ClinicalTrials.gov
History of Changes for Study: NCT02954874
Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer
Latest version (submitted May 18, 2024) on ClinicalTrials.gov
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Study Record Versions
Version A B Submitted Date Changes
1 November 3, 2016 None (earliest Version on record)
2 November 24, 2016 Contacts/Locations and Study Status
3 November 28, 2016 Recruitment Status, Study Status and Contacts/Locations
4 December 15, 2016 Contacts/Locations and Study Status
5 December 19, 2016 Contacts/Locations and Study Status
6 December 20, 2016 Contacts/Locations and Study Status
7 December 28, 2016 Contacts/Locations and Study Status
8 December 30, 2016 Contacts/Locations and Study Status
9 January 2, 2017 Contacts/Locations and Study Status
10 January 5, 2017 Contacts/Locations and Study Status
11 January 9, 2017 Contacts/Locations and Study Status
12 January 11, 2017 Contacts/Locations and Study Status
13 January 12, 2017 Contacts/Locations and Study Status
14 January 13, 2017 Contacts/Locations and Study Status
15 January 16, 2017 Contacts/Locations and Study Status
16 January 18, 2017 Contacts/Locations and Study Status
17 January 19, 2017 Contacts/Locations and Study Status
18 January 20, 2017 Contacts/Locations and Study Status
19 January 23, 2017 Contacts/Locations and Study Status
20 January 24, 2017 Study Status
21 January 30, 2017 Contacts/Locations and Study Status
22 January 31, 2017 Study Status
23 February 3, 2017 Contacts/Locations and Study Status
24 February 6, 2017 Contacts/Locations and Study Status
25 February 7, 2017 Study Status
26 February 8, 2017 Study Status
27 February 9, 2017 Study Status
28 February 13, 2017 Study Status
29 February 14, 2017 Contacts/Locations and Study Status
30 February 15, 2017 Contacts/Locations and Study Status
31 February 16, 2017 Contacts/Locations and Study Status
32 February 20, 2017 Contacts/Locations and Study Status
33 February 21, 2017 Study Status
34 February 23, 2017 Contacts/Locations and Study Status
35 February 27, 2017 Study Status
36 February 28, 2017 Contacts/Locations and Study Status
37 March 1, 2017 Contacts/Locations and Study Status
38 March 2, 2017 Study Status
39 March 3, 2017 Study Status
40 March 6, 2017 Contacts/Locations and Study Status
41 March 8, 2017 Contacts/Locations and Study Status
42 March 9, 2017 Contacts/Locations and Study Status
43 March 10, 2017 Contacts/Locations and Study Status
44 March 13, 2017 Contacts/Locations and Study Status
45 March 17, 2017 Contacts/Locations and Study Status
46 March 21, 2017 Study Status
47 March 22, 2017 Contacts/Locations and Study Status
48 March 27, 2017 Contacts/Locations and Study Status
49 March 30, 2017 Contacts/Locations and Study Status
50 March 31, 2017 Contacts/Locations and Study Status
51 April 3, 2017 Contacts/Locations and Study Status
52 April 4, 2017 Contacts/Locations and Study Status
53 April 6, 2017 Contacts/Locations and Study Status
54 April 7, 2017 Contacts/Locations and Study Status
55 April 11, 2017 Study Status
56 April 12, 2017 Contacts/Locations and Study Status
57 April 13, 2017 Contacts/Locations and Study Status
58 April 14, 2017 Study Status
59 April 17, 2017 Contacts/Locations and Study Status
60 April 19, 2017 Contacts/Locations and Study Status
61 April 20, 2017 Contacts/Locations and Study Status
62 April 21, 2017 Contacts/Locations and Study Status
63 April 24, 2017 Contacts/Locations and Study Status
64 April 25, 2017 Study Status
65 April 26, 2017 Study Status
66 April 27, 2017 Study Status
67 May 1, 2017 Contacts/Locations and Study Status
68 May 3, 2017 Contacts/Locations and Study Status
69 May 5, 2017 Contacts/Locations and Study Status
70 May 10, 2017 Study Status
71 May 11, 2017 Study Status and Contacts/Locations
72 May 12, 2017 Contacts/Locations and Study Status
73 May 16, 2017 Study Status
74 May 17, 2017 Contacts/Locations and Study Status
75 May 19, 2017 Contacts/Locations and Study Status
76 May 23, 2017 Study Status and Contacts/Locations
77 May 24, 2017 Contacts/Locations and Study Status
78 May 26, 2017 Contacts/Locations and Study Status
79 May 29, 2017 Contacts/Locations and Study Status
80 May 31, 2017 Study Status
81 June 2, 2017 Study Status
82 June 13, 2017 Outcome Measures, Study Status, Contacts/Locations, Eligibility and Study Identification
83 June 14, 2017 Study Status
84 June 15, 2017 Contacts/Locations and Study Status
85 June 16, 2017 Contacts/Locations and Study Status
86 June 19, 2017 Contacts/Locations and Study Status
87 June 20, 2017 Contacts/Locations and Study Status
88 June 21, 2017 Study Status
89 June 22, 2017 Contacts/Locations and Study Status
90 June 23, 2017 Contacts/Locations and Study Status
91 June 26, 2017 Arms and Interventions and Study Status
92 June 27, 2017 Study Status
93 June 28, 2017 Contacts/Locations and Study Status
94 June 29, 2017 Contacts/Locations and Study Status
95 June 30, 2017 Study Status
96 July 3, 2017 Contacts/Locations and Study Status
97 July 5, 2017 Contacts/Locations and Study Status
98 July 10, 2017 Contacts/Locations, Arms and Interventions and Study Status
99 July 11, 2017 Study Status
100 July 13, 2017 Contacts/Locations and Study Status
101 July 14, 2017 Contacts/Locations and Study Status
102 July 17, 2017 Contacts/Locations and Study Status
103 July 19, 2017 Study Status
104 July 20, 2017 Study Status
105 July 24, 2017 Study Status
106 July 25, 2017 Study Status
107 July 26, 2017 Study Status
108 July 27, 2017 Contacts/Locations and Study Status
109 July 28, 2017 Contacts/Locations and Study Status
110 July 31, 2017 Contacts/Locations and Study Status
111 August 1, 2017 Contacts/Locations and Study Status
112 August 2, 2017 Contacts/Locations and Study Status
113 August 3, 2017 Contacts/Locations and Study Status
114 August 4, 2017 Contacts/Locations and Study Status
115 August 7, 2017 Study Status
116 August 8, 2017 Study Status
117 August 9, 2017 Study Status
118 August 10, 2017 Contacts/Locations and Study Status
119 August 11, 2017 Contacts/Locations and Study Status
120 August 14, 2017 Contacts/Locations, Arms and Interventions and Study Status
121 August 15, 2017 Study Status
122 August 17, 2017 Study Status
123 August 18, 2017 Contacts/Locations and Study Status
124 August 21, 2017 Contacts/Locations and Study Status
125 August 24, 2017 Contacts/Locations and Study Status
126 August 25, 2017 Contacts/Locations and Study Status
127 August 28, 2017 Contacts/Locations and Study Status
128 August 29, 2017 Study Status
129 August 30, 2017 Contacts/Locations and Study Status
130 September 4, 2017 Arms and Interventions, Contacts/Locations and Study Status
131 September 6, 2017 Study Status
132 September 7, 2017 Study Status
133 September 8, 2017 Study Status
134 September 12, 2017 Study Status
135 September 14, 2017 Contacts/Locations and Study Status
136 September 18, 2017 Contacts/Locations and Study Status
137 September 19, 2017 Study Status
138 September 21, 2017 Contacts/Locations and Study Status
139 September 25, 2017 Contacts/Locations and Study Status
140 September 26, 2017 Contacts/Locations and Study Status
141 September 28, 2017 Contacts/Locations and Study Status
142 October 2, 2017 Contacts/Locations and Study Status
143 October 3, 2017 Contacts/Locations and Study Status
144 October 4, 2017 Contacts/Locations and Study Status
145 October 5, 2017 Contacts/Locations and Study Status
146 October 6, 2017 Contacts/Locations and Study Status
147 October 9, 2017 Contacts/Locations and Study Status
148 October 10, 2017 Study Status
149 October 11, 2017 Contacts/Locations and Study Status
150 October 12, 2017 Study Status
151 October 13, 2017 Contacts/Locations and Study Status
152 October 16, 2017 Conditions and Study Status
153 October 17, 2017 Study Status
154 October 18, 2017 Contacts/Locations and Study Status
155 October 19, 2017 Contacts/Locations and Study Status
156 October 20, 2017 Contacts/Locations and Study Status
157 October 23, 2017 Contacts/Locations and Study Status
158 October 24, 2017 Study Status
159 October 25, 2017 Study Status
160 October 26, 2017 Study Status and Study Identification
161 October 27, 2017 Contacts/Locations and Study Status
162 October 30, 2017 Contacts/Locations and Study Status
163 October 31, 2017 Study Status
164 November 1, 2017 Contacts/Locations and Study Status
165 November 3, 2017 Contacts/Locations and Study Status
166 November 6, 2017 Study Status and Contacts/Locations
167 November 7, 2017 Study Status
168 November 8, 2017 Contacts/Locations and Study Status
169 November 9, 2017 Contacts/Locations and Study Status
170 November 13, 2017 Contacts/Locations and Study Status
171 November 15, 2017 Contacts/Locations and Study Status
172 November 16, 2017 Contacts/Locations and Study Status
173 November 17, 2017 Contacts/Locations and Study Status
174 November 20, 2017 Contacts/Locations and Study Status
175 November 21, 2017 Study Status
176 November 22, 2017 Study Status
177 November 24, 2017 Study Status
178 November 27, 2017 Contacts/Locations and Study Status
179 November 28, 2017 Contacts/Locations and Study Status
180 November 30, 2017 Contacts/Locations and Study Status
181 December 1, 2017 Study Status
182 December 4, 2017 Study Status
183 December 5, 2017 Study Status
184 December 7, 2017 Study Status
185 December 11, 2017 Contacts/Locations, Arms and Interventions and Study Status
186 December 12, 2017 Study Status
187 December 13, 2017 Study Status
188 December 14, 2017 Study Status
189 December 15, 2017 Contacts/Locations and Study Status
190 December 18, 2017 Contacts/Locations and Study Status
191 December 19, 2017 Study Status
192 December 20, 2017 Study Status
193 December 21, 2017 Study Status
194 December 22, 2017 Study Status
195 December 26, 2017 Contacts/Locations and Study Status
196 December 27, 2017 Study Status
197 December 28, 2017 Contacts/Locations and Study Status
198 December 29, 2017 Study Status
199 January 2, 2018 Contacts/Locations and Study Status
200 January 3, 2018 Study Status
201 January 4, 2018 Contacts/Locations and Study Status
202 January 5, 2018 Study Status
203 January 8, 2018 Contacts/Locations and Study Status
204 January 9, 2018 Study Status
205 January 10, 2018 Study Status
206 January 23, 2018 Contacts/Locations, Study Status and Eligibility
207 January 24, 2018 Contacts/Locations and Study Status
208 January 25, 2018 Contacts/Locations and Study Status
209 January 26, 2018 Contacts/Locations and Study Status
210 January 29, 2018 Contacts/Locations and Study Status
211 January 31, 2018 Study Status
212 February 1, 2018 Contacts/Locations and Study Status
213 February 2, 2018 Study Status
214 February 5, 2018 Contacts/Locations and Study Status
215 February 6, 2018 Contacts/Locations and Study Status
216 February 7, 2018 Study Status
217 February 8, 2018 Contacts/Locations and Study Status
218 February 9, 2018 Contacts/Locations and Study Status
219 February 12, 2018 Contacts/Locations and Study Status
220 February 13, 2018 Study Status
221 February 14, 2018 Study Status
222 February 15, 2018 Outcome Measures, Contacts/Locations and Study Status
223 February 16, 2018 Study Status
224 February 19, 2018 Contacts/Locations and Study Status
225 February 20, 2018 Study Status
226 February 22, 2018 Contacts/Locations and Study Status
227 February 23, 2018 Contacts/Locations and Study Status
228 February 26, 2018 Contacts/Locations and Study Status
229 February 27, 2018 Contacts/Locations and Study Status
230 February 28, 2018 Contacts/Locations and Study Status
231 March 1, 2018 Contacts/Locations and Study Status
232 March 2, 2018 Study Status
233 March 5, 2018 Contacts/Locations and Study Status
234 March 7, 2018 Contacts/Locations and Study Status
235 March 8, 2018 Contacts/Locations and Study Status
236 March 9, 2018 Contacts/Locations and Study Status
237 March 12, 2018 Contacts/Locations and Study Status
238 March 13, 2018 Study Status
239 March 14, 2018 Contacts/Locations and Study Status
240 March 15, 2018 Study Status
241 March 16, 2018 Contacts/Locations and Study Status
242 March 19, 2018 Contacts/Locations and Study Status
243 March 20, 2018 Contacts/Locations and Study Status
244 March 21, 2018 Contacts/Locations and Study Status
245 March 22, 2018 Contacts/Locations and Study Status
246 March 26, 2018 Contacts/Locations and Study Status
247 March 29, 2018 Contacts/Locations and Study Status
248 April 2, 2018 Contacts/Locations and Study Status
249 April 3, 2018 Contacts/Locations and Study Status
250 April 4, 2018 Contacts/Locations and Study Status
251 April 9, 2018 Contacts/Locations and Study Status
252 April 12, 2018 Contacts/Locations and Study Status
253 April 16, 2018 Contacts/Locations and Study Status
254 April 17, 2018 Contacts/Locations and Study Status
255 April 18, 2018 Contacts/Locations and Study Status
256 April 20, 2018 Contacts/Locations and Study Status
257 April 23, 2018 Contacts/Locations and Study Status
258 April 25, 2018 Contacts/Locations and Study Status
259 April 26, 2018 Contacts/Locations and Study Status
260 April 27, 2018 Contacts/Locations and Study Status
261 April 30, 2018 Contacts/Locations and Study Status
262 May 2, 2018 Contacts/Locations and Study Status
263 May 3, 2018 Contacts/Locations and Study Status
264 May 7, 2018 Contacts/Locations and Study Status
265 May 11, 2018 Contacts/Locations and Study Status
266 May 14, 2018 Contacts/Locations and Study Status
267 May 16, 2018 Contacts/Locations and Study Status
268 May 18, 2018 Contacts/Locations and Study Status
269 May 21, 2018 Contacts/Locations and Study Status
270 May 22, 2018 Contacts/Locations and Study Status
271 May 23, 2018 Contacts/Locations and Study Status
272 May 24, 2018 Contacts/Locations and Study Status
273 June 11, 2018 Contacts/Locations, Arms and Interventions, Study Description and Study Status
274 June 14, 2018 Contacts/Locations and Study Status
275 June 18, 2018 Contacts/Locations and Study Status
276 June 21, 2018 Contacts/Locations and Study Status
277 June 22, 2018 Study Status
278 June 25, 2018 Contacts/Locations and Study Status
279 June 27, 2018 Contacts/Locations and Study Status
280 June 28, 2018 Contacts/Locations and Study Status
281 June 29, 2018 Contacts/Locations and Study Status
282 July 2, 2018 Contacts/Locations and Study Status
283 July 6, 2018 Contacts/Locations and Study Status
284 July 9, 2018 Contacts/Locations and Study Status
285 July 11, 2018 Contacts/Locations and Study Status
286 July 13, 2018 Contacts/Locations and Study Status
287 July 16, 2018 Contacts/Locations and Study Status
288 July 18, 2018 Contacts/Locations and Study Status
289 July 19, 2018 Contacts/Locations and Study Status
290 July 20, 2018 Contacts/Locations and Study Status
291 July 23, 2018 Contacts/Locations and Study Status
292 July 24, 2018 Contacts/Locations and Study Status
293 July 25, 2018 Contacts/Locations and Study Status
294 July 26, 2018 Contacts/Locations and Study Status
295 July 27, 2018 Contacts/Locations and Study Status
296 July 30, 2018 Contacts/Locations and Study Status
297 July 31, 2018 Contacts/Locations and Study Status
298 August 1, 2018 Contacts/Locations and Study Status
299 August 2, 2018 Contacts/Locations and Study Status
300 August 3, 2018 Contacts/Locations and Study Status
301 August 6, 2018 Contacts/Locations and Study Status
302 August 8, 2018 Contacts/Locations and Study Status
303 August 9, 2018 Contacts/Locations and Study Status
304 August 10, 2018 Contacts/Locations and Study Status
305 August 14, 2018 Contacts/Locations and Study Status
306 August 15, 2018 Contacts/Locations and Study Status
307 August 16, 2018 Contacts/Locations and Study Status
308 August 17, 2018 Contacts/Locations and Study Status
309 August 20, 2018 Contacts/Locations and Study Status
310 August 21, 2018 Contacts/Locations and Study Status
311 August 23, 2018 Contacts/Locations and Study Status
312 August 24, 2018 Contacts/Locations and Study Status
313 August 27, 2018 Contacts/Locations and Study Status
314 August 30, 2018 Contacts/Locations and Study Status
315 August 31, 2018 Contacts/Locations and Study Status
316 September 6, 2018 Contacts/Locations and Study Status
317 September 7, 2018 Contacts/Locations and Study Status
318 September 10, 2018 Contacts/Locations and Study Status
319 September 11, 2018 Contacts/Locations and Study Status
320 September 12, 2018 Contacts/Locations and Study Status
321 September 13, 2018 Contacts/Locations and Study Status
322 September 14, 2018 Contacts/Locations and Study Status
323 September 17, 2018 Contacts/Locations and Study Status
324 September 18, 2018 Contacts/Locations and Study Status
325 September 19, 2018 Contacts/Locations and Study Status
326 September 20, 2018 Contacts/Locations and Study Status
327 September 21, 2018 Contacts/Locations and Study Status
328 September 24, 2018 Contacts/Locations and Study Status
329 September 25, 2018 Contacts/Locations and Study Status
330 September 26, 2018 Contacts/Locations and Study Status
331 September 27, 2018 Contacts/Locations and Study Status
332 September 28, 2018 Contacts/Locations and Study Status
333 October 1, 2018 Contacts/Locations and Study Status
334 October 3, 2018 Contacts/Locations and Study Status
335 October 4, 2018 Contacts/Locations and Study Status
336 October 5, 2018 Contacts/Locations and Study Status
337 October 8, 2018 Contacts/Locations and Study Status
338 October 9, 2018 Contacts/Locations and Study Status
339 October 10, 2018 Contacts/Locations and Study Status
340 October 11, 2018 Contacts/Locations and Study Status
341 October 12, 2018 Contacts/Locations and Study Status
342 October 15, 2018 Contacts/Locations and Study Status
343 October 17, 2018 Contacts/Locations and Study Status
344 October 18, 2018 Contacts/Locations and Study Status
345 October 19, 2018 Contacts/Locations and Study Status
346 October 22, 2018 Contacts/Locations and Study Status
347 October 23, 2018 Contacts/Locations and Study Status
348 October 24, 2018 Contacts/Locations and Study Status
349 October 25, 2018 Contacts/Locations and Study Status
350 October 26, 2018 Contacts/Locations and Study Status
351 October 30, 2018 Contacts/Locations and Study Status
352 October 31, 2018 Contacts/Locations and Study Status
353 November 1, 2018 Contacts/Locations and Study Status
354 November 2, 2018 Contacts/Locations and Study Status
355 November 5, 2018 Contacts/Locations and Study Status
356 November 6, 2018 Contacts/Locations and Study Status
357 November 7, 2018 Contacts/Locations and Study Status
358 November 8, 2018 Contacts/Locations and Study Status
359 November 9, 2018 Contacts/Locations and Study Status
360 November 13, 2018 Contacts/Locations and Study Status
361 November 14, 2018 Contacts/Locations and Study Status
362 November 15, 2018 Contacts/Locations and Study Status
363 November 16, 2018 Contacts/Locations and Study Status
364 November 19, 2018 Contacts/Locations and Study Status
365 November 20, 2018 Contacts/Locations and Study Status
366 November 23, 2018 Contacts/Locations and Study Status
367 December 4, 2018 Contacts/Locations and Study Status
368 December 5, 2018 Contacts/Locations and Study Status
369 December 6, 2018 Contacts/Locations and Study Status
370 December 7, 2018 Contacts/Locations and Study Status
371 December 10, 2018 Contacts/Locations and Study Status
372 December 13, 2018 Contacts/Locations and Study Status
373 December 14, 2018 Contacts/Locations and Study Status
374 December 17, 2018 Contacts/Locations and Study Status
375 December 18, 2018 Contacts/Locations and Study Status
376 December 19, 2018 Contacts/Locations and Study Status
377 December 20, 2018 Contacts/Locations and Study Status
378 December 21, 2018 Contacts/Locations and Study Status
379 December 24, 2018 Contacts/Locations and Study Status
380 December 27, 2018 Contacts/Locations and Study Status
381 December 31, 2018 Contacts/Locations and Study Status
382 January 7, 2019 Contacts/Locations and Study Status
383 January 8, 2019 Contacts/Locations and Study Status
