMSs) 300 Dhulikhel Hospital Dhulikhel Bagmati 45210 Nepal NCT06409195 DermBiont, Inc. A Trial to Study the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Seborrheic Keratoses and Non-Melanoma Skin Cancers March 25, 2024 Non-Melanoma Skin Cancers SM-020 1% Gel 50 Dermatology, Laser and Vein Specialist Charlotte North Carolina 28207 United States NCT06409182 Chinese University of Hong Kong A Prospective Pilot Study to Evaluate the Diagnostic Performance of a Wireless Sensor Capsule in Detection of UGIB December 19, 2023 UGI Bleed Hemopill 30 Prince of Wales Hospital Hong Kong Hong Kong NCT06409169 Oregon Health and Science University DBS TaT in Peer-assisted Telemedicine for Hepatitis C May 2024 Hepatitis C Hepatitis C Substance Use DBS TaT Usual Care 183 NCT06409156 The Cleveland Clinic EOIFP Block Versus OSTAP Block for Upper Abdominal Surgery May 24, 2024 Open Abdominal Surgery Abdominal Block Oblique Subcostal Transversus Abdominis Plane Block External Oblique Intercostal Fascial Plane block 100 Cleveland Clinic Foundation Cleveland Ohio 44195 United States NCT06409143 National Taiwan University Hospital High-definition Transcranial Electrical Stimulation for Upper Extremity Rehabilitation June 1, 2024 Stroke Stroke High-Definition Transcranial Electrical Stimulation Upper-limb rehabilitation Transcranial electrical stimulation Neuroplasticity HD-tES Sham HD-tES UE rehabilitation HD-tES (Bilateral) 152 New Taipei City Tucheng Hospital National Taiwan University Hospital Taipei Medical University Hospital New Taipei City Taipei Taipei Taiwan Taiwan Taiwan NCT06409130 Novo Nordisk A/S Effects of NNC0194-0499, Cagrilintide, and Semaglutide Alone or in Combinations on Liver Damage and Alcohol Use in People With Alcohol-related Liver Disease May 20, 2024 Alcohol-related Liver Disease NNC0194-0499 Semaglutide NNC0194-0499 placebo Semaglutide placebo (Group A) Cagrilintide + semaglutide Cagrilintide Cagrilintide placebo Semaglutide placebo (Group B) 240 The Institute for Liver Health Arizona Liver Center Del Sol Research Management, LLC OM Research LLC California Liver Research Institute Miguel Rebollar PA UF Hepatology Jacksonville Univ of Miami/Schiff Ctr Covenant Metabolic Specialists LLC Rush University Med. Cntr Kansas Medical Clinic, PA Louisiana Research Center, LLC Boston Medical Center_Cary Mayo Clinic Rochester Jubilee Clinical Research, Inc. University of Pennsylvania Hospital UPMC_Center for Liver Care Digestive Health Research, TN Texas Clinical Research Institute The Liver Institute Liver Specialists of Texas Houston Research Institute Amer. Rrsch Corp-TX Liver Inst Velocity Clinical Res, Waco Holdsworth House Clinical Research Nepean Hospital St George Hospital Westmead Hospital Eastern Clinical Research Unit Box Hill St Vincent's Hospital (Melbourne) Austin Health Fiona Stanley Hospital - Hepatology Multiprofile Hospital For Active Treatment St. Ivan Rilski Gorna Oriahovitsa EOOD "Acibadem City Clinic MHAT Tokuda" UMHAT "Sv. Ivan Rilski", Clinic of Gastroenterology UMHAT Aleksandrovska "DCC XX - Sofia" EOOD Medical Center Synexus Sofia University of Calgary Liver Unit-(HMRC) GI Research Institute London Health Sciences Centre- University Hospital TDDA Specialty Research Ctr de Med Metab de Lanaudiere Krajská nemocice Liberec, a.s Vseobecna Fakultni nemocnice v Praze Aalborg Universitetshospital Herlev Hospital Hvidovre Hospital Odense University Hospital Centre Hospitalier Universitaire D'Angers-1 Centre Hospitalier Universitaire de Lille-Hopital Claude Huriez Groupe Hospitalier Mutualiste Des Portes Du Sud Universitätsklinikum des Saarlandes - Klinik für Innere Medizin II Prof. Dr. Schiefke Ingolf, EUGASTRO GmbH Universitätsklinikum Leipzig, Klinik und Poliklinik Universitätsklinikum Schleswig-Holstein Universitätsmedizin der Johannes-Gutenberg-Universität Mainz Universitätsklinikum Münster - Medizinische Klinik B Universitätsklinikum Würzburg, ZIM "Laiko" General Hospital of Athens University Hospital of Athens ATTIKON 'Ippokrateio' General Hospital of Thessaloniki 'Ippokrateio' General Hospital of Thessaloniki AOU Careggi Firenze IRCCS Azienda Ospedaliero Universitaria San Martino - IST Ospedale Evangelico Betania Azienda Ospedaliera di Padova Fondazione Policlinico Universitario Agostino Gemelli IRCCS Kumamoto Shinto General Hospital Toranomon Hospital, Hepatology Oita Cardiovascular Hospital Japan Community Health care Organization Hokkaido Hospital Albert Schweitzer Ziekenhuis locatie Dordwijk Erasmus MC ETZ Elisabeth Universitair Medisch Centrum Utrecht Centrum Medyczne Intercor Sp. z o.o. Gastromed Sp. z o.o. ID Clinic Arkadiusz Pisula PANSTWOWY INSTYTUT MEDYCZNY MSWiA Samodzielny Publiczny Zaklad Opieki Zdrowotnej Uniwersytecki Szpital w Krakowie Uniwersytecki Szpital Kliniczny w Bialymstoku Sonomed Sp. Z O.O. "LANDA" Katarzyna Agata Landa Hospital Clínico Universitario de Valladolid Hospital Vall d'Hebron Hospital Clinic i Provincial Complejo Hospitalario de Pontevedra - Hospital de Montecelo Hospital Universitario Marqués de Valdecilla Chandler Tucson Tucson Lancaster Pasadena Hialeah Jacksonville Miami Sarasota Chicago Topeka Shreveport Boston Rochester Las Vegas Philadelphia Pittsburgh Hermitage Arlington Dallas Houston Houston San Antonio Waco Darlinghurst Kingswood Kogarah Westmead Box Hill Fitzroy Heidelberg Murdoch Gorna Oryahovitsa Sofia Sofia Sofia Sofia Sofia Calgary Vancouver London Vaughan Terrebonne Liberec Prague 2 Aalborg Herlev Hvidovre Odense C Angers Lille Venissieux Homburg Leipzig Leipzig Lübeck Mainz Münster Würzburg Goudi/Athens Haidari-Athens Thessaloniki Thessaloniki Firenze Genova Naples Padova Roma Kumamoto-shi, Kumamoto Minato-ku, Tokyo Oita-shi, Oita Sapporo-shi, Hokkaido Dordrecht Rotterdam Tilburg Utrecht Bydgoszcz Toruń Mysłowice Warszawa Kraków Białystok Szczecin Kraków Valladolid Barcelona Barcelona Pontevedra Santander Arizona Arizona Arizona California California Florida Florida Florida Florida Illinois Kansas Louisiana Massachusetts Minnesota Nevada Pennsylvania Pennsylvania Tennessee Texas Texas Texas Texas Texas Texas New South Wales New South Wales New South Wales New South Wales Victoria Victoria Victoria Western Australia Alberta British Columbia Ontario Ontario Quebec Kujawsko-Pomorskie Kujawsko-pomorskie Malopolskie Mazowieckie Małopolskie Podlaskie Zachodniopomorskie España 85224 85712 85715 93534 91105 33012 32224 33136 34240 60612 66606 71105 02118 55902 89106 19104 15213 37076 76012 75203 77030 77079 78215 76710 2010 2747 2217 2145 3128 3065 3084 6150 5100 1407 1431 1431 1618 1784 T2N 4Z6 V6Z 2K5 N6A5A5 L4L 4Y7 J6X 4P7 460 01 128 08 9000 2730 2650 5000 49100 59000 69200 66421 04103 04103 23562 55131 48149 97080 11527 GR-12462 54642 GR 54642 50134 16132 80147 35128 00168 862-8655 105-8470 870-0837 062-8618 3318 AT 3015 GD 5022 GC 3584 CX 85-605 87-100 41-400 02-507 30-688 15-540 71-685 31-156 47003 08035 08036 36004 39008 United States United States United States United States United States United States United States United States United States United States United States United States United States United States United States United States United States United States United States United States United States United States United States United States Australia Australia Australia Australia Australia Australia Australia Australia Bulgaria Bulgaria Bulgaria Bulgaria Bulgaria Bulgaria Canada Canada Canada Canada Canada Czechia Czechia Denmark Denmark Denmark Denmark France France France Germany Germany Germany Germany Germany Germany Germany Greece Greece Greece Greece Italy Italy Italy Italy Italy Japan Japan Japan Japan Netherlands Netherlands Netherlands Netherlands Poland Poland Poland Poland Poland Poland Poland Poland Spain Spain Spain Spain Spain NCT06409117 National and Kapodistrian University of Athens 3rd Generation Resorbable Magnesium Scaffolds vs Biodegradable Polymer Stents in NSTE/ACS October 1, 2024 Acute Coronary Syndrome Coronary Artery Disease PCI NSTE/ACS resorbable magnesium scaffolds Scaffolds Percutaneous coronary intervention 220 CHU Saint-Pierre UZ Leuven Hippocration Hospital Brussel Leuven Athens Attiki 1000 3000 11527 Belgium Belgium Greece NCT06409104 National Cancer Institute, Egypt Propofol Versus Dexmedetomidine for Sedation of Cancer Patients Undergoing ERCP September 1, 2023 Sedation in ERCP ERCP Endoscopic cancer sedation propofol Dexmedetomidine Propofol Dexmedetomidine 202 Ahmed Mohamed Soliman Giza Egypt NCT06409091 The Cleveland Clinic Short Term Outcomes of Heavy-weight Versus Medium-weight Synthetic Mesh January 1, 2012 Hernia, Ventral Hernia Incisional Medium weight or Heavy weight mesh 1496 Cleveland Clinic Cleveland Ohio 44195 United States NCT06409078 The First Affiliated Hospital of Soochow University Repeated Transcranial Magnetic Stimulation Relieve Chronic Visceral Pain in IBS April 1, 2024 Irritable Bowel Syndrome Repetitive Transcranial Magnetic Stimulation Chronic Visceral Pain Functional Magnetic Resonance Imaging repeated transcranial magnetic stimulation treatment group Western medicine group 200 The First Affiliated Hospital of Soochow University Suzhou Jiangsu 215006 China NCT06409065 M.D. Anderson Cancer Center Psycho-Spiritual Management for Patients With Advanced Cancer and Their Family Caregivers January 9, 2024 Cancer Meditation Program 400 MD Anderson Houston Texas 77030 United States NCT06409052 M.D. Anderson Cancer Center Endometrial Cancer, Risk Factors and Prevention Strategies: Perspectives of Patients and At-Risk Women August 30, 2024 Endometrial Cancer Qualitative interviews 45 MD Anderson Cancer Center Houston Texas 77030 United States NCT06409039 Azienda Ulss 2 Marca Trevigiana POLE-END REAL LIFE: Endometrial Cancer Early Stages I-II and Advanced Stages III and IV Evaluation of POLE as a Prognostic Factor. Participants Are Women >= 18 Years Old, With the Pole Mutation September 4, 2023 Endometrial Neoplasms 80 Aulss2 Marca Trevigiana Ospedale Ca Foncello Aulss2 Marca Trevigiana Ospedale Ca Foncello Treviso Treviso TV Veneto 31100 31100 Italy Italy NCT06409026 Mayo Clinic Sotatercept on Central Cardiopulmonary Performance and Peripheral Oxygen Transport During Exercise in Pulmonary Arterial Hypertension May 2024 Pulmonary Arterial Hypertension Sotatercept 21 Mayo Clinic in Rochester Rochester Minnesota 55905 United States NCT06409013 Mayo Clinic Evaluation of Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography in Patients With Sarcoma March 14, 2024 Bone Sarcoma Soft Tissue Sarcoma Non-Interventional Study 50 Mayo Clinic in Rochester Rochester Minnesota 55905 United States NCT06409000 Mayo Clinic Evaluation of 3D Surface Scanning for Virtual-CT Based Radiation Therapy Treatment Planning January 19, 2021 Hematopoietic and Lymphatic System Neoplasm Malignant Solid Neoplasm Electronic Health Record Review Three-Dimensional Imaging 26 Mayo Clinic in Arizona Scottsdale Arizona 85259 United States NCT06408987 Assiut University Arthroscopically Assisted Versus Open Surgical Reduction of the Hip in Patients With Irreducible DDH Before the Walking Age May 15, 2024 Developmental Dysplasia of the Hip arthroscopically assisted open surgical reduction 32 NCT06408974 Assiut University Comparison Between Ketamine Intrathecal and iv Dexamethasone for Post Cesarean Analgesia December 1, 2024 Post Cesarean Analgesia Ketamine dexamethasone 90 NCT06408961 Massachusetts General Hospital EVOC - EVs in Obesity and Cardiometabolic Disease January 5, 2023 Cardiovascular Diseases Extracellular Vesicles Cardiometabolic Disease Cardiovascular Risk Type II Diabetes 80 Massachusetts General Hospita; Boston Massachusetts 02114-2696 United States NCT06408948 Jiangsu HengRui Medicine Co., Ltd. A Study to Evaluate the Mass Balance of [14C]SHR7280 in Healthy Adult Volunteers May 20, 2024 Assisted Reproduction [14C]SHR7280 8 The First Affiliated Hospital of Suzhou University Suzhou Jiangsu 215008 China NCT06408935 Janssen-Cilag Ltd. Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients April 17, 2024 Crohn's Disease Guselkumab 112 Galilee Medical Center Rabin Medical Center National Taiwan University Hospital Nahariya Petah Tikva Taipei 2210001 49100 10002 Israel Israel Taiwan NCT06408922 Izmir Democracy University Comparison of the Effects of Single Versus Triple Injections of Platelet-Rich Plasma in Patients With Knee Osteoarthritis April 15, 2023 Knee Osteoarthritis prp injection 80 Buca Seyfi Demirsoy Training and Research Hospital Izmir 35000 Turkey NCT06408909 Istanbul University - Cerrahpasa (IUC) Pharmacist Role in Thyroid Disorders March 15, 2022 Hypothyroidism Hyperthyroidism Thyroid Diseases Hypothyroidism Levothyroxine Drug-Related Problem Clinical Pharmacist Medication Adherence Clinical Pharmacist Intervention Group 44 Marmara University Istanbul 34854 Turkey NCT06408896 Istituto Scientifico Italiano Colonna Vertebrale Development and Internal Validation of Predicting Models of Idiopathic Scoliosis Natural History and Treatment Outcomes Through the Use of Artificial Intelligence in a Large Clinical Database April 24, 2024 Scoliosis Idiopathic 9651 ISICO Milan Mi 20141 Italy NCT06408883 Changhai Hospital Effect of Vibration Capsule on Different Subtypes of Functional Constipation June 1, 2024 Clinical Study Chronic Functional Constipation Vibrating Capsule cohort study Chronic Functional Constipation Vibrabot capsule 600 Changhai hospital Shanghai China NCT06408870 Boehringer Ingelheim A Study in Healthy People to Compare How 2 Different Low Dose Formulations of BI 1015550 Are Taken up in the Body June 6, 2024 Healthy BI 1015550 64 NCT06408857 Bill & Melinda Gates Medical Research Institute Study To Evaluate Safety, Tolerability, and Pharmacokinetics of MAM01 in African Population September 2024 Healthy Volunteers Malaria Plasmodium falciparum MAM01 De-Escalation Dose Escalation Perennial Malaria Transmission Antibody Monoclonal Prevention Pediatric Anemia Malnutrition HIV Ague MAM01 300 mg SC MAM01 300 mg IM MAM01 600 mg SC MAM01 2000 mg IM MAM01 150 mg SC MAM01 75 mg SC MAM01 225 mg SC MAM01 150 mg IM MAM01 150 mg IV Placebo IV MAM01 150 mg Placebo IM Placebo SC 264 KEMRI CGRH, Kenya IDRC-Infectious Disease Research Collaboration, IDRC Masafu General Hospital Manjanji Road JCRC-Joint Clinical Research Centre IDRC-Infectious Disease Research Collaboration, IDRC Tororo Hospital Station Road Kisumu Busia Kampala Tororo 40100 10005 749 Kenya Uganda Uganda Uganda NCT06408844 Inonu University Examining the Impact of Behavior Change Intervention October 7, 2023 Physical Inactivity Behavior, Health Health Behavior 5A Model child behaviour change physical activity health promotion Physical activity behavior change program implemented with 5A model 48 Alparslan Ortaokulu Karaman Turkey NCT06408831 Inonu University The Effect of Web-Based Cyber Sexual Violence Training on Cyber Sexual Violence Experience, Sensitivity and Security June 1, 2024 Cyberbullying cyber sexuality web education consultancy Classroom Teaching University Students Intervention Group 200 NCT06408818 Innovation Research & Training Study of an Online Program to Help Parents Talk With Their Tween Children About Health, Gender, Body-Image, and Relationships May 13, 2024 Parenting Parent-Child Relations Communication Preadolescent Health Media Literacy Parent-Child Communication Gender Stereotypes Body-Image Puberty Sexual Health Relationship Health Media Aware Parent - Tween Active Control Resource 600 innovation Research and Training Durham North Carolina 27713 United States NCT06408805 Istituti Clinici Scientifici Maugeri SpA Autonomic Nervous System Profile in Hereditary Angioedema July 12, 2023 Hereditary Angioedema Hereditary angioedema Heart Rate Variability Autonomic Nervous System Rare disease 60 Istituti Clinici Scientifici Maugeri Milan 20138 Italy NCT06408792 Universidad Complutense de Madrid To Evaluate Postoperative Pain and Quality of Life After Taking a Deephethelized Gingival Graft and Covering it With Different Treatments April 2, 2024 Pain, Postoperative Quality of Life Palate; Wound Deepithelized graft and protection technique 33 Clinica Dental Doctores Garcia Ruiz e Iglesias Esquiroz Alcorcón Madrid 28921 Spain NCT06408779 China National Center for Cardiovascular Diseases Study on Surgical Treatment Strategies for Moderate Ischemic Mitral Regurgitation August 1, 2023 Mitral Valve Insufficiency Mitral Valve Annuloplasty Coronary Artery Bypass mitral valve repair 464 Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China NCT06408766 Bandırma Onyedi Eylül University Investigating the Effects of Smartphone Use on the Masseter Muscle May 30, 2024 Smartphone Addiction Masseter Muscle Hypertrophy Masseter Muscle Spasm Smartphone Addiction masseter thenar 120 NCT06408753 The University of Hong Kong Plasma Biomarker in Predicting Response and Toxicity in HCC Patients Treated With Checkpoint Inhibitors With or Without SBRT November 1, 2019 Hepatocellular Carcinoma Non-resectable Stereotactic Body Radiotherapy SBRT immune checkpoint inhibitors sterotatic body radiotherapy 50 Department of Clinical Oncology Hong Kong Hong Kong NCT06408740 Bandırma Onyedi Eylül University Physical Activity Level in Psychosis Patients September 20, 2023 Psychosis Psychosis Social Participation Functioning Quality of Life Physical Activity 157 Bandırma Onyedi Eylül University Balıkesir Turkey NCT06408727 Clene Nanomedicine Intermediate Expanded Access Protocol CNMAu8.EAP04 ALS Amyotrophic Lateral Sclerosis PALS CNM-Au8 NCT06408714 University of New Mexico Nalmefene vs Naloxone for the Treatment of Recurrent Respiratory Depression After Opioid Overdose July 1, 2024 Opioid Overdose Opiate Overdose opioid overdose opiate overdose drug overdose naloxone nalmefene respiratory depression Nalmefene Injection Naloxone Injection 74 University of New Mexico Health Sciences Center Albuquerque New Mexico 87106 United States NCT06408701 University Hospital, Toulouse Modeling Ocular Developmental Diseases From 3D Cultures of Optic Vesicle Organoids Derived From hiPSCs of Patients With Ocular Malformations May 2, 2024 Eye Abnormalities Microphthalmia Anophthalmia Coloboma Aniridia Blood sampling 20 Purpan University Hospital Toulouse 31059 France NCT06408688 University Hospital, Basel, Switzerland Safety and Modulation of Adaptive Immunity by Iscador® Qu Viscum Album Extract in Patients With Advanced, Recurrent or Metastatic Cancers Treated With Immune Checkpoint Inhibitors June 2024 Advanced Solid Tumor Mistletoe Extract Immune checkpoint inhibitors plus Iscador® Qu. Immune Checkpoint Inhibitors 100 Kantosspital Baden AG Universitätsspital Basel Kantonsspital Baselland Tumor- und Brustzentrum Ostschweiz Baden Basel Liestal Saint Gallen 5404 4031 4410 9016 Switzerland Switzerland Switzerland Switzerland NCT06408675 Ankara City Hospital Bilkent Loss of Cervical Lordosis in Fibromyalgia Syndrome March 1, 2018 Fibromyalgia, Cervical Lordosis Fibromyalgia, cervical lordosis Visual Analog Scale (VAS), QOL (36-Item Short Form Survey (SF-36)), and Neck Disability Index (NDI) were used to assess pain, overall quality of life, functional disability respectively. 107 Ankara City Hospital Emine Esra Bilir Ankara Ankara Çankaya Çankaya 06800 06800 Turkey Turkey NCT06408662 Johns Hopkins University Remote Delivery of a Mindfulness-based Intervention for Tics May 2024 Tourette Syndrome Tourette's Disorder Chronic Motor Tic Disorder Chronic Vocal Tic Disorder Persistent Motor Tic Disorder Persistent Vocal Tic Disorder Persistent Tic Disorder Tic Disorders mindfulness-based intervention for tics (MBIT) psychoeducation with relaxation and supportive therapy (PRST) 150 Johns Hopkins University School of Medicine Baltimore Maryland 21287 United States NCT06408649 Alcon Research Post-market Clinical Follow-up Study of Alcon TOTAL30® Contact Lenses (Lehfilcon A) July 2024 Ametropia Myopia Hyperopia Astigmatism Contact lenses Lehfilcon A spherical contact lenses Lehfilcon A toric contact lenses 168 Contact Alcon Call Center for Trial Locations Fort Worth Texas 76134 United States NCT06408636 The Affiliated Hospital of Xuzhou Medical University Prognostic Role of LA Strain in Acute Myocardial Infarction September 2, 2019 Atrial Fibrillation Myocardial Infarction, Acute Stroke Ischemic Mortality cardiac magnetic resonance myocardial infarction atrial fibrillation ischemic stroke Cardiac MRI 780 The Affiliated Hospital of Xuzhou Medical University Xuzhou Jiangsu 221002 China NCT06408623 Cancer Institute and Hospital, Chinese Academy of Medical Sciences Chidamide Combined With Sintilimab and Bevacizumab for the First-line Treatment of Advanced Liver Cancer May 15, 2024 Liver Cancer chidamide combined with Sintilimab and bevacizumab 48 NCT06408610 Cairo University Moderate Continuous Versus High Interval Intensity Training on Gut Dysbiosis and GLP1 Hormone in IBS May 1, 2024 Irritable Bowel Syndrome Obesity Dysbiosis moderate intensity continuous training 5 Faculty of medicine cairo university National Nutrition institute Faculty of physiotherapy cairo university Cairo Cairo Giza Egypt Egypt Egypt NCT06408597 Cairo University Mannitol Versus Nitroglycerin for Kidney Injury Prevention in Robotic-assisted Radical Prostatectomy or Cystectomy May 12, 2024 Prostate Cancer Bladder Cancer Surgery Renal Impairment Renal Injury, Acute Radical Prostatectomy Radical Cystectomy Robotic Anesthesia Mannitol Nitroglycerin Nitroglycerin Infusion Mannitol Infusion Fluid Regimen 90 Cairo University Hospitals Cairo Egypt NCT06408584 Anhui Provincial Hospital Short-course Hypofractionated Radiotherapy in Combination With Raltitrexed and Tislelizumab March 1, 2024 Esophageal Squamous Cell Carcinoma esophageal squamous cell carcinoma tirelesizumab Raltitrexed Short course hypofractionated radiotherapy 59 Yuan He Hefei 230001 China NCT06408571 Zhongnan Hospital Study on the Pathogenesis of Retinal Vascular Diseases Based on Body Fluid Metabolomics September 7, 2023 Metabolomics; Retinopathy; Etiology etiology 3900 Zhongnan Hospital of Wuhan University Wuhan Hubei 430071 China NCT06408558 University of Surrey Safe Use of New Technologies in Diabetes in Flight January 28, 2023 Type1 Diabetes Postprandial glucose metabolism Hypobaric Ground level 12 David L. Russell-Jones Guildford Surrey GU2 7XH United Kingdom NCT06408545 Universidad Europea de Madrid Acceptance and Commitment Therapy for Problematic Chemsex March 1, 2024 Hypersexuality Compulsive Sexual Behavior Sexualized Drug Use (Chemsex) Sexuality Risky sexual behavior Acceptance and Commitment Therapy (ACT) 5 Universidad Europea de Madrid Villaviciosa de Odón Madrid 28670 Spain NCT06408532 Peking University People's Hospital The Efficacy and Safety of Insulin Degludec/Liraglutide Combination (IDegLira) in Patients With Type 2 Diabetes April 30, 2024 Diabetes Mellitus, Type 2 IDegLira Premixed insulin 256 NCT06408519 University Hospital, Basel, Switzerland Open-Label Placebo for Non-Specific Pain in the ED May 23, 2024 Pain, Acute open-label placebo non-specific pain emergency department Placebo (open-label) Ibuprofen 400 mg 50 NCT06408506 Medical University of Graz In-patient Comparison of Immediately Loaded and Non-loaded Submerged and Transgingival Healed Implants Within 4 Months September 28, 2017 Jaw, Edentulous Immediate loading Prei-implant bone regeneration Implant Survival Re-Entry Surgery Probing peri-implant bone Scanning peri-implant bone Conventional Impressions Implant Surgery Healing procedure 20 Dental Department Medical University of Graz Graz Styria 8010 Austria NCT06408493 Monash University Malaysia Peer-led Digital Health Lifestyle Intervention for a Low Income Community at Risk for Cardiovascular Diseases (MYCardio-PEER) March 1, 2024 Primary Prevention of Cardiovascular Diseases Peer-led Primary prevention Cardiovascular diseases Digital health Lifestyle intervention Peer support Community MYCardio-PEER 70 Monash University Subang Jaya Selangor 47500 Malaysia NCT06408480 Medical University of Graz Neonatologist-performed Lung Ultrasound in the Delivery Room May 1, 2024 Neonatal Disease neonatologist-performed lung ultrasound postnatal transition neonates Neonatologist-performed lung ultrasound 40 Division Neonatology, Dp. Pediatrics Graz Styria 8036 Austria NCT06408467 Lahanna oy Monitoring of Non-Surgical Treatment of Peri-implantitis January 1, 2022 Peri-implant Mucositis Peri-Implantitis peri-implant treatment aMMP-8 non-surgical treatment aMMP-8 diagnostic test 40 University of Helsinki Helsinki 00029 Finland NCT06408454 Kahramanmaras Sutcu Imam University Interleukin- 17 (IL-17), Bcl-3, and NF-kappa-B Inhibitor Zeta (IκBζ) Expression Levels in the Psoriasis Patients February 1, 2023 Psoriasis Periodontal Diseases psoriasis gene expression periodontal health Gingival crevicular fluid collection periodontal test 12 Ayşe Gül Öner Talmaç Kahramanmaraş Onikişubat 46000 Turkey NCT06408441 Fondazione IRCCS Istituto Nazionale dei Tumori, Milano The Epithelioid Hemangioendothelioma Registry of the European Reference Network on Rare Adult Solid Cancers (EURACAN) December 1, 2023 Epithelioid Hemangioendothelioma Sarcoma,Soft Tissue rare cancers soft tissue rare cancer registry protocol ultra rare sarcomas 100 University Hospital Graz Aarhus University Hospital Léon Bérard Center Essen University Hospital Azienda Ospedaliero Universitaria Careggi IRCCS Istituto Clinica Humanitas Azienda Ospedaliera Universitaria San Luigi Gonzaga Istituto Ortopedico Rizzoli Fondazione IRCCS Istituto Nazionale dei Tumori Istituto Oncologico Veneto Policlinico Universitario P. Giaccone Nuovo Ospedale di Prato "S.Stefano" Università Campus Bio-Medico Istituto Nazionale dei Tumori Regina Elena Oslo University hospital Ullevål Maria Skłodowska-Curie Institute of Oncology Vall d'Hebron University Hospital Hospital Universitario Fundación Jiménez Díaz Sahlgrenska University Hospital Karolinska University Hospital The Royal Marsden Hospital Graz Aarhus Lyon Essen Careggi Rozzano Orbassano Bologna Milan Padova Palermo Prato Roma Roma Oslo Warsaw Barcelona Madrid Göteborg Stockholm London Firenze Milano Torino 8036 8200 69008 45147 50134 20089 10043 40136 20133 35128 90127 59100 00128 00144 0450 00-001 08035 28040 413 45 171 76 SW3 6JJ Austria Denmark France Germany Italy Italy Italy Italy Italy Italy Italy Italy Italy Italy Norway Poland Spain Spain Sweden Sweden United Kingdom NCT06408428 Institut National de la Santé Et de la Recherche Médicale, France Glioma Intraoperative MicroElectroCorticoGraphy September 2024 Glioma Epilepsy Glioma surgery Awake surgery MicroElectroCorticoGraphy EEG PANAXIUM MicroECoG 50 Hôpital Pitié Salpêtrière Centre Hospitalier Sainte-Anne Hôpital Fondation Adolphe de Rothschild Paris Paris Paris 75013 75014 75019 France France France NCT06408415 Huashan Hospital A Study of the Higher Cognitive Functions of the Human Brain With Single-neuron Activity Recording May 2024 Cognition Electrodes, Implanted higher cognitive function single neural activity 10 Department of Neurosurgery, Huashan Hospital, Fudan University Shanghai Shanghai 200000 China NCT06408402 Assistance Publique - Hôpitaux de Paris Impact of Environmental Exposures on Tumor Risk in SDHx-mutation Carriers May 1, 2024 SDH-Related Familial Paraganglioma SDHx-Related Syndromes SDH Gene Mutation Environmental Exposure hereditary paraganglioma SDHx gene mutation environmental exposure 1300 CHU d'Angers CHU Jean Minjoz Besançon Hôpital Louis Pradel CHU de Caen Hôpital Michalon - CHU Grenoble CHU de Lille - Hôpital HURIEZ Hopital de la Conception - Marseille CHU de Montpellier - Hôpital Lapeyronie CHU de Nantes CHU de Nice -Hôpital Archet 2 Hôpital Pitié-Salpêtrière - APHP Hôpital Cochin - APHP Hôpital européen Georges Pompidou - APHP Hôpital européen Georges Pompidou - APHP CHU de Poitiers CHU de Rennes - Hôpital Sud Hôpitaux universitaire de Strasbourg - Hôpital de Hautepierre CHU de Toulouse - Hôpita Larrey CHU Bretonneau Institut Gustave Roussy Angers Besançon Bron Caen Grenoble Lille Marseille Montpellier Nantes Nice Paris Paris Paris Paris Poitiers Rennes Strasbourg Toulouse Tours Villejuif 49000 25030 69677 14033 38043 59037 13385 34295 44093 06202 75013 75014 75015 75015 86021 35000 67098 31059 37000 94805 France France France France France France France France France France France France France France France France France France France France NCT06408389 Assistance Publique - Hôpitaux de Paris Mechanics of Human Pre Implantation Development June 2024 Infertility In vitro fertilization embryo human time lapse pregnancy delivery machine learning 1500 NCT06408376 Hospital JP Garrahan Physiological Umbilical Cord Clamping in Patients With Congenital Diaphragmatic Hernia. Clinical Trial June 14, 2022 Umbilical Cord Clamping Congenital Diaphragmatic Hernia Delayed Umbilical Cord Separation Physiological cord clamping 80 Hospital de Pediatría S.A.M.I.C. "Prof. Dr. Juan P. Garrahan" Buenos Aires C1245AAM Argentina NCT06408363 Hospital Felicio Rocho Effectiveness of Sequential Eustachian Tube Maneuvers in Hyperbaric Oxygen Conditions September 1, 2023 Barotrauma;Ear Tympanum; Perforation Barotrauma Tympanic Membrane Perforation Eustachian Tube Hyperbaric Oxygenation Maneuver group 100 Hospital Felicio Rocho Belo Horizonte Minas Gerais 30110-934 Brazil NCT06408350 Friends Research Institute, Inc. Optimal Intervention to Full Viral Suppression: Text Me, Alexis! April 11, 2024 HIV HIV transgender women peer health navigation SMS, text messaging economic evaluation Text Me, Alexis! 195 Friends Community Center Los Angeles California 90028 United States NCT06408337 Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental Phase I-IIa, to Evaluate the Safety, Feasibility, and Efficacy of the Use of BIOCLEFT in the Treatment of Cleft Palate. April 17, 2024 Cleft Lip and Palate implantation with an autologous human palatal mucosa substitute made of nanostructured fibrin-agarose generated by tissue engineering (BIOCLEFT). 15 University Hospital Virgen de las Nieves Granada Spain/Granada 18014 Spain NCT06408324 European Research Consortium on ITP Evaluation of the Use of Thrombopoietin Receptor Agonists in Adults With Primary ITP in Europe November 24, 2022 Primary Immune Thrombocytopenia (ITP) Immune Thrombocytopenia ITP Thrombopoietin receptor agonists TPO-RA Eltrombopag Romiplostim 275 Hôpital Universitaire Henri Mondor CHU Dijon - Hôpital François Mitterrand Médecine 1 - Etudes Cliniques CHU Toulouse - Hôtel-Dieu Saint-Jacques Careggi Hospital Fondazione Policlinico A. Gemelli IRCCS San Bortolo Hospital, Vicenza Bergen Hospital Oslo Hospital Østfold Hospital Hospital del Mar, Barcelona Hospital General Universitario de Burgos Hospital Morales Meseguer Basel university hospital Bern university hospital Lausanne University hospital Imperial College NHS Trust University Hospitals Plymouth NHS Trust Créteil Dijon Toulouse Florence Roma Vicenza Bergen Oslo Oslo Barcelona Burgos Murcia Basel Bern Lausanne London Plymouth France France France Italy Italy Italy Norway Norway Norway Spain Spain Spain Switzerland Switzerland Switzerland United Kingdom United Kingdom NCT06408311 Encellin Safety of ENC-201-CED ENCRT May 1, 2024 Diabetes Mellitus, Type 1 Diabetes Mellitus Diabetes Mellitus, Type 1 Glucose Metabolism Islet Infusion Pancreas Transplant ENC-201-CED hPI 10 McGill University Health Centre Montréal Quebec H4A 3J1 Canada NCT06408298 Dartmouth-Hitchcock Medical Center HCQ in Resectable Localized Prostate Cancer June 2024 Resectable Localized Prostate Cancer Hydroxychloroquine Sulfate 400Mg Tab Placebo 20 NCT06408285 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. A Study of TQC3927 Powder for Inhalation in Healthy Adult Subjects May 2024 Chronic Obstructive Pulmonary Disease TQC3927 powder for inhalation TQC3927 powder for inhalation placebo 60 China Japan Friendship Hospital Beijing Beijing 100000 China NCT06408272 Central Hospital, Nancy, France Eit in ArdS for Tcav Setting (EAST Study) June 1, 2024 ARDS ARDS TCAV EIT APRV 12 Centre Hospitalier Régional Universitaire de Nancy Nancy 54500 France NCT06408259 Celgene Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis July 9, 2024 Multiple Sclerosis, Relapsing-Remitting Multiple Sclerosis Relapsing-Remitting Ozanimod Zeposia® Ozanimod Fingolimod Placebo 194 UCSF Benioff Children's Hospital San Francisco Axiom Clinical Research of Florida University of South Florida Washington University Medical College of Wisconsin San Francisco Tampa Tampa Saint Louis Milwaukee California Florida Florida Missouri Wisconsin 94158 33609 33612 63110 53226 United States United States United States United States United States NCT06408246 Stanford University Stanford and University of Illinois Chicago ACE-D Study February 1, 2026 Depression Guanfacine Sertraline 160 Stanford Psychiatry and Behavioral Sciences Department University of Illinois at Chicago Palo Alto Chicago California Illinois 94305 60607 United States United States NCT06408233 NYU Langone Health Person-Centered Quality Measurement and Management in a System for Addictions Treatment in New York State (Project 3) July 2024 Health Services Research Performance Coaching 35 NYU Langone Health New York New York 10016 United States NCT06408220 City of Hope Medical Center Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach Cancer June 11, 2024 Gastric Carcinoma Biopsy Biospecimen Collection Breath Test Esophagogastroduodenoscopy Questionnaire Administration 240 City of Hope Medical Center Duarte California 91010 United States NCT06408207 Children's Hospital Los Angeles CGM Academy for Youth With Type 1 Diabetes July 1, 2024 Type1 Diabetes Continuous Glucose Monitoring Glycemic Control Diabetes Education Type1 Diabetes CGM Academy 90 NCT06408194 Stanford University Autologous CD22 CAR T Cells Following Commercial CD19 CAR T Cells in B Cell Malignancies June 2024 Leukemia Acute Lymphoblastic Leukemia KYMRIAH CAR T Tisagenlecleucel Lymphodepletion CD22CART infusion Tisagenlecleucel 20 Stanford University Palo Alto California 94304 United States NCT06408181 University of Pennsylvania APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia May 2024 Pre-Eclampsia Pregnancy Loss Aspirin 162 mg Aspirin 81mg 1150 University of Pennsylvania Philadelphia Pennsylvania 19104 United States NCT06408168 M.D. Anderson Cancer Center Phase II Study of REPotrectinib With or Without Fulvestrant in Patients With Hormone Receptor-positive Human Epidermal Growth Factor 2-negative Metastatic Invasive LObular Carcinoma Who Received a Prior Endocrine Therapy in Combination With Cyclin-dependent Kinase 4 and 6 Inhibitor (REPLOT Trial) October 31, 2024 Hormone Receptor-positive Human Epidermal Growth Factor 2-negative Metastatic Invasive LObular Carcinoma Fulvestrant Repotrectinib 58 MD Anderson Cancer Center Houston Texas 77030 United States NCT06408155 Universita degli Studi di Genova Boosting Motor Task Performance: Insights From a Music and Encouragement Study April 13, 2024 Healthy motor recruitment motivation performance Isometric Task 30 Università degli Studi di Genova Genova 16122 Italy NCT06408142 Johns Hopkins University Universal Test and Connect for HIV Service Delivery in South Africa September 1, 2024 Human Immunodeficiency Virus Pre-Exposure Prophylaxis Emergency Department South Africa HIV testing 1573 NCT06408129 University Hospital, Montpellier COMPArison of Screening Strategies for Active TuBerculosis (COMPASS-TB) January 31, 2017 Active Tuberculosis Latent Tuberculosis Active Tuberculosis LAtent Tuberculosis infection Interferon-Gamma Release Assay Quantiferon Chest CT scan Chest X-ray 580 UH Montpellier Montpellier 34295 France NCT06408116 University Hospital Heidelberg Predicting Esophageal Cancer Borders Using PET-Imaging March 1, 2024 Esophagus Cancer, Stage I Esophagus Cancer, Stage II photon surgical therapy Chemotherapy 30 Department of Radiotherapy, University of Heidelberg Heidelberg 69120 Germany NCT06408103 Universidad de Santander Efficacy of a Multicomponent Intervention on Cognitive Function for the Caregiver-patient Dyad May 15, 2024 Mild Cognitive Impairment Rehabilitation Informal caregiver Transdisciplinary intervention Multi-component intervention Cognitive dysfunction Multi-component, transdisciplinary and multifocal intervention for the cognition 102 NCT06408090 University of Colorado, Denver Underutilization of Hospice Care in Older Black Adults June 2, 2023 Hospice Care Decision Aid Decision-Making Aging Knowledge Attitude IDECIDE-HOSPICE 400 University of Colorado Denver | Anschutz Medical Campus Aurora Colorado 80045 United States NCT06408077 University of Cologne Regulation of Extracellular Sodium in End Stage Renal Disease Upon Volume and Electrolyte Challenges July 1, 2023 Hyponatremia hyponatremia prospective trial intracellular measurements Water-Electrolyte Imbalance Water administration NaCl-Administration 60 Department II of Internal Medicine,University of Cologne Cologne 50937 Germany NCT06408064 Sanitas University The Effect of Music Therapy as an Adjuvant in the Vital Signs of the Neonate May 3, 2024 Neonatal Disease Music therapy 45 Clínica Universitaria Colombia Bogotá Colombia NCT06408051 Hisar Intercontinental Hospital Efficacy of 200 IU OnabotulinumtoxinA (Botulinum Toxin Type A) in Patients With Idiopathic Overactive Bladder Resistant to Anticholinergic Treatment: A Retrospective Analysis January 1, 2020 Idiopathic Overactive Bladder Resistant to Anticholinergic Treatment Injection of onabotulinumtoxinA into the bladder wall 60 Basri Cakiroglu Hisar Intercontinental Hospital Istanbul Istanbul 34768 34768 Turkey Turkey NCT06408038 Institut Claudius Regaud Are CK+/CD45+ Double-Positive Circulating Cells of Tumor-origin? Characterization in METAstatic Breast Cancer June 2024 Metastatic Breast Cancer Metastatic Breast Cancer CK+/CD45+ Double-Positive circulating cells For each patient included, the samples described below will be collected: 60 IUCT-O Toulouse 31059 France NCT06408025 Indiana University Syrenity App for Depression May 1, 2024 Depressive Symptoms Syrenity App 300 NCT06408012 St. Joseph's Healthcare Hamilton An Innovative Master Platform for Clinical Trials in Mood Disorders October 17, 2023 Mood Disorders Depressive Disorder Bipolar and Related Disorders 900 University of Calgary University of British Columbia Nova Scotia Health Authority McMaster University Queen's University University of Ottawa University Health Network Centre for Addiction and Mental Health Calgary Vancouver Halifax Hamilton Kingston Ottawa Toronto Toronto Alberta British Columbia Nova Scotia Ontario Ontario Ontario Ontario Ontario T2N 4Z6 V6T 2A1 B3H 2E2 L8P 3B6 K7L4X3 K1Z 7K4 M5T 2S8 M6J 1H4 Canada Canada Canada Canada Canada Canada Canada Canada NCT06407999 SleepRes Inc. Pressure Relief Algorithm Eval May 15, 2024 Obstructive Sleep Apnea Expiratory Pressure Relief 50 Sleep Centers of Middle Tennessee Murfreesboro Tennessee 37129 United States NCT06407986 Sir Run Run Shaw Hospital Pulmonary Ventilation Heterogeneity Determined by EIT During PFT in Subjects With Normal One-second Rates December 5, 2023 PRISm pulmonary function test 60 Sir Run Run Shaw Hospital Hangzhou Zhejiang 310000 China NCT06407973 Sight Sciences, Inc. A Clinical Trial Comparing the OMNI Surgical System to Standard Medical Treatment in Pseudophakic Eyes April 30, 2024 Primary Open Angle Glaucoma OMNI Surgical System Latanoprost plus adjunctive glaucoma medication 334 North Bay Eye Associates University Eye Specialists Petaluma Maryville California Tennessee 94954 37803 United States United States NCT06407960 Shanghai University of Traditional Chinese Medicine The Clinical Study of Foot Function Index in Adolescent Flatfoot January 1, 2022 Foot Function Index, Flat Foot, Dynamic Plantar Pressure, Reliability, Validity 97 Shanghai University of Traditional Chinese Medicine Shanghai Shanhai 200000 China NCT06407947 Shanghai Changzheng Hospital Study of CT071 Injection in HRNDMM May 22, 2024 High-risk Newly Diagnosed Multiple Myeloma (HRNDMM) High-risk Newly Diagnosed Multiple Myeloma (HRNDMM) CAR-T CAR-T cells Infusion 10 NCT06407934 Sanofi A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Monotherapy Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis May 8, 2024 Dermatitis Atopic Amlitelimab Placebo 961 Florida International Research Center Site Number : 8401091 Miami Florida 33173 United States NCT06407921 Riphah International University Whole Body Vibration and BOSU Ball in Spastic Cerebral Palsy May 15, 2024 Spastic Cerebral Palsy cerebral palsy WBVT bosu ball functional mobility balance Whole Body Vibration BOSU ball 32 Riphah International University Lahore Punjab 54000 Pakistan NCT06407908 Riphah International University Urdu Translation Of Pediatric Version Of Eating Assessment Tool May 15, 2024 Cerebral Palsy validation translation eating disorder PEDI-EAT-10 42 Imran Amjad Lahore Punjab 54000 Pakistan NCT06407895 Riphah International University Effects of Lower Limb Fitness Program in Children With DS May 15, 2024 Down Syndrome Down Syndrome, Lower Limb Fitness Program, Dynamic Balance Lower Limb Fitness Program Routine Therapy 28 Riphah International University Lahore Punjab 54000 Pakistan NCT06407882 Riphah International University Effects of Conductive Exercises on Motor Skills Among the Children With CP May 15, 2024 Cerebral Palsy ADLS, Cerebral palsy, Motor skills, Quality of life Conductive Exercises 56 Riphah International University Lahore Punjab 54000 Pakistan NCT06407869 Riphah International University Effects of Functional Progressive Strength Training in Children With Spastic Cerebral Palsy May 15, 2024 Spastic Cerebral Palsy Spastic CP, Functional Progressive Strength Training Functional Progressive Strength Training 40 Riphah International University Lahore Punjab 54000 Pakistan NCT06407856 Riphah International University Dual Task Training in Spastic Cerebral Palsy May 15, 2024 Spastic Cerebral Palsy cerebral palsy Dual-Task Training Gait, Balance Cognitive-motor interference conventional therapy Dual Task Training 32 Imran Amjad Lahore Punjab Pakistan NCT06407843 Riphah International University Effects of Schroth Method in Idiopathic Scoliosis May 15, 2024 Idiopathic Scoliosis Cobb angle Chest mobility Idiopathic scoliosis Lumbar muscle endurance Schroth Exercise therapy Schroth Method Regular Physical Therapy 32 NCT06407830 Riphah International University Effect of MRP With and Without EMS on Gait, Functional Independence and QOL in Stroke Patients May 1, 2024 Stroke Gait Functional independence Quality of life motor relearning programme electrical muscle stimulations with motor relearning programme 66 Rehabilitation Center Lahore Punjab 54600 Pakistan NCT06407817 Riphah International University Comparative Effects Of Spencer and Reverse Distraction Technique In Patients With Adhesive Capsulitis February 1, 2024 Spencer and Reverse Distraction Technique Spencer technique reverse distraction technique 50 Johar Pain Relief Center Lahore Punjab 54782 Pakistan NCT06407804 Riphah International University Effects of Thrower's Ten and Routine Physical Therapy in Patients With Shoulder Impingement Syndrome February 1, 2024 Shoulder Impingement Syndrome Thrower's Ten Exercise Program Routine physical therapy. 46 Johar Pain Relief Center Lahore Punjab 54782 Pakistan NCT06407791 Carilion Clinic Clinical Evaluation of a Device for Treatment of Lymphedema of the Upper Extremity May 1, 2024 Lymphedema Lymphedema Arm Lymphedema of Upper Arm LymphaVibe 15 Carilion Clinic Roanoke Virginia 24014 United States NCT06407778 Riphah International University Comparison of High Intensity Strength Training and Muscle Energy Techniques in TKR Patients May 15, 2024 Knee Osteoarthritis Arthroplasty, Knee Replacement Resistance Training Total Knee Replacement Knee Osteoarthritis Strength Training Muscle Energy Technique High Intensity Strength Training Muscle Energy Technique 36 Horizon Hospital Lahore Lahore Punjab 05450 Pakistan NCT06407765 Riphah International University Effects of Dual Task Training on Balance, Activity and Participation in Children With Cerebral Palsy May 16, 2024 Cerebral Palsy Cerebral Palsy Dual task training Backward Walking Activity Balance Dual task training Dual task training with backward walking 44 Riphah international university Lahore Punjab 540000 Pakistan NCT06407752 Riphah International University Anthropometric Characteristics, Level of Physical Fitness, and Muscle Strength in Youngsters Attending School May 27, 2024 Physical Fitness Anthropometric parameter, Dynamometer. Conicity index. 285 Riphah international university lahore Lahore Punjab 54000 Pakistan NCT06407739 Riphah International University Three Phase Physical Therapy in Children With Relapsed Club Foot After Ponseti Treatment May 15, 2024 Club Foot Club foot Ponseti technique Three-phase physical therapy Three-Phase Physical Therapy Intervention 19 NCT06407726 Riphah International University Comparative Effects of Virtual Reality and Vestibular Exercises on Balance Gait in Older Adults May 1, 2024 Old Age Vestibular Disorder Balance Exercise Old Age Vestibular Disorder Balance Exercise virtual reality training group vestibular exercise group 44 Riphah International University Lahore Fedral 44000 Pakistan NCT06407713 Riphah International University Intrinsic Foot Muscle Training With and Without Hip Abductor Muscle Strengthening in Pronation Distortion Syndrome May 2, 2024 Pronation Deformity of the Foot Exercise, Muscle Strength, Navicular drop, Pronation. Intrinsic foot muscle training Hip abductor muscle training 26 Nawaz Sharif social security hospital Lahore Punjab 54500 Pakistan NCT06407700 Riphah International University Comparison of Brugger's Exercise With and Without Kendall Exercises in Sterno-Symphyseal Syndrome May 2, 2024 Upper Crossed Syndrome Craniovertebral Anglle. Exercise Pain Posture Sterno-symphyseal Syndrome Brugger's exercise. Kendall Exercise. 32 Umar Trust Hospital Lahore Punjab 54000 Pakistan NCT06407687 Riphah International University Compare Electrodry Needlig and Dry Needling in Mechanical Low Back Pain May 3, 2024 Quadratus Lumborum Syndrome Dry Needling Endurance pain range of motion Quadratus Lumborum Syndrome Electro Dry Needlig dry needling 26 Ali Afzal Shah Dispensary Lahore Punjab 05499 Pakistan NCT06407674 IRCCS San Raffaele Non-invasive Assessment of RECTUM (POUCH) by US (RECT-US) in a Cohort of IBD Patients January 10, 2024 Ulcerative Colitis Crohn's Disease intestinal ultrasound Ileocolonoscopy Trans-perineal ultrasound 150 Irccs San Rafael Hospital Milan 20132 Italy NCT06407661 Izmir Democracy University Disaster Nursing Course Affect Nursing Students' Disaster Literacy and Preparedness September 27, 2021 Literacy literacy nursing student "Disaster Nursing" course/education 62 İzmir Democracy University İzmir Ege Bölgesi 35560 Turkey NCT06407648 Johns Hopkins University Using Personalized Assessments in the Treatment of Childhood OCD April 3, 2024 Obsessive-Compulsive Disorder children adolescents exposure with response prevention cognitive behavioral therapy ERP CBT Personalized Assessments Standard of Care 30 Johns Hopkins University School of Medicine Baltimore Maryland 21287 United States NCT06407635 Johns Hopkins University A Study of Psilocybin for PTSD May 2024 Post Traumatic Stress Disorder Psilocybin Trauma-focused psychotherapy Standard psychological support 20 NCT06407622 Bartın Unıversity The Effect of Foot Reflexology on Patients Undergoing Appendectomy Surgery January 1, 2023 Nursing Pain Reflexology Abdominal Pain Sleep Quality Bowel Functions Appendectomy Nursing Pain Reflexology Abdominal Pain Sleep Quality Bowel Functions Appendectomy Foot Reflexology 120 Bartın University Bartın Centrical 74100 Turkey NCT06407609 Azienda di Servizi alla Persona di Pavia Positive Outcomes of the Supplementation With Lecithin-based Delivery Form of Curcuma Longa and of Boswellia Serrata in IBS September 3, 2022 Boswellia Serrata Irritable Bowel Syndrome Bloating Dysbiosis Boswellia serrata Curcuma longa Irritable bowel syndrome Microbiota Phytosome Curcuma and boswellia extracts plus low fodmap diet Low Foodmap diet 64 Mariangela Rondanelli Pavia PV 27100 Italy NCT06407596 Ankara City Hospital Bilkent HILT or Conventional Combined Physical Therapy, in the Management of Hemiplegic Shoulder Pain June 1, 2022 Hemiplegic Shoulder Pain Hemiplegia Physical Therapy High Intensity Laser high intensity laser tens+us 42 Ankara City Hospital Ankara Çankaya 06800 Turkey NCT06407583 Amsterdam University of Applied Sciences ProMIO2.0; A Powerful Lifestyle Intervention for Older Adults From Ethnic Minorities May 24, 2022 Sarcopenia Diabetes Overweight Ethnic Minorities Musculoskeletal Diseases Lifestyle intervention Protein Multicomponent exercise Older adults Ethnic minorities ProMIO2.0 program 76 Amsterdam University of Applied Sciences, Center of Expertise Urban Vitality Amsterdam N-H 1067SM Netherlands NCT06407570 University of Aarhus Dysphagia and Quality of Life in Patients With Oral Squamous Cell Carcinoma Before and After Treatment June 1, 2024 Oral Cavity Cancer Dysphagia Quality of Life Oral Cavity Cancer Dysphagia Quality of Life Days alive and out of hospital Rehabilitation 100 Aarhus University Hospital Aarhus Denmark NCT06407557 Swansea University Optimizing Older Adults' Home Space for Physical Activity January 1, 2024 Activity Accelerometer 23 Swansea University Swansea SA1 8EN United Kingdom NCT06407544 Sohag University Prospective Comparative Study Between Ultrasound-guided Quadratus Lumborum Block Versus Fascia Iliaca Compartment Block for Postoperative Pain and Cognitive Dysfunction Management in Patient Undergoing Hip Surgery May 2024 Pain and Cognitive Dysfunction Management in Hip Surgery peripheral nerve block PCA device as rescue medication with IV morphine 1mg if VAS more than 4 60 NCT06407531 Akdeniz University Before Colonoscopy Effect of Virtual Reality Application on Anxiety and Vital Signs November 21, 2023 Colonoscopy virtual reality glasses surgical nursing colonoscopy VR-G 70 Finike State Hospital Antalya Finike 07740 Turkey NCT06407518 Sixth Affiliated Hospital, Sun Yat-sen University Preoperative Oral Midazolam to Postoperative Pain Relief in Sleep Disturbance or Anxiety Patients With Colorectal Cancer May 2024 Preoperative Sleep Disturbance Anxiety Midazolam Pain, Postoperative preoperative oral midazolam sleep disturbance anxiety postoperative pain colorectal cancer Midazolam oral solution Placebo 280 the Sixth Affiliated Hospital, Sun Yat-sen University Guangzhou Guangdong 510655 China NCT06407505 Uskudar University The Effect of LI4 Acupressure on Perineal Pain and Postpartum Comfort During Episiotomy Repair June 1, 2024 Labor Pain Perineal Pain Postpartum Comfort Acupressure, LI4 acupoint, Perineal pain, Postpartum comfort Acupressure group Placebo group 90 NCT06407492 Uskudar University Complementary Medicine Practices in Chronic Low Back Pain: Randomized Controlled Trial May 9, 2024 Back Pain Leeches Chronic Pain Leech Conventional Physiotherapy Kinesiotape 60 Uskudar university Istanbul Turkey NCT06407479 Uskudar University Comparison of Eccentric Muscle Training and Proprioceptive Neuromuscular Facilitation Techniques in Neck Pain May 9, 2024 Neck Pain Chronic Pain proprioceptive neuromuscular facilitation technique group eccentric muscle training technique application group Control 45 Uskudar University Istanbul Turkey NCT06407466 Uskudar University The Effect of Soft Tissue Mobilization and Kinesio Taping Applied to Athletics Athletes on Sports Performance May 9, 2024 Athletic Injuries Sports Physical Therapy taping Control mobilization 45 Uskudar Üniversity Istanbul Turkey NCT06407453 Uskudar University Effectiveness of Exercise Given With Ergonomics Training in Tea Workers May 9, 2024 Neck Pain Back Pain Work-related Illness control exercise 60 Uskudar Üniversity Istanbul Turkey NCT06407440 Uskudar University The Effect of Exercise Given to Cashiers Along With Ergonomics Training on Pain and Work Performance May 9, 2024 Work-related Illness Work Related Upper Limb Disorder control exercise 60 Uskudar University Istanbul Turkey NCT06407427 Yale University Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation June 2024 Postoperative Rehabilitation App for in-bed conditioning exercises Usual care 100 NCT06407414 Uskudar University Effectiveness of Neuromuscular Exercise in Patellofemoral Pain Syndrome May 20, 2024 Patellofemoral Pain Syndrome control Exercise 50 NCT06407401 European Organisation for Research and Treatment of Cancer - EORTC Improvement of Quality of Life Through Supportive Treatments for Hormone Therapy - Related Symptoms in Women With Early Breast Cancer; A Pragmatic Randomized Controlled Trial December 2024 ER+ Breast Cancer HER2-negative Breast Cancer Breast Cancer Stage I Breast Cancer Stage II Breast Cancer Stage III Drug-Related Side Effects and Adverse Reactions Musculoskeletal Pain Quality of Life Duloxetine 60 MG Furosemide 40 mg Booklet for healthy behaviors 399 NCT06407388 Eastern Virginia Medical School Ultrasound Findings in Diabetic Pregnancies June 1, 2023 Diabetes 156 Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Eastern Virginia Medical School Norfolk Virginia 23507 United States NCT06407375 University of Zurich Assessment of Renal Function by Multiparametric MRI May 1, 2023 Renal Impairment mpMRI 200 University Hospital Zurich Zurich ZH 8091 Switzerland NCT06407362 Sanliurfa Mehmet Akif Inan Education and Research Hospital Effects of Volume and Pressure-Controlled Ventilation on Cerebral SpO2, PI, and PVI Index in Septoplasty May 15, 2021 Ventilation Mode Pleth Variability Index Perfusion Index Regional Cerebral Oxygen Saturation Cerebral Oxygen Saturation 50 University of Health Science Turkey Sanliurfa Mehmet Akif Inan Training and Research Hospital Şanlıurfa 63050 Turkey NCT06407349 Riphah International University Effect