384 January 11, 2019 Contacts/Locations and Study Status
385 January 14, 2019 Contacts/Locations and Study Status
386 January 16, 2019 Contacts/Locations and Study Status
387 January 17, 2019 Contacts/Locations and Study Status
388 January 18, 2019 Contacts/Locations and Study Status
389 January 22, 2019 Contacts/Locations and Study Status
390 January 23, 2019 Contacts/Locations and Study Status
391 January 24, 2019 Contacts/Locations and Study Status
392 January 25, 2019 Contacts/Locations and Study Status
393 January 28, 2019 Contacts/Locations and Study Status
394 January 29, 2019 Contacts/Locations and Study Status
395 January 30, 2019 Contacts/Locations and Study Status
396 January 31, 2019 Contacts/Locations and Study Status
397 February 1, 2019 Contacts/Locations and Study Status
398 February 4, 2019 Contacts/Locations and Study Status
399 February 14, 2019 Contacts/Locations and Study Status
400 February 15, 2019 Contacts/Locations and Study Status
401 February 19, 2019 Contacts/Locations and Study Status
402 February 20, 2019 Contacts/Locations and Study Status
403 February 21, 2019 Contacts/Locations and Study Status
404 February 22, 2019 Contacts/Locations and Study Status
405 February 25, 2019 Contacts/Locations and Study Status
406 February 27, 2019 Contacts/Locations and Study Status
407 February 28, 2019 Contacts/Locations and Study Status
408 March 1, 2019 Contacts/Locations and Study Status
409 March 4, 2019 Contacts/Locations and Study Status
410 March 5, 2019 Contacts/Locations and Study Status
411 March 6, 2019 Contacts/Locations and Study Status
412 March 7, 2019 Contacts/Locations and Study Status
413 March 11, 2019 Contacts/Locations and Study Status
414 March 12, 2019 Contacts/Locations and Study Status
415 March 13, 2019 Contacts/Locations and Study Status
416 March 14, 2019 Contacts/Locations and Study Status
417 March 15, 2019 Contacts/Locations and Study Status
418 March 18, 2019 Contacts/Locations and Study Status
419 March 19, 2019 Contacts/Locations and Study Status
420 March 20, 2019 Contacts/Locations and Study Status
421 March 21, 2019 Contacts/Locations and Study Status
422 March 22, 2019 Contacts/Locations and Study Status
423 March 25, 2019 Contacts/Locations and Study Status
424 March 28, 2019 Contacts/Locations and Study Status
425 April 1, 2019 Contacts/Locations and Study Status
426 April 2, 2019 Contacts/Locations and Study Status
427 April 4, 2019 Contacts/Locations and Study Status
428 April 5, 2019 Contacts/Locations and Study Status
429 April 8, 2019 Contacts/Locations and Study Status
430 April 9, 2019 Contacts/Locations and Study Status
431 April 10, 2019 Contacts/Locations and Study Status
432 April 12, 2019 Contacts/Locations and Study Status
433 April 15, 2019 Contacts/Locations and Study Status
434 April 16, 2019 Contacts/Locations and Study Status
435 April 22, 2019 Contacts/Locations and Study Status
436 April 24, 2019 Contacts/Locations and Study Status
437 April 26, 2019 Contacts/Locations and Study Status
438 April 29, 2019 Contacts/Locations and Study Status
439 April 30, 2019 Contacts/Locations and Study Status
440 May 6, 2019 Contacts/Locations and Study Status
441 May 9, 2019 Contacts/Locations and Study Status
442 May 10, 2019 Contacts/Locations and Study Status
443 May 13, 2019 Contacts/Locations and Study Status
444 May 14, 2019 Contacts/Locations and Study Status
445 May 15, 2019 Contacts/Locations and Study Status
446 May 16, 2019 Contacts/Locations and Study Status
447 May 20, 2019 Contacts/Locations and Study Status
448 May 21, 2019 Contacts/Locations and Study Status
449 May 22, 2019 Contacts/Locations and Study Status
450 May 23, 2019 Contacts/Locations and Study Status
451 May 24, 2019 Contacts/Locations and Study Status
452 May 27, 2019 Contacts/Locations and Study Status
453 May 29, 2019 Contacts/Locations and Study Status
454 May 30, 2019 Contacts/Locations and Study Status
455 June 3, 2019 Contacts/Locations, Arms and Interventions and Study Status
456 June 5, 2019 Contacts/Locations and Study Status
457 June 6, 2019 Contacts/Locations and Study Status
458 June 7, 2019 Contacts/Locations and Study Status
459 June 10, 2019 Contacts/Locations, Arms and Interventions and Study Status
460 June 11, 2019 Contacts/Locations and Study Status
461 June 12, 2019 Contacts/Locations and Study Status
462 June 13, 2019 Contacts/Locations and Study Status
463 June 14, 2019 Contacts/Locations and Study Status
464 June 19, 2019 Contacts/Locations and Study Status
465 June 20, 2019 Contacts/Locations and Study Status
466 June 21, 2019 Contacts/Locations and Study Status
467 June 24, 2019 Contacts/Locations and Study Status
468 June 26, 2019 Contacts/Locations and Study Status
469 June 27, 2019 Contacts/Locations and Study Status
470 July 1, 2019 Contacts/Locations and Study Status
471 July 2, 2019 Contacts/Locations and Study Status
472 July 3, 2019 Contacts/Locations and Study Status
473 July 5, 2019 Contacts/Locations and Study Status
474 July 8, 2019 Contacts/Locations and Study Status
475 July 11, 2019 Contacts/Locations and Study Status
476 July 12, 2019 Contacts/Locations and Study Status
477 July 15, 2019 Contacts/Locations and Study Status
478 July 16, 2019 Contacts/Locations and Study Status
479 July 18, 2019 Contacts/Locations and Study Status
480 July 22, 2019 Contacts/Locations and Study Status
481 July 24, 2019 Contacts/Locations and Study Status
482 July 25, 2019 Contacts/Locations and Study Status
483 July 26, 2019 Contacts/Locations and Study Status
484 July 29, 2019 Contacts/Locations and Study Status
485 July 31, 2019 Contacts/Locations and Study Status
486 August 1, 2019 Contacts/Locations and Study Status
487 August 2, 2019 Contacts/Locations and Study Status
488 August 5, 2019 Contacts/Locations and Study Status
489 August 6, 2019 Contacts/Locations and Study Status
490 August 7, 2019 Contacts/Locations and Study Status
491 August 8, 2019 Contacts/Locations and Study Status
492 August 12, 2019 Contacts/Locations and Study Status
493 August 13, 2019 Contacts/Locations and Study Status
494 August 14, 2019 Contacts/Locations and Study Status
495 August 26, 2019 Outcome Measures, Contacts/Locations, Study Description, Eligibility, Arms and Interventions, Oversight, Study Status and Study Identification
496 August 27, 2019 Contacts/Locations and Study Status
497 August 29, 2019 Contacts/Locations and Study Status
498 August 30, 2019 Contacts/Locations and Study Status
499 September 2, 2019 Contacts/Locations and Study Status
500 September 4, 2019 Contacts/Locations and Study Status
501 September 5, 2019 Contacts/Locations and Study Status
502 September 6, 2019 Contacts/Locations and Study Status
503 September 9, 2019 Contacts/Locations and Study Status
504 September 11, 2019 Contacts/Locations and Study Status
505 September 12, 2019 Contacts/Locations and Study Status
506 September 16, 2019 Contacts/Locations and Study Status
507 September 18, 2019 Contacts/Locations and Study Status
508 September 19, 2019 Contacts/Locations and Study Status
509 September 20, 2019 Contacts/Locations and Study Status
510 September 23, 2019 Contacts/Locations and Study Status
511 September 24, 2019 Contacts/Locations and Study Status
512 September 25, 2019 Contacts/Locations and Study Status
513 September 26, 2019 Contacts/Locations and Study Status
514 September 27, 2019 Contacts/Locations and Study Status
515 September 30, 2019 Contacts/Locations and Study Status
516 October 2, 2019 Contacts/Locations and Study Status
517 October 3, 2019 Contacts/Locations and Study Status
518 October 4, 2019 Conditions and Study Status
519 October 7, 2019 Contacts/Locations and Study Status
520 October 9, 2019 Contacts/Locations and Study Status
521 October 10, 2019 Contacts/Locations and Study Status
522 October 11, 2019 Arms and Interventions and Study Status
523 October 14, 2019 Arms and Interventions and Study Status
524 October 15, 2019 Contacts/Locations and Study Status
525 October 17, 2019 Contacts/Locations and Study Status
526 October 21, 2019 Contacts/Locations and Study Status
527 October 23, 2019 Contacts/Locations and Study Status
528 October 24, 2019 Contacts/Locations and Study Status
529 October 25, 2019 Contacts/Locations and Study Status
530 October 28, 2019 Contacts/Locations and Study Status
531 October 30, 2019 Contacts/Locations and Study Status
532 October 31, 2019 Contacts/Locations and Study Status
533 November 1, 2019 Contacts/Locations and Study Status
534 November 4, 2019 Contacts/Locations and Study Status
535 November 5, 2019 Contacts/Locations and Study Status
536 November 6, 2019 Contacts/Locations and Study Status
537 November 7, 2019 Contacts/Locations and Study Status
538 November 12, 2019 Contacts/Locations and Study Status
539 November 14, 2019 Contacts/Locations and Study Status
540 November 15, 2019 Contacts/Locations and Study Status
541 November 18, 2019 Contacts/Locations, Arms and Interventions and Study Status
542 November 19, 2019 Contacts/Locations and Study Status
543 November 20, 2019 Contacts/Locations and Study Status
544 November 21, 2019 Contacts/Locations and Study Status
545 November 22, 2019 Contacts/Locations and Study Status
546 November 25, 2019 Contacts/Locations and Study Status
547 November 29, 2019 Contacts/Locations and Study Status
548 December 2, 2019 Contacts/Locations and Study Status
549 December 3, 2019 Contacts/Locations and Study Status
550 December 4, 2019 Contacts/Locations and Study Status
551 December 5, 2019 Contacts/Locations and Study Status
552 December 6, 2019 Contacts/Locations and Study Status
553 December 9, 2019 Contacts/Locations, Arms and Interventions and Study Status
554 December 12, 2019 Contacts/Locations and Study Status
555 December 13, 2019 Contacts/Locations and Study Status
556 December 16, 2019 Contacts/Locations and Study Status
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561 December 23, 2019 Contacts/Locations and Study Status
562 December 25, 2019 Contacts/Locations and Study Status
563 December 27, 2019 Contacts/Locations and Study Status
564 December 30, 2019 Contacts/Locations and Study Status
565 December 31, 2019 Contacts/Locations and Study Status
566 January 2, 2020 Contacts/Locations and Study Status
567 January 3, 2020 Contacts/Locations and Study Status
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577 January 20, 2020 Contacts/Locations, Arms and Interventions and Study Status
578 January 22, 2020 Contacts/Locations and Study Status
579 January 23, 2020 Contacts/Locations and Study Status
580 January 24, 2020 Contacts/Locations and Study Status
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582 January 28, 2020 Contacts/Locations and Study Status
583 January 29, 2020 Contacts/Locations and Study Status
584 January 30, 2020 Contacts/Locations and Study Status
585 January 31, 2020 Contacts/Locations and Study Status
586 February 3, 2020 Contacts/Locations, Arms and Interventions and Study Status
587 February 5, 2020 Contacts/Locations and Study Status
588 February 6, 2020 Contacts/Locations and Study Status
589 February 7, 2020 Contacts/Locations and Study Status
590 February 10, 2020 Contacts/Locations and Study Status
591 February 11, 2020 Contacts/Locations and Study Status
592 February 12, 2020 Contacts/Locations and Study Status
593 February 25, 2020 Contacts/Locations, Eligibility, Study Description, Oversight, Study Status and Study Identification
594 February 26, 2020 Contacts/Locations and Study Status
595 February 27, 2020 Contacts/Locations and Study Status
596 February 28, 2020 Contacts/Locations and Study Status
597 March 2, 2020 Contacts/Locations, Arms and Interventions and Study Status
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609 March 24, 2020 Contacts/Locations and Study Status
610 April 1, 2020 Contacts/Locations, Eligibility, Outcome Measures, Study Description, Study Status and Study Identification
611 April 2, 2020 Contacts/Locations and Study Status
612 April 3, 2020 Contacts/Locations and Study Status
613 April 7, 2020 Contacts/Locations and Study Status
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625 April 28, 2020 Contacts/Locations and Study Status
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627 April 30, 2020 Contacts/Locations and Study Status
628 May 2, 2020 Contacts/Locations, Arms and Interventions and Study Status
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712 September 29, 2020 Contacts/Locations and Study Status
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730 October 24, 2020 Contacts/Locations and Study Status
731 October 27, 2020 Contacts/Locations and Study Status
732 October 28, 2020 Contacts/Locations and Study Status
733 October 29, 2020 Contacts/Locations and Study Status
734 November 4, 2020 Contacts/Locations, Arms and Interventions and Study Status
735 November 6, 2020 Contacts/Locations and Study Status
736 November 7, 2020 Contacts/Locations and Study Status
737 November 10, 2020 Contacts/Locations and Study Status
738 November 12, 2020 Contacts/Locations and Study Status
739 November 13, 2020 Contacts/Locations and Study Status
740 November 14, 2020 Contacts/Locations and Study Status
741 November 17, 2020 Contacts/Locations and Study Status
742 November 18, 2020 Contacts/Locations and Study Status
743 November 19, 2020 Contacts/Locations and Study Status
744 November 21, 2020 Contacts/Locations and Study Status
745 November 24, 2020 Contacts/Locations and Study Status
746 November 25, 2020 Contacts/Locations and Study Status
747 December 1, 2020 Contacts/Locations and Study Status
748 December 12, 2020 Contacts/Locations and Study Status
749 December 15, 2020 Arms and Interventions and Study Status
750 December 19, 2020 Contacts/Locations and Study Status
751 December 22, 2020 Contacts/Locations and Study Status
752 December 23, 2020 Contacts/Locations and Study Status
753 December 24, 2020 Contacts/Locations and Study Status
754 December 29, 2020 Contacts/Locations and Study Status
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756 December 31, 2020 Contacts/Locations and Study Status
757 January 1, 2021 Contacts/Locations and Study Status
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767 January 19, 2021 Contacts/Locations and Study Status
768 January 20, 2021 Contacts/Locations and Study Status
769 January 22, 2021 Study Status
770 January 23, 2021 Contacts/Locations and Study Status
771 February 5, 2021 Recruitment Status, Study Status, Contacts/Locations, Eligibility, Study Design and Study Identification
772 February 6, 2021 Study Status
773 February 9, 2021 Recruitment Status, Study Status and Contacts/Locations
774 February 10, 2021 Contacts/Locations and Study Status
775 February 11, 2021 Contacts/Locations and Study Status
776 February 12, 2021 Contacts/Locations and Study Status
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787 February 27, 2021 Contacts/Locations, Study Design and Study Status
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817 April 23, 2021 Contacts/Locations and Study Status
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820 April 30, 2021 Contacts/Locations and Study Status
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833 May 22, 2021 Contacts/Locations and Study Status
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843 June 10, 2021 Contacts/Locations and Study Status
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852 June 26, 2021 Contacts/Locations and Study Status
853 June 29, 2021 Contacts/Locations and Study Status
854 June 30, 2021 Contacts/Locations and Study Status
855 July 1, 2021 Recruitment Status, Study Status and Contacts/Locations
856 July 2, 2021 Study Status
857 July 30, 2021 Study Status
858 August 3, 2021 Study Status
859 August 18, 2021 Contacts/Locations and Study Status
860 August 26, 2021 Contacts/Locations and Study Status
861 September 25, 2021 Contacts/Locations and Study Status
862 October 8, 2021 Contacts/Locations and Study Status
863 November 30, 2021 Oversight and Study Status
864 December 8, 2021 Study Status
865 December 22, 2021 Contacts/Locations and Study Status
866 February 26, 2022 Contacts/Locations and Study Status
867 April 5, 2022 Study Status
868 April 28, 2022 Contacts/Locations and Study Status
869 April 29, 2022 Contacts/Locations and Study Status
870 May 27, 2022 Contacts/Locations and Study Status
871 June 7, 2022 Arms and Interventions and Study Status
872 June 10, 2022 Contacts/Locations and Study Status
873 June 18, 2022 Contacts/Locations and Study Status
874 June 25, 2022 Contacts/Locations and Study Status
875 June 29, 2022 Study Status and Arms and Interventions
876 July 20, 2022 Contacts/Locations and Study Status
877 August 5, 2022 Contacts/Locations and Study Status
878 August 30, 2022 Contacts/Locations and Study Status
879 September 23, 2022 Contacts/Locations and Study Status
880 October 18, 2022 Contacts/Locations and Study Status
881 December 30, 2022 Contacts/Locations and Study Status
882 January 27, 2023 Study Status
883 January 28, 2023 Contacts/Locations and Study Status
884 February 10, 2023 Contacts/Locations and Study Status
885 March 7, 2023 Arms and Interventions and Study Status
886 March 29, 2023 Contacts/Locations and Study Status
887 April 19, 2023 Arms and Interventions, Eligibility, Conditions, Study Description and Study Status
888 April 27, 2023 Study Status
889 May 2, 2023 Contacts/Locations, Arms and Interventions and Study Status
890 May 13, 2023 Study Status
891 June 16, 2023 Contacts/Locations and Study Status
892 July 14, 2023 Contacts/Locations and Study Status
893 July 28, 2023 Contacts/Locations and Study Status
894 August 8, 2023 Arms and Interventions and Study Status
895 September 9, 2023 Contacts/Locations and Study Status
896 September 20, 2023 Contacts/Locations and Study Status
897 September 29, 2023 Study Status and Oversight
898 December 2, 2023 Study Status
899 January 6, 2024 Contacts/Locations and Study Status
900 January 9, 2024 Contacts/Locations and Study Status
901 February 14, 2024 Contacts/Locations and Study Status
902 April 3, 2024 Contacts/Locations and Study Status
903 May 7, 2024 Arms and Interventions and Study Status
904 May 15, 2024 Contacts/Locations and Study Status
905 May 16, 2024 Contacts/Locations and Study Status
906 May 18, 2024 Contacts/Locations and Study Status
Comparison Format:
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Study NCT02954874
Submitted Date:  April 28, 2022 (v868)
Open or close this module Study Identification
Unique Protocol ID: NCI-2016-01595
Brief Title: Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer
Official Title: A Randomized, Phase III Trial to Evaluate the Efficacy and Safety of Pembrolizumab (MK-3475) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer With >/= 1 CM Residual Invasive Cancer or Positive Lymph Nodes (ypN1mi, ypN1-3) After Neoadjuvant Chemotherapy
Secondary IDs: NCI-2016-01595 [Registry Identifier: CTRP (Clinical Trial Reporting Program)]
S1418/BR006
s16-02231
S1418 [SWOG]
S1418 [CTEP]
U10CA180888 [U.S. NIH Grant/Contract]
Open or close this module Study Status
Record Verification: December 2021
Overall Status: Active, not recruiting
Study Start: November 15, 2016
Primary Completion: May 31, 2026 [Anticipated]
Study Completion: May 31, 2026 [Anticipated]
First Submitted: November 3, 2016
First Submitted that
Met QC Criteria:		 November 3, 2016
First Posted: November 4, 2016 [Estimate]
Last Update Submitted that
Met QC Criteria:		 April 28, 2022
Last Update Posted: April 29, 2022 [Actual]
Open or close this module Sponsor/Collaborators
Sponsor: National Cancer Institute (NCI)
Responsible Party: Sponsor
Collaborators:
Open or close this module Oversight
U.S. FDA-regulated Drug:
U.S. FDA-regulated Device:
Data Monitoring: No
Open or close this module Study Description
Brief Summary: This randomized phase III trial studies how well pembrolizumab works in treating patients with triple-negative breast cancer. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
Detailed Description:

PRIMARY OBJECTIVE:

I. To compare invasive disease-free survival (IDFS) of patients with triple-negative (TNBC) or low estrogen receptor (ER)-positive and/or HER2 borderline breast cancer who have >= 1 cm residual invasive breast cancer and/or positive lymph nodes (ypN1mi, ypN1, ypN2, ypN3) after neoadjuvant chemotherapy randomized to receive 1 year of MK-3475 (pembrolizumab) adjuvant therapy compared to no MK-3475 (pembrolizumab), in both the entire study population and also in the PD-L1 positive subset.

SECONDARY OBJECTIVES:

I. To compare the effects of MK-3475 (pembrolizumab) on overall survival (OS) and distant recurrence-free survival (DRFS) between the two randomized arms for the PD-L1 positive patients and then all patients.

II. To assess the toxicity and tolerability of MK-3475 (pembrolizumab) in this patient population with or without radiation therapy.

BEHAVIORAL AND HEALTH OUTCOMES (BAHO) STUDY OBJECTIVES:

I. To examine the association between biomarkers of inflammation and quality of life and patient reported outcomes between the two groups during and at the end of therapy.

II. To examine the long-term and late effects of treatment on patient-reported outcomes.

ADDITIONAL OBJECTIVE:

I. To collect tissue and whole blood for processing and banking in anticipation of future correlative studies in this patient population.

OUTLINE: Patients are randomized to 1 of 2 arms.

ARM I (OBSERVATION): Patients receive no treatment but are monitored at standard clinical intervals during first year after randomization. Patients are examined every 12 weeks for 1 year, and every 6 months for 4 years, then annually for 5 years.

ARM II (PEMBROLIZUMAB): Patients receive pembrolizumab intravenously (IV) over 30 minutes on days 1 and 22. Cycles repeat every 42 days for 52 weeks in the absence of disease progression or unacceptable toxicity.

All patients may undergo radiation therapy within 12 weeks of last breast cancer operation or after treatment.

After completion of study treatment, patients are followed up every 6 months for 5 years, then annually thereafter until 10 years from treatment randomization.
Open or close this module Conditions
Conditions: Invasive Breast Carcinoma
Stage 0 Breast Cancer AJCC v6 and v7
Stage I Breast Cancer AJCC v7
Stage IA Breast Cancer AJCC v7
Stage IB Breast Cancer AJCC v7
Stage II Breast Cancer AJCC v6 and v7
Stage IIA Breast Cancer AJCC v6 and v7
Stage IIB Breast Cancer AJCC v6 and v7
Stage III Breast Cancer AJCC v7
Stage IIIA Breast Cancer AJCC v7
Stage IIIB Breast Cancer AJCC v7
Stage IIIC Breast Cancer AJCC v7
Triple-Negative Breast Carcinoma
Keywords:
Open or close this module Study Design
Study Type: Interventional
Primary Purpose: Treatment
Study Phase: Phase 3
Interventional Study Model: Parallel Assignment
Number of Arms: 2
Masking: None (Open Label)
Allocation: Randomized
Enrollment: 1155 [Anticipated]
Open or close this module Arms and Interventions
Arms Assigned Interventions
Experimental: Arm I (observation)
Patients receive no treatment but are monitored at standard clinical intervals during first year after randomization. Patients are examined every 12 weeks for 1 year, every 6 months for 4 years, and then annually for 5 years. Patients may undergo radiation therapy within 12 weeks of last breast cancer operation or after treatment.
Laboratory Biomarker Analysis
Correlative studies
Patient Observation
Undergo standard monitoring
Other Names:
  • Active Surveillance
  • deferred therapy
  • expectant management
  • Observation
  • Watchful Waiting
Quality-of-Life Assessment
Ancillary studies
Other Names:
  • Quality of Life Assessment
Questionnaire Administration
Ancillary studies
Radiation: Radiation Therapy
Undergo radiation therapy
Other Names:
  • Cancer Radiotherapy
  • ENERGY_TYPE
  • Irradiate
  • Irradiated
  • Irradiation
  • Radiation
  • Radiation Therapy, NOS
  • Radiotherapeutics
  • Radiotherapy
  • RT
  • Therapy, Radiation
Experimental: Arm II (pembrolizumab)
Patients receive pembrolizumab IV over 30 minutes on days 1 and 22. Cycles repeat every 42 days for 52 weeks in the absence of disease progression or unacceptable toxicity. Patients may undergo radiation therapy within 12 weeks of last breast cancer operation or after treatment.
Laboratory Biomarker Analysis
Correlative studies
Biological: Pembrolizumab
Given IV
Other Names:
  • Keytruda
  • Lambrolizumab
  • MK-3475
  • SCH 900475
Quality-of-Life Assessment
Ancillary studies
Other Names:
  • Quality of Life Assessment
Questionnaire Administration
Ancillary studies
Radiation: Radiation Therapy
Undergo radiation therapy
Other Names:
  • Cancer Radiotherapy
  • ENERGY_TYPE
  • Irradiate
  • Irradiated
  • Irradiation
  • Radiation
  • Radiation Therapy, NOS
  • Radiotherapeutics
  • Radiotherapy
  • RT
  • Therapy, Radiation
Open or close this module Outcome Measures
Primary Outcome Measures:
1. Invasive disease-free survival (IDFS)
[ Time Frame: From date of randomization to date of first invasive recurrence, second invasive primary cancer (breast or not), or death due to any cause, assessed up to 10 years ]

The distributions of IDFS will be estimated using the Kaplan-Meier method, with 95% confidence intervals (CI) calculated using Greenwood's formula. Comparisons between the two treatment arms will be performed using the stratified log-rank test. The hazard ratios and 95% CIs will be based on the stratified Cox proportional hazard model with treatment as the only covariate. Secondary analyses of IDFS will be performed to describe consistency or divergence across subgroups. This will include a forest plot of treatment hazard ratios and associated 95% confidence intervals for each level of the stratification factors and major prognostic covariates (such as use of radiation therapy). The statistical significance of the interaction between treatment and each stratification factor or prognostic variable will be assessed.
2. Severity of fatigue
[ Time Frame: 55 weeks after randomization ]

Measured by Patient Reported Outcomes Measurement Information System (PROMIS) fatigue scale. Will be compared between the two treatment groups by means of multiple linear regression with adjustment for the corresponding baseline measurement as well as whether or not the patient received radiation therapy which is known to be associated with post-treatment fatigue. No multiple comparisons adjustment will be employed since these outcomes evaluate the toxicity of the investigational drug. The clinical meaningfulness of each comparison will be considered.
3. Physical function
[ Time Frame: 55 weeks after randomization ]

Reported by patients measured by PROMIS Global physical health scale. Will be compared between the two treatment groups by means of multiple linear regression with adjustment for the corresponding baseline measurement as well as whether or not the patient received radiation therapy which is known to be associated with post-treatment fatigue. No multiple comparisons adjustment will be employed since these outcomes evaluate the toxicity of the investigational drug. The clinical meaningfulness of each comparison will be considered.
Secondary Outcome Measures:
1. Overall survival (OS)
[ Time Frame: From date of randomization to date of death due to any cause, assessed up to 10 years ]

The distributions of OS will be estimated using the Kaplan-Meier method, with 95% CI calculated using Greenwood's formula. Comparisons between the two treatment arms will be performed using the stratified log-rank test. The hazard ratios and 95% CIs will be based on the stratified Cox proportional hazard model with treatment as the only covariate.
2. Distant recurrence-free survival (DRFS)
[ Time Frame: From date of randomization to date of invasive distant disease recurrence, second invasive primary cancer (breast or not) or death due to any cause, assessed up to 10 years ]

The distributions of DRFS will be estimated using the Kaplan-Meier method, with 95% CI calculated using Greenwood's formula. Comparisons between the two treatment arms will be performed using the stratified log-rank test. The hazard ratios and 95% CIs will be based on the stratified Cox proportional hazard model with treatment as the only covariate.
3. Incidence of adverse events
[ Time Frame: Up to 10 years ]

Assessed by National Cancer Institute Common Terminology Criteria for Adverse Events version 4.0. Toxicity analysis will be conducted in all patients receiving at least one dose of MK-3475 (pembrolizumab). The incidence of adverse events will be reported.
4. Severity and frequency of treatment-related symptoms (diarrhea, nausea, rash, cough, and shortness of breath, musculoskeletal pain) over time of patients receiving pembrolizumab
[ Time Frame: Up to 10 years ]

Compared without treatment. The distributions of the corresponding Patient Reported Outcomes version of Common Terminology Criteria for Adverse Events (PRO-CTCAE) items will be compared between the two treatment groups using a mixed ordinal logistic regression model for repeated measures. The model will also include the corresponding baseline measurement and time. Presence of treatment-by-time interaction will be tested for each of these endpoints. Similar analyses will be performed for disease related symptoms. The descriptive and graphical methods suggested in Basch, et. al. will be used to summarize the distributions of different symptoms by treatment group over time.
5. Emotional function and disease-related symptoms in patients receiving pembrolizumab
[ Time Frame: Up to 10 years ]

Assessed by PROMIS global mental health scale score. Will be compared between the two treatment groups using a mixed model for repeated measures analysis with adjustment for the baseline score and time. Presence of treatment-by-time interaction will be investigated.
6. Impact of treatment and treatment-related symptoms on physical function in patients without therapy
[ Time Frame: 55 weeks after randomization ]

Compared to patients receiving pembrolizumab. A multiple linear regression model will be performed with physical health scale score as an outcome and treatment and treatment related symptoms as covariates. Presence of treatment by each individual symptom item interactions will be investigated.
7. Relationship between treatment-related symptoms and adherence to the study medication
[ Time Frame: Up to 10 years ]

Will be investigated among patients randomized to pembrolizumab treatment group by means of multiple logistic regression. Patients who have been on study therapy for 70% or more of their expected time on therapy will be considered adherent.
8. Resolution of treatment-related symptoms in patients receiving pembrolizumab
[ Time Frame: 18 months after randomization ]

Compared to patients without treatment. A change in severity of the particular symptom will be compared between the two treatment groups by means of multiple linear regression with adjustment for the corresponding measurement at the 55 week assessment point.
9. Long-term quality of life and symptoms between the two treatment groups
[ Time Frame: Up to 60 months after randomization ]