of Communication Board on Functional Communication of Children With Cerebral Palsy May 6, 2024 Cerebral Palsy (CP) Communication Board Traditional Therapy 20 Special Education Academy Rawalpindi Punjab 46620 Pakistan NCT06407336 Superior University Comparative Effect of Cylindrical Lenses Verses Spherical Equilient on Contrast Sensitivity October 1, 2023 Low Vision Aids Contrast sensitivity Refraction 68 Sehat Medical Complex Hanjarwal Lahore Punjab Pakistan NCT06407323 Superior University Pediatric Rehabilitation for Children With Cerebral Palsy Through PVT Using AI to Reduce Spasticity October 1, 2023 Cerebral Palsy Personalized vibration therapy powered by AI Physical therapy treatment 32 Johar pain relief center Ali Fatima hospital Lahore Lahore Punjab Punjab 54600 Pakistan Pakistan NCT06407310 Tel Aviv Medical Center Neoadjuvant Pembrolizumab, Carboplatin and Paclitaxel in Triple-negative Breast Cancer July 1, 2024 Triple Negative Breast Cancer Immunotherapy Pembrolizumab Breast cancer Triple-negative breast cancer Pembrolizumab Carboplatin Paclitaxel 25 NCT06407297 Shanghai Changzheng Hospital UCMSCs Combined With Standard Therapy for the Treatment of Newly Diagnosed Type 1 Diabetes May 1, 2024 Newly Diagnosed Type 1 Diabetes Mellitus UCMSCs Placebo 24 Shanghai Changzheng Hospital Shanghai Shanghai China NCT06407284 The University of Texas Health Science Center, Houston Brighter Bites/Legacy Produce Rx Program May 1, 2024 Child Obesity Produce Prescription Group Control Group 600 The University of Texas Health Science Center at Houston Houston Texas 77030 United States NCT06407271 Semmelweis University Effect of Abutment Configuration on Peri-implant Soft and Hard Tissue in the Esthetic Zone - Randomized Clinical Trial December 13, 2023 Dental Implants, Single-Tooth Dental Implant-Abutment Design Peri-Implant Tissue Management CAD-CAM Dental Implants, Single-Tooth Dental Implant-Abutment Design CAD/CAM custom ZrO2 healing abutment Cylindrical ZrO2 healing abutment 30 Semmelweis University, Department of Prosthodontics Budapest Pest 1088 Hungary NCT06407258 University of Basel Promoting Sleep and Physical Activity Among Adolescent Psychiatric Patients June 1, 2024 Mental Disorder in Adolescence Insomnia Delayed Sleep-Wake Phase Disorder adolescents CBT-I light therapy circadian adaptation physical activity counseling transdiagnostic SLEEPAC 140 University Hospital of Child and Adolescent Psychiatry and Psychotherapy Department of Sport, Exercise, and Health, University of Basel Bern Basel BE BS 3000 4052 Switzerland Switzerland NCT06407245 University of British Columbia Efficacy of Exercise Snacks in Real-World Settings in Individuals Living With Type 2 Diabetes April 20, 2024 Type 2 Diabetes Exercise Snacks Placebo Exercise 80 University of British Columbia Okanagan Kelowna British Columbia V1V 3G1 Canada NCT06407232 University of Wisconsin, Madison Letermovir (Prevymis) for CMV in Kidney and Pancreas Transplant Recipients May 2024 Cytomegalovirus Infections Kidney Transplant Infection Pancreas Transplant Letermovir 90 UW Hospital and Clinics Madison Wisconsin 53792 United States NCT06407219 University of Calgary Evaluating the Impacts of a Single Session of Robot Assisted Gait Training With a Trexo March 14, 2022 Physical Disability CP (Cerebral Palsy) Developmental Disability Robot Assisted Gait Training Trexo Rehabilitation Robot Assisted Gait Training 50 Alberta Children's Hospital Calgary Alberta T3B 6A8 Canada NCT06407206 Riphah International University Effects of Sub Occipital Muscle Inhibition Technique in Mechanical Low Back Pain April 1, 2024 Mechanical Low Back Pain mechanical low back pain sub occipital muscle inhibition hamstring flexibility Sub occipital muscle inhibition technique and conventional therapy conventional therapy 36 Dr. Ali Therapy clinic Islamabad Punjab 46000 Pakistan NCT06407193 Rijnstate Hospital Gastric Emptying After Sleeve Gastrectomy May 10, 2022 Gastric Emptying Bariatric Surgery Gastric emptying Gastric sleeve MRI Scintigraphy MRI and scintigraphy 6 Rijnstate Hospital Arnhem Gelderland 6815AD Netherlands NCT06407180 Ramathibodi Hospital Efficacy of Intra-Articular Corticosteroid Injections on Clinical Outcomes in Patients With Operative Distal Radius Fractures July 1, 2024 Wrist Fractures Intraarticular Injection Wrist Fractures intraarticular injection corticosteroids Triamcinolone Acetonide Normal saline 58 NCT06407167 N.N. Priorov National Medical Research Center of Traumatology and Orthopedics Neuropathic Pain in Patients With Degenerative Lumbar Stenosis May 13, 2024 Lumbar Spinal Stenosis Neuropathic Pain Spinal Disease DN4 (Douleur Neuropathique 4 Questions) questionnaire 120 Priorov National Medical Research Center of Traumatology and Orthopedics Moscow 127299 Russian Federation NCT06407154 Universitätsklinikum Hamburg-Eppendorf Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study, 2nd Wave May 15, 2024 Coronary Disease Myocardial Infarction Heart Failure Arrhythmias, Cardiac Peripheral Artery Disease Stroke Ischemic Attack, Transient Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Pulmonary Disease, Chronic Obstructive Asthma Renal Insufficiency Depressive Disorder Anxiety Disorders Schizophrenia Peripheral Nervous System Diseases 640 NCT06407141 The University of Hong Kong The Effect of TPS on Cognitive Functions in Older Adults With MCI May 8, 2024 Mild Cognitive Impairment transcranial pulse stimulation 100 NCT06407128 University Hospital, Toulouse Valvular Microbiota and Valvulopathy January 9, 2024 Valvulopathy Microbiota Collection of biological samples 100 University Hospital Toulouse 31059 France NCT06407115 University of Washington Adapting and Implementing a Nurse Care Management Model to Care for Rural Patients With Chronic Pain May 8, 2024 Chronic Pain chronic pain behavioral health rural health telehealth exercise Cognitive Behavioral Therapy (CBT) Enhance Fitness Care Coordination 30 Atrium Health/Wake Forest Baptist Winston-Salem North Carolina 27157 United States NCT06407102 University Hospital, Tours Collection of Primary Human May 2, 2024 Collection of Nasal Cells nasal cells Respiratory epithelium Collection of nasal cells during programme surgery 100 NCT06407089 Universitat Internacional de Catalunya Effectiveness of a Telerehabilitation Program Based on Specific Neck Exercises in Patients With Forward Head Posture. May 20, 2024 Forward Head Posture Neck Pain Telerrehabilitation Deep Cervical Muscles Specific Neck Exercises Neck Muscles Exercise Therapy Spinertial Group 52 Élite Fisioterapia, María Montessori 2. Zaragoza 50018 Spain NCT06407076 University of Oviedo Strengths and Weaknesses of Physiotherapy in the Daily Work of an Intensive Care Unit May 9, 2024 Healthcare Interviews 18 University of Oviedo Oviedo Asturias 33006 Spain NCT06407063 University Hospital of North Norway Long-term Reoperations After Lumbar Spinal Stenosis Surgery September 19, 2007 Degenerative Lumbar Spondylolisthesis Degenerative Spondylolisthesis Treatment Decompression alone Intrumented fusion Reoperations Micro-decompression alone Decompression and instrumented fusion 794 NCT06407050 University of Texas at Austin Duration of Physical Inactivity and Postprandial Lipid Metabolism April 1, 2024 Metabolism 4 hours of physical inactivity 8 hours of physical inactivity 12 hours of physical inactivity 12 The University of Texas at Austin Austin Texas 78712 United States NCT06407037 Diskapi Yildirim Beyazit Education and Research Hospital Comparison of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block December 27, 2023 Erector Spinae Plane Block Serratus Posterior Superior Intercostal Plane Block Acute Pain Postoperative Pain Breast Neoplasms Erector Spinae Plane Block Serratus Posterior Superior Intercostal Plane Block 25 Ankara Etlik City Hospital Yenimahalle Ankara 06170 Turkey NCT06407024 The Cleveland Clinic Laparoscopic Versus Robotic Lateral Transabdominal Adrenalectomy June 1, 2024 Adrenalectomy laparoscopic transabdominal adrenalectomy robotic transabdominal adrenalectomy 54 The Cleveland Clinic Foundation Cleveland Ohio 44195 United States NCT06407011 Chulalongkorn University Effects of Swedish Massage Prior Circuit Breathing Training on Asthma January 15, 2024 Asthma; Status Asthma Circuit breathing Swedish massage Pulmonary function Asthma control Control Swedish massage prior circuit breathing training group (SBT) Circuit breathing training group (CBT) 30 Faculty of Sports Science, Chulalongkorn University Pathum Wan Bangkok 10330 Thailand NCT06406998 Samsung Medical Center Maternal and Offspring Outcomes in Pregnant Women With Pre-existing ASCVD January 1, 2021 Cardiovascular Diseases Atherosclerosis Pregnancy Complications Adverse Cardiac Event Adverse Birth Outcomes Atherosclerotic cardiovascular disease Major adverse cardiac and cerebrovascular event Adverse pregnancy outcome Adverse birth outcomes Pre-existing atherosclerotic cardiovascular disease 5461222 Samsung Medical Center Seoul Korea, Republic of NCT06406985 University of Illinois at Urbana-Champaign Developing a Weight Management Class as a Recruitment Tool for an Online Weight Loss Program to Rural Illinois Residents May 7, 2024 Overweight and Obesity Weight-loss through dietary and lifestyle changes 20 NCT06406972 Region Skane Brief Admission by Self-referral for Individuals With Self-harm: Effects on Compulsory Care September 15, 2010 Self-injury Suicide Suicide, Attempted Self-harm Borderline Personality Disorder Emergency Psychiatric Hospitalizations Psychiatric Brief Admission by self-referral self-harm traits of borderline personality disorder compulsory care Brief Admission by self-referral (BA) 7000 Division of Psychiatry, Region Skåne Region Östergötland Statistiska centralbyrån Socialstyrelsen Lund Linköping Solna Stockholm Skåne 22185 581 91 171 54 SE-106 30 Sweden Sweden Sweden Sweden NCT06406959 Pirogov Russian National Research Medical University The Effect of Preemptive Regional Anesthesia (TAP-block) on Acute and Chronic Pain After Transabdominal Preperitoneal Inguinal Hernia Repair (TAPP) March 1, 2024 Primary Inguinal Hernia transverse abdominis plane block inguinal hernia TAPP technique chronic postoperative pain acute pain inguinal hernia surgery Transversus abdominal plane block (TAP block) 78 Department of faculty surgery №1 Pirogov Russian National Research Medical University Moscow 117997 Russian Federation NCT06406946 Northumbria University Mushrooms, Mood and Mental Wellbeing in Gen Z Women April 15, 2024 Well-Being, Psychological Mood Anxiety Stress Lion's mane blend Lion's mane and reishi blend Placebo 135 Brain, Performance and Nutrition Research Centre, Northumbria University Newcastle Upon Tyne Tyne And Wear NE1 8ST United Kingdom NCT06406933 Chang Gung Memorial Hospital Salivary Conductivity Screening for Primary Sjögren's Syndrome July 1, 2023 Sjogren's Syndrome Dry Eye Syndromes dry eye disease, Sjögren syndrome, salivary conductivity Carbomer Gel/Jelly 200 Department of Ophthalmology, Chang Gung Memorial Hospital Pizi 613 Taiwan NCT06406920 Medical University of Gdansk Intravascular Clotting (POCUS) - Marker of the Timing and Severity of Cardiac Arrest; Indicator of Futile Resuscitation April 29, 2024 Cardiac Arrest cardiopulmonary resuscitation CPR point-of-care ultrasound POCUS intravascular clotting 40 University Clinical Centre - Clinical Emergency Department Gdańsk Pomorskie 80-214 Poland NCT06406907 Riphah International University Effects of Short Duration Blood Flow Restriction Training on Musculoskeletal and Performance Outcomes May 15, 2024 Blood Flow Restriction Training Blood flow restriction Surface EMG Reactive strength index Abdominal muscles High Frequency Blood Flow Restriction Training Group Low Frequency Blood Flow Restriction Training Group High Frequency Blood Flow Restriction Training Instability Group Low Frequency Blood Flow Restriction Training Instability Group Control Group 50 Woodlands Health Center Islamabad 44000 Pakistan NCT06406894 Riphah International University Effect of Superficial Back Line Relaxation Technique on Hamstring Flexibility in Non Specific Low Back Pain Patients March 1, 2024 Low Back Pain, Mechanical Hamstring Flexibility hamstring flexibility backache Suboccipital muscle inhibition technique cranial cervical flexion exercise Conventional physical therapy Superficial back line relaxation (SMIT & CCFE) 44 Railway General hospital Rawalpindi Punjab 46000 Pakistan NCT06406881 Riphah International University Combine Effect Of Myofascial Release Technique and Ocular Muscle Exercise Among University Students March 1, 2024 Headache physical therapy myofascial release therapy 36 Abasyn university peshawar Peshawar Khyber Pakhtunkhawa Pakistan NCT06406868 Riphah International University Outpatient Versus Tele Rehabilitation Among Post-surgical Breast Cancer Survivors February 7, 2024 Breast Cancer Shoulder Functional Independece American Cancer Society 44 Nishtar Hospital Multān Punjab 66000 Pakistan NCT06406855 University of Miami Brain-Controlled Spinal Stimulation Walking Therapy After Incomplete Spinal Cord Injury (SCI) July 31, 2024 Spinal Cord Injuries BCI-TSCS 12 University of Miami Miami Florida 33136 United States NCT06406842 Beijing Tiantan Hospital Association Between Local Cerebral Oxygenation Monitoring and Postoperative Stroke in Carotid Endarterectomy May 15, 2024 Carotid Endarterectomy Cerebral Autoregulation Cerebral Oxygenation index guided hemodynamics management routine hemodynamics management 560 Beijing Tian Tan Hospital, Capital Medical University Beijing Beijing 100160 China NCT06406829 Beijing Tiantan Hospital Perioperative Multimodal Analgesia Protocol for Supratentorial Craniotomy June 1, 2024 Postoperative Pain Analgesia Supratentorial Brain Tumor multimodal analgesia Postoperative acute pain Dexmedetomidine Normal saline Local analgesic techniques no Local analgesic techniques 2000 NCT06406816 Meng Chao Hepatobiliary Hospital of Fujian Medical University Neoantigen Vaccine Plus Capecitabine as Adjuvant Therapy for Intrahepatic Cholangiocarcinoma After Radical Resection May 2024 Intrahepatic Cholangiocarcinoma Neoantigen Vaccine plus Capecitabine 10 NCT06406803 Maastricht University Medical Center The Impact of Physical Activity Versus Dietary Energy Restriction on Tumour and Muscle Protein Synthesis in Prostate Cancer Patients May 2024 Cancer of Prostate Dietary energy restriction Daily exercise 45 NCT06406790 Pramand LLC CraniSeal Post Approval Study June 2024 Leak, Cerebrospinal Fluid CraniSeal DuraSeal 224 NCT06406777 University of Iowa Chronic Lung Allograft Dysfunction MRI Study July 2024 Lung MRI Imaging CLAD Oxygen Enhanced MRI Hyperpolarized Gas MRI Lung Transplant Spirometry Contrast Lung Computed Tomography (CT) Scan Oxygen enhanced magnetic resonance imaging (OE-MRI) Scan 129Xe MRI scans 100 NCT06406764 Palacky University Effects of a Plyometric Training Program on Youths With Different Biological Maturity in Sport May 13, 2024 Athletic Performance Muscle Fatigue Plyometric Exercise Plyometric training Control training 30 Palacky University, Faculty of Physical Culture Olomouc 77111 Czechia NCT06406751 University of Iowa Microbiome Effects of Extended Use of MI Paste in Elderly Removable Denture Wearers May 2024 Dental Prosthesis MI Paste 60 University of Iowa College of Dentistry Iowa City Iowa 52242 United States NCT06406738 Ondokuz Mayıs University Simulator Use in Newborn First Care May 15, 2024 Newborn; Vitality Using High Reality Simulator 66 NCT06406725 Northwell Health Detection of Vocal Fold Motion Impairment on Noninvasive Positive Pressure March 30, 2024 Vocal Cord Dysfunction Vocal Cord Paralysis Vocal Cord Paresis Recurrent Laryngeal Nerve Palsy Recurrent Laryngeal Nerve Injuries Point-of-Care Ultrasound of the Airway 50 Cohen Children's Medical Center Queens New York 11040 United States NCT06406712 New Valley University Retroclavicular Block in Vascular Surgey June 1, 2024 Pain Management retroclavicular block 80 NCT06406699 University of Colorado, Denver Feasibility and Acceptability of Group Pain Reprocessing Therapy for Veterans With Chronic Neck/Back Pain April 17, 2024 Chronic Back Pain Chronic Pain Neck Pain Back Pain Pain Reprocessing Therapy (PRT) 40 University of Colorado - Anschutz Medical Campus VA Aurora Colorado 80045 United States NCT06406686 University of Calgary Ablation Index in Standard vs. High Power Radiofrequency Ablation for Typical Atrial Flutter: A Randomized Study (AITAF) June 3, 2024 Atrial Flutter Atrial Flutter Typical Cavotricuspid Isthmus Dependent Macroreentry Tachycardia Ablation High power short duration CARTO QDot Micro Ablation Index Ablation of the Cavo-tricuspid isthmus for typical Atrial Flutter 50 University of Calgary Calgary Alberta T2N 4Z6 Canada NCT06406673 Henan Cancer Hospital A Phase II Clinical Study of Cadonilimab in Treatment-naïve or Relapsed Extensive Small Cell Lung Cancer October 16, 2023 Extensive Small Cell Lung Cancer Cadonilimab+EC/ET+RT Cadonilimab+vorolanib 70 Henan Cancer Hospital Zhengzhou Henan 450000 China NCT06406660 Henan Cancer Hospital Patient-derived Organoid Drug Sensitivity Guided Treatment for Recurrent Small Cell Lung Cancer April 16, 2024 Small Cell Lung Cancer Chemotherapy and targeted-therapy guided by organoid drug sensitivity test 20 Henan Cancer Hospital Zhengzhou Henan 450003 China NCT06406647 New Valley University Rectroclavicular Block in Orthopedic Surgey June 1, 2024 Numerical Rating Pain Scale retrocalvicular block 80 NCT06406634 Hunan Cancer Hospital Cadonilimab in Combination With Lenvatinib and Hepatic Arterial Infusion Chemotherapy (HAIC) for the Treatment of Unresectable Hepatocellular Carcinoma May 15, 2024 Hepatocellular Carcinoma Cadonilimab Lenvatinib Hepatic Arterial Infusion Chemotherapy (HAIC) Unresectable Hepatocellular Carcinoma Cadonilimab Lenvatinib 30 Hunan Cancer Hospital Changsha Hunan 410013 China NCT06406621 Nemours Children's Clinic Pilot RCT Laser Hair Depilation Darker Skin Pilonidal Disease March 2025 Pilonidal Disease Pilonidal Sinus Pilonidal Abscess Pilonidal Cyst/Fistula laser hair depilation pilonidal Laser hair depilation 36 NCT06406608 Henan Cancer Hospital Patient-derived Organoid Drug Sensitivity Guided Treatment for Drug-resistant Recurrent Non-Small Cell Lung Cancer April 16, 2024 Non-small Cell Lung Cancer Chemotherapy and targeted-therapy guided by organoid drug sensitivity test 20 Henan Cancer Hospital Zhengzhou Henan 450003 China NCT06406595 University of Alberta Hemispheric Asymmetries in Emotion-Cognition Interactions September 1, 2024 Anxiety Depression Disorder 60 NCT06406582 Hanoi Medical University Treatment Result of Zirconia Laminate Veneer September 25, 2023 Dislocation, Tooth Teeth, Endodontically-Treated Tooth Fracture Tooth Injuries Tooth Abnormalities Cracked Tooth Syndrome Tooth Crowding ceramic laminate veneers zirconia lithium disilicate computer-aided manufacturing Zirconia laminate veneer Lithium Disilicate laminate veneer 50 High Technical Center of Dentistry, School of Dentistry Hanoi 10000 Vietnam NCT06406569 Tan Tock Seng Hospital A Qualitative and Usability Evaluation of Advanced Technologies for Home Upper Limb Neurorehabilitation Post-stroke June 2024 Stroke Technology-aided Upper limb rehabilitation H-Man Robot ReHandyBot MyoPanda 30 NCT06406556 Sun Yat-sen University Safety & Efficacy of Peg-ASP-based CCRT in Early Stage ENKTL March 1, 2016 Extranodal NK/T-cell Lymphoma extranodal NK/T-cell lymphoma concurrent chemoradiotherapy pegaspargase Pegaspargase combined with concurrent radiotherapy. 90 HuaWang Guangzhou Guangdong 510060 China NCT06406543 Columbia University Vitamin D in Armenia: Vitamin D Repletion Strategies With Dibase, and Vitamin D and Vitamin D Binding Protein and COVID December 1, 2023 Vitamin D Deficiency Vitamin D repletion Vitamin D3 (Cholecalciferol) 77 Osteoporosis Center of Armenia Yerevan Armenia NCT06406530 University of Giessen Topical Application of PRF Before Radiation Therapy December 1, 2023 PRF PRF wound healing dentistry oral surgery radiation therapy cancer PRF Natural Healing 34 University of Giessen Gießen Hessen Germany NCT06406517 University of California, San Diego Comparative Effectiveness of Gadopiclenol for Evaluation of Adult Congenital Heart Anatomy and Hemodynamics May 2024 Congenital Heart Disease Gadopiclenol Gadobenate dimeglumine 160 University of California San Diego Health San Diego California 92037 United States NCT06406504 Mehmet Akif Ersoy University Improving Pressure Injury Classification and Assessment Skills: In Situ Simulation and Moulage September 1, 2021 Pressure Injury In-situ simulation simulation-based training moulage pressure injury nursing students in-laboratory simulation group in-situ simulation group 84 Mehmet Akif Ersoy University Burdur Turkey NCT06406491 Median Passive Microprocessor-controlled Knees vs. Active Microprocessor-controlled Knees After Transfemoral Amputation April 23, 2024 Amputation transfemoral amputation prosthetic user microprocessor-controlled knee functional outcomes patient-reported outcomes active microprocessor-controlled knee 10 MEDIAN Clinics Wiesbaden Germany NCT06406478 University of California, Los Angeles Work Time Schedule Changes for Nurse Managers May 2024 Work-Related Condition Schedule Change No Schedule Change 50 Ronald Reagan UCLA Medical Center UCLA Health, Santa Monica Los Angeles Santa Monica California California 90095 90404 United States United States NCT06406465 National Institutes of Health Clinical Center (CC) A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity May 19, 2024 Carcinoma, Neuroendocrine Tumor, Neuroendocrine Tumors, Neuroendocrine Neuroendocrine; Carcinoma Small Cell; Receptors High-grade carcinomas Resemble small cell carcinoma Large cell NEC Histone Deacetylase Genotypes Neuroendocrine malignancies Belinostat Cisplatin Etoposide 60 National Institutes of Health Clinical Center Bethesda Maryland 20892 United States NCT06406452 University of Michigan Bioresorbable Airway Splint Pivotal Clinical Trial May 2024 Tracheobronchomalacia Children Airway splint Three-dimensional printed Multi-stie Bioresorbable Tracheobronchial Splint 35 University of Michigan Ann Arbor Michigan 48109 United States NCT06406439 G2e Co., Ltd DIA:CONN P8(Smart Insulin Pen) Study in Diabetes Patients May 9, 2024 Diabetes Mellitus Smart Insulin Pen 120 Samsung Medical Center Seoul Gangnam-gu 135710 Korea, Republic of NCT06406426 Fudan University Study of The Second-line Treatment of Advanced Gastric / Gastroesophageal Junction Adenocarcinoma With Cadonilimab and Fruquintinib Combined With Paclitaxel-albumin May 1, 2024 Gastric / Gastroesophageal Junction Adenocarcinoma Cadonilimab and Fruquintinib Combined With Paclitaxel-albumin 40 Fudan University Shanghai Cancer Center Shanghai Shanghai 200032 China NCT06406413 First Affiliated Hospital of Zhejiang University Micro-movements in Patients With Prolonged Disorders of Consciousness May 1, 2024 Consciousness Disorders disorders of consciousness consciousness disorders micro-movement consciousness Multidimensional paradigm stimulation micro-movement; electroencephalogram; MRI 179 First Affiliated Hospital,Zhejiang University Hanzhou Zhejiang 310003 China NCT06406400 AstraZeneca Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2). May 7, 2024 Opioid Use Disorder Drug-drug interactions Adjunctive treatment Itraconazole Buprenorphine Naloxone Pharmacokinetics AZD4041 Itraconazole Buprenorphine Buprenorphine / Naloxone Hydromorphone Placebo 100 Research Site Baltimore Maryland 21225 United States NCT06406387 Azienda Ospedaliera Universitaria Integrata Verona ATRX/DAXX in EUS-FNB Specimens of Pan-NETs May 6, 2024 Pancreatic Neuroendocrine Tumor ATRX/DAXX immunohistochemistry 100 NCT06406374 A.O.U. Città della Salute e della Scienza Italian Translation and Validation of the Non-Motor Fluctuation Assessment (NoMoFA) Questionnaire: an Observational, Multicentric, Cross-sectional, 6-months Duration Study on 200 Consecutive Parkinson's Disease Patients. April 26, 2023 Parkinson's Disease Parkinson's disease Non-motor fluctuations NoMoFA 200 Dipartimento di Neuroscienze e Salute Mentale SC Neurologia 2U Torino TO 10126 Italy NCT06406361 Amasya University The Effect of Stress Management Training Applied to Nurses May 14, 2024 Stress Management Workplace Stress Nursing stress management workload perception stress nursing nursing education stress management training 28 NCT06406348 Aliada Therapeutics A Phase 1 Trial to Assess Safety, Tolerability and Pharmacokinetics of ALIA-1758 in Healthy Participants May 2024 Alzheimer Disease ALIA-1758 Placebo 52 Worldwide Clinical Trials Early Phase Services, LLC San Antonio Texas 78217 United States NCT06406335 Ain Shams University Impact of A Multidimensional Health Education Program on Attention Deficit Hyperactivity Disorder (ADHD) February 23, 2024 ADHD ADHD Health education program 63 faculty of medicine Ain shams university Cairo 1181 Egypt NCT06406322 Atılım University Pelvic Floor Dysfunction and Aerobic Training in Gynecological Cancer June 1, 2024 Gynecologic Cancer Pelvic Floor Disorders Aerobic Exercise Pelvic Floor Dysfunction Gynecologic Cancer Physiotherapy PFMT Aerobic Exercise 40 NCT06406309 University of Pittsburgh Settling Down for Sleep in ADHD: The Impact of Sensory and Arousal Systems on Sleep in ADHD September 2024 Attention Deficit Hyperactivity Disorder Sleep Disturbance Sleep disturbances Emotion Dysregulation Sensory Processing ADHD Power Down manipulation 30 NCT06406296 Universidad Europea de Madrid Effectiveness of ACT for Problematic Chemsex June 1, 2024 Hypersexuality Compulsive Sexual Behavior Sexualized Drug Use (Chemsex) Sexuality Risky sexual behavior Acceptance and Commitment Therapy (ACT) 22 Universidad Europea de Madrid Villaviciosa De Odón Madrid 28670 Spain NCT06406283 University of Barcelona Active Young, Healthy Mind. The YoungFitT Project December 20, 2023 University Students Well-being Physical exercise Qigong Mindfulness Neuroimaging Intervention Randomization Cognition Virtual environment High-Intensity Functional Training (HIFT) Mindfulness-Based Stress Reduction Program (MBSR) Qigong 219 Maria Mataro Barcelona Spain NCT06406270 University of Aberdeen Alternative Protein Short Chronic Study June 6, 2014 Healthy Fava Buckwheat 20 NCT06406257 Second People's Hospital of Hefei City Temperature Management on Postoperative Delirium May 20, 2024 Emergence Delirium Postoperative Delirium Body Temperature Hyperthermia Hypothermia 3M™ Bair Hugger™ Warming Unit 150 NCT06406244 West China Hospital Efficacy of TEAS on Chronic Pain and Survival in Patients Undergoing Hepatectomy April 20, 2024 Liver Cancer TEAS group sham group 524 West China Hospital Chengdu 610041 China NCT06406231 University Tunis El Manar Magnetic Field Therapy Versus Transcutaneous Electrical Nerve-stimulation in Knee Osteoarthritis