Mixed models for repeated measures analysis will be used with adjustment for scores at 18 months to examine changes in physical and emotional domain scores, fatigue and other persistent symptoms over the course
10. Role of pro-inflammatory cytokines in the development of pembrolizumab associated symptoms
[ Time Frame: Up to 55 weeks ]

Specifically focused on treatment-associated fatigue. This will be compared to patients in the observation group.
11. Single nucleotide polymorphisms (SNPs) in the promotor region of pro-inflammatory cytokine genes and the risk for development and severity of treatment-associated fatigue and other symptoms
[ Time Frame: Up to 10 years ]

The role of these SNPs in the persistence of long-term fatigue in all patients will also be explored using treatment assignment as a covariate.
Open or close this module Eligibility
Minimum Age: 18 Years
Maximum Age:
Sex: All
Gender Based:
Accepts Healthy Volunteers: No
Criteria:

Inclusion Criteria:

  • STEP 1 REGISTRATION
  • Patients must have histologically confirmed estrogen receptor (ER)-, progesterone receptor (PR)- and HER2-negative (triple-negative, TNBC) or ER-, PR- weakly positive and/or HER2- equivocal status and must not have received and not be planning to receive adjuvant anti-HER2 or endocrine therapies after completion of neoadjuvant chemotherapy; patients who are HER2-positive by American Society of Clinical Oncology (ASCO) College of American Pathologists (CAP) guidelines are ineligible; HER2-negative and HER2-equivocal cases as per ASCO CAP guidelines that do not receive HER2-targeted therapy are eligible; patients with weakly ER or PR positive disease, defined as ER and/or PR less than or equal to (=<) 5% by immunohistochemistry, are eligible if the treating physician considers the patient not eligible for adjuvant endocrine therapy; residual disease must be >= 1 cm in greatest dimension, and/or have positive lymph nodes (ypN1mi, ypN1, ypN2, ypN3) observed on pathologic exam
    • NOTE: If the ER and/or HER2 results are discordant between the initial, pre-chemotherapy, and post-chemotherapy surgical tissue, the receptor status of the residual disease has to be used to determine eligibility. Immunohistochemistry (IHC)-positive isolated tumor cells in the lymph node (N0 [i+]) are not considered node-positive and these patients also must have >= 1 cm residual invasive cancer in the breast to be eligible.
  • Patients must not have metastatic disease (i.e., must be clinically M0 or Mx; systemic staging studies with imaging should follow routine practice as per National Comprehensive Cancer Network [NCCN] and ASCO guidelines); patients must not have locally recurrent disease
  • It is preferred that axillary lymph node sampling is performed after completion of neoadjuvant chemotherapy to allow more accurate assessment of pathologic response; complete axillary lymph node dissection (ALND) after neoadjuvant chemotherapy is recommended in the following situations:
    • Patients had documented pathologic involvement of the axillary nodes (fine needle aspiration [FNA] or core biopsy) before neoadjuvant chemotherapy and had sentinel node biopsy after neoadjuvant chemotherapy with positive sentinel node(s)
    • Patient had documented pathologic involvement of the axillary nodes (FNA or core biopsy) before neoadjuvant chemotherapy and had only 1 sentinel lymph node removed after neoadjuvant chemotherapy
      • Except for (i) patients participating in the Alliance A11202 trial) or (ii) if the treating surgeon determines that a complete ALND is not in the best interest of the patient
      • NOTE: Patients who undergo sentinel node biopsy before starting neoadjuvant treatment and do not undergo post neoadjuvant assessment of the axillary nodes or who have negative axillary nodes on post neoadjuvant assessment must have >= 1 cm residual invasive cancer in the breast after completion of neoadjuvant chemotherapy
  • Patients must have a minimum of five, available unstained formalin-fixed paraffin-embedded (FFPE) slides (4-5 micron thickness) from the residual (post-neoadjuvant) invasive tumor in primary site or lymph node; (these will be submitted to a central laboratory to determine PD-L1 expression); the tumor tissue must be adequate for PD-L1 testing, which typically requires a minimum of 100 cancer cells per slide; local PD-L1 results, even if available, will not substitute for central testing
    • NOTE: Initial order for specimen kits should be placed at least two weeks prior to registering the first patient at each site
  • Patients must be offered the opportunity to participate in specimen banking
  • The BAHO substudy was permanently closed to accrual on June 23, 2020, and willingness of English-speaking patients to participate in the BAHO substudy is no longer applicable
  • Patients must have had neoadjuvant chemotherapy followed by surgery; the choice of neoadjuvant chemotherapy is determined by the treating physician; we recommend following the National Comprehensive Cancer Network (NCCN) treatment guidelines for TNBC; patients who cannot complete all planned treatment cycles for any reason are considered high risk and therefore are eligible for the study if they have residual disease; patients must have resolution of adverse event(s) of the most recent prior chemotherapy to grade 1 or less, except alopecia and =< grade 2 neuropathy which are allowed
  • Patients may receive post-operative (adjuvant) chemotherapy for up to 24 weeks of duration (e.g. 8 cycles of capecitabine as in the Capecitabine for Residual Cancer as Adjuvant Therapy (CREATE-X) trial; the 24-week duration does not include treatment delays) after completion of surgery at the discretion of the treating physician; co-enrollment to EA1131 is allowed, provided that patients complete or discontinue adjuvant chemotherapy prior to step 1 registration; at the time of step 1 registration, patients must have resolution of adverse event(s) of the most recent prior chemotherapy to =< grade 1, except alopecia and =< grade 2 neuropathy which are allowed; patients that have received adjuvant chemotherapy (including via co-enrollment to EA1131) must be registered to step 1 within 35 days after final dose of adjuvant chemotherapy
  • Patients must have completed their final breast surgery (rendering them free from disease) with clear resection margins for invasive cancer and DCIS within the following timelines:
    • 90 days prior to step 1 screening registration for patients not receiving post-operative (adjuvant) chemotherapy OR
    • 270 days prior to step 1 screening registration for patients who have received post-operative (adjuvant) chemotherapy Positive margins are allowed only if the surgical team of the patient deems further resection impossible
  • Patients for whom radiation therapy (RT) to the affected breast or chest wall and regional nodal areas is clinically indicated as per NCCN treatment guidelines, should receive routine RT after randomization when possible, and receive MK-3475 (pembrolizumab) concurrent with RT, if randomized to the experimental arm; however, routine RT administered, or initiated, prior to registration is also allowed; MK-3475 (pembrolizumab) may be added to ongoing radiation, or started after its completion, if randomized to the experimental arm, provided there are no > grade 1 radiation-related skin toxicities and provided that no radiosensitizing chemotherapy is being administered; co-enrollment in the Alliance A221505 (NCT03414970) and A011202 (NCT01901094) trials or in the NSABP-B51 (NCT01872975) trial is allowed, but patients must not be planning to receive radiation therapy given on these trials concurrently with MK-3475 (pembrolizumab) treatment on S1418/BR006; whether or not patient will receive RT and the extent of intended RT must be specified at time of registration; NOTE: Patients who receive post-operative chemotherapy may receive radiation therapy before or after the chemotherapy; a short course of reduced dose chemotherapy or other agents concomitant with radiation for radiation sensitization is not considered to be adjuvant chemotherapy
  • Patients must not have had prior immunotherapy with anti-PD-L1, anti-PD-1, anti-CTLA4 or similar drugs; patients must not be planning to receive any of the prohibited therapies during the screening or treatment phases of the study
  • Patients must not be planning to receive concomitantly other biologic therapy, hormonal therapy, other chemotherapy, surgery or other anti-cancer therapy except radiation therapy while receiving treatment on this protocol; however, patients receiving extended adjuvant endocrine therapy for an earlier ER positive breast cancer treated with curative intent and without recurrence for at least 5 years may continue with their endocrine therapy; elective surgery or surgery that is not related to cancer therapy is allowed, at the discretion of the treating investigator
  • Patients must have Zubrod performance status =< 2
  • Patients must not have a history of (non-infectious) pneumonitis that required steroids or evidence of active pneumonitis within 2 years prior to registration
  • Patients must not have active autoimmune disease that has required systemic treatment in past 2 years (i.e., with use of disease modifying agents, corticosteroids or immunosuppressive drugs); replacement therapy (e.g., thyroxine for pre-existing hypothyroidism, insulin for type I diabetes mellitus, or physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency, etc.) is not considered a form of systemic treatment
  • Patients must not have received live vaccines within 30 days prior to registration; examples of live vaccines include, but are not limited to, the following: measles, mumps, rubella, chicken pox, shingles, yellow fever, rabies, Bacillus Calmette-Guerin (BCG), and typhoid (oral) vaccine; seasonal influenza vaccines for injection are generally killed virus vaccines and are allowed; however, intranasal influenza vaccines (e.g., Flu-Mist) are live attenuated vaccines, and are not allowed
  • Patients must not have known active hepatitis B virus (HBV) or hepatitis C virus (HCV) infection prior to registration; patients who have completed curative therapy for HCV are eligible; patients with known human immunodeficiency virus (HIV) infection are eligible if they meet each of the following 3 criteria:
    • CD4 counts >= 350 mm^3
    • Serum HIV viral load of < 25,000 IU/ml and
    • Treated on a stable antiretroviral regimen
  • No other prior invasive malignancy is allowed except for the following: adequately treated basal (or squamous cell) skin cancer, in situ breast or cervical cancer; stage I or II invasive cancer treated with a curative intent without evidence of disease recurrence for at least five years
  • Patients must have complete history and physical examination within 28 days prior to registration
  • Patients must be informed of the investigational nature of this study and must sign and give written informed consent for this protocol in accordance with institutional and federal guidelines
  • As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system
  • STEP 2 REGISTRATION
  • Patients must not be registered to step 2 until receiving confirmation from the Southwest Oncology Group (SWOG) Statistical and Data Management Center that the patient's tissue specimen was adequate for PD-L1 testing; patients must be registered within 14 days of receiving the e-mail notification confirming submission was evaluable for PD-L1 status
  • Absolute neutrophil count (ANC) >= 1,500 microliter (mcL) (obtained within 28 days prior to step 2 registration)
  • Platelets >= 100,000/mcL (obtained within 28 days prior to step 2 registration)
  • Hemoglobin >= 9 g/dL (obtained within 28 days prior to step 2 registration)
  • A serum thyroid-stimulating hormone (TSH) and/or free T4 must be obtained within 28 days prior to step 2 registration to obtain a baseline value
  • Total bilirubin =< 1.5 x institutional upper limit of normal (IULN) (except Gilbert's syndrome, who must have a total bilirubin < 3.0 mg/dL) (obtained within 28 days prior to step 2 registration)
  • Serum glutamic-oxaloacetic transaminase (SGOT) (aspartate aminotransferase [AST]) or serum glutamate pyruvate transaminase (SGPT) (alanine aminotransferase [ALT]) =< 2.5 x IULN (obtained within 28 days prior to step 2 registration)
  • Alkaline phosphatase =< 2.5 x IULN (obtained within 28 days prior to step 2 registration)
  • Serum creatinine =< IULN OR measured or calculated creatinine clearance >= 60 mL/min (obtained within 28 days prior to step 2 registration)
  • Women of childbearing potential must have a negative urine or serum pregnancy test within 28 day prior to registration; women/men of reproductive potential must have agreed to use an effective contraceptive method for the course of the study through 120 days after the last dose of study medication; should a woman become pregnant or suspect she is pregnant while she or her partner is participating in this study, she should inform her treating physician immediately; a woman is considered to be of "reproductive potential" if she has had menses at any time in the preceding 12 consecutive months; in addition to routine contraceptive methods, "effective contraception" also includes heterosexual celibacy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy, bilateral oophorectomy, bilateral tubal ligation, or vasectomy; however, if at any point a previously celibate patient chooses to become heterosexually active during the time period for use of contraceptive measures outlined in the protocol, he/she is responsible for beginning contraceptive measures; patients must not be pregnant or nursing; women of childbearing potential must plan to have a urine or serum pregnancy test within 72 hours prior to receiving the first dose of study medication; if the urine test is positive or cannot be confirmed as negative, a negative serum pregnancy test will be required
  • Patients must not have an active infection requiring systemic therapy at the time of starting therapy
  • Site must verify that there is no known change in the step 1 eligibility since initial registration
Open or close this module Contacts/Locations
Study Officials: Lajos Pusztai
Principal Investigator
SWOG Cancer Research Network
Locations: United States, Alabama
University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, United States, 35233
Southern Cancer Center PC-Daphne
Daphne, Alabama, United States, 36526
Southern Cancer Center PC-Mobile
Mobile, Alabama, United States, 36607
Southern Cancer Center PC-Providence
Mobile, Alabama, United States, 36608
Southern Cancer Center PC-Springhill
Mobile, Alabama, United States, 36608
University of South Alabama Mitchell Cancer Institute
Mobile, Alabama, United States, 36688
United States, Alaska
Alaska Oncology and Hematology LLC
Anchorage, Alaska, United States, 99508
Anchorage Oncology Centre
Anchorage, Alaska, United States, 99508
Katmai Oncology Group
Anchorage, Alaska, United States, 99508
Providence Alaska Medical Center
Anchorage, Alaska, United States, 99508
Fairbanks Memorial Hospital
Fairbanks, Alaska, United States, 99701
United States, Arizona
Banner MD Anderson Cancer Center
Gilbert, Arizona, United States, 85234
CTCA at Western Regional Medical Center
Goodyear, Arizona, United States, 85338
Banner University Medical Center - Tucson
Tucson, Arizona, United States, 85719
University of Arizona Cancer Center-North Campus
Tucson, Arizona, United States, 85719
United States, Arkansas
Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
Jonesboro, Arkansas, United States, 72401
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States, 72205
Highlands Oncology Group
Rogers, Arkansas, United States, 72758
United States, California
Kaiser Permanente-Anaheim
Anaheim, California, United States, 92806
Kaiser Permanente-Deer Valley Medical Center
Antioch, California, United States, 94531
PCR Oncology
Arroyo Grande, California, United States, 93420
Sutter Auburn Faith Hospital
Auburn, California, United States, 95602
AIS Cancer Center at San Joaquin Community Hospital
Bakersfield, California, United States, 93301
Kaiser Permanente-Baldwin Park
Baldwin Park, California, United States, 91706
Kaiser Permanente-Bellflower
Bellflower, California, United States, 90706
Alta Bates Summit Medical Center-Herrick Campus
Berkeley, California, United States, 94704
Mills-Peninsula Medical Center
Burlingame, California, United States, 94010
Community Cancer Institute
Clovis, California, United States, 93611
City of Hope Corona
Corona, California, United States, 92879
UC Irvine Health Cancer Center-Newport
Costa Mesa, California, United States, 92627
City of Hope Comprehensive Cancer Center
Duarte, California, United States, 91010
Epic Care-Dublin
Dublin, California, United States, 94568
Bay Area Breast Surgeons Inc
Emeryville, California, United States, 94608
Epic Care Partners in Cancer Care
Emeryville, California, United States, 94608
Kaiser Permanente-Fontana
Fontana, California, United States, 92335
Kaiser Permanente-Fremont
Fremont, California, United States, 94538
Palo Alto Medical Foundation-Fremont
Fremont, California, United States, 94538
Washington Hospital
Fremont, California, United States, 94538
Kaiser Permanente-Fresno
Fresno, California, United States, 93720
Saint Jude Medical Center
Fullerton, California, United States, 92835
Marin Cancer Care Inc
Greenbrae, California, United States, 94904
Kaiser Permanente - Harbor City
Harbor City, California, United States, 90710
Kaiser Permanente-Irvine
Irvine, California, United States, 92618
Loma Linda University Medical Center
Loma Linda, California, United States, 92354
Kaiser Permanente Los Angeles Medical Center
Los Angeles, California, United States, 90027
Los Angeles County-USC Medical Center
Los Angeles, California, United States, 90033
USC / Norris Comprehensive Cancer Center
Los Angeles, California, United States, 90033
Kaiser Permanente West Los Angeles
Los Angeles, California, United States, 90034
Contra Costa Regional Medical Center
Martinez, California, United States, 94553-3156
Fremont - Rideout Cancer Center
Marysville, California, United States, 95901
City of Hope Mission Hills
Mission Hills, California, United States, 91345
Memorial Medical Center
Modesto, California, United States, 95355
Kaiser Permanente-Modesto
Modesto, California, United States, 95356
Community Hospital of Monterey Peninsula
Monterey, California, United States, 93940
Palo Alto Medical Foundation-Camino Division
Mountain View, California, United States, 94040
Palo Alto Medical Foundation-Gynecologic Oncology
Mountain View, California, United States, 94040
USC Norris Oncology/Hematology-Newport Beach
Newport Beach, California, United States, 92663
Sutter Cancer Research Consortium
Novato, California, United States, 94945
Alta Bates Summit Medical Center - Summit Campus
Oakland, California, United States, 94609
Bay Area Tumor Institute
Oakland, California, United States, 94609
Kaiser Permanente-Oakland
Oakland, California, United States, 94611
Kaiser Permanente-Ontario
Ontario, California, United States, 91761
Saint Joseph Hospital - Orange
Orange, California, United States, 92868
UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California, United States, 92868
Desert Regional Medical Center
Palm Springs, California, United States, 92262
Palo Alto Medical Foundation Health Care
Palo Alto, California, United States, 94301
Stanford Cancer Institute Palo Alto
Palo Alto, California, United States, 94304
Kaiser Permanente - Panorama City
Panorama City, California, United States, 91402
Huntington Memorial Hospital
Pasadena, California, United States, 91105
Kaiser Permanente-Redwood City
Redwood City, California, United States, 94063
Kaiser Permanente-Richmond
Richmond, California, United States, 94801
Kaiser Permanente-Riverside
Riverside, California, United States, 92505
Kaiser Permanente-Roseville
Roseville, California, United States, 95661
Sutter Roseville Medical Center
Roseville, California, United States, 95661
Kaiser Permanente Downtown Commons
Sacramento, California, United States, 95814
Sutter Medical Center Sacramento
Sacramento, California, United States, 95816
University of California Davis Comprehensive Cancer Center
Sacramento, California, United States, 95817
Kaiser Permanente - Sacramento
Sacramento, California, United States, 95825
Salinas Valley Memorial
Salinas, California, United States, 93901
Kaiser Permanente-San Diego Mission
San Diego, California, United States, 92108
Kaiser Permanente-San Diego Zion
San Diego, California, United States, 92120
California Pacific Medical Center-Pacific Campus
San Francisco, California, United States, 94115
Kaiser Permanente-San Francisco
San Francisco, California, United States, 94115
Kaiser Permanente-Santa Teresa-San Jose
San Jose, California, United States, 95119
Stanford Cancer Center South Bay
San Jose, California, United States, 95124
Kaiser Permanente San Leandro
San Leandro, California, United States, 94577
Pacific Central Coast Health Center-San Luis Obispo
San Luis Obispo, California, United States, 93401
Kaiser Permanente-San Marcos
San Marcos, California, United States, 92078
Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California, United States, 95051
Palo Alto Medical Foundation-Santa Cruz
Santa Cruz, California, United States, 95065
Mission Hope Medical Oncology - Santa Maria
Santa Maria, California, United States, 93444
Kaiser Permanente-Santa Rosa
Santa Rosa, California, United States, 95403
Providence Medical Foundation - Santa Rosa
Santa Rosa, California, United States, 95403
City of Hope South Pasadena
South Pasadena, California, United States, 91030
Kaiser Permanente-South San Francisco
South San Francisco, California, United States, 94080
Kaiser Permanente-Stockton
Stockton, California, United States, 95210
Palo Alto Medical Foundation-Sunnyvale
Sunnyvale, California, United States, 94086
Gene Upshaw Memorial Tahoe Forest Cancer Center
Truckee, California, United States, 96161
City of Hope Upland
Upland, California, United States, 91786
Kaiser Permanente Medical Center-Vacaville
Vacaville, California, United States, 95688
Kaiser Permanente-Vallejo
Vallejo, California, United States, 94589
Sutter Solano Medical Center/Cancer Center
Vallejo, California, United States, 94589
Kaiser Permanente-Walnut Creek
Walnut Creek, California, United States, 94596
Presbyterian Intercommunity Hospital
Whittier, California, United States, 90602
Kaiser Permanente-Woodland Hills
Woodland Hills, California, United States, 91367
United States, Colorado
Rocky Mountain Cancer Centers-Aurora
Aurora, Colorado, United States, 80012
University of Colorado Hospital
Aurora, Colorado, United States, 80045
Rocky Mountain Cancer Centers-Boulder
Boulder, Colorado, United States, 80304
Penrose-Saint Francis Healthcare
Colorado Springs, Colorado, United States, 80907
UCHealth Memorial Hospital Central
Colorado Springs, Colorado, United States, 80909
Memorial Hospital North
Colorado Springs, Colorado, United States, 80920
Kaiser Permanente-Franklin
Denver, Colorado, United States, 80205
National Jewish Health-Main Campus
Denver, Colorado, United States, 80206
Porter Adventist Hospital
Denver, Colorado, United States, 80210
Rocky Mountain Cancer Centers-Midtown
Denver, Colorado, United States, 80218
SCL Health Saint Joseph Hospital
Denver, Colorado, United States, 80218
Rocky Mountain Cancer Centers-Rose
Denver, Colorado, United States, 80220
Mountain Blue Cancer Care Center - Swedish
Englewood, Colorado, United States, 80113
Swedish Medical Center
Englewood, Colorado, United States, 80113
Poudre Valley Hospital
Fort Collins, Colorado, United States, 80524
Cancer Care and Hematology-Fort Collins
Fort Collins, Colorado, United States, 80528
National Jewish Health-Western Hematology Oncology
Golden, Colorado, United States, 80401
Grand Valley Oncology
Grand Junction, Colorado, United States, 81505
North Colorado Medical Center
Greeley, Colorado, United States, 80631
UCHealth Greeley Hospital
Greeley, Colorado, United States, 80631
Good Samaritan Medical Center
Lafayette, Colorado, United States, 80026
Kaiser Permanente-Rock Creek
Lafayette, Colorado, United States, 80026
Saint Anthony Hospital
Lakewood, Colorado, United States, 80228
Rocky Mountain Cancer Centers-Littleton
Littleton, Colorado, United States, 80120
Littleton Adventist Hospital
Littleton, Colorado, United States, 80122
Kaiser Permanente-Lone Tree
Lone Tree, Colorado, United States, 80124
Rocky Mountain Cancer Centers-Sky Ridge
Lone Tree, Colorado, United States, 80124
Longmont United Hospital
Longmont, Colorado, United States, 80501
Medical Center of the Rockies
Loveland, Colorado, United States, 80538
McKee Medical Center
Loveland, Colorado, United States, 80539
Parker Adventist Hospital
Parker, Colorado, United States, 80138
National Jewish Health-Northern Hematology Oncology
Thornton, Colorado, United States, 80260
SCL Health Lutheran Medical Center
Wheat Ridge, Colorado, United States, 80033
United States, Connecticut
Danbury Hospital
Danbury, Connecticut, United States, 06810
Smilow Cancer Hospital-Derby Care Center
Derby, Connecticut, United States, 06418
Smilow Cancer Hospital Care Center-Fairfield
Fairfield, Connecticut, United States, 06824
Greenwich Hospital
Greenwich, Connecticut, United States, 06830
Smilow Cancer Hospital Care Center at Greenwich
Greenwich, Connecticut, United States, 06830
Hartford Hospital
Hartford, Connecticut, United States, 06102
Smilow Cancer Hospital Care Center at Saint Francis
Hartford, Connecticut, United States, 06105
Midstate Medical Center
Meriden, Connecticut, United States, 06451
The Hospital of Central Connecticut
New Britain, Connecticut, United States, 06050
Smilow Cancer Center/Yale-New Haven Hospital
New Haven, Connecticut, United States, 06510
Yale University
New Haven, Connecticut, United States, 06520
Yale-New Haven Hospital North Haven Medical Center
North Haven, Connecticut, United States, 06473
Norwalk Hospital
Norwalk, Connecticut, United States, 06856
Smilow Cancer Hospital-Orange Care Center
Orange, Connecticut, United States, 06477
Smilow Cancer Hospital-Torrington Care Center
Torrington, Connecticut, United States, 06790
Smilow Cancer Hospital Care Center-Trumbull
Trumbull, Connecticut, United States, 06611
Smilow Cancer Hospital-Waterbury Care Center
Waterbury, Connecticut, United States, 06708
United States, Delaware
Beebe South Coastal Health Campus
Frankford, Delaware, United States, 19945
Helen F Graham Cancer Center
Newark, Delaware, United States, 19713
Medical Oncology Hematology Consultants PA
Newark, Delaware, United States, 19713
Beebe Health Campus
Rehoboth Beach, Delaware, United States, 19971
TidalHealth Nanticoke / Allen Cancer Center
Seaford, Delaware, United States, 19973
United States, District of Columbia
Sibley Memorial Hospital
Washington, District of Columbia, United States, 20016
United States, Florida
AdventHealth Altamonte
Altamonte Springs, Florida, United States, 32701
AdventHealth Celebration
Celebration, Florida, United States, 34747
Morton Plant Hospital
Clearwater, Florida, United States, 33756
UM Sylvester Comprehensive Cancer Center at Coral Gables
Coral Gables, Florida, United States, 33146
Halifax Health Medical Center-Centers for Oncology
Daytona Beach, Florida, United States, 32114
UM Sylvester Comprehensive Cancer Center at Deerfield Beach
Deerfield Beach, Florida, United States, 33442
University of Florida Health Science Center - Gainesville
Gainesville, Florida, United States, 32610
Baptist MD Anderson Cancer Center
Jacksonville, Florida, United States, 32207
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, United States, 33136
UM Sylvester Comprehensive Cancer Center at Kendall
Miami, Florida, United States, 33176
Mount Sinai Medical Center
Miami Beach, Florida, United States, 33140
AdventHealth Orlando
Orlando, Florida, United States, 32803
Orlando Health Cancer Institute
Orlando, Florida, United States, 32806
Sacred Heart Hospital
Pensacola, Florida, United States, 32504
UM Sylvester Comprehensive Cancer Center at Plantation
Plantation, Florida, United States, 33324
Tallahassee Memorial HealthCare
Tallahassee, Florida, United States, 32308
Saint Joseph's Hospital/Children's Hospital-Tampa
Tampa, Florida, United States, 33607
Cleveland Clinic-Weston
Weston, Florida, United States, 33331
United States, Georgia
Phoebe Putney Memorial Hospital
Albany, Georgia, United States, 31701
Emory University Hospital Midtown
Atlanta, Georgia, United States, 30308
Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia, United States, 30322
Emory Saint Joseph's Hospital
Atlanta, Georgia, United States, 30342
Northside Hospital
Atlanta, Georgia, United States, 30342
Augusta Oncology Associates PC-D'Antignac
Augusta, Georgia, United States, 30901
Augusta Oncology Associates PC-Wheeler
Augusta, Georgia, United States, 30909
Dekalb Medical Center
Decatur, Georgia, United States, 30033
Northside Hospital - Duluth
Duluth, Georgia, United States, 30096
Northside Hospital - Gwinnett
Lawrenceville, Georgia, United States, 30046
CTCA at Southeastern Regional Medical Center
Newnan, Georgia, United States, 30265
Memorial Health University Medical Center
Savannah, Georgia, United States, 31404
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
Savannah, Georgia, United States, 31405
Suburban Hematology Oncology Associates - Snellville
Snellville, Georgia, United States, 30078
South Georgia Medical Center/Pearlman Cancer Center
Valdosta, Georgia, United States, 31602
United States, Hawaii
Hawaii Cancer Care - Savio
'Aiea, Hawaii, United States, 96701
Hawaii Cancer Care Inc - Waterfront Plaza
Honolulu, Hawaii, United States, 96813
Queen's Cancer Cenrer - POB I
Honolulu, Hawaii, United States, 96813
Queen's Medical Center
Honolulu, Hawaii, United States, 96813
Queen's Cancer Center - Kuakini
Honolulu, Hawaii, United States, 96817
Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, United States, 96826
United States, Idaho
Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho, United States, 83706
Saint Luke's Cancer Institute - Boise
Boise, Idaho, United States, 83712
Saint Alphonsus Cancer Care Center-Caldwell
Caldwell, Idaho, United States, 83605
Kootenai Health - Coeur d'Alene
Coeur d'Alene, Idaho, United States, 83814
Walter Knox Memorial Hospital
Emmett, Idaho, United States, 83617
Saint Luke's Cancer Institute - Fruitland
Fruitland, Idaho, United States, 83619
Idaho Urologic Institute-Meridian
Meridian, Idaho, United States, 83642
Saint Luke's Cancer Institute - Meridian
Meridian, Idaho, United States, 83642
Saint Alphonsus Medical Center-Nampa
Nampa, Idaho, United States, 83686
Saint Luke's Cancer Institute - Nampa
Nampa, Idaho, United States, 83686
Kootenai Clinic Cancer Services - Post Falls
Post Falls, Idaho, United States, 83854
Kootenai Cancer Clinic
Sandpoint, Idaho, United States, 83864
Saint Luke's Cancer Institute - Twin Falls
Twin Falls, Idaho, United States, 83301
United States, Illinois
Northwest Community Hospital
Arlington Heights, Illinois, United States, 60005
Rush - Copley Medical Center
Aurora, Illinois, United States, 60504
Mac Neal Hospital
Berwyn, Illinois, United States, 60402
Illinois CancerCare-Bloomington
Bloomington, Illinois, United States, 61704
Illinois CancerCare-Canton
Canton, Illinois, United States, 61520
SIH Cancer Institute
Carterville, Illinois, United States, 62918
Illinois CancerCare-Carthage
Carthage, Illinois, United States, 62321
Centralia Oncology Clinic
Centralia, Illinois, United States, 62801
Mount Sinai Hospital Medical Center
Chicago, Illinois, United States, 60608
Northwestern University
Chicago, Illinois, United States, 60611
Rush University Medical Center
Chicago, Illinois, United States, 60612
University of Illinois
Chicago, Illinois, United States, 60612
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, United States, 60637
Weiss Memorial Hospital
Chicago, Illinois, United States, 60640
Carle on Vermilion
Danville, Illinois, United States, 61832
Northwestern Medicine Cancer Center Kishwaukee
DeKalb, Illinois, United States, 60115
Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois, United States, 62526
Decatur Memorial Hospital
Decatur, Illinois, United States, 62526
Carle Physician Group-Effingham
Effingham, Illinois, United States, 62401
Crossroads Cancer Center
Effingham, Illinois, United States, 62401
Illinois CancerCare-Eureka
Eureka, Illinois, United States, 61530
NorthShore University HealthSystem-Evanston Hospital
Evanston, Illinois, United States, 60201
Freeport Memorial Hospital/Leonard C Ferguson Cancer Center
Freeport, Illinois, United States, 61032
Illinois CancerCare-Galesburg
Galesburg, Illinois, United States, 61401
Northwestern Medicine Cancer Center Delnor
Geneva, Illinois, United States, 60134
NorthShore University HealthSystem-Glenbrook Hospital
Glenview, Illinois, United States, 60026
Ingalls Memorial Hospital
Harvey, Illinois, United States, 60426
NorthShore University HealthSystem-Highland Park Hospital
Highland Park, Illinois, United States, 60035
Duly Health and Care Joliet
Joliet, Illinois, United States, 60435
Presence Saint Mary's Hospital
Kankakee, Illinois, United States, 60901
Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois, United States, 61443
Northwestern Medicine Lake Forest Hospital
Lake Forest, Illinois, United States, 60045
Illinois CancerCare-Macomb
Macomb, Illinois, United States, 61455
Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois, United States, 61938
Loyola University Medical Center
Maywood, Illinois, United States, 60153