September 15, 2023 Knee Osteoarthritis comparing efficacy of TENS and PEMF in knee osteoarthritis 60 Military Hospital of Tunis Tunis 1008 Tunisia NCT06406218 Shenyang Northern Hospital The Impact of Phase I Cardiac Rehabilitation on the Prognosis of AMI Patients After PCI April 24, 2024 Acute Myocardial Infarction Phase I Cardiac Rehabilitation Phase I Cardiac Rehabilitation Exercise Training 1100 General Hospital of Northern Theater Command Shenyang Liaoning 110016 China NCT06406205 Qilu Pharmaceutical Co., Ltd. A Study of QLG1074 Combined With Background Therapy in Subjects With Active Lupus Nephritis December 25, 2023 Lupus Nephritis Voclosporin（QL1074） Placebo 270 The First Affiliated Hospital of Bengbu Medical University The People's Hospital of Bozhou Anhui Provincial Hospital The Second Affiliated Hospital of Anhui Medical University Chincse PLA General Hosptial Peking University First Hospital Fujian Medical University Union Hospital The First Affiliated Hospital of Dalian Medical University Huashan Hospital Heping Hospital Affiliated to Changzhi Medical College Bengbu Bozhou Hefei Hefei Beijing Beijing Fuzhou Dalian Shanghai Changzhi Anhui Anhui Anhui Anhui Beijing Beijing Fujian Liaoning Shanghai Shanxi China China China China China China China China China China NCT06406192 National Taiwan University Hospital Effects of FOR-Care Model on Preventive Medicine March 11, 2024 Diabetes Mellitus Body Weight Family Medicine Hypertension Preventive Medicine Body weight Diabetes mellitus Cluster randomized trial Family medicine Outpatient department Preventive medicine Height, Weight, and Blood Pressure Measurement Procedures Improvement 800 National Taiwan University Hospital Taipei 100 Taiwan NCT06406179 Assistance Publique - Hôpitaux de Paris Assesment the Efficacy of Dd-cfDNA in Routine Patient Care in Kidney Transplant Recipients" June 1, 2024 Renal Transplantation renal transplantation rejection non-invasive biomarker (dd-cfDNA ) risk evaluation randomized trial Gene expression dd-cfDNA-guided 500 Hopital Saint Louis Georges Pompidou European Hospital Hôpital Necker-Enfants Malades AP-HP - Hôpital Tenon CHU Toulouse Paris Paris Paris Paris Toulouse Ile De France 75010 75015 75015 France France France France France NCT06406166 Henan University of Traditional Chinese Medicine Lifei Xiaoji Wan in Treatment of Advanced NSCLC June 1, 2022 Advanced Non Small Cell Lung Cancer advanced non small cell lung cancer traditional Chinese medicine randomized controlled trial Lifei Xiaoji Wan Conventional treatment with Western medicine 100 the First Affiliated Hospital of Henan University of Chinese Medicine Zhengzhou Henan 450000 China NCT06406153 Cinnagen Efficacy and Safety of P046 (Laronidase-CinnaGen) Compared to Aldurazyme® in MPS I Patients September 10, 2022 Mucopolysaccharidosis Type 1 Urinary Glycosaminoglycans Laronidase Mucopolysaccharidosis type I Aldurazyme® Laronidase Antihistamine Antipyretic 12 Clinical Research Development Unit of Akbar Hospital, Faculty of Medicine Growth and Development Research Center, Childrens Medical Center Loghman Hospital Mofid Childrens Hospital Mashhad Tehran Tehran Tehran Iran, Islamic Republic of Iran, Islamic Republic of Iran, Islamic Republic of Iran, Islamic Republic of NCT06406140 Al-Azhar University Study the Effect of Niacin on Lipoprotein (a) Concentration and Hyperphosphatemia in Hemodialysis Patients March 15, 2024 End-stage Renal Disease Hemodialysis Niacin Lipoprotein a Niacin tablets 500 mg 50 Al Azhar University Cairo Egypt NCT06406127 Ain Shams University Effect of Alpha Lipoic Acid on Chemotherapy Induced Neurological Changes in Breast Cancer Patients April 1, 2024 Breast Cancer Alpha Lipoic Acid Paclitaxel Neurologic Disorder Chemotherapy Alpha Lipoic Acid 600 MG Oral Capsule 92 Dar El Salam Cancer Hospital (Harmel Hospital) Cairo El Malek El Saleh 11559 Egypt NCT06406114 Massachusetts General Hospital Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing August 1, 2024 Drug Allergy Cephalosporin Allergy Drug Hypersensitivity Antibiotic Allergy Beta Lactam Adverse Reaction Drug-Induced Anaphylaxis Cephalosporin Reaction Allergy Antibiotic Cephalosporin Penicillin Beta-lactam Drug challenge Skin testing Adverse reaction Anaphylaxis Perioperative anaphylaxis Beta-lactam antibiotic (cefazolin, cefuroxime, cefotaxime, ceftazidime, ceftriaxone, cefepime, pre-pen, penicillin G, ampicillin, and histamine) double-blind skin testing Culprit cephalosporin (cefazolin, ceftazidime, ceftriaxone, cefepime, cephalexin, cefaclor, cefadroxil, cefuroxime, cefpodoxime, cefdinir, or cefixime) double-blind placebo-controlled drug challenge Similar cephalosporin (cefepime, ceftriaxone, cefaclor, cephalexin, cefixime, or cefdinir) antibiotic double-blind placebo-controlled drug challenge Dissimilar cephalosporin (ceftriaxone or cefazolin) antibiotic double-blind placebo-controlled drug challenge Amoxicillin double-blind placebo-controlled drug challenge 300 Mayo Clinic Arizona University of California, San Francisco Rochester General Hospital Vanderbilt University Medical Center University of Texas Southwestern Medical Center Scottsdale San Francisco Rochester Nashville Dallas Arizona California New York Tennessee Texas 14607 94143 14621 37232 75390 United States United States United States United States United States NCT06406101 Hospital Clinic of Barcelona CPR Surface Choice on Chest Compression Quality May 8, 2024 Cardiac Arrest Simulation of Physical Illness Cardiopulmonary Resuscitation Cardiac arrest Simulation study Chest Compressions Floor Bed 147 Hospital Clinic Barcelona Barcelona 08036 Spain NCT06406088 The Bionics Institute of Australia EarGenie MVP Performance Evaluation June 15, 2024 Hearing Impaired Children fNIRS EarGenie MVP test 50 Bionics Institute East Melbourne Victoria 3002 Australia NCT06406075 Spiden AG Non-invasive Measurement of Glucose With Advanced Spectroscopy Techniques and Machine Learning Models January 29, 2024 Healthy Continuous glucose monitoring Noninvasive Transcutaneous Lab demo 1.0 81 Spiden AG Pfäffikon Schwyz 8808 Switzerland NCT06406062 Renmin Hospital of Wuhan University Artificial Intelligence-assisted System in Colonoscopy May 20, 2024 Adenoma Colon Polyp ANDOANGEL 20000 Renmin Hospital of Wuhan Univercity Wuhan Hubei 430060 China NCT06406049 University of Miami Finishing HIV Project December 15, 2024 Hiv Control group Social network intervention 624 University of Miami Miami Florida 33136 United States NCT06406036 Riphah International University A Validity and Reliability Study for Urdu Version of Rivermead Mobility Index in Stroke Patients May 30, 2021 Stroke Rivermead Mobility Index Urdu Version Reliability Validity Stroke Mobility 50 Ripah International University Faisalabad Punjab 38000 Pakistan NCT06406023 Riphah International University Effectiveness of Instrument Assisted Soft Tissue Mobilization in Management of Piriformis Syndrome January 10, 2024 Piriformis Syndrome Conventional treatment Instrument assisted soft tissue mobilization 38 Railway General Hospital Rawalpindi Punjab Pakistan NCT06406010 Rigshospitalet, Denmark Investigating the Effect of Pericapsular Nerve Group (PENG) Block on Postoperative Pain After Peri-acetabular Osteotomy June 1, 2024 Anesthesia, Local Ropivacaine 5mg/ml 20ml Saline 0.9% 90 Rigshospitalet Copenhagen 2100 Denmark NCT06405997 National Taiwan University Hospital The Genotype and Phenotype of Lymphangioleiomyomatosis May 10, 2024 Sporadic Lymphangioleiomyomatosis TSC-associated Lymphangioleiomyomatosis Lymphangioleiomyomatosis 100 National Taiwan University Hospital Taipei Taiwan NCT06405984 Raydiant Oximetry, Inc. Trans-Abdominal Fetal Pulse Oximetry - EFS-IDE April 15, 2024 Fetal Hypoxia Fetal Distress Fetal Conditions Fetal Complications Labor Fetal Anoxia Labor (Obstetrics)--Complications Oxygen Deficiency fetal hypoxia fetal distress oxygen deficiency labor fetal anoxia Fetal Oxygenation Measurements 10 Sentara Norfolk General - Eastern Virginia Medical School Norfolk Virginia 23510 United States NCT06405971 Beijing Tiantan Hospital Metformin in Patients With Unruptured Vertebrobasilar Dissecting Aneurysms (METTLE) June 1, 2024 Dissecting Aneurysm of Cerebral Artery Vertebrobasilar dissecting aneurysms Metformin High-resolution vessel wall imaging Inflammatory reaction Metformin 60 NCT06405958 Asan Medical Center Gut Microbiome Analysis in Organ Transplant Recipient May 1, 2024 Microbial Colonization microbiota solid organ transplantation metagenomic sequencing gut microbiome 200 NCT06405945 Anhui Provincial Hospital Cervical Cancer Susceptible Population Classification May 1, 2024 Cervical Cancer Susceptible Population Classification PCR and sequence 10000 The First Affiliated Hospital of USTC Hefei Anhui 230001 China NCT06405932 Anhui Medical University Study of the Intervention Effect of Self-help Training Camps in Promoting Mental Health Among Perinatal Women May 20, 2024 Mental Health Perinatal Depression Mental Fitness Training Camp 500 NCT06405919 University of Khartoum Risk of Malignancy in Endemic Long Standing Nodular Goitres: a Prospective Cohort Study March 1, 2017 Incidence of Thyroid Cancer in Long Standing MNG : goitre, long standing, malignant risk, incidental. Histopathology 160 Faculty of Medicine University of Khartoum Khartoum 11111 Sudan NCT06405906 University Hospital of Crete A Randomized Controlled Trial Comparing Fat-free Versus Balanced (WHO) Diet in Gallstone Disease March 27, 2024 Gallstone Disease Gallstone; Colic Gallstone; Cholecystitis, Acute Cholelithiases Postcholecystectomy Syndrome Dietary Habits gallstone disease cholecystitis cholecystectomy gallbladder diet Fat-free diet Balanced WHO diet 242 Department of Surgery, University Hospital of Heraklion Heraklion 71110 Greece NCT06405893 University of Colorado, Colorado Springs What Makes People Better at Naming Pictured Objects April 4, 2024 Healthy Aging Aging; Mindfulness; Speech Production Mindful breathing exercise 200 UCCS Colorado Springs Colorado 80918 United States NCT06405880 University of Alberta Pharmacist Case Finding and Intervention for Vascular Prevention Trial September 2024 Cardiovascular Risk Factors Blood Pressure Cardiovascular Disease Diabetes Dyslipidemia cardiovascular blood pressure diabetes dyslipidemia Pharmacist-led care pathway 982 NCT06405867 Goztepe Prof Dr Suleyman Yalcın City Hospital The Importance of Delayed Cord Clamping June 1, 2020 Newborn; Vitality Iron Deficiency Anemia Delayed cord clamping hypothermia polycythemia iron deficiency anemia delayed cord clamping (> 60 sec) 316 Goztepe Prof Dr. Suleyman Yalcın City Hospital Istanbul N/A (n/a) 34730 Turkey NCT06405854 Princess Nourah Bint Abdulrahman University Coordination-based Exercise Intervention in Preschool Children September 12, 2022 Motor Skills Balance Fitness Preschool Exercise 44 Monira Aldhahi Riyadh 12341 Saudi Arabia NCT06405841 Ospedali Riuniti Trieste Costal Fracture Assessment for Relief and Enhancement of Quality of Life June 2024 Rib Fractures Rib Trauma Survey Pain management 950 Department of General Surgery Department of Thoracic Surgery Emergency Department Intensive Care Unit Trieste Trieste Trieste Trieste TS TS 34149 34149 34149 34149 Italy Italy Italy Italy NCT06405828 Icahn School of Medicine at Mount Sinai Enhancing Access to Supportive Services for Women of Color With Metastatic Breast Cancer May 2024 Metastatic Breast Cancer Stage IV Breast Cancer AJCC V7 ACCESS Supportive Care Phone sessions 60 NCT06405815 Jinling Hospital, China A Radiomic Model for Risk of Local Recurrence and DFS for T3 and T4 Non-small Cell Lung Cancer January 1, 2021 Lung Cancer, Nonsmall Cell non-small cell lung cancer surgical margin DFS radiomics tumor and peritumor radiomic feature 200 Jinling Hospital Nanjing Jiangsu China NCT06405802 Izmir Katip Celebi University Comparison of Technology-assisted and Face-to-face Assessment in Patients With Low Back Pain August 10, 2022 Low Back Pain tele-evaluation Low Back Pain Face to face evaluation Tele-evaluation 50 Izmir Kâtip Çelebi University Vocational School of Health Services İzmir Turkey NCT06405789 Izmir Democracy University The Effect of Yoga on Mindfulness and Perceived Stress September 30, 2019 Stress yoga mindfulness yoga practice 56 İzmir Democracy University İzmir Ege Bölgesi 35560 Turkey NCT06405776 West China Hospital Effect of Lidocaine on Postoperative Pain and Long-term Survival in Elderly Patients Undergoing Colorectal Surgery June 5, 2023 Colorectal Cancer lidocaine Placebo 276 China Sichuan China NCT06405763 Sohag University Snodgrass Versus Grafted Snodgrass Repair in Narrow Urethral Plate in Distal Penile Hypospadias December 11, 2023 Hypospadias Snodgrass repair Snodgrass repair with graft 50 Sohag University Hospitals Sohag 82511 Egypt NCT06405750 University Hospital Bispebjerg and Frederiksberg Left Atrial Appendage Arrhythmogenic and Thrombogenic Substrate May 15, 2024 Atrial Fibrillation Stroke heart surgery atrial myocardiopathy arrhythmogenic substrate stroke cerebral transitory ischemic attack thrombogenesis cardiac embolism left atrial appendage closure 1000 NCT06405737 University of Electronic Science and Technology of China Oxytocin's Effect on the Advantageous- and Disadvantageous-inequity January 7, 2024 Healthy advantageous inequity disadvantageous inequity fMRI oxytocin Intranasal oxytocin Intranasal placebo 80 University of Electronic Science and Technology of China (UESTC) Chengdu Sichuan 611731 China NCT06405724 Tongji Hospital Comparison of the Ultrasound-guided Paravertebral Nerve Block With Liposomal Bupivacaine Versus Ropivacaine for Post-Surgical Pain After Video-Assisted Thoracoscopic Surgery May 10, 2024 Analgesia paravertebral nerve block liposomal bupivacaine video-assisted thoracoscopic surgery Liposomal bupivacaine Ropivacaine 84 Tongji Hospital Wuhan Hubei 430030 China NCT06405711 Tianjin Eye Hospital To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia May 2024 Myopia, Progressive myopia axial length defocus frame lens 138 Tianjin Eye Hospital Tianjin China NCT06405698 Assiut University Role of Perforator Flaps in Back Defects Reconstruction May 2024 Myelomeningocele myelomeningocele perforator flaps infants surgical closure of myelomeningocele defects by perforator flaps surgical closure of myelomeningocele defects by perforator-plus flaps 30 NCT06405685 Tianjin Medical University Cancer Institute and Hospital Nimotuzumab Plus AG in Pancreatic Cancer With Liver Metastasis April 27, 2023 Pancreatic Cancer Nimotuzumab AG 30 Tianjin Medical University Cancer Institute and Hospital Tianjin China NCT06405672 Antalya Training and Research Hospital The Effect of Endotracheal Tube With Stylet in Morbidly Obese Patients April 30, 2024 Intubation; Difficult or Failed Obesity, Morbid different intubation techniques endotracheal tube obesity stylet Endotracheal tube with stylet Endotracheal tube alone 80 NCT06405659 Affiliated Hospital of Guangdong Medical University Immediate Fever During Anaesthesia Recovery After Surgical Procedure With Scoliosis August 6, 2018 Fever Scoliosis Surgical Trauma Hypothermia General Anaesthesia correction for pedicle fixation 1 The Affiliated Hospital of Guangdong Medical University Zhanjiang Guangdong China NCT06405646 Wroclaw Medical University Concentration of Receptors With Affinity for Cannabidiol and Cannabinol and the Effect on Chronic Orofacial Pain of Muscle Origin June 2024 Myalgia Muscle Pain Orofacial Pain Headache, Tension Headaches Muscular cannabidiol cannabinol TRPV1 receptor CB1 receptor CB2 receptor Blood CB1, CB2, TRPV-1 concentration measurement 102 Wroclaw Medical University Wroclaw 50-425 Poland NCT06405633 Wave Life Sciences Ltd. A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD June 2024 Alpha-1 Antitrypsin Deficiency WVE-006 24 NCT06405620 University Hospital, Toulouse Use of a Social Assistance Robot in a Population of Children Subjected to Prolonged Isolation June 1, 2024 Social Isolation Assistance robot 33 NCT06405607 University of Iowa Psilocybin vs Ketamine for Alcohol Use Disorder June 2024 Alcohol Use Disorder Alcohol Dependence Alcohol Abuse psychedelic psilocybin ketamine Psilocybin Ketamine 80 NCT06405594 University of Maryland, College Park Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia June 2024 Aphasia, Acquired Stroke Healthy Aging Language Condition 350 NCT06405581 Umraniye Education and Research Hospital The Impact of Frailty on Cardiopulmonary Resuscitation Adverse Outcomes in Patients Requiring Code Blue Activation December 1, 2023 Cardiac Arrest Frailty Respiratory Arrest Edmonton frailty scale calculation 2 Umraniye Education and Research Hospital Umraniye Education and Research Hospital Istanbul Istanbul Umraniye Umraniye 34734 34734 Turkey Turkey NCT06405568 University of Ottawa Physical Activity for Adults in the Ontario Breast Screening Program June 1, 2024 Breast Cancer Female Physical Inactivity Healthcare providers Physical activity Breast cancer Physical activity intervention 200 NCT06405555 Ottawa Heart Institute Research Corporation Midodrine in Heart Failure With Reduced Ejection Fraction With Hypotension August 1, 2024 Heart Failure With Reduced Ejection Fraction Hypotension LV Dysfunction Heart Failure GDMT Midodrine Midodrine Oral Tablet 56 NCT06405542 University Health Network, Toronto Exercise-based Rehabilitation to Treat Persistent Chemotherapy Induced Peripheral Neuropathy (CIPN) April 25, 2024 Chemotherapy-induced Peripheral Neuropathy Cancer Rehabilitation Peripheral Neuropathy EX-CIPN 40 ELLICSR: Health Wellness and Cancer Survivorship Centre Toronto Ontario M5G 2N2 Canada NCT06405529 University of Sao Paulo Rehabilitation of Patients From the ICU to the Post-hospital Phase July 1, 2024 Early Mobilization Physiotherapy Rehabilitation Mechanical ventilation Physiotherapy Respiratory function Functional capacity Rehabilitation Cost-effectiveness Early and intensive mobilization protocol at the ICU and Rehabilitation post-hospital discharge 206 NCT06405516 Insel Gruppe AG, University Hospital Bern Platelet Function After Cardiac Surgery. May 1, 2024 Platelet Dysfunction Autologous blood cell salvage with in-house device Autologous cell salvage with i-Sep SAME device 40 Department of Anesthesiology and Pain Medicine Bern 3010 Switzerland NCT06405503 University of Texas at Austin Impact of Primary Language on Treatment and Outcomes in Inflammatory Bowel Disease June 1, 2024 Inflammatory Bowel Disease NO INTERVENTION 206 Dell Medical School at the University of Texas at Austin Austin Texas 78712 United States NCT06405490 Cancer Institute and Hospital, Chinese Academy of Medical Sciences NALIRI-XELOX+AK104 for First-line Treatment of Advanced PDAC April 17, 2024 Nanoliposomal Irinotecan Cadonilimab Oxaliplatin Capecitabine First-Line Advanced Cancer Pancreatic Adenocarcinoma Drug Use Pancreatic Adenocarcinoma Nanoliposomal Irinotecan Cadonilimab First-Line Treatment Advanced Pancreatic Adenocarcinoma Nanoliposomal Irinotecan+Oxaliplatin +Capecitabine+Cadonilimab 30 Cancer Institute and Hospital, Chinese Academy of Medical Sciences Beijing Beijing China NCT06405477 Universidade Estadual Paulista Júlio de Mesquita Filho EFFECTS OF L-ARGININE SUPPLEMENTATION ON THE RECOVERY OF CARDIORESPIRATORY PARAMETERS AFTER SUBMAXIMAL EXERCISE TEST February 15, 2024 Nutrition, Healthy L-arginine Placebo 35 UNESP Presidente Prudente SP 19060-900 Brazil NCT06405464 University of Zurich Cabotegravir Plus Rilpivirine Long-acting Regimen in the Swiss HIV Cohort Study:Uptake, Outcome, and Risk Factors for Treatment Failures March 1, 2022 HIV Infections VOCABRIA 30Mg Tablet EDURANT 25Mg Tablet Cabotegravir Injectable Suspension Rilpivirine Injectable Suspension Intact proviral DNA assay Full-length sequencing 600 University Hospital Zurich Zurich 8091 Switzerland NCT06405451 Universidad Europea de Madrid Respiratory Muscle Training Program in Patients With Multiple Sclerosis January 10, 2024 Multiple Sclerosis Respiration Disorders multiple sclerosis treatment trunk disorder balance respiratory function Conventional treatment Experimental treatment 20 Universidad Europea de Madrid Villaviciosa De Odón Madrid 28670 Spain NCT06405438 Beylikduzu State Hospital Comparison of the Efficacy of Peloid Therapy and Paraffin Treatment in Carpal Tunnel Syndrome June 1, 2024 Carpal Tunnel Syndrome carpal tunnel syndrome median neuropathy median nerve peloid therapy mud therapy physical therapy 60 Beylikdüzü State Hospital Istanbul 34147 Turkey NCT06405425 Sichuan Baili Pharmaceutical Co., Ltd. A Study of BL-B01D1 + PD-1 in Patients With Locally Advanced or Metastatic Urothelial Carcinoma May 2024 Urothelial Carcinoma BL-B01D1 PD-1 52 Fudan University Shanghai Cancer Center Shanghai Shanghai China NCT06405412 Umraniye Education and Research Hospital Effects of Malnutrition on Respiratory and Renal Functions in Patients Undergoing Peroral Endoscopic Myotomy (POEM) November 1, 2023 Achalasia achalasia Peroral Endoscopic Myotomy MUST malnutrition score 50 Umraniye Education and Research hospital Istanbul 34764 Turkey NCT06405399 Clinica Universidad de Navarra, Universidad de Navarra Design, Implementation and Evaluation of the Guided Observer Role in Clinical Simulation May 10, 2023 Anaphylactic Reaction simulation training; undergraduated students Educational intervention. observation guide 123 University of Navarra Pamplona Navarra 31003 Spain NCT06405386 University of North Carolina, Chapel Hill Pilot of Pragmatic Delivery of Behavioral Approaches to Reduce Diabetes Distress in Adults With Type 1 Diabetes May 2024 Diabetes type1 Diabetes Mellitus, Type 1 Diabetes, Autoimmune Diabetes Mellitus Distress, Emotional Diabetes Type 1 diabetes Diabetes distress T1D Emotional distress Telehealth SMART design ReCharge TakeCharge 15 University of North Carolina at Chapel Hill Chapel Hill North Carolina 27599 United States NCT06405373 University of North Carolina, Chapel Hill Pragmatic Delivery of Behavioral Approaches to Reduce Diabetes Distress in Adults With Type 1 Diabetes May 2024 Diabetes type1 Diabetes Mellitus, Type 1 Diabetes, Autoimmune Diabetes Mellitus Distress, Emotional Diabetes Type 1 diabetes Diabetes distress T1D Emotional distress Telehealth SMART design ReCharge TakeCharge 200 University of North Carolina at Chapel Hill Chapel Hill North Carolina 27599 United States NCT06405360 University of Florida DEUX OEUFs: Cracking the Potential of Eggs to Improve Child Growth and Development May 2, 2024 Infant Malnutrition Fetal Growth Retardation Nutrition Maternal Health Infant growth and development Maternal diet Egg consumption 1912 Ndama Health Center Nyagatare Rwanda NCT06405347 University of Michigan The M-Well Inpatient Whole Health Bundle May 2024 Patient Satisfaction Holistic Health Mindfulness Hospitalization Inpatient Whole Health Bundle 900 VA Ann Arbor Healthcare System Ann Arbor Michigan 48105 United States NCT06405334 VA Office of Research and Development Kinematic and Neural Dynamics of Postural Instability in Parkinson's Disease July 1, 2024 Parkinson's Disease Parkinson Disease subthalamic nucleus gait postural instability deep learning 100 Minneapolis VA Health Care System, Minneapolis, MN Minneapolis Minnesota 55417-2309 United States NCT06405321 Guangxi Medical University Conversion or Neoadjuvant Therapy in Hepatocellular Carcinoma January 1, 2019 Hepatocellular Carcinoma conversion therapy neoadjuvant therapy Conversion or neoadjuvant therapy. 