Good Samaritan Regional Health Center
Mount Vernon, Illinois, United States, 62864
UC Comprehensive Cancer Center at Silver Cross
New Lenox, Illinois, United States, 60451
Cancer Care Center of O'Fallon
O'Fallon, Illinois, United States, 62269
University of Chicago Medicine-Orland Park
Orland Park, Illinois, United States, 60462
Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois, United States, 61350
Advocate Lutheran General Hospital
Park Ridge, Illinois, United States, 60068
Illinois CancerCare-Pekin
Pekin, Illinois, United States, 61554
Illinois CancerCare-Peoria
Peoria, Illinois, United States, 61615
Illinois CancerCare-Peru
Peru, Illinois, United States, 61354
Illinois CancerCare-Princeton
Princeton, Illinois, United States, 61356
West Suburban Medical Center
River Forest, Illinois, United States, 60305
SwedishAmerican Regional Cancer Center/ACT
Rockford, Illinois, United States, 61114
Genesis Cancer Center - Silvis
Silvis, Illinois, United States, 61282
Southern Illinois University School of Medicine
Springfield, Illinois, United States, 62702
Springfield Clinic
Springfield, Illinois, United States, 62702
Memorial Medical Center
Springfield, Illinois, United States, 62781
Carle Cancer Center
Urbana, Illinois, United States, 61801
Northwestern Medicine Cancer Center Warrenville
Warrenville, Illinois, United States, 60555
Rush-Copley Healthcare Center
Yorkville, Illinois, United States, 60560
United States, Indiana
IU Health North Hospital
Carmel, Indiana, United States, 46032
Deaconess Clinic Downtown
Evansville, Indiana, United States, 47713
Parkview Regional Medical Center
Fort Wayne, Indiana, United States, 46845
Goshen Center for Cancer Care
Goshen, Indiana, United States, 46526
Indiana University/Melvin and Bren Simon Cancer Center
Indianapolis, Indiana, United States, 46202
Sidney and Lois Eskenazi Hospital
Indianapolis, Indiana, United States, 46202
Community Cancer Center East
Indianapolis, Indiana, United States, 46219
Community Cancer Center South
Indianapolis, Indiana, United States, 46227
Franciscan Health Indianapolis
Indianapolis, Indiana, United States, 46237
Community Cancer Center North
Indianapolis, Indiana, United States, 46256
Springmill Medical Center
Indianapolis, Indiana, United States, 46290
Community Howard Regional Health
Kokomo, Indiana, United States, 46904
Franciscan Saint Elizabeth Health - Lafayette East
Lafayette, Indiana, United States, 47905
Memorial Regional Cancer Center Day Road
Mishawaka, Indiana, United States, 46545
Baptist Health Floyd
New Albany, Indiana, United States, 47150
Chancellor Center for Oncology
Newburgh, Indiana, United States, 47630
Memorial Hospital of South Bend
South Bend, Indiana, United States, 46601
Union Hospital
Terre Haute, Indiana, United States, 47804
United States, Iowa
Mary Greeley Medical Center
Ames, Iowa, United States, 50010
McFarland Clinic PC - Ames
Ames, Iowa, United States, 50010
University of Iowa Healthcare Cancer Services Quad Cities
Bettendorf, Iowa, United States, 52722
McFarland Clinic PC-Boone
Boone, Iowa, United States, 50036
Physicians' Clinic of Iowa PC
Cedar Rapids, Iowa, United States, 52402
Mercy Hospital
Cedar Rapids, Iowa, United States, 52403
Oncology Associates at Mercy Medical Center
Cedar Rapids, Iowa, United States, 52403
Medical Oncology and Hematology Associates-West Des Moines
Clive, Iowa, United States, 50325
Mercy Cancer Center-West Lakes
Clive, Iowa, United States, 50325
Greater Regional Medical Center
Creston, Iowa, United States, 50801
Genesis Medical Center - East Campus
Davenport, Iowa, United States, 52803
Genesis Cancer Care Institute
Davenport, Iowa, United States, 52804
Iowa Cancer Specialists
Davenport, Iowa, United States, 52807
Iowa Methodist Medical Center
Des Moines, Iowa, United States, 50309
Medical Oncology and Hematology Associates-Des Moines
Des Moines, Iowa, United States, 50309
Broadlawns Medical Center
Des Moines, Iowa, United States, 50314
Medical Oncology and Hematology Associates-Laurel
Des Moines, Iowa, United States, 50314
Mercy Medical Center - Des Moines
Des Moines, Iowa, United States, 50314
Iowa Lutheran Hospital
Des Moines, Iowa, United States, 50316
McFarland Clinic PC-Trinity Cancer Center
Fort Dodge, Iowa, United States, 50501
Trinity Regional Medical Center
Fort Dodge, Iowa, United States, 50501
University of Iowa/Holden Comprehensive Cancer Center
Iowa City, Iowa, United States, 52242
McFarland Clinic PC-Jefferson
Jefferson, Iowa, United States, 50129
McFarland Clinic PC-Marshalltown
Marshalltown, Iowa, United States, 50158
Methodist West Hospital
West Des Moines, Iowa, United States, 50266-7700
Mercy Medical Center-West Lakes
West Des Moines, Iowa, United States, 50266
United States, Kansas
Cancer Center of Kansas - Chanute
Chanute, Kansas, United States, 66720
Cancer Center of Kansas - Dodge City
Dodge City, Kansas, United States, 67801
Cancer Center of Kansas - Fort Scott
Fort Scott, Kansas, United States, 66701
Central Care Cancer Center - Garden City
Garden City, Kansas, United States, 67846
Central Care Cancer Center - Great Bend
Great Bend, Kansas, United States, 67530
HaysMed University of Kansas Health System
Hays, Kansas, United States, 67601
University of Kansas Cancer Center-West
Kansas City, Kansas, United States, 66112
University of Kansas Cancer Center
Kansas City, Kansas, United States, 66160
Cancer Center of Kansas-Kingman
Kingman, Kansas, United States, 67068
Lawrence Memorial Hospital
Lawrence, Kansas, United States, 66044
Kansas Institute of Medicine Cancer and Blood Center
Lenexa, Kansas, United States, 66219
Minimally Invasive Surgery Hospital
Lenexa, Kansas, United States, 66219
Cancer Center of Kansas-Liberal
Liberal, Kansas, United States, 67905
Cancer Center of Kansas - McPherson
McPherson, Kansas, United States, 67460
Cancer Center of Kansas - Newton
Newton, Kansas, United States, 67114
Olathe Health Cancer Center
Olathe, Kansas, United States, 66061
Menorah Medical Center
Overland Park, Kansas, United States, 66209
University of Kansas Cancer Center-Overland Park
Overland Park, Kansas, United States, 66210
Cancer Center of Kansas - Parsons
Parsons, Kansas, United States, 67357
Ascension Via Christi - Pittsburg
Pittsburg, Kansas, United States, 66762
Cancer Center of Kansas - Pratt
Pratt, Kansas, United States, 67124
Salina Regional Health Center
Salina, Kansas, United States, 67401
Cotton O'Neil Cancer Center / Stormont Vail Health
Topeka, Kansas, United States, 66606
University of Kansas Health System Saint Francis Campus
Topeka, Kansas, United States, 66606
Cancer Center of Kansas - Wellington
Wellington, Kansas, United States, 67152
University of Kansas Hospital-Westwood Cancer Center
Westwood, Kansas, United States, 66205
Cancer Center of Kansas-Wichita Medical Arts Tower
Wichita, Kansas, United States, 67208
Ascension Via Christi Hospitals Wichita
Wichita, Kansas, United States, 67214
Cancer Center of Kansas - Wichita
Wichita, Kansas, United States, 67214
Cancer Center of Kansas - Winfield
Winfield, Kansas, United States, 67156
United States, Kentucky
Flaget Memorial Hospital
Bardstown, Kentucky, United States, 40004
Baptist Health Corbin
Corbin, Kentucky, United States, 40701
Baptist Health Lexington
Lexington, Kentucky, United States, 40503
Saint Joseph Hospital East
Lexington, Kentucky, United States, 40509
University of Kentucky/Markey Cancer Center
Lexington, Kentucky, United States, 40536
Saint Joseph London
London, Kentucky, United States, 40741
Baptist Health Louisville
Louisville, Kentucky, United States, 40207
United States, Louisiana
Christus Saint Frances Cabrini Hospital
Alexandria, Louisiana, United States, 71301
LSU Health Baton Rouge-North Clinic
Baton Rouge, Louisiana, United States, 70805
Hematology/Oncology Clinic PLLC
Baton Rouge, Louisiana, United States, 70809
Louisiana Hematology Oncology Associates LLC
Baton Rouge, Louisiana, United States, 70809
Mary Bird Perkins Cancer Center
Baton Rouge, Louisiana, United States, 70809
Ochsner Health Center-Summa
Baton Rouge, Louisiana, United States, 70809
Our Lady of the Lake Physicians Group - Medical Oncology
Baton Rouge, Louisiana, United States, 70809
Medical Center of Baton Rouge
Baton Rouge, Louisiana, United States, 70816
Woman's Hospital
Baton Rouge, Louisiana, United States, 70817
Ochsner High Grove
Baton Rouge, Louisiana, United States, 70836
Northshore Oncology Associates-Covington
Covington, Louisiana, United States, 70433
Ochsner Hematology Oncology North Shore - Covington (West Region)
Covington, Louisiana, United States, 70433
Oncology Center of The South Incorporated
Houma, Louisiana, United States, 70360
Terrebonne General Medical Center
Houma, Louisiana, United States, 70360
Ochsner Medical Center Kenner
Kenner, Louisiana, United States, 70065
CHRISTUS Saint Patrick Hospital
Lake Charles, Louisiana, United States, 70601
East Jefferson General Hospital
Metairie, Louisiana, United States, 70006
University Medical Center New Orleans
New Orleans, Louisiana, United States, 70112
Ochsner Medical Center Jefferson
New Orleans, Louisiana, United States, 70121
LSU Health Sciences Center at Shreveport
Shreveport, Louisiana, United States, 71103
United States, Maine
Harold Alfond Center for Cancer Care
Augusta, Maine, United States, 04330
Eastern Maine Medical Center
Bangor, Maine, United States, 04401
Waldo County General Hospital
Belfast, Maine, United States, 04915
MaineHealth/SMHC Cancer Care and Blood Disorders-Biddeford
Biddeford, Maine, United States, 04005
Lafayette Family Cancer Center-EMMC
Brewer, Maine, United States, 04412
Maine Center for Cancer Medicine-Kennebunk
Kennebunk, Maine, United States, 04043
Stephens Memorial Hospital
Norway, Maine, United States, 04268
Penobscot Bay Medical Center
Rockport, Maine, United States, 04856
MaineHealth/SMHC Cancer Care and Blood Disorders-Sanford
Sanford, Maine, United States, 04073
Maine Center for Cancer Medicine-Scarborough
Scarborough, Maine, United States, 04074
Maine Medical Partners - South Portland
South Portland, Maine, United States, 04106
Maine Center for Cancer Medicine-Topsham
Topsham, Maine, United States, 04086
York Hospital
York, Maine, United States, 03909
United States, Maryland
Anne Arundel Medical Center
Annapolis, Maryland, United States, 21401
University of Maryland/Greenebaum Cancer Center
Baltimore, Maryland, United States, 21201
Mercy Medical Center
Baltimore, Maryland, United States, 21202
Greater Baltimore Medical Center
Baltimore, Maryland, United States, 21204
Saint Agnes Hospital
Baltimore, Maryland, United States, 21229
MedStar Franklin Square Medical Center/Weinberg Cancer Institute
Baltimore, Maryland, United States, 21237
MedStar Good Samaritan Hospital
Baltimore, Maryland, United States, 21239
Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, United States, 21287
UM Upper Chesapeake Medical Center
Bel Air, Maryland, United States, 21014
Frederick Memorial Hospital
Frederick, Maryland, United States, 21701
FMH James M Stockman Cancer Institute
Frederick, Maryland, United States, 21702
TidalHealth Richard A Henson Cancer Institute
Ocean Pines, Maryland, United States, 21811
TidalHealth Peninsula Regional
Salisbury, Maryland, United States, 21801
UM Saint Joseph Medical Center
Towson, Maryland, United States, 21204
United States, Massachusetts
Boston Medical Center
Boston, Massachusetts, United States, 02118
Lahey Hospital and Medical Center
Burlington, Massachusetts, United States, 01805
Lowell General Hospital
Lowell, Massachusetts, United States, 01854
Baystate Medical Center
Springfield, Massachusetts, United States, 01199
Winchester Hospital
Winchester, Massachusetts, United States, 01890
United States, Michigan
Saint Joseph Mercy Hospital
Ann Arbor, Michigan, United States, 48106
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, United States, 48109
Bronson Battle Creek
Battle Creek, Michigan, United States, 49017
McLaren Cancer Institute-Bay City
Bay City, Michigan, United States, 48706
IHA Hematology Oncology Consultants-Brighton
Brighton, Michigan, United States, 48114
Saint Joseph Mercy Brighton
Brighton, Michigan, United States, 48114
Henry Ford Cancer Institute-Downriver
Brownstown, Michigan, United States, 48183
IHA Hematology Oncology Consultants-Canton
Canton, Michigan, United States, 48188
Saint Joseph Mercy Canton
Canton, Michigan, United States, 48188
Caro Cancer Center
Caro, Michigan, United States, 48723
IHA Hematology Oncology Consultants-Chelsea
Chelsea, Michigan, United States, 48118
Saint Joseph Mercy Chelsea
Chelsea, Michigan, United States, 48118
Hematology Oncology Consultants-Clarkston
Clarkston, Michigan, United States, 48346
McLaren Cancer Institute-Clarkston
Clarkston, Michigan, United States, 48346
Newland Medical Associates-Clarkston
Clarkston, Michigan, United States, 48346
Henry Ford Macomb Hospital-Clinton Township
Clinton Township, Michigan, United States, 48038
Beaumont Hospital - Dearborn
Dearborn, Michigan, United States, 48124
Henry Ford Medical Center-Fairlane
Dearborn, Michigan, United States, 48126
Wayne State University/Karmanos Cancer Institute
Detroit, Michigan, United States, 48201
Henry Ford Hospital
Detroit, Michigan, United States, 48202
Ascension Saint John Hospital
Detroit, Michigan, United States, 48236
Great Lakes Cancer Management Specialists-Doctors Park
East China Township, Michigan, United States, 48054
Michigan State University Clinical Center
East Lansing, Michigan, United States, 48824-7016
Weisberg Cancer Treatment Center
Farmington Hills, Michigan, United States, 48334
Beaumont Hospital - Farmington Hills
Farmington Hills, Michigan, United States, 48336
Genesee Cancer and Blood Disease Treatment Center
Flint, Michigan, United States, 48503
Genesee Hematology Oncology PC
Flint, Michigan, United States, 48503
Genesys Hurley Cancer Institute
Flint, Michigan, United States, 48503
Hurley Medical Center
Flint, Michigan, United States, 48503
McLaren Cancer Institute-Flint
Flint, Michigan, United States, 48532
Singh and Arora Hematology Oncology PC
Flint, Michigan, United States, 48532
Mercy Health Saint Mary's
Grand Rapids, Michigan, United States, 49503
Spectrum Health at Butterworth Campus
Grand Rapids, Michigan, United States, 49503
Academic Hematology Oncology Specialists
Grosse Pointe Woods, Michigan, United States, 48236
Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
Grosse Pointe Woods, Michigan, United States, 48236
Bronson Methodist Hospital
Kalamazoo, Michigan, United States, 49007
West Michigan Cancer Center
Kalamazoo, Michigan, United States, 49007
Karmanos Cancer Institute at McLaren Greater Lansing
Lansing, Michigan, United States, 48910
Mid-Michigan Physicians-Lansing
Lansing, Michigan, United States, 48912
Sparrow Hospital
Lansing, Michigan, United States, 48912
McLaren Cancer Institute-Lapeer Region
Lapeer, Michigan, United States, 48446
Saint Mary Mercy Hospital
Livonia, Michigan, United States, 48154
Great Lakes Cancer Management Specialists-Macomb Medical Campus
Macomb, Michigan, United States, 48044
Saint Mary's Oncology/Hematology Associates of Marlette
Marlette, Michigan, United States, 48453
UP Health System Marquette
Marquette, Michigan, United States, 49855
Mid-Michigan Medical Center - Midland
Midland, Michigan, United States, 48670
Monroe Cancer Center
Monroe, Michigan, United States, 48162
McLaren Cancer Institute-Macomb
Mount Clemens, Michigan, United States, 48043
McLaren Cancer Institute-Central Michigan
Mount Pleasant, Michigan, United States, 48858
Mercy Health Mercy Campus
Muskegon, Michigan, United States, 49444
Ascension Providence Hospitals - Novi
Novi, Michigan, United States, 48374
Henry Ford Medical Center-Columbus
Novi, Michigan, United States, 48377
McLaren Cancer Institute-Northern Michigan
Petoskey, Michigan, United States, 49770
21st Century Oncology-Pontiac
Pontiac, Michigan, United States, 48341
Hope Cancer Center
Pontiac, Michigan, United States, 48341
Newland Medical Associates-Pontiac
Pontiac, Michigan, United States, 48341
Saint Joseph Mercy Oakland
Pontiac, Michigan, United States, 48341
McLaren-Port Huron
Port Huron, Michigan, United States, 48060
Spectrum Health Reed City Hospital
Reed City, Michigan, United States, 49677
Great Lakes Cancer Management Specialists-Rochester Hills
Rochester Hills, Michigan, United States, 48309
William Beaumont Hospital-Royal Oak
Royal Oak, Michigan, United States, 48073
Ascension Saint Mary's Hospital
Saginaw, Michigan, United States, 48601
Oncology Hematology Associates of Saginaw Valley PC
Saginaw, Michigan, United States, 48604
Marie Yeager Cancer Center
Saint Joseph, Michigan, United States, 49085
Ascension Providence Hospitals - Southfield
Southfield, Michigan, United States, 48075
Munson Medical Center
Traverse City, Michigan, United States, 49684
William Beaumont Hospital - Troy
Troy, Michigan, United States, 48085
Great Lakes Cancer Management Specialists-Macomb Professional Building
Warren, Michigan, United States, 48093
Saint John Macomb-Oakland Hospital
Warren, Michigan, United States, 48093
Henry Ford West Bloomfield Hospital
West Bloomfield, Michigan, United States, 48322
Saint Mary's Oncology/Hematology Associates of West Branch
West Branch, Michigan, United States, 48661
Metro Health Hospital
Wyoming, Michigan, United States, 49519
IHA Hematology Oncology Consultants-Ann Arbor
Ypsilanti, Michigan, United States, 48197
United States, Minnesota
Sanford Joe Lueken Cancer Center
Bemidji, Minnesota, United States, 56601
Essentia Health Saint Joseph's Medical Center
Brainerd, Minnesota, United States, 56401
Fairview Ridges Hospital
Burnsville, Minnesota, United States, 55337
Minnesota Oncology - Burnsville
Burnsville, Minnesota, United States, 55337
Mercy Hospital
Coon Rapids, Minnesota, United States, 55433
Essentia Health - Deer River Clinic
Deer River, Minnesota, United States, 56636
Essentia Health Cancer Center
Duluth, Minnesota, United States, 55805
Essentia Health Saint Mary's Medical Center
Duluth, Minnesota, United States, 55805
Miller-Dwan Hospital
Duluth, Minnesota, United States, 55805
Fairview Southdale Hospital
Edina, Minnesota, United States, 55435
Unity Hospital
Fridley, Minnesota, United States, 55432
Essentia Health Hibbing Clinic
Hibbing, Minnesota, United States, 55746
Fairview Clinics and Surgery Center Maple Grove
Maple Grove, Minnesota, United States, 55369
Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota, United States, 55109
Saint John's Hospital - Healtheast
Maplewood, Minnesota, United States, 55109
Abbott-Northwestern Hospital
Minneapolis, Minnesota, United States, 55407
Hennepin County Medical Center
Minneapolis, Minnesota, United States, 55415
Health Partners Inc
Minneapolis, Minnesota, United States, 55454
New Ulm Medical Center
New Ulm, Minnesota, United States, 56073
North Memorial Medical Health Center
Robbinsdale, Minnesota, United States, 55422
Coborn Cancer Center at Saint Cloud Hospital
Saint Cloud, Minnesota, United States, 56303
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota, United States, 55416
Regions Hospital
Saint Paul, Minnesota, United States, 55101
United Hospital
Saint Paul, Minnesota, United States, 55102
Essentia Health Sandstone
Sandstone, Minnesota, United States, 55072
Saint Francis Regional Medical Center
Shakopee, Minnesota, United States, 55379
Lakeview Hospital
Stillwater, Minnesota, United States, 55082
Essentia Health Virginia Clinic
Virginia, Minnesota, United States, 55792
Ridgeview Medical Center
Waconia, Minnesota, United States, 55387
Rice Memorial Hospital
Willmar, Minnesota, United States, 56201
Minnesota Oncology Hematology PA-Woodbury
Woodbury, Minnesota, United States, 55125
Fairview Lakes Medical Center
Wyoming, Minnesota, United States, 55092
United States, Mississippi
Baptist Memorial Hospital and Cancer Center-Golden Triangle
Columbus, Mississippi, United States, 39705
Baptist Cancer Center-Grenada
Grenada, Mississippi, United States, 38901
Baptist Memorial Hospital and Cancer Center-Union County
New Albany, Mississippi, United States, 38652
Baptist Memorial Hospital and Cancer Center-Oxford
Oxford, Mississippi, United States, 38655
Singing River Hospital
Pascagoula, Mississippi, United States, 39581
Baptist Memorial Hospital and Cancer Center-Desoto
Southhaven, Mississippi, United States, 38671
United States, Missouri
Saint Louis Cancer and Breast Institute-Ballwin
Ballwin, Missouri, United States, 63011
Central Care Cancer Center - Bolivar
Bolivar, Missouri, United States, 65613
Saint Francis Medical Center
Cape Girardeau, Missouri, United States, 63703
Southeast Cancer Center
Cape Girardeau, Missouri, United States, 63703
Centerpoint Medical Center LLC
Independence, Missouri, United States, 64057
Capital Region Southwest Campus
Jefferson City, Missouri, United States, 65109
Freeman Health System
Joplin, Missouri, United States, 64804
Truman Medical Centers
Kansas City, Missouri, United States, 64108
Research Medical Center
Kansas City, Missouri, United States, 64132
University of Kansas Cancer Center - North
Kansas City, Missouri, United States, 64154
University of Kansas Cancer Center at North Kansas City Hospital
North Kansas City, Missouri, United States, 64116
Heartland Regional Medical Center
Saint Joseph, Missouri, United States, 64506
Saint Louis Cancer and Breast Institute-South City
Saint Louis, Missouri, United States, 63109
Missouri Baptist Medical Center
Saint Louis, Missouri, United States, 63131
Mercy Hospital Saint Louis
Saint Louis, Missouri, United States, 63141
Mercy Hospital Springfield
Springfield, Missouri, United States, 65804
CoxHealth South Hospital
Springfield, Missouri, United States, 65807
United States, Montana
Community Hospital of Anaconda
Anaconda, Montana, United States, 59711
Billings Clinic Cancer Center
Billings, Montana, United States, 59101
Bozeman Deaconess Hospital
Bozeman, Montana, United States, 59715
Saint James Community Hospital and Cancer Treatment Center
Butte, Montana, United States, 59701
Benefis Healthcare- Sletten Cancer Institute
Great Falls, Montana, United States, 59405
Great Falls Clinic
Great Falls, Montana, United States, 59405
Saint Peter's Community Hospital
Helena, Montana, United States, 59601
Kalispell Regional Medical Center
Kalispell, Montana, United States, 59901
Community Medical Hospital
Missoula, Montana, United States, 59804
United States, Nebraska
CHI Health Saint Francis
Grand Island, Nebraska, United States, 68803
CHI Health Good Samaritan
Kearney, Nebraska, United States, 68847
Nebraska Methodist Hospital
Omaha, Nebraska, United States, 68114
Alegent Health Immanuel Medical Center
Omaha, Nebraska, United States, 68122
Alegent Health Bergan Mercy Medical Center
Omaha, Nebraska, United States, 68124
Alegent Health Lakeside Hospital
Omaha, Nebraska, United States, 68130
University of Nebraska Medical Center
Omaha, Nebraska, United States, 68198
United States, Nevada
OptumCare Cancer Care at Seven Hills
Henderson, Nevada, United States, 89052
OptumCare Cancer Care at Charleston
Las Vegas, Nevada, United States, 89102
OptumCare Cancer Care at MountainView
Las Vegas, Nevada, United States, 89128
OptumCare Cancer Care at Fort Apache
Las Vegas, Nevada, United States, 89148
Renown Regional Medical Center
Reno, Nevada, United States, 89502
Saint Mary's Regional Medical Center
Reno, Nevada, United States, 89503
United States, New Hampshire
New Hampshire Oncology Hematology PA-Concord
Concord, New Hampshire, United States, 03301
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, United States, 03756
Norris Cotton Cancer Center-Manchester
Manchester, New Hampshire, United States, 03102
Solinsky Center for Cancer Care
Manchester, New Hampshire, United States, 03103
Saint Joseph Hospital
Nashua, New Hampshire, United States, 03060
Norris Cotton Cancer Center-Nashua
Nashua, New Hampshire, United States, 03063
United States, New Jersey
Ocean Medical Center
Brick, New Jersey, United States, 08724
Trinitas Hospital and Comprehensive Cancer Center - Williamson Street Campus
Elizabeth, New Jersey, United States, 07207
Hackensack University Medical Center
Hackensack, New Jersey, United States, 07601
The Cancer Institute of New Jersey Hamilton
Hamilton, New Jersey, United States, 08690
Saint Barnabas Medical Center
Livingston, New Jersey, United States, 07039
Monmouth Medical Center
Long Branch, New Jersey, United States, 07740
Southern Ocean County Medical Center
Manahawkin, New Jersey, United States, 08050
Virtua Memorial
Mount Holly, New Jersey, United States, 08060
Jersey Shore Medical Center
Neptune, New Jersey, United States, 07753
Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, United States, 08903
Newark Beth Israel Medical Center
Newark, New Jersey, United States, 07112
The Valley Hospital-Luckow Pavilion
Paramus, New Jersey, United States, 07652
Riverview Medical Center/Booker Cancer Center
Red Bank, New Jersey, United States, 07701
Valley Hospital
Ridgewood, New Jersey, United States, 07450
Robert Wood Johnson University Hospital Somerset
Somerville, New Jersey, United States, 08876
Sparta Cancer Treatment Center
Sparta, New Jersey, United States, 07871
MD Anderson Cancer Center at Cooper-Voorhees
Voorhees, New Jersey, United States, 08043
Virtua Voorhees
Voorhees, New Jersey, United States, 08043
Valley Health System-Hematology/Oncology
Westwood, New Jersey, United States, 07675
United States, New Mexico
Lovelace Medical Center-Saint Joseph Square
Albuquerque, New Mexico, United States, 87102
University of New Mexico Cancer Center
Albuquerque, New Mexico, United States, 87102
New Mexico Oncology Hematology Consultants
Albuquerque, New Mexico, United States, 87109
Presbyterian Kaseman Hospital
Albuquerque, New Mexico, United States, 87110
Memorial Medical Center - Las Cruces
Las Cruces, New Mexico, United States, 88011
Presbyterian Rust Medical Center/Jorgensen Cancer Center
Rio Rancho, New Mexico, United States, 87124
Christus Saint Vincent Regional Cancer Center
Santa Fe, New Mexico, United States, 87505
United States, New York
Montefiore Medical Center-Einstein Campus
Bronx, New York, United States, 10461
Montefiore Medical Center-Weiler Hospital
Bronx, New York, United States, 10461
Montefiore Medical Center - Moses Campus
Bronx, New York, United States, 10467
New York-Presbyterian/Brooklyn Methodist Hospital
Brooklyn, New York, United States, 11215
Roswell Park Cancer Institute
Buffalo, New York, United States, 14263
Arnot Ogden Medical Center/Falck Cancer Center
Elmira, New York, United States, 14905
Garnet Health Medical Center
Middletown, New York, United States, 10940
NYU Winthrop Hospital
Mineola, New York, United States, 11501
Mount Sinai Union Square
New York, New York, United States, 10003
Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York, New York, United States, 10016
Mount Sinai West
New York, New York, United States, 10019
Mount Sinai Hospital
New York, New York, United States, 10029
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
New York, New York, United States, 10032
NYP/Weill Cornell Medical Center
New York, New York, United States, 10065
University of Rochester
Rochester, New York, United States, 14642
Staten Island University Hospital
Staten Island, New York, United States, 10305
Stony Brook University Medical Center
Stony Brook, New York, United States, 11794
State University of New York Upstate Medical University
Syracuse, New York, United States, 13210
Dickstein Cancer Treatment Center
White Plains, New York, United States, 10601
United States, North Carolina
Atrium Health Stanly/LCI-Albemarle
Albemarle, North Carolina, United States, 28002
Randolph Hospital
Asheboro, North Carolina, United States, 27203
Mission Hospital
Asheville, North Carolina, United States, 28801
Messino Cancer Centers
Asheville, North Carolina, United States, 28806
Hope Women's Cancer Centers-Asheville
Asheville, North Carolina, United States, 28816
Cone Health Cancer Center at Alamance Regional
Burlington, North Carolina, United States, 27215
UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, United States, 27599
Carolinas Medical Center/Levine Cancer Institute
Charlotte, North Carolina, United States, 28203
Novant Health Presbyterian Medical Center
Charlotte, North Carolina, United States, 28204
Oncology Specialists of Charlotte
Charlotte, North Carolina, United States, 28207
Atrium Health Pineville/LCI-Pineville
Charlotte, North Carolina, United States, 28210
Southeastern Medical Oncology Center-Clinton
Clinton, North Carolina, United States, 28328
Atrium Health Cabarrus/LCI-Concord
Concord, North Carolina, United States, 28025
Duke University Medical Center
Durham, North Carolina, United States, 27710
Southeastern Medical Oncology Center-Goldsboro
Goldsboro, North Carolina, United States, 27534
Cone Health Cancer Center
Greensboro, North Carolina, United States, 27403
Margaret R Pardee Memorial Hospital
Hendersonville, North Carolina, United States, 28791
Novant Health Cancer Institute - Huntersville
Huntersville, North Carolina, United States, 28078
Southern Oncology Specialists-Huntersville
Huntersville, North Carolina, United States, 28078
Southeastern Medical Oncology Center-Jacksonville
Jacksonville, North Carolina, United States, 28546
Vidant Oncology-Kenansville
Kenansville, North Carolina, United States, 28349
Novant Health Cancer Institute - Kernersville
Kernersville, North Carolina, United States, 27284
Vidant Oncology-Kinston
Kinston, North Carolina, United States, 28501
Novant Health Cancer Specialists-Matthews
Matthews, North Carolina, United States, 28105
Cone Heath Cancer Center at Mebane
Mebane, North Carolina, United States, 27302
Novant Health Cancer Institute - Mooresville
Mooresville, North Carolina, United States, 28117
Novant Health Cancer Institute - Mount Airy
Mount Airy, North Carolina, United States, 27030
FirstHealth of the Carolinas-Moore Regional Hospital
Pinehurst, North Carolina, United States, 28374
Annie Penn Memorial Hospital
Reidsville, North Carolina, United States, 27320
Vidant Oncology-Richlands
Richlands, North Carolina, United States, 28574
Novant Health Cancer Institute - Statesville
Statesville, North Carolina, United States, 28625
Novant Health Cancer Institute - Thomasville
Thomasville, North Carolina, United States, 27360
Novant Health Cancer Institute - Wilkesboro
Wilkesboro, North Carolina, United States, 28659
Novant Health Forsyth Medical Center
Winston-Salem, North Carolina, United States, 27103
Novant Health Oncology Specialists
Winston-Salem, North Carolina, United States, 27103
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States, 27157
United States, North Dakota
Sanford Bismarck Medical Center
Bismarck, North Dakota, United States, 58501
Essentia Health Cancer Center-South University Clinic
Fargo, North Dakota, United States, 58103
Sanford Broadway Medical Center
Fargo, North Dakota, United States, 58122
Sanford Roger Maris Cancer Center
Fargo, North Dakota, United States, 58122
United States, Ohio
Summa Health System - Akron Campus
Akron, Ohio, United States, 44304
Cleveland Clinic Cancer Center Beachwood
Beachwood, Ohio, United States, 44122
UHHS-Chagrin Highlands Medical Center
Beachwood, Ohio, United States, 44122
Indu and Raj Soin Medical Center
Beavercreek, Ohio, United States, 45431
Strecker Cancer Center-Belpre
Belpre, Ohio, United States, 45714
Cleveland Clinic Mercy Hospital
Canton, Ohio, United States, 44708
Aultman Health Foundation
Canton, Ohio, United States, 44710
Dayton Physicians LLC-Miami Valley South
Centerville, Ohio, United States, 45459
Geauga Hospital
Chardon, Ohio, United States, 44024
Adena Regional Medical Center
Chillicothe, Ohio, United States, 45601
The Christ Hospital
Cincinnati, Ohio, United States, 45219
Good Samaritan Hospital - Cincinnati
Cincinnati, Ohio, United States, 45220
Case Western Reserve University
Cleveland, Ohio, United States, 44106
MetroHealth Medical Center
Cleveland, Ohio, United States, 44109
Cleveland Clinic Cancer Center/Fairview Hospital
Cleveland, Ohio, United States, 44111
Cleveland Clinic Foundation
Cleveland, Ohio, United States, 44195
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States, 43210
Mount Carmel East Hospital
Columbus, Ohio, United States, 43213
Columbus Oncology and Hematology Associates Inc
Columbus, Ohio, United States, 43214
Riverside Methodist Hospital
Columbus, Ohio, United States, 43214
Grant Medical Center
Columbus, Ohio, United States, 43215
The Mark H Zangmeister Center
Columbus, Ohio, United States, 43219
Mount Carmel Health Center West
Columbus, Ohio, United States, 43222
Doctors Hospital
Columbus, Ohio, United States, 43228
Delaware Health Center-Grady Cancer Center
Delaware, Ohio, United States, 43015
Grady Memorial Hospital
Delaware, Ohio, United States, 43015
Mercy Cancer Center-Elyria
Elyria, Ohio, United States, 44035
Dayton Physicians LLC-Atrium
Franklin, Ohio, United States, 45005
Cleveland Clinic Cancer Center Independence
Independence, Ohio, United States, 44131
Kettering Medical Center
Kettering, Ohio, United States, 45429
Saint Rita's Medical Center
Lima, Ohio, United States, 45801
OhioHealth Mansfield Hospital
Mansfield, Ohio, United States, 44903
Cleveland Clinic Cancer Center Mansfield
Mansfield, Ohio, United States, 44906
Marietta Memorial Hospital
Marietta, Ohio, United States, 45750
OhioHealth Marion General Hospital
Marion, Ohio, United States, 43302
Hillcrest Hospital Cancer Center
Mayfield Heights, Ohio, United States, 44124
UH Seidman Cancer Center at Lake Health Mentor Campus
Mentor, Ohio, United States, 44060
UH Seidman Cancer Center at Southwest General Hospital
Middleburg Heights, Ohio, United States, 44130
Knox Community Hospital
Mount Vernon, Ohio, United States, 43050
Licking Memorial Hospital
Newark, Ohio, United States, 43055
University Hospitals Parma Medical Center