2000 Jian-Hong Zhong Nanning 530021 China NCT06405308 The First Affiliated Hospital of Nanchang University Robotic Natural Orifice Specimen Extraction Surgery Versus Robotic Transabdominal Specimen Extraction Surgery for Early-Stage Rectal Cancer October 1, 2023 Rectal Cancer Robotic Surgery Natural Orifice Specimen Extraction Surgery R-NOSES group R-TSES group 636 The Second Xiangya Hospital of Central South University Cancer Institute and Hospital, Chinese Academy of Medical Sciences Three Gorges Hospital Affiliated to Chongqing University Fujian Cancer Hospital The Second Affiliated Hospital of Harbin Medical University The First Affiliated Hospital of Nanchang University Zhongshan Hospital, Fudan University The First Affiliated Hospital of Zhengzhou University Changsha Beijing Chongqing Fuzhou Harbin Nanchang Shanghai Zhengzhou Hunan 410008 China China China China China China China China NCT06405295 Cancer Institute and Hospital, Chinese Academy of Medical Sciences A Multicentre Prospective Cohort Study: Intensive Adjuvant Therapy for TNBC With BRCA Gene Mutation May 6, 2024 Early-stage Triple-negative Breast Cancer With BRCA1/2 Mutations no intervention 600 Cancer Hospital, Chinese Academy of Medical Sciences Beijing Beijing 100021 China NCT06405282 Nova Southeastern University Weightlessness Associated Cephalad Fluid Shifts; The Potential to Evaluate Venous and Lymphatic Dysfunction April 14, 2022 Fluid Retention Tissue Perfusion; Complications dermal flow venous flow fluid shift manual lymphatic drainage blood circulation space simulation diagnostic imaging tissue temperature gradient Manual Lymphatic Drainage Near infrared spectroscopy Temperature Tissue Dialectic Constant 15 Nova Southeastern University Fort Lauderdale Florida 33328 United States NCT06405269 Cancer Institute and Hospital, Chinese Academy of Medical Sciences A Multicentre Prospective Cohort Study: Effect of (Neo)Adjuvant Therapy on Lipids in Young Breast Cancer Patients May 6, 2024 Young Breast Cancer Patient Lipids Anti-tumour Drug Therapy 600 NCT06405256 Cancer Institute and Hospital, Chinese Academy of Medical Sciences Magnetic Resonance Imaging-guided Adaptive Radiotherapy for Large Brain Metastases January 3, 2020 Brain Metastases Magnetic Resonance Imaging-guided Adaptive Radiotherapy magnetic resonance imaging-guided adaptive radiotherapy 20 Chinese Academy of Medical Science and Peking Union Medical College Beijing China NCT06405243 Beni-Suef University Myoinositol, L-arginine and Chromium With Letrozole for Ovulation Induction in Polycystic Ovarian Syndrome Patients June 30, 2024 Polycystic Ovary Syndrome Polycystic Ovary Syndrome letrazole myoinositol L-arginine Chromium Myoinositol Chromium l-arginine Letrozole 2.5mg 100 Beni-suef university Hospital Beni-suef university Banī Suwayf Banī Suwayf 62511 62511 Egypt Egypt NCT06405230 GlaxoSmithKline Evaluation of Programmed Death Ligand 1 (PDL1) Response to Treatment in Patient-derived Organoids and Immune-marker Positron Emission Tomography (PET) Scanning in Non-small Cell Lung Cancer (NSCLC) August 15, 2024 Lung Cancer, Non-Small Cell Non-small cell lung cancer Pembrolizumab Dostarlimab Platinum-based chemotherapy doublet Programmed death ligand 1 Positron emission tomography Organoids Artificial intelligence Machine learning Pembrolizumab Dostarlimab Pemetrexed+ (carboplatin or cisplatin) 40 GSK Investigational Site London SE1 9RT United Kingdom NCT06405217 Nanjing First Hospital, Nanjing Medical University Recombinant Human Thyroid Stimulating Hormone for Radioiodine 131I Treatment April 20, 2024 DTC - Differentiated Thyroid Cancer Thyroid Stimulating; Hormone, C Radiotherapy; Complications Recombinant Human Thyroid Stimulating Hormone 30 Nanjing First Hospital Nanjing Jiangsu 210006 China NCT06405204 Beni-Suef University of Myo-inositol, Melatonin and Co-enzyme q10 on Ovarian Reserve June 30, 2024 IVF Myo-inositol Melatonin Co-enzyme q10 ovarian reserve Myoinositol Co-Enzyme Q10 Melatonin Folic acid 200 Beni-suef university Hospital Banī Suwayf 62511 Egypt NCT06405191 Inonu University The Effect of Web-based Education on Psychomotor Skills Education in Nursing March 1, 2021 Nursing Education Web based education 90 Hakime Aslan Malatya 44800 Turkey NCT06405178 Beni-Suef University Adjuvant Therapy With Letrozole in Induction of Ovulation With Polycystic Ovarian Syndrome September 30, 2024 Polycystic Ovary Sodium-Glucose Co-Transporter-2 Inhibitors Letrozole Ovulation Polycystic Ovarian Syndrome Metformin Dapagliflozin Dapagliflozin/Metformin Letrozole 500 Beni-suef university Hospital Banī Suwayf 62511 Egypt NCT06405165 Bilecik Seyh Edebali Universitesi Jigsaw Learning Model and Urinary Catheter Care May 15, 2024 The Effect of the Flipped-Jigsaw Learning Model on Learning flipped training Jigsaw learning model nursing students urinary catheter care student success 100 NCT06405152 Swedish Orphan Biovitrum Assessment of Macrophage Activation syndromE in STill's Disease September 27, 2023 Macrophage Activation Syndrome Still's Disease, Adult-Onset Stills Disease, Juvenile-Onset Chart review 80 Swedish Orphan Biovitrum Research Site Swedish Orphan Biovitrum Research Site Swedish Orphan Biovitrum Research Site Swedish Orphan Biovitrum Research Site Swedish Orphan Biovitrum Research Site Swedish Orphan Biovitrum Research Site Swedish Orphan Biovitrum Research Site Swedish Orphan Biovitrum Research Site Swedish Orphan Biovitrum Research Site Swedish Orphan Biovitrum Research Site Swedish Orphan Biovitrum Research Site Los Angeles Atlanta Cincinnati Philadelphia Calgary Paris Heidelberg Milan Rome Utrecht Barcelona California Georgia Ohio Pennsylvania 90095 30329 45229 19104 United States United States United States United States Canada France Germany Italy Italy Netherlands Spain NCT06405139 Cancer Institute and Hospital, Chinese Academy of Medical Sciences Nanoliposomal Irinotecan, Oxaliplatin Plus Capecitabine as Conversion Therapy of Locally Advanced Colorectal Cancer May 6, 2024 Colorectal Cancer Locally Advanced Colorectal Cancer Nanoliposomal Irinotecan Oxaliplatin Capecitabine Conversion Therapy Nanoliposomal Irinotecan, Oxaliplatin plus Capecitabine 36 Cancer Institute and Hospital, Chinese Academy of Medical Sciences Beijing China NCT06405126 KU Leuven Validation of a Machine Learning Predictive Model to Distinguish Post-capillary Pulmonary Hypertension February 21, 2024 Pulmonary Hypertension Pulmonary Arterial Hypertension HFpEF - Heart Failure With Preserved Ejection Fraction pulmonary hypertension pulmonary arterial hypertension post-capillary pulmonary hypertension HFpEF artificial intelligence diagnostic tool machine learning non-invasive diagnosis Optiek predictive model 100 Ziekenhuis Oost-Limburg Jessa Hospital UZ Leuven AZ Groeninge Genk Hasselt Leuven Kortrijk Limburg Limburg Vlaams Brabant West-Vlaanderen 3600 3500 3000 8500 Belgium Belgium Belgium Belgium NCT06405113 Changzhou No.2 People's Hospital FMT+SOX+Sintilimab as First-line Treatment for Advanced Gastric Cancer June 1, 2024 Gastric Cancer Fecal Microbiota Transplantation (FMT)+chemotherapy+immunotherapy 198 NCT06405100 Air Force Military Medical University, China Efficacy and Safety of Tacrolimus in Combination With Ripertamab in the Initial Treatment of Patients With MCD May 2024 Minimal Change Disease Supportive care+Prednisone Supportive care+Tacrolimus+Ripertamab Supportive care+Ripertamab 81 NCT06405087 Takeda A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD) December 2, 2024 Ulcerative Colitis Crohn's Disease Drug Therapy Vedolizumab SC No Intervention 70 NCT06405074 Washington D.C. Veterans Affairs Medical Center Low Intensity Focused Ultrasound for Tobacco Use Disorder: High Resolution Targeting of the Human Insula April 1, 2022 Tobacco Use Disorder low intensity focused ultrasound functional magnetic resonance imaging insula low intensity focused ultrasound (LIFU) 44 Veterans Affairs Medical Center Washington District of Columbia 20422 United States NCT06405061 Tianjin Medical University Cancer Institute and Hospital A Prospective, Single-arm, Multicenter Phase II Clinical Study of HAIC in Combination With Adebrelimab and Bevacizumab for Potentially Resectable Hepatocellular Carcinoma May 1, 2024 Adebrelimab Hepatocellular Carcinoma Adebrelimab 40 Peking Union Medical College Hospital Peking University Cancer Hospital & Institute Tianjin Cancer Hospital Airport Hospital Third Central Hospital of Tianjin Tianjin First Central Hospital Tianjin Medical University General Hospital Beijing Beijing Tianjin Tianjin Tianjin Tianjin Beijing Beijing Tianjin Tianjin Tianjin 300308 China China China China China China NCT06405048 Fudan University Impact of a Mock-up Fact-checking Extension on HPV Vaccine Misinformation: A Survey Experiment April 28, 2024 HPV Vaccine HPV vaccine knowledge misinformation vaccine confidence fact-checking extension Mobile Weibo post screenshot with mock-up Chinese fact-checking extension 1200 Chizhou Health Center for Disease Control and Prevention Jiading District Center for Disease Control and Prevention Chizhou Shanghai Anhui Shanghai 247100 201800 China China NCT06405035 European Institute of Oncology Dissecting the Role of MIcrobioMe in gastroEsophageal Tumor: a multIdisCiplinary Longitudinal Study March 8, 2022 Adenocarcinoma gastroesohageal adenocarcinoma neoadjuvant chemotherapy microbiome radiomics predictive factor risk factor nutrition genomics patient-centric model 140 European Institute of Oncology Milan Italy NCT06405022 Department of Public Health, Denmark Does Sport Specific Brain Endurance Training Enhance Physical and Cognitive Performance in Elite Orienteering Athletes? March 1, 2021 Healthy Elite Athletes Brain Endurance Training Control 18 Aarhus University Aarhus C 8000 Denmark NCT06405009 Northern Jiangsu People's Hospital Prediction Model of Occult Omental Metastasis in Patients With Gastric Cancer April 22, 2024 Gastric Cancer Omental Metastasis Without any intervention, we only divided gastric cancer patients into two groups based on postoperative pathology, and analyzed their basic characteristics and risk factors 450 Yifan Cheng Yangzhou Jiangsu 225000 China NCT06404996 King Abdullah International Medical Research Center Smartphone Application Versus Conventional Paper for the Documentation of Voiding Dysfunction in Children May 1, 2024 Voiding Dysfunction Children voiding dysfunction bladder children voiding diary smartphone Smartphone Voiding Diary Paper voiding diary 100 NCT06404983 University of Ioannina Opioid-free Anaesthesia in Breast Cancer Surgery December 28, 2022 Breast Cancer Anesthesia Pain, Postoperative Pain, Chronic Opioid Free Anaesthesia Cancer Recurrence Opioid Free Anaesthesia (OFA) Conventional General Anaesthesia (CGA) 200 University Hospital of Ioannina Ioannina Epirus 455 00 Greece NCT06404970 VA Office of Research and Development A Partnered Evaluation to Improve the Identification and Management of Functional Impairment and Frailty Among Older Veterans in Primary Care Settings July 1, 2024 Functional Impairment Frailty adult, aged adult, middle aged primary health care functional status frailty patient reported outcome measures Screening intervention Standard bundle of implementation strategies Enhanced bundle of implementation strategies 10000 Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA Philadelphia Pennsylvania 19104-4551 United States NCT06404957 Sakarya University Effect of Mindfulness-based Applied to Hemodialysis Patients on Psychosocial Adaptation July 1, 2022 Hemodialysis Psychosocial Adaptation Mindfulness Hemodialysis Nursing Psychosocial Adaptation Mindfulness-based Applied Active Comparator: Control groups 32 Çiğdem Şen Tepe Sakarya 54050 Turkey NCT06404944 I.M. Sechenov First Moscow State Medical University Using of Implants With a Sloped Platform Edge January 1, 2021 Bone Resorption Alveolar ridge atrophy Implant design Bone loss implantation implantation 30 I.M. Sechenov First Moscow State Medical University (Sechenov University) Moscow Russian Federation NCT06404931 Hospital Mutua de Terrassa Transvaginal Human Acellular Dermal Matrix for Prolapse Treatment May 1, 2024 Prolapse; Female Prolapse Genital Prolapse Uterovaginal Vaginal hysterectomy plus matrix reinforcement and sacrospinous fixation with Anchorsure® device Vaginal hysterectomy plus anterior colporrhaphy Vaginal hysterectomy plus sacrospinous fixation with Anchorsure® device 90 NCT06404918 Benha University Preemptive Erector Spinae Plane Block Versus Serratus Anterior Plane Block in MRM January 22, 2023 Modified Radical Mastectomy Erector Spinae Plane Block Serratus Anterior Plane Block Erector spinae plane group Serratus anterior plane group 70 Benha University Banha 13511 Egypt NCT06404905 Cancer Institute and Hospital, Chinese Academy of Medical Sciences Clinical Trial of BT02 in Patients With Advanced Solid Tumors January 24, 2024 Advanced Solid Tumor Advanced Solid Tumors BT02 monoclonal antibody injection 60 Cancer Institute and Hospital Beijing Biejing 1000021 China NCT06404892 Hospital Nossa Senhora da Conceicao ARISCAT, ASA and LAS VEGAS Risk Scores and the Incidence of Postoperative Pulmonary Complications in Thoracic Surgery July 1, 2024 Postoperative Complications postoperative pumonary complications ARISCAT score LAS VEGAS score ASA score Single-lung ventilation 110 NCT06404879 Giresun University The Effect of Parental Anxiety Level on the Child's Anxiety Level and Postoperative Pain in Children Undergoing Surgery. May 30, 2024 Anxiety Children children anxiety analgesia pediatric anaesthesia determining scores with tests 90 Giresun Gynecology and Pediatrics Training Research Hospital Giresun Centre 28000 Turkey NCT06404866 Indiana University Satisfaction With eMotion in a Diverse Group of Women May 1, 2024 Cardiac Events Emotions Emotion Regulation eMotion 30 NCT06404853 Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria Effect and Safety of the Dietary Supplement Mannite in Pediatric Patients With Chronic Functional Constipation March 16, 2021 Constipation - Functional constipation Manna 110 SC Pediatria Alessandria Piedmont 15121 Italy NCT06404840 Tianjin Medical University Cancer Institute and Hospital Evaluating Nimotuzumab in Combination With AG Regimen for Pancreatic Cancer With Liver Metastases : A Prospective, Single-Arm, Phase II Study May 6, 2022 Pancreatic Cancer nimotuzumab AG chemotherapy 30 Tianjin Cancer Hospital Airport Hospital Tianjin Tianjin 300308 China NCT06404827 Hasan Kalyoncu University The Effect of Hippotherapy Simulator in Children With Spastic Cerebral Palsy May 2024 Cerebral Palsy Cerebral Palsy Horseback riding simulator Selective motor control Balance Horseback riding simulator Routine Physiotherapy and Rehabilitation 26 Gaziantep Gaziantep 27100 Turkey NCT06404814 Superior University Effectiveness of Functional Electrical Stimulation Versus Spencer Technique in Patients With Adhesive Capsulitis September 1, 2023 Adhesive Capsulitis Transcutaneous electrical nerve stimulation (TENS) Muscle Energy Technique 32 Johar pain relief center Lahore Punjab Pakistan NCT06404801 Superior University Development of Stance Control Orthotic Knee Joint For Improvement of KAFO Users November 1, 2023 Ankle Osteoarthritis Knee Stance Control 2 Peshawar North West General Hospital & Research Center Peshawar Khyber Pakhtunkhwa Pakistan NCT06404788 Medical University of Silesia Anxiety Level Among Patients With Chronic Low Back Pain May 6, 2024 Anxiety Disorders Anxiety Disorders and Symptoms Lower Back Pain Chronic Pain chronic pain low back pain anxiety 300 NCT06404775 Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University External Mastalgia-oil Versus Oral Tamoxifen in Premenopausal Women With Severe Mastalgia May 16, 2024 Mastalgia mastalgia-oil, tamoxifen placebo mastalgia-oil placebo, tamoxifen 456 Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Guangzhou Guangdong 510120 China NCT06404762 Gazi University Tuberosity Versus Palatal Connective Tissue Graft on the Treatment of Single Maxillary Recession-type Defects July 1, 2023 Gingival Recession, Localized Maxillary Tuberosity Connective Tissue Graft Coronally Advanced Flap tSCTG+ CAF pSCTG+ CAF 30 Gazi University Faculty of Dentistry Ankara Çankaya 06490 Turkey NCT06404749 Future Biome SA Fungal Fiber for Gut Health May 3, 2024 Mild Gastrointestinal Symptoms in Healthy Adults Low-grade Chronic Inflammation Stress Gut Health Gut Permeability Gut Microbiome Immune Response Activity of Daily Living Nutrition, Healthy gut microbiome gut health healthy women perimenopause pre menopause middle aged women fiber gut brain axis low grade chronic inflammation prebiotic fungal fiber inulin 20 Consultorios Del Dr Jorge Eduardo Tartaglione Ciudad Autonoma de Buenos Aires Caba 1123 Argentina NCT06404736 Fudan University QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk TNBC Breast Cancer May 7, 2024 Early Breast Cancer Neoadjuvant Therapy TNBC, Triple Negative Breast Cancer TNBC, Triple Negative Breast Cancer Early breast cancer Neoadjuvant Therapy Bispecific antibody (bsAb) targeting PD-1 and CLTA-4 Albumin-bound paclitaxel Carboplatin 73 Zhimin Shao Shanghai Not US/Canada 200032 China NCT06404723 Sohag University The Predictive and Prognostic Values of the Fibrinogen to Albumin Ratio and C-reactive Protien to Albumin Ratio in Systemic Lupus Erythematosus Patients June 1, 2024 Systemic Lupus Erythematosus Fibrinogen to albumin Ratio and C-reactive to Albumin Ratio 150 NCT06404710 Saglik Bilimleri Universitesi Progressive Muscle Relaxation Exercise Applied After Heart Surgery October 18, 2023 the Participant Wishes to Leave the Study progressive muscle relaxation anxiety quality of recovery heart surgery sleep pain Exercise 57 Özel Bilgi Hastanesi Ankara 06510 Turkey NCT06404697 Ruijin Hospital Boost Irradiation to the Supraclavicular Area Among High Risk cN3c Breast Cancer Patients May 2024 Breast Cancer cN3c Boost irradiation breast cancer high risk Boost irradiation 24 Ruijin hospital, Shanghai jiaotong university school of medicine Shanghai Shanghai China NCT06404684 Region Stockholm Psychological Treatment for Paraphilic Disorders October 2024 Paraphilic Disorders paraphilic disorders Cognitive behavioral therapy (CBT) 14 Josephine Savard Stockholm 171 76 Sweden NCT06404671 Alexandria University Timing of Surgery After Neoadjuvant Chemotherapy for Advanced Ovarian Cancer September 15, 2023 Ovarian Epithelial Cancer high grade serous advanced primary ovarian cancer interval cytoreduction Delayed interval cytoreductive surgery (DICS) Early interval cytoreductive surgery (EICS) 250 Elshatby Maternity University Hospital Alexandria Egypt NCT06404658 Beni-Suef University Analgesic Efficacy of Genicular Nerve Block Versus (IPack Block ) in Patients Undergoing (ACL) Repair May 12, 2024 Post Operative Pain Genicular nerve block 120 Benisuef University Hospital Benisuef Egypt NCT06404645 RenJi Hospital A Clinical Prospective Observational Study of Near Infrared Spectroscopy to Detect Subcranial Hematoma May 1, 2024 Intracranial Hemorrhages Near-infrared spectroscopy detection 20 Brain Injury Center, Renji Hospital, School of Medicine, Shanghai Jiao Tong University Shanghai Shanghai 201114 China NCT06404632 Region Stockholm A Group Intervention for Promoting Health-related Habits (LEV-G) April 12, 2024 Life Style Health-Related Behavior Disabilities Mental Disability Physical Acceptability of Health Care Lev-g 30 Region Stockholm Stockholm Stockholm, Sweden 104 31 Sweden NCT06404619 Princess Nourah Bint Abdulrahman University Impact of mHealth Implementation Program on Improving Nursing Students' Lifestyle August 1, 2023 Healthy Lifestyle lifestyle mHealth nursing student Education program 220 College of Nursing Princess Nourah bint Abdulrahman University Riyadh Saudi Arabia NCT06404606 Pakistan Society for Rehabilitation of Differently Abled Hospital Effect of Black Cumin and Turmeric Along With Quantum Acoustic Waveson Inflammatory Markers and Pain in Osteoarthritis. June 15, 2024 Osteoarthritis Osteoarthritis Quantum Acoustic Waves Black Cumin &Turmeric. Black cumin and turmeric with Quantum Acoustic Waves (QAW) 30 Innovative Health Concepts & Research Center Lahore Punjab 54700 Pakistan NCT06404593 Peking University Cancer Hospital & Institute Dynamic ctDNA Detection for Colorectal Cancer Liver Metastases June 18, 2019 Liver Metastases Colorectal Cancer Surgery Circulating Tumor DNA Minimal Residual Disease Minimal Residual Disease Colorectal Liver Metastases Blood sampling 270 Beijing Cancer Hospital Beijing Beijing 100000 China NCT06404580 Northern Jiangsu People's Hospital The Benefits of R Anastomotic Technique for Billroth-II Reconstruction With Braun Anastomosis During Totally Laparoscopic Distal Gastrectomy: a Propensity Score Matching Analysis March 1, 2019 the Incidences of Clavien-Dindo Grade II or Higher Anastomotic Time R anastomosis 246 Northern Jiangsu People's Hospital Yangzhou Jiangsu 225001 China NCT06404567 [Redacted] [Trial of device that is not approved or cleared by the U.S. FDA] NCT06404554 Northern Jiangsu People's Hospital A Prediction Model of Anastomotic Stricture After Rectal Cancer January 1, 2024 Colorectal Cancer Rectal Cancer Anastomotic Stenosis nomogram rectal cancer anastomotic stricture without any intervention 1542 Yifan Cheng Yangzhou Jiangsu 225000 China NCT06404541 Kasr El Aini Hospital A Comparative Study Between Preservative With Benzalkonium Chloride vs Preservative Free Eye Drops on the Ocular Surface January 10, 2024 Ocular Surface Disease Dry Eye Syndromes Dexamethasone, tobramycin, netilimicin 60 KasrAl Ainy Hospital Cairo Giza 11956 Egypt NCT06404528 Wuxi People's Hospital Low-dose Chemotherapy Under Hypoglycaemia for the Treatment of Relapsed Refractory Advanced Solid Tumours September 4, 2023 Solid Tumors, Adult Blood glucose stress combined with low-dose chemotherapy 300 Wuxi People's Hospital Wuxi Jiangsu 214043 China NCT06404515 Weill Medical College of Cornell University Telehealth Group Counseling and Preventive Care for Women May 24, 2024 ASCVD NSTEMI STEMI Coronary Artery Disease Acute Coronary Syndrome Myocardial Infarction Unstable Angina Chest Pain ASCVD NSTEMI STEMI Coronary Artery Disease ACS Myocardial Infarction Unstable Angina Chest Pain Telehealth Group Counseling 50 Weill Cornell Medicine New York New York 10022 United States NCT06404502 University of Zurich Feasibility and Acceptability of PRISMA for Prisoners in Switzerland December 8, 2023 Psychological Distress Anxiety Depression Suicidal Ideation PRISMA 40 University of Zurich Zürich Zurich Switzerland NCT06404489 Università Vita-Salute San Raffaele Prehabilitation in Oncological Patients Undergoing Major Gastrointestinal Surgery (PROGRESS) May 2024 Oncological Patients Major Surgery Prehabilitation Multimodal prehabilitation program Standard care treatment Major gastrointestinal surgery Hospital stay Functional walking Nutrition Diet Exercise Relaxation Oncology Functional recovery Anesthesiology Multimodal prehabilitation Program 400 Azienda Ospedaliera Universitaria IRCCS San Raffaele Scientific Institute Cagliari Milan Sardegna 20132 Italy Italy NCT06404476 Izmir Katip Celebi University Evaluation of Salivary Galectin-8, Galectin-9 and RANKL Levels of Individuals With Different Periodontal Diseases May 3, 2024 Periodontal Diseases saliva obtaining 60 Izmir Katip Çelebi University İzmir Çiğli 35640 Turkey NCT06404463 Fudan University QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk ER+/HER2- Breast Cancer May 6, 2024 Early Breast Cancer Neoadjuvant Therapy HR+HER2- Breast Cancer QL1706 (bispecific antibody targeting PD-1 and CLTA-4) Albumin-bound paclitaxel Doxorubicin Cyclophosphamide Epirubicin 76 NCT06404450 University of California, San Francisco Transforming Health and Reducing Perinatal Anxiety Through Virtual Engagement May 15, 2024 Anxiety Digital CBT 132 University of California, San Francisco San Francisco California 94118 United States NCT06404437 Friedrich-Alexander-Universität Erlangen-Nürnberg Detection of Aortic Stenosis With Smartphone Auscultation Using Machine Learning (HEARTBEAT-Pilot) March 9, 2023 Aortic Valve Stenosis Machine Learning Digital Health Heart Valve Disease Cardiology Auscultation 100 Deparment of Medicine 2 - Cardiology and Angiology, Friedrich-Alexander-Universität Erlangen-Nürnberg Erlangen 91054 Germany NCT06404424 Efferon JSC Combined Hemoperfusion and Therapeutic Plasma Exchange for Treatment of Patients With Septic Shock May 1, 2022 Sepsis Septic Shock Sepsis Septic shock lipopolysaccharide sorption cytokines apsorbtion extracorporeal therapy Efferon LPS Efferon CT 82 City clinical hospital named after S. S. Yudin, Moscow City Health Department Moscow Russian Federation NCT06404411 Chengdu Sport University The Efficacy of Aerobic Exercise in the Rehabilitation of Patients With COVID-19-Related Myocardial Injury June 30, 2024 Long COVID Myocardial Injury Assigned interventions conventional rehabilitation 40 NCT06404398 Tanta University Clinical Evaluation of Single Versus Multi-Shade Direct Composite Resin Veneers July 19, 2022 Tooth Discoloration OMNICHROMA Single shade Veneers USPHS criteria Clinical OMNICHROMA, Ceram. x spectra 20 Restorative Department, Faculty of Dentistry, Tanta University Tanta 31527 Egypt NCT06404385 University of Valencia Accuracy of Static Computer-assisted Implant Surgery in Distal Free-end Scenarios September 11, 2012 Dental Implant Computer-assisted accuracy computer-assisted surgery computer-aided design analogic dental implants Static computer-assisted guided surgery with analogic guide Static computer-assisted guided surgery with CAD-CAM surgical guide 27 University of Valencia. Faculty of Medecine and Dentistry. CLINICA ODONTOLOGICA Valencia 46010 Spain NCT06404372 Sutura Medical Technology LLC A Pivotal, Blinded Multi-Center Study to Show the Safety and Effectiveness of the Demetech Barbed PDO Suture April 21, 2022 Wrinkle Suture Sutura Demetech Barbed PDO Suture Novathreads Demetech Barbed PDO Suture 57 Rejuva Medical Aesthetics Cosmetic Injectables Center Vedas Med Spa Dr. Kristin Tarbet Facial Plastic Surgery Los Angeles Sherman Oaks The Woodlands Bellevue California California Texas Washington 90025 91423 77381 98004 United States United States United States United States NCT06404359 University of Salamanca Effects of a Strength Physical Exercise Program in Colorectal Cancer Patients Undergoing Chemotherapy Treatment June 1, 2024 Oncology Chemotherapy-induced Peripheral Neuropathy Exercise Physiotherapy Exercise Physical activity recommendations 40 NCT06404346 Superior University Comparative Effectiveness of HVT and Bowen Technique in Patients of SI Joint Dysfunction With Upslipped Innominates October 1, 2023 Joint Diseases High Velocity Thrust Bowen therapy 26 Govt. Hospital Kot Kahwaja Saeed Lahore Punjab Pakistan NCT06404333 University of Oxford Evaluating Pediatric Ivermectin in Children Under 15 kg (EPIC-15) October 1, 2024 Scabies ivermectin pediatric CHILD-IVITAB CHILD-IVITAB CHILD-IVITAB 66 Fundação de Dermatologia Tropical e Venereologia Alfredo da Matta (FUAM) Manaus 69065-130 Brazil NCT06404320 Unity Health Toronto Physical Activity Program for TRD May 2024 Treatment-resistant Depression Major Depressive Disorder Major Depressive Disorder Physical Activity Exercise PA program - MoveU.HappyU 30 St. Michael's Hospital, Unity Health Toronto Toronto Ontario Canada NCT06404307 Erasmus Medical Center Self-administration in Outpatient Parenteral Antimicrobial Therapy Service May 2024 Infections Bacterial Infections Outpatient Antimicrobials Outpatient Parenteral Antimicrobial Treatment Self-administration 100 Amphia hospital Erasmus MC Breda Rotterdam Noord-Brabant Zuid-Holland 4818CK 3000WB Netherlands Netherlands NCT06404294 Children's Hospital of Chongqing Medical University The External Diaphragm Pacemaker Assisted Extubation in Premature Infants With Invasive Mechanical Ventilation March 31, 2024 Invasive Mechanical Ventilation Extubation External Diaphragm Pacemaker Invasive Mechanical Ventilation Extubation Preterm Infants External Diaphragm Pacemaker treatment 40 Children's hospital of Chongqing Medical University Chongqing Chongqing 400014 China NCT06404281 Changzhou No.2 People's Hospital γδ T-PD-1 Ab Cells in the Treatment of Advanced Solid Tumors June 1, 2024 Advanced Solid Tumor γδ T-PD-1 Ab cells 9 NCT06404268 University of Maryland, Baltimore Facilitating Neuroplastic Changes of Acute Stroke Survivors May 2024 Stroke Stroke Paraplegia Acute Motor relearning training Passive stretching Gamed-based active movement training Passive movement Active movement training Ankle torque and motion measurement 100 NCT06404255 Université Paris-Saclay Impact of a Stress Management Training Course May 15, 2024 Stress Stress management training 300 NCT06404242 University Medical Center Ho Chi Minh City (UMC) Plaque Characteristics Predict Recurrent Stroke in MCA Stroke Patients April 1, 2024 Stroke, Ischemic Atherosclerosis, Cerebral 125 University Medical Center Ho Chi Minh City Ho Chi Minh City 70000 Vietnam NCT06404229 University of Manchester Use of CPETarm for Risk Stratification of Patients With CLTI May 28, 2024 Chronic Limb-Threatening Ischemia Surgery-Complications CardioPulmonary Exercise Testing Risk Stratification CardioPulmonary Exercise Testing 120 University of Manchester Manchester Greater Manchester M13 9PL United Kingdom NCT06404216 University of Haifa Nordic Walking Training Program for Sustaining Independent Walking in Older Adult Evacuees May 16, 2024 Aging Mental Health Issue War-Related Trauma Nordic walking group training 31 NCT06404203 Medipol University The Effect of Oral Use of Lyophilised Royal Jelly on Cognitive Functions and Immune System in Elderly Individuals July 1, 2024 Cognitive Change Balparmak Apitera Royal Jelly Herbal Capsule Food Supplement 500 mg/day Balparmak Apitera Royal Jelly Herbal Capsule Food Supplement 1000 mg/day Balparmak Apitera Royal Jelly Herbal Capsule Food Supplement 1500 mg/day Plasebo 120 NCT06404190 Krishnadevaraya College of Dental Sciences & Hospital Diode Laser Photo Activation for Pocket Reduction Decontamination A Clinical Study May 28, 2023 Pocket, Periodontal Periodontal Inflammation Periodontal Attachment Loss Periodontitis Diode laser and 3% hydrogen peroxide 10 Anusha s Bengaluru Karnataka 562157 India NCT06404177 Hôpital Universitaire Sahloul Enantyum® IV Versus Piroxen® IM in Emergency Pain Management July 15, 2023 Traumatic Injury Dexketoprofen Piroxicam 300 Sahloul University Hospital Sousse 5000 Tunisia NCT06404164 Guangdong Provincial People's Hospital Pulmonary Watershed Topographic Map Navigation for Lung Nodule Resection January 30, 2022 Pulmonary Function Assessment Disease Free Survival NSCLC, Stage I Watershed Analysis wedge resection Wedge resection under watershed analysis method 3000 Guangdong Provincial People's Hospital Guangzhou Guangdong China NCT06404151 Dr. Lutfi Kirdar Kartal Training and Research Hospital Comparison of Oxygen Reserve Index and Regional Cerebral Oxygen Saturation Indetermining Hypoxia in Obese Patients July 1, 2023 Oxygen Deficiency Oxygen reserve index, Preoxygenation Cerebral Oxygen Saturation monitoring 70 University of Health Science, Kartal Dr Lütfi Kırdar Training and Research Hospital Istanbul Turkey NCT06404138 Universitaire Ziekenhuizen KU Leuven Recovery From Disability After Geriatric-home Rehabilitation Versus Standard of Care: Pilot Study May 1, 2024 Disability Physical Disability Geriatric Rehabilitation The Geriatric Activation Program (GAPP) Home version Standard of care 24 CHU UCL Namur UZ Leuven Godinne Leuven 5530 3000 Belgium Belgium NCT06404125 Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey Investigation of the Effect of Central Sensitization Symptom Severity on Steroid Injection Results in Shoulder Pain March 1, 2023 Rotator Cuff Lesion Subacromial Impingement Syndrome Shoulder Pain Chronic Pain central sensitization chronic pain Subacromial Shoulder Pressure Range of Motion of Shoulde Joint Hand Grip Test Numeric Rating Scale Pain-Pressure Threshold Measurement With an Algometer Quick DASH SF-36 Central Sensitization Scale Hospital Anxiety and Depression Scale 36 Sultan 2. Abdulhamid Han Training and Research Hospital İstanbul Üsküdar 34674 Turkey NCT06404112 Duke University RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD) July 2024 Long COVID Long COVID-19 Sleep Disturbance PASC Sleep Disturbances Melatonin Melantonin Placebo Tailored lighting (TL) Active Tailored lighting (TL) Placebo 600 NCT06404099 Duke University RECOVER-SLEEP: Platform Protocol, Appendix_A (Hypersomnia) July 2024 Long COVID Long COVID-19 Hypersomnia PASC Modafinil Modafinil Placebo Solriamfetol Solriamfetol Placebo 474 NCT06404086 Duke University RECOVER-SLEEP: Platform Protocol July 2024 Long COVID Long COVID-19 Hypersomnia Sleep Disturbance PASC Modafinil Modafinil Placebo Solriamfetol Solriamfetol Placebo Melatonin Melantonin Placebo Tailored lighting (TL) Active Tailored lighting (TL) Placebo 1074 NCT06404073 Duke University RECOVER-ENERGIZE Platform Protocol_Appendix B (Structured Pacing (PEM)) June 2024 Long COVID Long Covid19 Long Covid-19 PASC Exercise PEM (post exertional malaise) Structured Pacing Usual Care 300 NCT06404060 Duke University RECOVER-ENERGIZE Platform Protocol_Appendix A (Exercise Intolerance) June 2024 Long COVID Long Covid19 Long Covid-19 PASC Exercise PEM (post exertional malaise) Personalized Cardiopulmonary Rehabilitation Education 360 NCT06404047 Duke University RECOVER-ENERGIZE Platform Protocol June 2024 Long COVID Long Covid19 Long Covid-19 PASC Exercise PEM (post exertional malaise) Personalized Cardiopulmonary Rehabilitation Structured Pacing Education Usual Care 660 NCT06404034 xCures Expanded Access to Gallium Maltolate (GaM) Glioblastoma Refractory Glioblastoma Glioblastoma Multiforme glioblastoma refractory glioblastoma Gallium Maltolate NCT06404021 University of Calabria Electronic Device Implantation Through Remote Guidance June 1, 2022 Telemedicine Heart Failure Defibrillators electrophysiology remote monitoring technical support device interventional cardiology procedures with proctoring system interventional cardiology procedures with engineer in the electrophysiology laboratory 50 "Magna Graecia" University of Catanzaro Catanzaro 88100 Italy NCT06404008 University of Texas at Austin A Controlled Breathing Intervention to Reduce Stress and Improve Symptoms in COPD Patients (REST) May 2024 COPD Stress Dyspnea REST Education 36 NCT06403995 Université de Sherbrooke Evidence-based Internet Cognitive-behavioral Therapy for Social Anxiety August 2024 Social Anxiety Anxiety Social anxiety Internet Cognitive behavioural therapy Community-based primary health care Quasi-experimental design Canada Internet-based cognitive behavioral therapy for social anxiety 252 NCT06403982 Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland The Influence of Oxytocin on Intrapartum Fetal Well-being and Delivery Outcomes in Patients Receiving Epidural Analgesia May 6, 2024 Uterine Contraction Oxytocin Labor Progress Fetal Doppler Labor Epidural Analgesia Labor Pain epidural anaesthesia use of oxytocin uterine contractions fetal well-being fetal doppler ctg fetal monitoring labor analgesia labor pain labor progression 200 NCT06403969 Värmland County Council, Sweden Sleep in Children With Autism and Intellectual Disability May 14, 2024 Insomnia Autism Intellectual Disability applied behavior analysis polysomnography insomnia autism Applied Behavior Analysis 15 NCT06403956 Çankırı Karatekin University Students' Hand Hygiene Beliefs, Practices and Skills January 15, 2024 Complications of Medical and Surgical Care (Y62-Y84) Education Hand hygiene Home care services Skills Training with video Training with paint 75 Çankırı Karatekin University Ankara 06100 Turkey NCT06403943 Beijing Chest Hospital Efficacy Safety BaiDiZiYin ShenQiYiFei Adjunctive Treatments Pulmonary Tuberculosis May 29, 2023 Adjuvant Treatment Tuberculosis BaiDiZiYin Pill, ShenQiYiFei Pill Anti tuberculosis chemotherapy 292 Beijing Chest Hospital affiliated to Capital Medical University Beijing Beijing 101149 China NCT06403930 Badr University Accuracy of Maxillary Obturator Bulb in Maxillectomy Defects May 15, 2024 Maxillary Obturators Maxillary Obturator 19 Faculty of oral and dental medicine Cairo 31645 Egypt NCT06403917 Assiut University Evaluation of Breast Cancer Screening Program at Assiut Governorate June 1, 2024 Breast Cancer Evaluation of breast screening 15000000 NCT06403904 Azienda Ospedaliero-Universitaria di Modena Assessing Clinical Features and Outcome of Breast Cancer in PALB2 Mutation Carriers: the Palbreast Study October 2, 2023 Breast Cancer 600 Aou Modena Modena 41125 Italy NCT06403891 Ankara City Hospital Bilkent The Effect of a Comprehensive Rehabilitation Program Using Robotic Walking and Functional Electrical Stimulation Technologies on Balance and Walking in Children With Cerebral Palsy March 15, 2022 Cerebral Palsy 30 Ankara Bilkent City Hospital Ankara 06800 Turkey NCT06403878 Sichuan University Safety and Efficacy of Neoadjuvant Immunochemotherapy in Elderly Patients With Resectable Esophageal Cancer May 2024 Esophageal Cancer Carboplatin Nab paclitaxel Sintilimab 68 West-China Hospital Chengdu China NCT06403865 University Paris 7 - Denis Diderot Patient-Reported Outcomes in Real-life of Cabotegravir and Rilpivirine May 2024 Quality of Life Long-Acting Injectable Regimen HIV Patient-reported Outcomes Treatment switch Cabotegravir, Rilpivirine Drug Combination 280 NCT06403852 University of Michigan Investigating Near-Threshold Perception During Anesthetic Sedation May 6, 2024 Propofol Anesthesia fMRI Hypnotics and Sedatives Central Nervous System Depressants Physiological Effects of Drugs Anesthetics, Intravenous Anesthetics, General Anesthetics Propofol Functional Magnetic Resonance Imaging (fMRI) with propofol 28 University of Michigan Ann Arbor Michigan 48109 United States NCT06403839 Odense University Hospital Impact of Preoperative Dental Screening in Reducing Infective Endocarditis Risk in Surgical Valve Replacement Patients January 1, 2020 Surgical Valve Replacement Dental Endocarditis No preoperative dental screening 1000 Odense University Hospital, Cardiac Surgery Department Odense 5000 Denmark NCT06403826 University Hospital, Basel, Switzerland SHIFT Hospital in Motion (Pilot Study) January 10, 2023 Hospitalized Patients Physical Inactivity Movement detection Activity sensors Sensor positioning Algorithm development 40 Universitiy Hospital Basel, Division of Internal Medicine Basel Basel-Stadt 4031 Switzerland NCT06403813 NYU Langone Health Adolescent Digital Mental Health-Kenya Effectiveness April 22, 2024 Mental Disorder in Adolescence mHealth Toolkit for Screening & Empowering Lives of Youth (mSELY-A) for Adolescents mHealth Toolkit for Screening & Empowering Lives of Youth (mSELY-P) for Parents Control Tooklit 600 University of Nairobi Nairobi Kenya NCT06403800 National Heart and Lung Institute Silicosis and Silicotuberculosis Among Small Scale Gemstone Miners in Northern Tanzania March 11, 2024 Silicosis Tuberculosis Silicosis; With Tuberculosis Occupational Lung Diseases Epidemiology Respiratory Infection Tuberculosis Silicosis No intervention 1400 Kibong'oto Infectious Diseases Hospital Sanya Juu Kilimanjaro PO Box Tanzania NCT06403787 University of Guadalajara Effect of Aerobic Training and Ginkgo Biloba on Lipids Levels in HIV-positive Patients Undergoing Antiretroviral Treatment May 1, 2022 Human Immunodeficiency Virus HIV-positive individuals Aerobic exercise training Ginkgo biloba extract Plasma lipid concentrations Aerobic exercise + Ginkgo Biloba Extract Aerobic exercise + Calcined magnesia (placebo) Aerobic exercise + Atorvastatin 28 University Center for Health Sciences Guadalajara Jalisco 44340 Mexico NCT06403774 Saglik Bilimleri Universitesi Bowel Preparation Before Hemorrhoidectomy July 1, 2023 HEMORRHOIDECTOMY HEMORRHOIDECTOMY BOWEL PREPARATION PAIN COMFORT Group that will undergo bowel preparation using laxatives (Two bowel X-M Solution 250 ml.) Group that will undergo bowel preparation using enema (Two bowel E.S. Enema ) 60 Sağlık Bilimleri Üniversitesi Ankara 06280 Turkey NCT06403761 Novo Nordisk A/S Investigating How CagriSema, Semaglutide and Cagrilintide Regulate Insulin Effects in the Body of People With Type 2 Diabetes May 6, 2024 Diabetes Mellitus, Type 2 Semaglutide Cagrilintide Placebo semaglutide Placebo cagrilintide 150 Profil Institut für Stoffwechselforschung GmbH Neuss 41460 Germany NCT06403748 University of Bologna Effect of a Dietary Supplement on Lipid Pattern, Indexes of NAFLD and Systemic Inflammation in Healthy Subjects With Suboptimal LDL-C Levels May 6, 2024 Hypercholesterolemia Inflammation Dietary supplement formulated with components of natural origin: artichoke, danshen, bergamot, folic acid, chromium and excipients. Placebo 90 University of Bologna Bologna BO 40138 Italy NCT06403735 Qilu Pharmaceutical Co., Ltd. A Phase I Clinical Study of QLC1101 in Patients With Advanced Solid Tumors April 25, 2024 Non-small Cell Lung Cancer Colorectal Cancer Pancreatic Cancer Solid Tumor QLC1101 250 The First Affiliated Hospital of Guangdong Pharmaceutical University Harbin Medical university cancer hospital Jiangxi Cancer Hospital Shanghai east hospital Yunnan Cancer Hospital Guangzhou Ha'erbin Nanchang Shanghai Kunming Guangdong Heilongjiang Jiangxi Shanghai Yunnan 510699 150081 330029 200000 650118 China China China China China NCT06403722 Saint Thomas Hospital, Panama Perinatal Outcomes in Patients With Elevated sFlt-1/PlGF Ratio November 15, 2023 Hypertension in Pregnancy Hypertension, pregnancy induced Angiogenic factors Standard of care 190 Saint Thomas H Panama Panama NCT06403709 Cancer Institute and Hospital, Chinese Academy of Medical Sciences Irinotecan, TAS-102 Plus Bevacizumab as a Third-Line or Beyond Therapy in mCRC Patients August 1, 2022 Metastatic Colorectal Cancer Irinotecan, Trifluridine/tipiracil (TAS-102) plus Bevacizumab 35 Beijing Chaoyang Sanhuan Cancer Hospital Beijing China NCT06403696 Çanakkale Onsekiz Mart University Predicting Post-op Airway Complications in Pediatric Patients Using Ultrasonography May 2, 2024 Airway Complication of Anesthesia Airway Management Ultrasonography Pediatric Anesthesia 60 Canakkale Onsekiz Mart University Çanakkale Canakkale 17020 Turkey NCT06403683 Cairo University Physical Activity Level and Insomnia January 30, 2024 Primary Dysmenorrhea Physical Activity Level Insomnia WaLIDD score / Insomnia Severity Index (ISI) / International Physical Activity Questionnaire (Short-form) / Six-Minute Walk Test 150 Cairo University Giza Egypt NCT06403670 Baskent University Ankara Hospital Dexmedetomidine and Remifentanil in NORA December 17, 2022 Comparison of the Effects of Remifentanil and Dexmedetomidine Dexmedetomidine Remifentanil 76 Baskent University Ankara Hospital Ankara Cankaya 06490 Turkey NCT06403657 Vietnam Viral Hepatitis Alliance DEcentralize Testing, Education, and Linkage to Care by Using Electronic Best Practice Advisory for Hepatitis B (DETECT-B) May 2024 Viral Hepatitis B An enhanced model of hepatitis B testing and linkage to care 30 NCT06403644 United States Air Force Research Laboratory Evaluating the Technology and Assessing the Biological Effects of Commercially Available PhotoBioModulation Devices March 11, 2024 Physiological Wellness Photobiomodulation Recovery Wellness NovoTHOR XL Photobiomodulation Full Body Light Bed ARRC LED Photobiomodulation Full Body Light Bed 150 Wright Patterson Air Force Base Beavercreek Ohio 45324 United States NCT06403631 University of Milan Supporting Mental Health in Daily Life After the Diagnosis of Multiple Sclerosis November 6, 2023 Multiple Sclerosis observational 123 University of Bari University of Cagliari University of Catania Azienda Ospedaliera Sant'Anna University of Florence Università Vita-Salute San Raffaele San Luigi Gonzaga Hospital Azienda Ospedaliera San Camillo Forlanini Bari Cagliari Catania Como Florence Milano Orbassano Roma Italy Italy Italy Italy Italy Italy Italy Italy NCT06403618 European Institute of Oncology Evaluation of the PreCursor-M+® in CIN2 May 15, 2024 Cervical Intraepithelial Neoplasia Grade 2 100 European Institute of Oncology Milan Italy NCT06403605 ETS Wound Care, LLC Bioresorbable Glass Fiber Matrix in the Treatment of Diabetic Foot Ulcers August 29, 2022 Diabetic Foot Ulcer Ulcer Foot Diabetic Foot DFU Ulcer Mirragen Wound Matrix Fibracol 100 LA Foot and Ankle Casa Colina Center for Clincal Research Southernmost Foot and Ankle Specialists Doctor's Research Network Gateway Clinical Trials Foot and Ankle Center of Illinois Mercy Medical Center Foot and Ankle Specialists of the Mid Atlantic Wound Care Experts Lower Extremity Institute for Research and Therapy Wound Centrics PULSE: Amputation Prevention Center, LLC Foot and Ankle Specialists of the Mid Atlantic United Wound Healing P.S Los Angeles Pomona San Francisco Homestead South Miami O'Fallon Springfield Cedar Rapids Frederick Las Vegas Youngstown Corpus Christi El Paso Salem Auburn California California California Florida Florida Illinois Illinois Iowa Maryland Nevada Ohio Texas Texas Virginia Washington 90010 91769 94115 33030 33143 62269 62704 52403 21703 89148 44512 78404 79902 24153 98092 United States United States United States United States United States United States United States United States United States United States United States United States United States United States United States NCT06403592 Erasmus Medical Center The Effect of a Laryngeal Mask Airway on Optic Nerve Sheath Diameter March 25, 2024 Intracranial Pressure Increase Laryngeal airway mask Optic Nerve sheath Diameter Intracranial Pressure optic nerve sheath diamater 230 Erasmus Medisch Centrum Rotterdam Netherlands NCT06403579 Cukurova University THE EFFECT OF VIRTUAL REALITY APPLICATION ON PAIN, ANXIETY, AND COMFORT DURING CURETTAGE/DILATATION May 1, 2024 Bleeding;Post D&C PAIN, ANXIETY, AND COMFORT virtula reality goggles 80 Seda Karaçay Yıkar Adana Sarıcam 00130 Turkey NCT06403566 Cukurova University THE EFFECT OF HAND AND BACK MASSAGE ON PAIN, SLEEP AND SELF-CARE IN WOMEN UNDERGOING HYSTERECTOMY June 1, 2024 Sleep Pain Self Efficacy hand massage 102 Seda Karaçay Yıkar Adana Sarıcam 00130 Turkey NCT06403553 Chinese Medical Association FC Change From Day 1 to Day 3 Associated With SALD January 1, 2023 Liver Dysfunction Sepsis-associated Liver Dysfunction Fecal Calprotectin 96 Drum Tower Hospital Nanjing Jiangsu 210008 China NCT06403540 Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization The Impact of Laparotomy and Analgesia Methods on Diaphragm January 30, 2024 Colorectal Neoplasms Gastrectomy ultrasonography 90 Prof. Dr. Cemil Taşcıoğlu City Hospital Istanbul Turkey NCT06403527 Cardioangiologisches Centrum Bethanien Ultrasound Guyded Venous Puncture for Safe AF Ablation Procedures March 3, 2024 Puncture for Safe Atrial Fibrillation Ablation Ultrasound guided venous access during AF ablation 1836 Boris Schmidt Frankfurt Hessen 60431 Germany NCT06403514 Nova Southeastern University The Effects of a Psychoeducational Intervention on Health and Performance-based Outcomes of Veterans Diagnosed With PTSD May 2024 Post Traumatic Stress Disorder Veterans Psychological Skills Training (PST) 4 Nova Southeastern University Davie Florida 33328 United States NCT06403501 Zhejiang Sunshine Mandi Pharmaceutical Co.,Ltd. Efficacy and Safety of Clascoterone Cream 1% in Facial Acne Vulgaris May 2024 Acne Vulgaris Acne Vulgaris Clascoterone Vehicle cream 692 NCT06403488 Beni-Suef University Letrozole Dose Increments in PCOS Patients Resistant to Letrozole October 1, 2023 Polycystic Ovary Syndrome Letrozole ovulation PCOS Letrozole 2.5mg 102 Beni-suef university Hospital Beni-suef university Hospital Banī Suwayf Banī Suwayf Beni Suef 62521 62511 Egypt Egypt NCT06403475 Sheffield Teaching Hospitals NHS Foundation Trust Transcutaneous Vagus Nerve Stimulation for Language Recovery After Stroke April 29, 2024 Aphasia Chronic Stroke aphasia vagus nerve stimulation stroke transcutaneous vagus nerve stimulation Transcutaneous Vagus Nerve Stimulation Sham Transcutaneous Vagus Nerve Stimulation Computer Based Speech and Language Therapy (Step by Step) 36 University of Sheffield Sheffield S10 2HQ United Kingdom NCT06403462 Seoul National University Hospital Transversalis Fascia Plane Block for Iliac Bone Graft in Children May 2, 2024 Postoperative Pain, Acute transversalis fascial plane block transversus abdominis plane block 40 Seoul National University Children's Hospital Seoul 110-744 Korea, Republic of NCT06403449 Peking University The Effectiveness of Group-Delivered Guided Written Exposure Therapy for PTSD and Subclinical PTSD Among Chinese Adolescents : A Pilot Study May 1, 2024 PTSD PTSD adolescents randomized controlled trial Group-delivered guided written exposure therapy-revised version Waiting-List (WL) condition 40 Peking University Beijing Beijing 100871 China NCT06403436 TOLREMO therapeutics AG A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of TT125-802 in Subjects With Advanced Solid Tumors November 7, 2023 Advanced Solid Tumor Adult Solid Tumor Adult Disease Cancer TOLREMO Drug resistance TT125-802 Small molecule TT125-802 50 NEXT Oncology Hospital Vall d'Hebrón NEXT Madrid Ente Ospedaliero Cantonale Centre Hospitalier Universitaire Vaudois Barcelona Barcelona Madrid Bellinzona Lausanne 08023 08035 28223 6500 1890 Spain Spain Spain Switzerland Switzerland NCT06403423 Sykehuset Innlandet HF Screening for Aortic Aneurysms in Inland Norway May 14, 2024 Abdominal Aortic Aneurysm Erectile Dysfunction Quality of Life 240 Sykehuset Innlandet Hamar Norway NCT06403410 Istanbul Demiroglu Bilim University Delirium Prevention Guideline for Intensive Care Patients June 15, 2024 Delirium Nurse's Role delirium non-pharmacologic nursing intervention Delirium Prevention Guideline 160 Demiroğlu Bilim University İstanbul Şişli 34394 Turkey NCT06403397 Istanbul Demiroglu Bilim University Assessing the Impact of Monitor Maintenance Package Utilization June 15, 2024 Alarm Fatigue Patient Safety alarm fatigue Intensive care unit Nurse-driven monitoring bundle patient safety Experimental group: CEASE Care Package and Remember Me Tool 142 Demiroğlu Bilim University İstanbul Şişli 34394 Turkey NCT06403384 Karabuk University Vibration Therapy in Wheelchair Basketball Players August 1, 2021 Wheelchair Users Athletic Performance Disability Disabled Persons Athlete Disabled persons Exercise Pain Proprioception Upper extremity Vibration 13 Karabuk U Karabük Turkey NCT06403371 King Abdullah University Hospital The Effect of Fluoride Varnish on White Spot Lesion in Clear Aligner Orthodontic Patients June 1, 2023 White Spot Lesion Fluoride varnish Clear aligners White spot lesions Quantitative light induced fluorescence (QLF) Fluoride varnsh Normal saline 44 Postgraduate Teaching Clinics/JUST Irbid 22110 Jordan NCT06403358 Labomar SPA Study for Evaluation of Probiotics in the Re-equilibration of the Intestinal Microbiota, in Paediatric Age November 28, 2022 Diarrhea YOVIS BIMBI 43 Studio Pediatrico Dr. Gaetano Bottaro Gravina Di Catania Catania 95030 Italy NCT06403345 Indiana University A Green Activity Prescription Program for Hispanic/Latino (Latinx) Persons Living With Dementia April 29, 2024 Mild Cognitive Impairment Alzheimer Disease Green Activity Program 40 NCT06403332 Hospital Universitari Vall d'Hebron Research Institute Study of the Drivers of Late Diagnosis of Alcohol Related Diseases, Alone or in Combination With Metabolic Dysfunconal Associated Fatty Liver Disease, Implementation and Evaluation of Itnerventions to Reduce Its Burden. February 2, 2023 Alcohol-related Liver Disease Alcohol Use Disorder Metabolic and Alcohol Related/Associated Liver Disease Metabolic Disfunction Associated Steatotic Liver Disease brief intervention 350 Hospital Universitari Vall d'Hebron University Hospital Vall d'Hebron Barcelona Barcelona 08035 08035 Spain Spain NCT06403319 Hearing and Language Healthcare Center, China Medical University Hsinchu Hospital, Taiwan Otitis Media With Effusion and Type 2 Inflammation Diseases January 1, 2009 Otitis Media With Effusion 100622 NCT06403306 Tokat Gaziosmanpasa University Evaluation of Pulpotomy Success of Different Methods April 1, 2018 Pulpal Bleeding; Staining Primary Teeth Pulpotomy Ferric Sulfate (Viskostat; Ultradent, Utah, USA) Ankaferd Blood Stopper (Ankaferd Blood Stopper, Ankaferd Ilaç Kozmetik A.S, Istanbul, Turkey) Er,Cr:YSGG laser (Waterlase MD, Biolase, USA) 81 Tokat Gaziosmanpaşa University Tokat Turkey NCT06403293 Mustafa Kemal University Influence of Sonic Activation of Root Sealers on Post-Operative Pain January 16, 2023 Post Operative Pain Apical Periodontitis apical periodontitis post operative pain calcium silicate endoactivator Root canal treatment (AH Plus-NA) Root canal treatment (AH Plus-EA) Root canal treatment (BC-NA) Root canal treatment (BC-EA) 120 Mustafa Kemal University Hatay Antakya 31000 Turkey NCT06403280 Medical University of Graz The Effect of Alcohol on Common Tremor Syndromes May 2024 Essential Tremor Dystonia Parkinson Disease accelerometry alcohol responsiveness Alcoholic drink Placebo drink 45 Medical University of Graz Graz Styria 8010 Austria NCT06403267 NoNO Inc. NoNO-42 Trial in Acute Ischemic Stroke Patients Selected for Thrombolysis With or Without Endovascular Thrombectomy May 2024 Acute Ischemic Stroke Thrombolysis, Endovascular thrombectomy NoNO-42 Placebo 600 NCT06403254 I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio Evaluation of VSS Antibiotic Prophylaxis in Prosthetic Surgery (MRSA) September 20, 2022 Infection in Bone There isn't an intervention name because the study is observational and has only one group. 700 Istitutio Ortopedico Galeazzi Sede San Siro Milan Lumbardy 20148 Italy NCT06403241 Poznan University of Physical Education The Association Between Food Timing and Composition on Gastrointestinal Injury, Stress Hormone and Gastrointestinal Complains. May 1, 2023 Endothelial Dysfunction athlete's diet endotoxemia cortisol gut injury gut permeability exercise 2000 meter ergometer test 13 Poznan University of Physical Education, Faculty of Sport Sciences in Gorzow Gorzów Wielkopolski Lubuskie 66-400 Poland NCT06403228 Mersin Training and Research Hospital The Effect of Mindfulness Based Structured Nursing Interventions on Mental Health Parameters March 15, 2022 Mindfulness Mental Health Mindfulness Based Structured Nursing Interventions 40 Mersin University Mersin 33343 Turkey NCT06403215 Marmara University Effect of Chewing Gum and Drinking Fennel Tea September 11, 2017 Bowel Ileus Cesarean Section Complications Cesarean chewing gum fennel tea Bowel sounds Chewing gum group Fennel tea group Chewing gum+Fennel tea group Control group 120 Marmara University Istanbul 34854 Turkey NCT06403202 Lille Catholic University Prognostic Performance of a Chemogram in Patients With Bladder Cancer. August 23, 2022 Urinary Bladder Neoplasms Urinary Bladder Neoplasms Chemogram 60 Hôpital St Philibert Lomme 59160 France NCT06403189 Assistance Publique - Hôpitaux de Paris Choroid Plexus Dysfunction in Neurological Diseases July 1, 2024 Plexus Choroideus Metabolic Syndrome Biologic samples and MRI 65 CIC Neurosciences Paris 75013 France NCT06403176 First Affiliated Hospital of Zhejiang University Arteriovenous Plasma Multiomics in Patients With Disorders of Consciousness May 1, 2022 Disorders of Consciousness Transient Ischemic Attack Plasma metabolism No intervention 100 The First Affiliated Hospital of Zhejiang University Hanzhou Zhejiang 310003 China NCT06403163 Erasme University Hospital Transfusion Surveillance in Anaesthesia September 1, 2022 Transfusion Reaction Transfusion Related Complication Anesthesia Anesthesia; Shock Side Effect Fresh Blood Stool Blood Coagulation Disorder Blood Loss transfusion monitoring emergency situation shock fresh frozen plasma Transfusion 50000 Université libre de Bruxelles Anderlecht 1070 Belgium NCT06403150 Dhaka Medical College The Efficacy and Safety of Levetiracetam Versus Fosphenytoin in Convulsive Status Epilepticus May 15, 2023 Status Epilepticus Status Epilepticus Levetiracetam Fosphenytoin Levetiracetam Injection Fosphenytoin Injection 62 Dhaka Medical College Hospital Dhaka 1000 Bangladesh NCT06403137 Maastricht University Medical Center Plant Protein Blend and Milk Protein Supplements in Older Individuals May 20, 2024 Sarcopenia Skeletal Muscle Atrophy Protein Malnutrition Muscle protein synthesis Protein supplement Resistance exercise Standardized diet 42 NCT06403124 Chittagong Medical College Outcome of Operative Management of Posterior Wall of Acetabulum Fracture March 1, 2022 Posterior Wall of Acetabulum Fracture Posterior wall of acetabulum, operative management Open reduction and internal fixation 32 Chittagong Medical College Chittagong 4203 Bangladesh NCT06403111 Changzhou No.2 People's Hospital FMT+Immunotherapy+Chemotherapy as First-line Treatment for Driver-gene Negative Advanced NSCLC June 1, 2024 Non-small Cell Lung Cancer Fecal Microbiota Transplantation (FMT)+chemotherapy+immunotherapy 62 NCT06403098 Florida State University The Effects of External Nasal Dilator Strips on Sleep and Cardiovascular Health May 2, 2024 Healthy External Nasal Dilator Strip 30 Cardiovascular and Applied Physiology Laboratory Tallahassee Florida 32306 United States NCT06403085 Firat University Proprioceptive Exercises in Stringed Instrument Performers May 3, 2024 String Instrument Performers proprioceptive education performance musicians Study group 40 Hasan Akbey Elazığ 23100 Turkey NCT06403072 Beni-Suef University (GI-RADS) in Preoperative Evaluation of Adnexal Masses June 1, 2021 Ovarian Cancer Gynecologic Imaging-Reporting and Data System Adnexal Masses Ovarian cancer The Gynecologic Imaging-Reporting and Data System (GI-RADS) 100 Beni-suef university Hospital Banī Suwayf 62511 Egypt NCT06403059 Beni-Suef University Cervical Length and Uterocervical Angle as Predictors of Spontaneous Preterm Birth October 15, 2023 Preterm Pregnancy preterm delivery Cervical Length Uterocervical Angle Cervical Length Uterocervical Angle 263 Beni-suef university Hospital Banī Suwayf 62511 Egypt NCT06403046 Beni-Suef University Effect of Intra-articular Injection of Tenoxicam or Meloxicam in TMJ Anterior Disc Displacement With Reduction June 1, 2024 Temporomandibular Joint Disc Displacement, With Reduction intraarticular injection 20 NCT06403033 Damascus University Mini-implant-supported Twin-Block in Treating Patients With Class II Division 1 Malocclusion September 10, 2022 Orthodontic Appliance Complication Malocclusion, Angle Class II, Division 1 Mini-implant-supported Twin-Block Twin-Block 41 Department of Orthodontics, Faculty of Dentistry, University of Damsacus Damascus DM20 HAJ72 Syrian Arab Republic NCT06403020 Fayoum University Hospital Ultrasound-guided Quadratus Lumborum Block Versus Rectus Sheath Block May 3, 2024 Quadratus Lumborum Block and Rectus Sheath Block quadratus lumborum block rectus sheath block Block 46 Fayoum University Hospital Fayoum 63511 Egypt NCT06403007 York University Tackling Two of the Most Important Unresolved Tasks in Reading Intervention August 31, 2024 Dyslexia, Developmental reading intervention phonics morphology set-for-variability dyslexia prevention Phonics plus morphology Phonics plus set-for-variability 637 NCT06402994 Universitaire Ziekenhuizen KU Leuven Automated Measures of Speech Intelligibility Using Brain Wave Recordings February 23, 2024 Hearing Disorders in Children Hearing Loss speech intelligibility EEG objective measure hearing loss hearing aid benefit children Electrophysiological experiment Speech audiometry 90 CAR Sint-Lievenspoort UZ Leuven CAR Overleie KOCA vzw Gent Leuven Kortrijk Antwerpen Oost-Vlaanderen Vlaams-Brabant West-Vlaanderen 9000 3000 8500 2018 Belgium Belgium Belgium Belgium NCT06402981 Zhejiang University A Clinical Study on the Analysis of Risk Factors for the Occurrence of PD-1/PD-L1 Inhibitor-associated Liver Injury in Lung Cancer Patients January 1, 2020 Immune Checkpoint Inhibitors Liver Injury PD-1/PD-L1 inhibitor lung cancer High risk prediction model for liver injury 2000 The First Affiliated Hospital, Zhejiang University School of Medicine Hangzhou Zhejiang China NCT06402968 Zeenat Qureshi Stroke Institute Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage June 1, 2024 Intracerebral Hemorrhage Stroke Hypertension Clevidipine Injection Alternate IV Antihypertensive Regimen 1000 NCT06402955 Yale University Imaging Depression in Parkinson's Disease May 2024 Parkinson's Disease Major Depressive Disorder Imaging 11C-UCB-J 120 NCT06402942 Lokman Hekim Üniversitesi Gamified Occupational Therapy for Adolescents With Duchenne Muscular Dystrophy June 1, 2024 Duchenne Muscular Dystrophy Gamification Occupational Therapy Gamified occupational therapy programme Classic occupational therapy programme 20 Lokman Hekim University Ankara 06510 Turkey NCT06402929 Lakehead University Honest, Open, Proud - College for Post-Secondary Students With Mental Health Challenges March 17, 2023 Stigmatization Mental Health Issue Disclosure Mental Illness Stigma Self-Stigma Post-Secondary Students Group Intervention Disclosure Honest Open Proud - College (HOP-C) 100 Lakehead University Thunder Bay Ontario Canada NCT06402916 University of Reading The Acute Effects of Blueberries on Cognition and Mood in the Postpartum May 20, 2024 Mood Parents Healthy Blueberry drink Placebo drink 60 NCT06402903 University of Oviedo Physiotherapy in Patients in a Cardiac Intensive Care Unit May 6, 2024 Cardiac Surgery Patients Physiotherapy Intensive Care Unit Postoperative complications prevention Cardiac surgery Observation 110 University of Oviedo Oviedo Asturias 33006 Spain NCT06402890 Liverpool John Moores University Resistance Training and Hydrolyzed Collagen Supplementation in Middle-aged Adults July 1, 2021 Diet Food Nutrition Hydrolyzed collagen Middle-age Resistance training Tendon properties Resistance training with collagen supplementation 42 Dr Rob Erskine Liverpool L3 3AF United Kingdom NCT06402877 Izmir Katip Celebi University Evaluation of Salivary Adseverin, 1-Alpha Defensin and sRANKL Levels of Individuals With Different Periodontal Diseases April 26, 2024 Periodontal Diseases Saliva obtaining 60 Izmir Katip Çelebi University Department of Periodontology İzmir Çiğli 35640 Turkey NCT06402864 Gustave Roussy, Cancer Campus, Grand Paris Evaluation Contact X-ray Brachytherapy for Rectal Preservation in Intermediate Substage Rectal Adenocarcinoma March 26, 2024 Adult With Intermediate Low or Mid Rectal Adenocarcinoma contact X-ray brachytherapy (CXB) 212 Institut Gustave Roussy Villejuif 94805 France NCT06402851 Hospital Sirio-Libanes Vitamin K AntagonISt, Factor Xa Inhibitor Or Nothing In Atrial Fibrillation And DIalytic End-stage Renal DiseasE (VISIONAIRE) July 2024 Atrium; Fibrillation Chronic Kidney Diseases atrial fibrillation atrial flutter oral anticoagulation dialysis Oral anticoagulant 1500 NCT06402838 Hoffmann-La Roche A Study to Evaluate the Safety and Biomarker Effects of RO7269162 in Participants at Risk for or at the Prodromal Stage of Alzheimer's Disease (AD) May 2, 2024 Alzheimer's Disease RO7269162 Placebo 245 Groupement Hospitalier Est - Hôpital Neurologique; Neurologie A (U502) Hôpital Lariboisière Gerontopole; Centre de Recherche clinique Ajou University Medical Center Gachon University Gil Medical Center Inha University Hospital Bron cedex Paris Toulouse Gyeonggi-do Incheon Incheon 69677 75010 31059 16499 21565 22332 France France France Korea, Republic of Korea, Republic of Korea, Republic of NCT06402825 Université de Sherbrooke Follow-up of Children Born From a Preconception Lifestyle Intervention in Women With Obesity and Infertility November 13, 2023 Obesity, Childhood Lifestyle Intervention Preconception Care Obesity Maternal obesity Healthy lifestyle Preconception care Fetal programming Fit-for-Fertility program 50 Centre hospitalier universitaire de Sherbrooke Sherbrooke Quebec J1H 5N4 Canada NCT06402812 University Medical Center Groningen The Perceived Mismatch Between Dose Recommendations of PKI's and the Clinical Practice February 6, 2024 Cancer Interview 18 University Medical Center Groningen Groningen 9713 GZ Netherlands NCT06402799 University of Copenhagen Home-based E-biking Intervention Among Adolescents With Cerebral Palsy February 12, 2024 Cerebral Palsy Home-based e-biking monitoring adolescents cerebral palsy feasibility Home-based E-biking 25 Lisbeth Larsen Copenhagen 2200 Denmark NCT06402786 University of Auckland, New Zealand First-in-human Trial of Home Brain Pressure Measured Using Kitea ICP Sensor, Placed During Hydrocephalus Shunt Surgery. May 2024 Hydrocephalus Intracranial Pressure Kitea ICP Sensor 20 Auckland City Hospital Auckland New Zealand NCT06402773 Signati Medical Inc A Safety Study in Human Subjects Evaluating the Use of the Signati System for Vasectomy April 5, 2024 Vasectomy The Signati Separo™ Vessel Sealing System 8 LSU Health New Orleans Louisiana 70112 United States NCT06402760 Shanghai Yueyang Integrated Medicine Hospital Comprehensive Intervention of Diabetes and Psoriasis Comorbidity Prevention and Control July 1, 2024 Psoriasis Diabetes TCM comprehensive treatment Western medicine 300 NCT06402747 Seoul National University Bundang Hospital Clopidogrel Versus Cilostazol on Vessels April 16, 2024 Type 2 Diabetes Atherosclerosis Clopidogrel Cilostazol 120 Seoul National University Bundang Hospital Seongnam-si Gyeonggi-do 13620 Korea, Republic of NCT06402734 Hacettepe University Effects of Gluten-Free Diet on Nutritional Status in Celiac Patients October 15, 2018 Celiac Disease celiac disease inflammation interferon-gamma interleukin-15 Adherence to Gluten Free Diet 52 Hacettepe University Nutrition and Dietetics Department Ankara 06100 Turkey NCT06402721 Bayer A Study to Learn About How BAY 3283142 Moves Into, Through, and Out of the Body After a Single Dose in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function May 13, 2024 Chronic Kidney Disease Hepatic Impairment CKD BAY3283142 32 NCT06402708 Fudan University Postoperative Adjuvant Chemotherapy for Thymic Cancer (FUSCC-Thymic 3) April 9, 2024 Thymic Carcinoma thymic carcinoma adjuvant treatment radiotherapy chemotherapy Chemotherapy Radiotherapy 172 Fudan University Shanghai Cancer Center Shanghai Shanghai 212013 China NCT06402695 Fondazione Policlinico Universitario Agostino Gemelli IRCCS Observational Study on GEP-and Pulm-NET Treated at FPG September 15, 2023 Neuroendocrine Tumors Gep Net Pulmonary Neuroendocrine Neoplasm 650 Fondazione Policlinico Universitario Agostino Gemelli - IRCCS Rome 00168 Italy NCT06402682 Fondation Lenval Management of Esophageal Atresia With Right Aortic Arch: Is the Side of Approach Important? March 15, 2024 Right Aortic Arch Right approach Left approach 19 Fondation Lenval Nice 06200 France NCT06402669 Arrowhead Regional Medical Center Extremity Trauma At a Level 1 Trauma Center January 1, 2022 Trauma Injury Trauma Blunt Vascular Trauma Packed Red Blood Cell Administration 20000 Arrowhead Regional Medical Center Colton California 92324 United States NCT06402656 Azienda Ospedaliero-Universitaria Careggi Comparison of Customized and Standard Facemasks for Early Treatment of Class III Malocclusion May 6, 2024 Malocclusion, Angle Class III Extraoral Traction Appliances Customized facemask Standard facemask 24 NCT06402643 Instituto de Oftalmología Fundación Conde de Valenciana Comparison of Recurrence Between Mini-SLET and Limbal-Conjunctival Autograft Techniques in Primary Pterygium June 22, 2024 Pterygium of Right Eye Pterygium of Left Eye Pterygium of Both Eyes Pterygium Pterygium, Mini-SLET Conjunctival-Limbal autograft Pterygium Excision 68 Instituto de oftalmología conde de Valenciana Mexico City 06800 Mexico NCT06402630 Soterios Ltd A Phase 2 Placebo Controlled, Clinical Trial Designed to Assess the Efficacy, Safety and Dose Response Characterisation of STS01 for the Treatment of Mild-moderate Alopecia Areata (AA) March 23, 2022 Alopecia Areata alopecia areata alopecia areata aa autoimmune hair loss hair autoimmune hair follicle STS01 Placebo 158 Queen Margaret Hospital St Lukes Hospital Royal Alexandra Children's Hospital University Hospital Coventry & Warwickshire Queen Elizabeth University Hospital Gloucestershire Royal Hospital Queen Anne Street Medical Centre Limited Norfolk and Norwich University Hospital Salford Royal Hospital Glasgow Bradford Brighton Coventry Glasgow Gloucester London Norwich Salford Dunfirmline Little Horton Lane KY12 0SU BD5 0NA BN2 5BE CV2 2DX G51 4TF GL1 3NN W1G 8HU NR4 7UY M6 8HD United Kingdom United Kingdom United Kingdom United Kingdom United Kingdom United Kingdom United Kingdom United Kingdom United Kingdom NCT06402617 Imperial College London Ablation of Focal Activation in Atrial Fibrillation April 30, 2024 Atrial Fibrillation Atrial Fibrillation, Persistent Arrhythmia Arrhythmias, Cardiac Cardiac Arrhythmia ablation electrophysiology mapping local activation time pulmonary vein isolation atrial fibrillation cycle length Pulmonary vein isolation RETRO-Mapping without adjunctive ablation Adjunctive ablation guided by RETRO-Mapping 110 Hammersmith Hospital London W12 0HS United Kingdom NCT06402604 Radboud University Medical Center Stress Reduction in Formerly Preeclamptic Women; Sofa or Sports March 21, 2022 Preeclampsia Stress, Psychological Stress, Physiological Sports Physical Therapy Mindfulness Based Stress Reduction Hair cortisol Preeclampsia Stress Aerobic sports training Aerobic exercise training Mindfulness Based Stress Reduction training 84 Joris J.A. van Esch Maastricht UMC+ Nijmegen Maastricht Gelderland P.O. Box 5800 6500HB 6202AZ Netherlands Netherlands NCT06402591 Radboud University Medical Center Results of Extended Versus Single Dose Antibiotic Prophylaxis In Orthopedic Revision Arthroplasty in Nijmegen. January 1, 2019 Infection Prosthesis Hip and Knee Infection, Prosthesis Related Joint Infection Infection, Surgical Site Surgical Site Infection Infection Pro Cefazolin 751 Radboudumc Nijmegen Gelderland Netherlands NCT06402578 Queen Margaret University A 12-week Digital Physical Activity Programme, With or Without Physical Education Support for Type 2 Diabetes Patients. June 2024 Diabetes Mellitus, Type 2 HbA1c Cholesterol Resting Heart Rate HbA1c testing 60 Queen Margret University Edinburgh Edinburgh Musselburgh EH21 6UU United Kingdom NCT06402565 NOxy Health Products, LLC NOX1416 in Treatment of Chronic Non-Healing Diabetic Foot Ulcers May 15, 2024 Diabetic Foot Ulcer NOX1416 plus SOC Placebo plus SOC 40 SerenaGroup Omaha SACMH Wound Center SerenaGroup Monroeville Omaha Kittanning Monroeville Nebraska Pennsylvania Pennsylvania 68114 16210 15146 United States United States United States NCT06402552 Chang Gung Memorial Hospital Comparing Bp-MRI and Mp-MRI for Prostate Cancer Screening Accuracy May 1, 2024 Randomized Controlled Trial Prostate Cancer Magnetic Resonance Imaging bp-MRI prostate mp-MRI prostate 370 Chang Gung Memorial Hospital, Linkou Taoyuan city 333 Taiwan NCT06402539 Selcuk University Program Based on the Family-Centered Empowerment Model on Total Knee Prosthesis Patients and Their Caregivers December 1, 2023 Caregiver total knee arthroplasty Family Centered Empowerment Model caregivers care burden self-efficacy coping with stress caregiving competence family-centered empowerment program 61 Selçuk University Faculty of Medicine Hospital Konya Selçuklu 42130 Turkey NCT06402526 McGill University Health Centre/Research Institute of the McGill University Health Centre Evaluating the Efficacy of a Mobile Epilepsy Education Application May 1, 2024 Epilepsy Epilepsy in Children Anxiety Knowledge, Attitudes, Practice Epilepsy Mobile application Education Anxiety Knowledge Parents/Caregivers Mobile Epilepsy Education Package Standard care consisting of epilepsy education 72 Montreal Children's Hospital Research Institute of the McGill University Health Centre Montréal Montréal Quebec Quebec H4A 3J1 H4A 3J1 Canada Canada NCT06402513 AbbVie A Study in Healthy Adult Participants to Assess the Pharmacokinetics, Immunogenicity, Safety, and Tolerability of a Ravagalimab Subcutaneous Formulation in a Pre-Filled Syringe June 24, 2024 Healthy Volunteers Healthy Volunteers Ravagalimab ABBV-323 Ravagalimab 12 NCT06402500 King Abdullah University Hospital Color Masking Potential of Bioactive and ICON Materials December 1, 2023 White Spot Lesion of Tooth Resin infiltration Incipient lesion bioactive material ICON infiltration resin Icon Infiltrant Bioactive infiltrant 75 Jordan University of Science and Technology Irbid 21110 Jordan NCT06402487 Salzburger Landeskliniken Propionic Acid in Multiple Sclerosis May 1, 2024 Multiple Sclerosis Multiple Sclerosis Propionic Acid Progression Disability Fatigue Propionic acid 1000 mg capsule Placebo 100 Salzburger Landeskliniken Salzburg 5020 Austria NCT06402474 Istinye University Effect of Two Different Surgical Positions on Pulmonary Functions in Laparoscopic Gastrectomies May 1, 2024 Pulmonary Pathology sunbed position 50 Istinye Üniversity Istanbul Merkez Mahallesi 34250 Turkey NCT06402461 Canterbury Christ Church University Comparing Random Allocation and Allocation by Preference to Mindfulness Practice June 2024 Healthy Mindfulness of the breath Mindfulness of sounds Audiobook control 252 Salomons Institute for Applied Psychology, Canterbury Christ Church University Tunbridge Wells Kent TN1 2YG United Kingdom NCT06402448 Cairo University Prevalence of Muscle and Nerve and Joint Pain February 1, 2024 Muscle Pain Joint Pain Nerve Pain muscle pain , joint pain and nerve pain. 300 Faculty of Physical Therapy Cairo University Giza 12613 Egypt NCT06402435 Hubei Cancer Hospital SBRT, Chemotherapy, and AK112 Neoadjuvant Therapy for Luminal-type Breast Cancer September 1, 2024 Breast Cancer Lvonescimab (AK112) 50 NCT06402422 The Hong Kong Polytechnic University Vulnerability Markers for Depression October 8, 2023 Major Depressive Disorder Remission Major Depressive Disorder Healthy Theta-burst stimulation Concurrent TBS/fNIRS Verbal fluency task Theta-burst stimulation 160 The Hong Kong Polytechnic University Hong Kong Hong Kong NCT06402409 Aalborg University Hospital Exploring Multimorbidity in Patients With Spinal Pain May 15, 2024 Back Pain Neck Pain Comorbidities and Coexisting Conditions Multimorbidity Comorbidities Comorbidity Neck Pain Back Pain Spinal pain 2000 NCT06402396 University Hospital Bispebjerg and Frederiksberg Assessing Pain by the painDETECT Questionnaire (PDQ) January 2013 Inflammatory Arthritis Spondylarthropathies Rheumatoid Arthritis Psoriatic Arthritis Drug survival Pain phenotypes PainDETECT Questionnaire Inflammatory Arthritis bDMARDS 7056 NCT06402383 Queen's University Supporting the National Expansion of HPV-based Cervical Cancer Screening in Tanzania Among Women Living With HIV June 2024 Cervical Cancer cervical cancer cancer prevention screening Vaccination Provision Vaccination Provision 2 2000 NCT06402370 University Hospital, Ghent Amyloid PET in Patients With Mild Cognitive Impairment and Early Dementia May 2024 MCI PET scan 50 Van Weehaeghe D Gent 9000 Belgium NCT06402357 University of Florida High Intensity Focused Ultrasound in Prostate Cancer August 2024 Prostate Cancer prostate cancer high intensity focused ultrasound focal therapy Focal One high intensity focused ultrasound device 25 University of Florida Gainesville Florida 32608 United States NCT06402344 Hospital Israelita Albert Einstein Gestrinone and Endothelial Function in Young Women May 27, 2024 Hormones; Abuse Cardiovascular Diseases Hormonal implant Gestrinone Endothelial function Hormonal implant 90 Hospital Israelita Albert Einstein São Paulo 05652-900 Brazil NCT06402331 Fusion Pharmaceuticals Inc. FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC) March 5, 2024 Metastatic Castration-resistant Prostate Cancer mCRPC 225Ac-PSMA-I&T Radioligand therapy FPI-2265 60 XCancer Omaha Nebraska 68130 United States NCT06402318 The Geneva Foundation Passive Detection- SARS-CoV-2 A&M Breathalyzer (PROTECT Kiosk) for Operational Medicine December 27, 2023 COVID-19 SARS CoV 2 Virus COVID-19 Pneumonia COVID-19 Respiratory Infection COVID-19 Acute Respiratory Distress Syndrome Breathalyzer, COVID-19 detection, Diagnostic Product, Pulmonary, PROTECT Kiosk, Passive Detection A&M Breathalyzer PROTECT Kiosk 100 Brooke Army Medical Center Fort Sam Houston Texas 78234 United States NCT06402305 Sohag University Lipid Profile and Ultrasound Findings in Patients With Pancreaticobiliary Diseases May 2, 2024 Lipid Profile and Ultrasound Findings in Patients With Pancreaticobiliary Diseases Lipid profile 200 Sohag university Sohag Egypt NCT06402292 Federal University of São Paulo Surgical Treatment of Osteoarticular Infections Using Bioactive Bone Substitute September 1, 2024 Osteomyelitis Infections Fracture Antibiotics infection osteomyelitis fracture local antibiotics OSTEOMYELITIS SURGICAL TREATMENT WITH LOCAL ANTIBIOTICS AND PEROSSAL 25 NCT06402279 Efferon JSC Hemoperfusion Efferon СT for the Extremely Severe Form of COVID-19 October 1, 2020 COVID-19 COVID-19 mesoporous styrene-divinylbenzene copolymer cytokines adsorption hemoperfusion Efferon CT 130 Alexey Yakovlev Nizhny Novgorod Russian Federation NCT06402266 University of Aarhus Simultaneous tDCS and Computerised Gamified Short-term Memory Task Feasibility July 4, 2022 Genetic Predisposition Apolipoprotein E4 Cognitive reserve Gamified cognitive training Brain stimulation tDCS Technical compatibility tDCS 13 Aarhus University, Centre for Functionally Integrative Neuroscience Aarhus Aarhus N 8200 Denmark NCT06402253 New York University A Music and Visual Arts Digital Intervention in Teenagers to Promote Healthy Engagement With Social Media. March 1, 2024 Healthy Subjects Mental Health Issue Mental health Adolescents Social media Music Neuroarts Cognition Brain imaging Music composition / edition Photography composition / edition 90 Fort Hamilton High School Faculty of Arts & Science, Psychology Department - New York University Brooklyn New York New York New York 11209 10012 United States United States NCT06402240 University of Windsor The Pocket Skills Adjunct Project January 1, 2024 Substance Use Disorders Alcohol Use Disorder Depression Anxiety dialectical behavior therapy substance use disorders internet-delivered adjunct intervention alcohol use disorder Dialectical Behavior Therapy 30 Centre for Addiction and Mental Health Toronto Ontario M6J 1H1 Canada NCT06402227 National Yang Ming University Effectiveness of Board Game on Improving Elementary School Students' Infection Control November 1, 2023 Knowledge of Infection Control Attitude of Infection Control Behavioral Intentions of Infection Control Gamification Child Communicable Diseases Theory of Planned Behavior gamified instruction conventional lesson lecture 310 National Yang Ming University Taipei 112 Taiwan NCT06402214 Fondazione Policlinico Universitario Agostino Gemelli IRCCS The 'Lombard Effect' in Patients Affected by Adductor Laryngeal Dystonia May 1, 2024 Adductor Spasmodic Dysphonia laryngeal dystonia spasmodic dysphonia Lombard effect auditory system Lombard test 18 Fondazione Policlinico Universitario A. Gemelli IRCCS Roma 00168 Italy NCT06402201 CDR-Life AG First in Human Study of CDR404 in HLA-A*02:01 Participants With MAGE-A4 Expressing Solid Tumors May 15, 2024 Select Advanced Solid Tumors CDR404 42 NCT06402188 Averto Medical, Inc. ColoSeal™ ICD System Safety and Feasibility Study June 5, 2023 Colorectal Cancer Colon anastomosis Rectosigmoid cancer resection Ostomy Colon diversion ColoSeal ICD Device 15 Israeli-Georgian Medical Research Clinic Healthycore National Cancer Institute Tbilisi Tashkent 0112 Georgia Uzbekistan NCT06402175 Assiut University Characteristics and Outcomes of Patients With Hematological Malignancies May 1, 2024 Haematologic Neoplasm follow up 100 NCT06402162 Ankara University The Effect of Core Stability Exercises on Pain, Muscle Strength, and Muscle Architecture in Tennis Players With Rotator Cuff Lesions May 1, 2023 Exercise Muscle Weakness Rotator Cuff Injuries muscle thickness, fiber length, pennation angle, pain exercise 40 Tennis Club Ankara Turkey NCT06402149 Ankara City Hospital Bilkent Comparison of 2 Different Methods in Infraclavicular Block March 10, 2023 Postoperative Pain Nerve Block Analgesics infraclavicular block VAS (Visual Analogue Scale) score dexamethasone dexamethasone 60 Ankara Bilkent City Hospital Ankara 06800 Turkey NCT06402136 Traws Pharma, Inc. Evaluation Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of 83-0060 in Healthy Volunteers April 15, 2024 Healthy Volunteers Only 83-0060 Placebo 64 Scientia Clinical Research Sydney Greater Sydney Area NSW 2031 Australia NCT06402123 Tisento Therapeutics A Phase 2b Study of Zagociguat in Patients With MELAS June 1, 2024 Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome) MELAS zagociguat 15mg zagociguat 30mg Placebo 36 UC San Diego - Altman Clinical and Translational Research Institute Children's Hospital of Colorado Children's National Rare Disease Research Johns Hopkins University School of Medicine Massachusetts General Hospital Mayo Clinic Rochester Columbia University Irving Medical Center Mount Sinai - Ichan School of Medicine Akron Children's Hospital Children's Hospital of Philadelphia University of Pittsburgh Baylor College of Medicine University of Texas Medical School at Houston Neuroscience Research Australia Royal Melbourne Hospital Winnipeg Children's Hospital University Hospital Bonn Ludwig-Maximilians-University of Munich Neurologic Institute Carlo Besta of Milan University of Pisa Neurological Clinic Fondazione Policlinico Universitario Agostino Gemelli UCL Queen Square Institute of Neurology Newcastle University La Jolla Aurora Washington Atlanta Baltimore Boston Rochester New York New York Akron Philadelphia Pittsburgh Houston Houston Sydney Melbourne Winnipeg Bonn Munich Milan Pisa Roma London Newcastle Upon Tyne California Colorado District of Columbia Georgia Maryland Massachusetts Minnesota New York New York Ohio Pennsylvania Pennsylvania Texas Texas New South Wales Victoria 92037 80045 20010 30329 21287 02114 55905 10027 10029 44308 19104 15260 77030 77030 NSW 2031 3052 R3E 0Z3 53127 80336 20133 56100 00168 WC1N 3BG NE14LP United States United States United States United States United States United States United States United States United States United States United States United States United States United States Australia Australia Canada Germany Germany Italy Italy Italy United Kingdom United Kingdom NCT06402110 Tanta University Femoral Triangle Block Versus Adductor Canal Block in Arthroscopic Anterior Cruciate Ligament Reconstruction May 7, 2024 Femoral Triangle Block Adductor Canal Block Anterior Cruciate Ligament Reconstruction Femoral Triangle Block Adductor Canal Block 70 Tanta University Tanta El-Gharbia 31527 Egypt NCT06402097 St. Antonius Hospital TRIP-patch vs Duplex June 5, 2020 Erectile Dysfunction rigiscan erectile dysfunction 20 St Antonius Hospital Nieuwegein Utrecht 3435CM Netherlands NCT06402084 Sohag University The Relationship Between Fatty Liver and Breast Cancer May 2, 2024 The Relationship Between Fatty Liver and Breast Cancer abdominal ultrasound 100 Sohag university Hospital Sohag Egypt NCT06402071 Sohag University Clinical Value of the Developed Scoring Systems for Predicting Spontaneous Bacterial Peritonitis in Cirrhotic Ascites May 1, 2024 Cirrhotic Ascitic Patients Ascitic fluid study 100 Sohag university hospitals Sohag Egypt NCT06402058 Samyang Biopharmaceuticals Corporation A Study Comparing DMSB01 and Rejuran® for Temporary Crow's Feet Lines Improvement June 10, 2024 Crow's Feet Lines DMSB01 Rejuran® 60 NCT06402045 Cairo University Assessment of the Occlusal Characteristics and Orthodontic Treatment Needs for Egyptian Children( 6-12)years Old July 1, 2024 Occlusion 70 NCT06402032 Cairo University Clinical and Histological Evaluation of Hesperidin as a Direct Pulp Capping Material September 1, 2022 Pulp Exposure, Dental Dental Pulp Capping Hesperidin Mineral Trioxide Aggregate (MTA) 32 Faculty of Dentistry Cairo University Cairo Egypt NCT06402019 Benha University Dexmedetomidine Infusion Impact on Chronic Pain Patients March 1, 2023 Chronic Pain Dexmedetomidine in 0.9 % NaCl 20 Mcg/5 mL (4 Mcg/mL) INTRAVEN SYRINGE (ML) normal saline 100 Benha university Banhā Qalyoubia 13511 Egypt NCT06402006 Ain Shams University A Comparative Study Between Ultrasound Guided Erector Spinae Plane Block and Combined Ultrasound Guided Pericapsular Nerve Group and Lateral Femoral Nerve Block Following Total Hip Arthroplasty May 2024 Post Operative Pain PENG block LFCN block ESP block 50 NCT06401993 The Third Affiliated hospital of Zhejiang Chinese Medical University Peripheral-central Correlation Study on the Treatment of Chronic Tinnitus With "Dao qi Tong Luo" Based on the Theory of "Connecting the Two Ears to the Brain" May 2024 Tinnitus Acupuncture Fnirs Tinnitus ABR The "dao qi tong luo" group The acupuncture group 87 The Third Affiliated Hospital of Zhejiang Chinese Medical University Hangzhou 310000 China NCT06401980 Swiss Group for Clinical Cancer Research Darolutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC) August 2024 Metastatic Castration-resistant Prostate Cancer Metastatic Castration-Resistant Prostate Cancer mCRPC Darolutamide phase II trial Darolutamide Standard of care 162 Kantonsspital Baden Istituto Oncologico della Svizzera Italiana (IOSI) Inselspital Kantonsspital Graubuenden Hôpitaux Universitaires Genève HUG Centre Hospitalier Universitaire Vaudois CHUV Kantonsspital St. Gallen Kantonsspital Winterthur UniversitaetsSpital Zuerich OnkoZentrum Zürich - Standort Seefeld Stadtspital Triemli Zürich Baden Bellinzona Bern Chur Genève Lausanne St. Gallen Winterthur Zurich Zürich Zürich 5404 6500 7000 1211 CH-1011 CH-8400 8091 8038 8063 Switzerland Switzerland Switzerland Switzerland Switzerland Switzerland Switzerland Switzerland Switzerland Switzerland Switzerland NCT06401967 Pivot Health Technologies Inc. Study of a Smartphone-Based Alcohol Reduction Program June 2024 Alcohol Use, Unspecified alcohol reduction digital health mobile apps health promotion Pivot Clear BACtrack breathalyzer 100 Pivot Health Technologies, Inc. San Carlos California 94070 United States NCT06401954 National Taiwan University Hospital High-Intensity Focused Electromagnetic Therapy Combined With Foot Core Training for Pronated Foot May 15, 2024 Flexible Flatfoot pronated foot foot core system dynamic foot function high-intensity focused electromagnetic therapy foot core training High-intensity focused electromagnetic therapy Foot core training Sham high-intensity focused electromagnetic therapy 30 National Taiwan University Hospital Taipei Taiwan NCT06401941 Nicolaus Copernicus University Selected Lysosomal Enzyme Activities and the Oxidant-antioxidant Balance in Hyperbaric Oxygen Condition. April 26, 2016 Hyperbaric Oxygenation Oxygen Toxicity Antioxidants Oxidative Stress Hyperbaric Oxygen Therapy 78 Department of Medical Biology and Biochemistry, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Karlowicza 24, 85-092 Bydgoszcz, Poland Bydgoszcz Kujawsko-Pomorskie 85-092 Poland NCT06401928 The National Brain Mapping Laboratory (NBML) Electrical Brain Stimulation for Treatment of Secondary Symptoms in Multiple Sclerosis February 28, 2023 Multiple Sclerosis transcranial direct current stimulation transcranial direct current stimulation combined with cognitive training transcranial direct current stimulation 53 Multiple Sclerosis Association of Guilan Rasht Giulan Iran, Islamic Republic of NCT06401915 National Cheng-Kung University Hospital Intelligent Assistive Technologies for Dementia May 10, 2023 Healthy Adult Dementia Care Hand rehabilitation HAAL dashboard 18 National Cheng Kung University Tainan Taiwan NCT06401902 Institut Mutualiste Montsouris Diabetes and Risk of Ischemic Stroke. January 1, 1990 Carotid Stenosis diabetes ischemic stroke cerebral hemorrhage hypoperfusion hyperperfusion carotid clamping 3739 Mutualist Montsouris Institute Paris Ile De France 75014 France NCT06401889 Mayo Clinic Enhancing Skin Appearance and Quality of Life in Breast Cancer Survivors on Aromatase Inhibitor Therapy June 1, 2024 Anatomic Stage 0 Breast Cancer AJCC v8 Anatomic Stage I Breast Cancer AJCC v8 Anatomic Stage II Breast Cancer AJCC v8 Anatomic Stage III Breast Cancer AJCC v8 Breast Adenocarcinoma Estrogen Receptor-Positive Breast Carcinoma Progesterone Receptor-Positive Breast Carcinoma Non-Interventional Study 50 Mayo Clinic in Florida Jacksonville Florida 32224-9980 United States NCT06401876 Mayo Clinic Extracellular Vesicle Cargo in Obesity and Type 2 Diabetes May 2, 2024 Glucose Intolerance Insulin Resistance Diabetes Bariatric Surgical Procedure 60 Mayo Clinic in Florida Jacksonville Florida 32224 United States NCT06401863 University of Utah Shared Decision for Drug Interactions in Oral Anticoagulation October 1, 2023 Anticoagulants Drug Interactions Oral anticoagulants Drug interactions Gastrointestinal hemorrhage Shared Decision Making Shared Decision Making Tool 3691 University of Colorado. School of Medicine Vanderbilt University University of Utah Denver Nashville Salt Lake City Colorado Tennessee Utah 80045 37235 84112 United States United States United States NCT06401850 Marmara University Polycystic Ovary Syndrome and Education October 26, 2023 Quality of Life Polycystic Ovary Syndrome Quality of Life Education Education Group Control Group 70 Marmara University Istanbul 34854 Turkey NCT06401837 China Medical University Hospital Acupressure Therapy on Post-stroke Fatigue, Depression, and Sleep Disturbances in Ischemic Stroke Patients September 14, 2023 Inflammatory Cytokine Circadian Rhythm Acupressure Post-stroke Fatigue Sleep Ischemic Stroke Circadian based acupressure application 78 China Medical University Hospital Taichung East Branch China Medical University Hospital Taichung Taichung 401005 40447 Taiwan Taiwan NCT06401824 Maastricht University Medical Center Sacituzumab Govitecan and Bevacizumab for NSCLC Brain Metastases July 1, 2024 NSCLC Stage IV Brain Metastases, Adult non small cell lung cancer brain metastases bevacizumab sacituzumab govitecan Sacituzumab Govitecan-Hziy 180 MG plus bevacizumab 25 NKI-AvL University Medical Center Groningen Maastricht University Medical Center Amsterdam Groningen Maastricht Netherlands Netherlands Netherlands NCT06401811 Kahramanmaras Sutcu Imam University Reliability, Validity, and Responsiveness of the Turkish Version of Eating Assessment Tool-10 for Patients With Primer Sjögren's Syndrome May 30, 2024 Sjogren's Syndrome Primer Sjogren's Syndrome swallowing disorder 100 NCT06401798 Kafrelsheikh University Locally Delivered Whey Protein Nanoparticles Gel in Stage II Grade B Periodontitis May 5, 2024 Periodontitis Chronic Localized Slight placebo gel CWP gel NCWP gel 45 oral medicine and periodontology outpatient clinic, faculty of dentistry, kafrelsheikh University Kafr Ash Shaykh Kafrelsheikh 214312 Egypt NCT06401785 HoHo Biotech To Evaluate the Efficacy of Oral Molecular Hydrogen Supplement in Patients With Chronic Diseases May 11, 2024 Chronic Disease Chronic Inflammation Hydrogen supplement Oral hydrogen capsules Hydrogen capsules 60 Tri-Service General Hospital Taoyuan Armed Forces General Hospital Taipei Taoyuan Taiwan Taiwan NCT06401772 Huashan Hospital The Effectiveness and Safety of Body Posture in Preventing Postoperative Recurrence for Chronic Subdural Hematoma May 2024 Chronic Subdural Hematoma Recurrence Chronic Subdural Hematoma body posture intracranial pressure body posture 821 Department of Neurosurgery, Huashan Hospital, Fudan University Shanghai Shanghai 200000 China NCT06401759 Firat University Use of Podcasts in the Education of Hypertension Patients August 1, 2024 Hypertension Podcast Podcast 92 Fırat university Elazığ Center 25240 Turkey NCT06401746 University of Western Sydney Body Surface Gastric Mapping in Patients on Semaglutide May 1, 2024 Semaglutide-Induced Gastric Motility Gastroparesis Semaglutide GLP-1 Receptor Agonist Gastric Motility Body Surface Gastric Mapping Gastric Alimetry 15 Western Sydney University Campbelltown New South Wales 2560 Australia NCT06401733 National University of Singapore Intensive Aerobic and Resistance Exercise Program (IAREP) May 11, 2024 Type 2 Diabetes Mellitus Cognitive Impairment Non-insulin-dependent Diabetes Mellitus Cognitive Dysfunction T2DM circuit-based exercise neurology dementia obesity rehabilitation Intensive Aerobic and Resistance Exercise Program (IAREP) 80 NCT06401720 Karolinska Institutet Age Related Differences in Respiratory Immune Responses in Influenza Virus Infection January 1, 2024 Influenza A Infection Influenza B Virus Infection SARS CoV 2 Infection RSV Infection Influenza A virus (IAV) Influenza B virus (IBV) SARS CoV 2 respiratory syncytial virus (RSV) immunology age-related differences 800 Familjeläkarna Haga Närakut Karolinska Universitetssjukhuset Sabbatsbergs sjukhus Södertälje Sjukhus Stockholm Stockholm Stockholm Stockholm Södertälje Sweden Sweden Sweden Sweden Sweden NCT06401707 University of California, San Francisco PeRampanel fOr Status ePilEpticus pRophylaxis Post-cardiac Arrest May 20, 2024 Heart Arrest, Seizure, Status Epilepticus heart arrest, seizure, status epilepticus Perampanel 52 Zuckerberg San Francisco General Hospital San Francisco California 94110 United States NCT06401694 University of Connecticut Evaluating an Enhanced Home-delivered Meal Program on Older Adults' Health and Well-being May 20, 2024 Diet, Healthy Food Insecurity Loneliness Quality of Life Home-delivered meals Wellness check and socialization visit Community Health Worker calls Supplemental grocery bag 1640 NCT06401681 Old Dominion University Cross-Education for Chronic Ankle Instability May 8, 2019 Balance Training Group Control Group Balance training 30 Old Dominion University Athletic Training Laboratory Norfolk Virginia 20529 United States NCT06401668 Yale University Impact of a Community Health Worker Strategy on Produce Prescription Program Uptake Among People With Diabetes June 2024 Diabetes Type 2 Community health worker (CHW) strategy PRx Program 116 Hartford HealthCare/ St. Vincent Medical Center Hartford Connecticut 06102 United States NCT06401655 University of Manitoba Financial Coaching for Adults Living With Acquired Brain Injury February 21, 2024 Brain Injuries Stroke Financial capability Financial management Financial self-efficacy Goal attainment Strategy Training Financial Coaching for People living with Acquired Brain Injury (FC-ABI) 5 University of Manitoba Winnipeg Manitoba R3E 0T6 Canada NCT06401642 Mayo Clinic Effectiveness and Tolerability of Zavegepant for Acute Migraine Treatment Among Those Using CGRP Targeting Preventive Medications May 2024 Migraine Zavegepant 200 Mayo Clinic in Arizona Scottsdale Arizona 85259 United States NCT06401629 Qatar University Outcomes After Unified Versus Standard GDM Diagnosis January 1, 2025 Gestational Diabetes Diagnosis Pregnancy Gestational Diabetes Mellitus IADPSG NPRP Obesity Dysglycemia High-risk Pregnancy NPRP criteria IADPSG criteria 2650 NCT06401616 Odense University Hospital Can Patients With Atrial Fibrillation Safely Discontinue Anticoagulant Therapy After Cardiac Surgery? (ATLAAC) February 29, 2024 Atrial Fibrillation Left Atrial Appendage Absent Anticoagulant Adverse Reaction Atrial fibrillation Anticoagulant treatment Surgical left atrial appendage closure surgical left atrial appendage occlusion OAC will be discontinued for the duration ofthe trial 1220 Rigshospitalet Gentofte Hospital Regionshospital Gødstrup Århus Universitetshospital Aalborg university hospital Odense University Hospital Copenhagen Gentofte Herning Århus Aalborg Odense Region Hovedstaden Region Hovedstaden Region Midtjylland Region Midt Region Nordjylland Region Syddanmark Denmark Denmark Denmark Denmark Denmark Denmark NCT06401603 M.D. Anderson Cancer Center A Phase I Study of Decitabine, Lisaftoclax, and Olverembatinib in Patients With Advanced Chronic Myeloid Leukemia and Philadelphia Chromosome-Positive Acute Myeloid Leukemia October 31, 2024 Advanced Chronic Myeloid Leukemia Philadelphia Chromosome-Positive Acute Myeloid Leukemia Decitabine Listaftoclax Olverembatinib 30 MD Anderson Cancer Center Houston Texas 77030 United States NCT06401590 Aga Khan University Sensitivity and Predictive Value of Frozen Section of Sentinel Lymph Node Biopsy in Post Neoadjuvant Setting March 15, 2022 Lymph Node Metastasis Breast Cancer FROZEN SENTINEL LYMPH NODE BIOPSY 286 Aga Khan University Karachi Sindh 6300 Pakistan NCT06401577 Milton S. Hershey Medical Center Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics July 1, 2024 Acute Pancreatitis Diabetes Continuous Glucose Monitoring Dexcom Continuous Glucose Monitor (CGM) 800 University of Southern California Cedars-Sinai Medical Center Stanford University University of Florida AdventHealth Northwestern University University of Illinois at Chicago Indiana University Johns Hopkins University University of Minnesota Ohio State University University of Pittsburgh Benaroya Research Institute Los Angeles Los Angeles Stanford Gainesville Orlando Chicago Chicago Indianapolis Baltimore Minneapolis Columbus Pittsburgh Seattle California California California Florida Florida Illinois Illinois Indiana Maryland Minnesota Ohio Pennsylvania Washington 90033 90048 94305 32610-0214 32804 60611 60612 46202 21205 55454 43210 15213 98101 United States United States United States United States United States United States United States United States United States United States United States United States United States NCT06401564 Stony Brook University Virtual Reality Based Rehabilitation After Ischemic Stroke April 17, 2023 Ischemic Stroke virtual reality stroke rehabilitation quality of life upper extremity Virtual Reality Therapy 15 Stony Brook University Hospital Stony Brook New York 11794-8121 United States NCT06401551 Alcon Research Clareon PanOptix Pro vs. Clareon PanOptix - Study B June 2024 Aphakia Presbyopia Cataract IOL CPO Pro IOL CPO IOL Cataract Surgery 79 Wolstan & Goldberg Eye Associates Moyes Eye Center Vision for Life The Eye Institute of Utah Torrance Kansas City Nashville Salt Lake City California Missouri Tennessee Utah 90505 64154 37205 84107 United States United States United States United States NCT06401538 Bright Minds Biosciences Pty Ltd BMB-101 in Epilepsy With Eyelid Myoclonia (EEM) July 15, 2024 Jeavons Syndrome BMB-101 20 Alfred Health Melbourne Victoria 3004 Australia NCT06401525 [Redacted] [Trial of device that is not approved or cleared by the U.S. FDA] NCT06401512 Western Norway University of Applied Sciences Digital Follow-up Program for People With Chronic Obstructive Pulmonary Disease in Primary Healthcare May 2, 2024 COPD Chronic Obstructive Pulmonary Disease COPD Guided self-determination Primary healthcare Randomized controlled trial Web-based follow-up Guided self-determination (GSD) follow-up approach by primary care nurses. 80 Western Norway University of Applied Sciences Bergen 5063 Norway NCT06401499 Watim Medical & Dental College The Effect of Pregabalin and Etoricoxib on Pain Alone Versus in Combination June 1, 2024 Back Pain Lower Back Chronic etoricoxib 60mg 140 NCT06401486 Hospital Clinico Universitario de Santiago DOuble-Lumen Intubation With VIdeolaryngoscopy June 1, 2024 Intubation Complication Intubation; Difficult or Failed Anesthesia Videolaryngoscopy videolaryngoscopy tracheal intubation Videolaryngoscope Macintosh laryngoscope 916 Complexo Hospitalario Universitario de A Coruña Complexo Hospitalario Universitario de Santiago de Compostela Hospital Universitario La Fe de Valencia Complexo Hospitalario Universitario Vigo A Coruña Santiago de Compostela Valencia Vigo Spain Spain Spain Spain NCT06401473 Grand Canyon University Using the Gate Control Theory of Pain to Decrease Pain During Trigger Finger Corticosteroid Injections September 11, 2023 Trigger Finger Pain Gate Control Theory of Pain Injection Ipsilateral Scratch Task Motor Distraction Task 105 OrthoArizona Gilbert Arizona 85297 United States NCT06401460 Gansu University of Chinese Medicine Yannianjiuzhuan Method and Reverse Breathing Training to Improve Constipation in Elderly Patients With Coronary Heart Disease November 1, 2021 Constipation Coronary Heart Disease Yannianjiuzhuan method combined with reverse breathing training 67 Chengguanqu Lanzhou Gansu 730000 China NCT06401447 Fudan University TPF Concurrent Chemo-radiotherapy Plus Immunotherapy for Local Advanced Esophageal Squamous Cell Carcinoma December 1, 2023 Esophageal Squamous Cell Carcinoma Radiotherapy 50 Fudan University Shanghai Cancer Center Shanghai China NCT06401434 Freundeskreis Für Internationale Tuberkulosehilfe e.V Evaluation of CAD-based Triage for CXR Interpretation During TB Screening June 2024 Tuberculosis Tuberculosis (TB) AI-CAD software Active case finding (ACF) On-site radiologist CAD-based triage (with INSIGHT CXR software) 24000 Pham Ngoc Thach Hospital Long An Lung Hospital Pham Huu Chi Lung Hospital, BR-VT Ho Chi Minh City Long An Vung Tau Vietnam Vietnam Vietnam NCT06401421 Exact Sciences Corporation EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD) May 2024 Breast Cancer Breast Cancer ctDNA ctDNA MRD test 1800 NCT06401408 TC Erciyes University Effect of Virtual Reality Headsets on Fear Anxiety and Physiological Parameter in Skin Prick Test June 20, 2024 Allergy allergy 32 Erciyes University Health Application and Research Center Fevzi Mercan-Mustafa Eraslan Children's Hospital Kayseri Melikgazi 38050 Turkey NCT06401395 DIAMPARK Clinical Evaluation of A neW Management Strategy for Patients With pArKinson's disEase usiNg an Innovative telemonitorING (AWAKENING) July 1, 2024 Parkinson Disease Parkinson disease Telemonitoring Symptom management Quality of life DIGIPARK MONITOR 300 CHU Angers CH Flayriat CHU Caen Clinique du Plateau CH Emile Roux Clinique Beau Soleil CHU Nice CH de Troyes Hopital jean Bernard Médipole Hôpital Mutuliste Angers Bourg-en-Bresse Caen Clamart Le Puy-en-Velay Montpellier Nice Troyes Valenciennes Villeurbanne 69100 France France France France France France France France France France NCT06401382 Damascus University Oral Health-Related Quality of Life Between Two Different Types of Orthodontic Appliances June 2, 2022 Crowding of Anterior Mandibular Teeth A modified aligner appliance with NiTi springs Conventional fixed appliances 36 Department of Orthodontics, University of Damascus Dental School Damascus Syrian Arab Republic NCT06401369 Damascus University Comparing Labial and Lingual Orthodontic Appliances on Root Resorption and Bone Height March 10, 2022 Crowding of Anterior Maxillary Teeth Crowding of Anterior Mandibular Teeth Lingual brackets Buccal brackets 40 Department of Orthodontics, Faculty of Dentistry, University of Damsacus Damascus DM20 HAJ72 Syrian Arab Republic NCT06401356 Constellation Pharmaceuticals An Extension Study for Patients Previously Enrolled in Studies With Pelabresib June 1, 2024 Hematologic Malignancy Solid Tumor Advanced Malignancies Pelabresib 50 NCT06401343 China National Center for Cardiovascular Diseases Use of SGLT2i in noHCM With HFpEF August 1, 2022 Hypertrophic Cardiomyopathy Heart Failure With Preserved Ejection Fraction Empagliflozin 10 MG 94 Fuwai Hospital, National Centre for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing Beijing 100037 China NCT06401330 Children's Oncology Group A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT) June 12, 2024 Stage I Kidney Wilms Tumor Stage II Kidney Wilms Tumor Stage III Kidney Wilms Tumor Stage IV Kidney Wilms Tumor Bone Scan Carboplatin Computed Tomography Cyclophosphamide Dactinomycin Doxorubicin Etoposide Irinotecan Magnetic Resonance Imaging Nephrectomy Patient Observation Positron Emission Tomography Ultrasound Imaging Vincristine X-Ray Imaging 1656 NCT06401317 Université du Québec à Trois-Rivières Corticosteroid Against Saline Injections for Thumb Osteoarthritis (CASITOA) September 1, 2024 Thumb Osteoarthritis Osteoarthritis Hand Injections Corticosteroids Feasibility Blinding Randomized controlled trial Saline Hypertonic Solution Triamcinolone Acetonide 40 NCT06401304 Uppsala University Oncologic, Cosmetic and Patient Reported Outcomes in Value-Based Breast Surgery (OnCoPRO Value) January 1, 2020 Breast Cancer Breast Carcinoma in Situ Breast Cancer Invasive Breast Asymmetry Oncoplastic breast conservation Breast Conserving Surgery Patient reported outcomes Shared decision making 1200 Westmead Breast Cancer Institute Uppsala University Hospital Royal Marsden Hospital Sydney Uppsala London 75185 Australia Sweden United Kingdom NCT06401291 Catharina Ziekenhuis Eindhoven Transcutaneous Electrical Nerve Stimulation in Patients With Angina and Non-Obstructive Coronary Arteries March 13, 2024 Microvascular Angina Vasospastic Angina Transcutaneous Electrical Nerve Stimulation 20 Catharina Hospital Eindhoven Noord Brabant 5623EJ Netherlands NCT06401278 Cairo University Trans Cutaneous Electrical Acupoint Stimulation Versus TENS On Blood Pressure In Primary Hypertension Patients May 5, 2024 Hypertension Quality of Life Transcutaneous electrical acupoint stimulation Transcutaneous electrical nerve stimulation (group b): 60 Faculty of physical therapy- Cairo Uni. Giza 12611 Egypt NCT06401265 Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation Recalling the Treatment and Prognosis of Upper Tract Urothelial Cancer (UTUC) January 1, 2018 Uterine Cancer 8000 Tzu Chi hospital Taipei Taiwan NCT06401252 Jordan University of Science and Technology Mindfulness for Nurses' Psychological Health January 30, 2022 Psychological Well-Being Nurse's Role Mindfulness-based intervention, Stress, Depression, Anxiety, Nurses, COVID-19. Mindfulness-based intervention 102 Jordan University of Science and Technology Irbid None Selected 22110 Jordan NCT06401239 Johns Hopkins University Investigating Dyadic Expectations About ARF Survivorship (IDEAS) July 2024 Acute Respiratory Failure Caregiving Stress Mental Health Issue ARF survivor Caregiver ICU recovery Dyadic coping Dyadic self-efficacy Dyadic expectations about the ARF survivor's perceived health 6 months after hospital discharge Self-efficacy Concordant expectations/shared appraisal of ARF survivor's health 6 months after hospital discharge 235 Johns Hopkins Hospital Baltimore Maryland 21205 United States NCT06401226 Bezmialem Vakif University Pain and Physical Fitness in Primary Dysmenorrhea June 1, 2023 Primary Dysmenorrhea 48 Bezmialem Vakif University Istanbul Turkey NCT06401213 Mediar Therapeutics A First-in-Human Safety Trial of MTX-463 April 15, 2024 Healthy HEALTHY VOLUNTEER SAD MAD MTX-463-I101 MTX-463 WISP-1 ADULT MTX-463 Placebo 56 ICON Salt Lake City Utah 84124 United States NCT06401200 Minia University Radiographic and Clinical Evaluation In Bar November 15, 2022 Dental SLM Milled Bar overdenture bar retained implant overdenture 20 Minia University Minya Minia 61511 Egypt NCT06401187 Minia University Patient Satisfaction and Maximum Biting Force in Co-Cr Bar Implant Overdenture November 10, 2022 Dental implants, Milled 3D printed Patient satisfaction Bar overdenture 30 Minia University Minya Minia 61511 Egypt NCT06401174 Medstar Health Research Institute Patient Navigation for Colorectal Cancer Screening June 1, 2024 Colorectal Cancer Screening disparities Patient navigation Delivery of patient navigation 1800 Internal Medicine Wisconsin Avenue Family Medicine Spring Valley Primary Care Lafayette Family Medicine Fort Lincoln Honeygo MedStar Adult Medicine at Union Memorial Harbor Hospital Primary Care Federal Hill Franklin Square Primary Care at Franklin Square Charlotte Hall Internal Medicine Clinton Family Medicine Internal Medicine Hyattsville Family Medicine Olney Prof Park Washington Washington Washington Washington Baltimore Baltimore Baltimore Baltimore Baltimore Charlotte Hall Clinton Gaithersburg Hyattsville Olney Olney District of Columbia District of Columbia District of Columbia District of Columbia Maryland Maryland Maryland Maryland Maryland Maryland Maryland Maryland Maryland Maryland Maryland 20007 20016 20036 20722 21128 21218 21230 21237 21237 20622 20735 20878 20782 20832 20832 United States United States United States United States United States United States United States United States United States United States United States United States United States United States United States NCT06401161 Longgang District People's Hospital of Shenzhen Study on the Effect of 3T Pu'er Tea in Regulating Glucose and Lipid Metabolism November 1, 2022 Overweight Obesity Pu' er Tea glucose and lipid metabolism intestinalflora 3T Pu'er tea 94 Longgang District People's Hospital of Shenzhen Shenzhen Guangdong 518172 China NCT06401148 Liverpool John Moores University Exercise-based Cardiac Rehabilitation for Atrial Fibrillation May 2024 Atrial Fibrillation Cardiac rehab intervention group 80 NCT06401135 Mustafa Kemal University Effects of Different Inspiratory Muscle Training Protocols in Patients With Chronic Kidney Disease July 28, 2021 Chronic Kidney Diseases Inspiratory Muscle Training Exercise Capacity Chronic kidney disease Inspiratory muscle training Inspiratory muscle training 47 Hatay Mustafa Kemal University Hatay 31001 Turkey NCT06401122 Assiut University Comparison of Dyslipidemia Among Diabetics Versus Non Diabetics in Haemodialysis Patients June 1, 2024 Dyslipidemias haemodialysis diabetes mellitus haemodialysis 100 NCT06401109 AquaPass Medical Ltd. Naturally Controlled Decongestion Using Renal Independent System in ADHF Patients, a European Registry February 2025 Chronic Heart Failure Fluid Overload Acute Decompensated Heart Failure Edema AquaPass 30 NCT06401096 Ankara City Hospital Bilkent Evaluation of the Effects of Preoperative Breathing Exercises on Preoxygenation Period May 1, 2024 Pre-operative Exercise Preoperative respiratory exercises 186 Ankara Bilkent City Hospital Ankara Çankaya 06530 Turkey NCT06401083 Semmelweis University The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate December 21, 2023 Apnea of Prematurity Premature Birth Respiratory Failure prematurity caffeine methylxanthine apnea of prematurity extubation failure Caffeine citrate 226 Pediatric Center, Semmelweis University Department of Obstetrics and Gynecology, Semmelweis University Budapest Budapest 1083 1088 Hungary Hungary NCT06401070 Indonesia University Effect of Auricular Press Needle on Improvement of Patient Health Questionnaire-9 (PHQ-9) and Heart Rate Variability (HRV) Patient With Depression Symptoms in Chronic Pain May 1, 2024 Depression Symptoms Chronic Pain acupuncture auricular acupuncture ear acupuncture depression symptoms chronic pain press needle Plesterin Press needle acupuncture 60