Parma, Ohio, United States, 44129
Mercy Health Perrysburg Cancer Center
Perrysburg, Ohio, United States, 43551
Southern Ohio Medical Center
Portsmouth, Ohio, United States, 45662
North Coast Cancer Care
Sandusky, Ohio, United States, 44870
UH Seidman Cancer Center at Firelands Regional Medical Center
Sandusky, Ohio, United States, 44870
Springfield Regional Medical Center
Springfield, Ohio, United States, 45505
Trinity's Tony Teramana Cancer Center
Steubenville, Ohio, United States, 43952
Cleveland Clinic Cancer Center Strongsville
Strongsville, Ohio, United States, 44136
ProMedica Flower Hospital
Sylvania, Ohio, United States, 43560
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital
Toledo, Ohio, United States, 43606
Mercy Health - Saint Anne Hospital
Toledo, Ohio, United States, 43623
Toledo Clinic Cancer Centers-Toledo
Toledo, Ohio, United States, 43623
University Hospitals Sharon Health Center
Wadsworth, Ohio, United States, 44281
South Pointe Hospital
Warrensville Heights, Ohio, United States, 44122
Saint Ann's Hospital
Westerville, Ohio, United States, 43081
UH Seidman Cancer Center at Saint John Medical Center
Westlake, Ohio, United States, 44145
UHHS-Westlake Medical Center
Westlake, Ohio, United States, 44145
Cleveland Clinic Wooster Family Health and Surgery Center
Wooster, Ohio, United States, 44691
Genesis Healthcare System Cancer Care Center
Zanesville, Ohio, United States, 43701
United States, Oklahoma
Cancer Centers of Southwest Oklahoma Research
Lawton, Oklahoma, United States, 73505
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, United States, 73104
Mercy Hospital Oklahoma City
Oklahoma City, Oklahoma, United States, 73120
Integris Cancer Institute of Oklahoma
Oklahoma City, Oklahoma, United States, 73142
Cancer Treatment Centers of America
Tulsa, Oklahoma, United States, 74133
Oklahoma Cancer Specialists and Research Institute-Tulsa
Tulsa, Oklahoma, United States, 74146
United States, Oregon
Saint Alphonsus Medical Center-Baker City
Baker City, Oregon, United States, 97814
Providence Cancer Institute Clackamas Clinic
Clackamas, Oregon, United States, 97015
Good Samaritan Hospital
Corvallis, Oregon, United States, 97330
Three Rivers Community Hospital
Grants Pass, Oregon, United States, 97527
Legacy Mount Hood Medical Center
Gresham, Oregon, United States, 97030
Rogue Valley Medical Center
Medford, Oregon, United States, 97504
Providence Newberg Medical Center
Newberg, Oregon, United States, 97132
Saint Alphonsus Medical Center-Ontario
Ontario, Oregon, United States, 97914
Legacy Good Samaritan Hospital and Medical Center
Portland, Oregon, United States, 97210
Providence Portland Medical Center
Portland, Oregon, United States, 97213
Providence Saint Vincent Medical Center
Portland, Oregon, United States, 97225
Kaiser Permanente Northwest
Portland, Oregon, United States, 97227
Oregon Health and Science University
Portland, Oregon, United States, 97239
Legacy Meridian Park Hospital
Tualatin, Oregon, United States, 97062
United States, Pennsylvania
Jefferson Abington Hospital
Abington, Pennsylvania, United States, 19001
Lehigh Valley Hospital-Cedar Crest
Allentown, Pennsylvania, United States, 18103
Lehigh Valley Hospital - Muhlenberg
Bethlehem, Pennsylvania, United States, 18017
Bryn Mawr Hospital
Bryn Mawr, Pennsylvania, United States, 19010
Doylestown Hospital
Doylestown, Pennsylvania, United States, 18901
Saint Vincent Hospital
Erie, Pennsylvania, United States, 16544
UPMC Pinnacle Cancer Center/Community Osteopathic Campus
Harrisburg, Pennsylvania, United States, 17109
Jefferson Hospital
Jefferson Hills, Pennsylvania, United States, 15025
Riddle Memorial Hospital
Media, Pennsylvania, United States, 19063
Forbes Hospital
Monroeville, Pennsylvania, United States, 15146
Paoli Memorial Hospital
Paoli, Pennsylvania, United States, 19301
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, United States, 19107
Fox Chase Cancer Center
Philadelphia, Pennsylvania, United States, 19111
Jefferson Torresdale Hospital
Philadelphia, Pennsylvania, United States, 19114
Eastern Regional Medical Center
Philadelphia, Pennsylvania, United States, 19124
Allegheny General Hospital
Pittsburgh, Pennsylvania, United States, 15212
West Penn Hospital
Pittsburgh, Pennsylvania, United States, 15224
University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, United States, 15232
Chester County Hospital
West Chester, Pennsylvania, United States, 19380
Reading Hospital
West Reading, Pennsylvania, United States, 19611
Wexford Health and Wellness Pavilion
Wexford, Pennsylvania, United States, 15090
UPMC Susquehanna
Williamsport, Pennsylvania, United States, 17701
Asplundh Cancer Pavilion
Willow Grove, Pennsylvania, United States, 19090
Lankenau Medical Center
Wynnewood, Pennsylvania, United States, 19096
UPMC Memorial
York, Pennsylvania, United States, 17408
United States, South Carolina
AnMed Health Cancer Center
Anderson, South Carolina, United States, 29621
Saint Joseph's/Candler - Bluffton Campus
Bluffton, South Carolina, United States, 29910
Prisma Health Cancer Institute - Spartanburg
Boiling Springs, South Carolina, United States, 29316
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
Prisma Health Cancer Institute - Laurens
Clinton, South Carolina, United States, 29325
Prisma Health Cancer Institute - Easley
Easley, South Carolina, United States, 29640
McLeod Regional Medical Center
Florence, South Carolina, United States, 29506
Gibbs Cancer Center-Gaffney
Gaffney, South Carolina, United States, 29341
Tidelands Georgetown Memorial Hospital
Georgetown, South Carolina, United States, 29440
Saint Francis Hospital
Greenville, South Carolina, United States, 29601
Prisma Health Cancer Institute - Butternut
Greenville, South Carolina, United States, 29605
Prisma Health Cancer Institute - Faris
Greenville, South Carolina, United States, 29605
Saint Francis Cancer Center
Greenville, South Carolina, United States, 29607
Prisma Health Cancer Institute - Eastside
Greenville, South Carolina, United States, 29615
Self Regional Healthcare
Greenwood, South Carolina, United States, 29646
Prisma Health Cancer Institute - Greer
Greer, South Carolina, United States, 29650
Gibbs Cancer Center-Pelham
Greer, South Carolina, United States, 29651
South Carolina Cancer Specialists PC
Hilton Head Island, South Carolina, United States, 29926-3827
Levine Cancer Institute-Rock Hill
Rock Hill, South Carolina, United States, 29732
Prisma Health Cancer Institute - Seneca
Seneca, South Carolina, United States, 29672
Spartanburg Medical Center
Spartanburg, South Carolina, United States, 29303
MGC Hematology Oncology-Union
Union, South Carolina, United States, 29379
Lexington Medical Center
West Columbia, South Carolina, United States, 29169
United States, South Dakota
Avera Cancer Institute at Pierre
Pierre, South Dakota, United States, 57501
Rapid City Regional Hospital
Rapid City, South Dakota, United States, 57701
Sanford Cancer Center Oncology Clinic
Sioux Falls, South Dakota, United States, 57104
Avera Cancer Institute
Sioux Falls, South Dakota, United States, 57105
Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota, United States, 57117-5134
United States, Tennessee
Baptist Memorial Hospital and Cancer Center-Collierville
Collierville, Tennessee, United States, 38017
Vanderbilt-Ingram Cancer Center Cool Springs
Franklin, Tennessee, United States, 37067
Regional Cancer Center at Indian Path Community Hospital
Kingsport, Tennessee, United States, 37660
Thompson Cancer Survival Center
Knoxville, Tennessee, United States, 37916
Thompson Cancer Survival Center - West
Knoxville, Tennessee, United States, 37932
Thompson Oncology Group-Lenoir City
Lenoir City, Tennessee, United States, 37772
Thompson Oncology Group-Maryville
Maryville, Tennessee, United States, 37804
Baptist Memorial Hospital and Cancer Center-Memphis
Memphis, Tennessee, United States, 38120
Vanderbilt Breast Center at One Hundred Oaks
Nashville, Tennessee, United States, 37204
Vanderbilt University/Ingram Cancer Center
Nashville, Tennessee, United States, 37232
Thompson Oncology Group-Oak Ridge
Oak Ridge, Tennessee, United States, 37830
United States, Texas
The Don and Sybil Harrington Cancer Center
Amarillo, Texas, United States, 79106
Dell Seton Medical Center at The University of Texas
Austin, Texas, United States, 78701
Austin Cancer Centers-Central Austin
Austin, Texas, United States, 78702
Austin Cancer Centers-Saint David's
Austin, Texas, United States, 78705
Houston Methodist San Jacinto Hospital
Baytown, Texas, United States, 77521
MD Anderson in The Woodlands
Conroe, Texas, United States, 77384
Lyndon Baines Johnson General Hospital
Houston, Texas, United States, 77026-1967
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
Houston, Texas, United States, 77030
Ben Taub General Hospital
Houston, Texas, United States, 77030
Houston Methodist Hospital
Houston, Texas, United States, 77030
M D Anderson Cancer Center
Houston, Texas, United States, 77030
Methodist Willowbrook Hospital
Houston, Texas, United States, 77070
MD Anderson West Houston
Houston, Texas, United States, 77079
Houston Methodist West Hospital
Houston, Texas, United States, 77094
MD Anderson League City
League City, Texas, United States, 77573
Houston Methodist Saint John Hospital
Nassau Bay, Texas, United States, 77058
MD Anderson in Sugar Land
Sugar Land, Texas, United States, 77478
Houston Methodist Sugar Land Hospital
Sugar Land, Texas, United States, 77479
Houston Methodist The Woodlands Hospital
The Woodlands, Texas, United States, 77385
United States, Utah
Farmington Health Center
Farmington, Utah, United States, 84025
University of Utah Sugarhouse Health Center
Salt Lake City, Utah, United States, 84106
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, United States, 84112
South Jordan Health Center
South Jordan, Utah, United States, 84009
United States, Vermont
Norris Cotton Cancer Center-North
Saint Johnsbury, Vermont, United States, 05819
United States, Virginia
Wellmont Medical Associates-Bristol
Bristol, Virginia, United States, 24201
Inova Schar Cancer Institute
Fairfax, Virginia, United States, 22031
Augusta Health Center for Cancer and Blood Disorders
Fishersville, Virginia, United States, 22939
Peninsula Cancer Institute-Gloucester
Gloucester, Virginia, United States, 23061
Centra Lynchburg Hematology-Oncology Clinic Inc
Lynchburg, Virginia, United States, 24501
Bon Secours Memorial Regional Medical Center
Mechanicsville, Virginia, United States, 23116
Bon Secours Saint Francis Medical Center
Midlothian, Virginia, United States, 23114
Peninsula Cancer Institute-Newport News
Newport News, Virginia, United States, 23601
Southwest VA Regional Cancer Center
Norton, Virginia, United States, 24273
Bon Secours Saint Mary's Hospital
Richmond, Virginia, United States, 23226
Virginia Cancer Institute
Richmond, Virginia, United States, 23229
VCU Massey Cancer Center at Stony Point
Richmond, Virginia, United States, 23235
Virginia Commonwealth University/Massey Cancer Center
Richmond, Virginia, United States, 23298
VCU Community Memorial Health Center
South Hill, Virginia, United States, 23970
Peninsula Cancer Institute-Cancer Specialists of Tidewater
Virginia Beach, Virginia, United States, 23454
Peninsula Cancer Institute-Williamsburg
Williamsburg, Virginia, United States, 23185
Shenandoah Oncology PC
Winchester, Virginia, United States, 22601
United States, Washington
Providence Regional Cancer System-Aberdeen
Aberdeen, Washington, United States, 98520
Overlake Medical Center
Bellevue, Washington, United States, 98004
PeaceHealth Saint Joseph Medical Center
Bellingham, Washington, United States, 98225
Harrison HealthPartners Hematology and Oncology-Bremerton
Bremerton, Washington, United States, 98310
Providence Regional Cancer System-Centralia
Centralia, Washington, United States, 98531
Swedish Cancer Institute-Edmonds
Edmonds, Washington, United States, 98026
Kadlec Clinic Hematology and Oncology
Kennewick, Washington, United States, 99336
Seattle Cancer Care Alliance at EvergreenHealth
Kirkland, Washington, United States, 98034
Providence Regional Cancer System-Lacey
Lacey, Washington, United States, 98503
PeaceHealth Saint John Medical Center
Longview, Washington, United States, 98632
Skagit Valley Hospital Regional Cancer Care Center
Mount Vernon, Washington, United States, 98274
Skagit Valley Hospital
Mount Vernon, Washington, United States, 98274
Jefferson Healthcare
Port Townsend, Washington, United States, 98368
Harrison HealthPartners Hematology and Oncology-Poulsbo
Poulsbo, Washington, United States, 98370
Virginia Mason Medical Center
Seattle, Washington, United States, 98101
Fred Hutchinson Cancer Research Center
Seattle, Washington, United States, 98109
Seattle Cancer Care Alliance
Seattle, Washington, United States, 98109
Swedish Medical Center-First Hill
Seattle, Washington, United States, 98122-4307
Seattle Cancer Care Alliance at Northwest Hospital
Seattle, Washington, United States, 98133
University of Washington Medical Center - Montlake
Seattle, Washington, United States, 98195
Spokane Valley Cancer Center-Mayfair
Spokane, Washington, United States, 99208
PeaceHealth Southwest Medical Center
Vancouver, Washington, United States, 98664
Legacy Cancer Institute Medical Oncology and Day Treatment
Vancouver, Washington, United States, 98684
Legacy Salmon Creek Hospital
Vancouver, Washington, United States, 98686
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
Yakima, Washington, United States, 98902
United States, West Virginia
Edwards Comprehensive Cancer Center
Huntington, West Virginia, United States, 25701
United States, Wisconsin
Langlade Hospital and Cancer Center
Antigo, Wisconsin, United States, 54409
ThedaCare Regional Cancer Center
Appleton, Wisconsin, United States, 54911
Ascension Saint Elizabeth Hospital
Appleton, Wisconsin, United States, 54915
Duluth Clinic Ashland
Ashland, Wisconsin, United States, 54806
Ascension Southeast Wisconsin Hospital - Elmbrook Campus
Brookfield, Wisconsin, United States, 53045
Aurora Cancer Care-Southern Lakes VLCC
Burlington, Wisconsin, United States, 53105
Ascension Calumet Hospital
Chilton, Wisconsin, United States, 53014
Aurora Health Center-Fond du Lac
Fond Du Lac, Wisconsin, United States, 54937
Ascension Saint Francis - Reiman Cancer Center
Franklin, Wisconsin, United States, 53132
Aurora Health Care Germantown Health Center
Germantown, Wisconsin, United States, 53022
Aurora Cancer Care-Grafton
Grafton, Wisconsin, United States, 53024
Saint Vincent Hospital Cancer Center Green Bay
Green Bay, Wisconsin, United States, 54301
Saint Vincent Hospital Cancer Center at Saint Mary's
Green Bay, Wisconsin, United States, 54303
Aurora BayCare Medical Center
Green Bay, Wisconsin, United States, 54311
UW Cancer Center Johnson Creek
Johnson Creek, Wisconsin, United States, 53038
Aurora Cancer Care-Kenosha South
Kenosha, Wisconsin, United States, 53142
Gundersen Lutheran Medical Center
La Crosse, Wisconsin, United States, 54601
University of Wisconsin Carbone Cancer Center
Madison, Wisconsin, United States, 53792
Aurora Bay Area Medical Group-Marinette
Marinette, Wisconsin, United States, 54143
Saint Vincent Hospital Cancer Center at Marinette
Marinette, Wisconsin, United States, 54143
Aspirus Medford Hospital
Medford, Wisconsin, United States, 54451
Ascension Columbia Saint Mary's Hospital Ozaukee
Mequon, Wisconsin, United States, 53097
Aurora Cancer Care-Milwaukee
Milwaukee, Wisconsin, United States, 53209
Ascension Columbia Saint Mary's Hospital - Milwaukee
Milwaukee, Wisconsin, United States, 53211
Aurora Saint Luke's Medical Center
Milwaukee, Wisconsin, United States, 53215
Aurora Sinai Medical Center
Milwaukee, Wisconsin, United States, 53233
ProHealth D N Greenwald Center
Mukwonago, Wisconsin, United States, 53149
Cancer Center of Western Wisconsin
New Richmond, Wisconsin, United States, 54017
ProHealth Oconomowoc Memorial Hospital
Oconomowoc, Wisconsin, United States, 53066
Saint Vincent Hospital Cancer Center at Oconto Falls
Oconto Falls, Wisconsin, United States, 54154
Ascension Mercy Hospital
Oshkosh, Wisconsin, United States, 54904
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, Wisconsin, United States, 54904
Ascension All Saints Hospital
Racine, Wisconsin, United States, 53405
Aurora Cancer Care-Racine
Racine, Wisconsin, United States, 53406
Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan, Wisconsin, United States, 53081
Ascension Saint Michael's Hospital
Stevens Point, Wisconsin, United States, 54481
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Sturgeon Bay, Wisconsin, United States, 54235-1495
Aurora Medical Center in Summit
Summit, Wisconsin, United States, 53066
Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers, Wisconsin, United States, 54241
ProHealth Waukesha Memorial Hospital
Waukesha, Wisconsin, United States, 53188
UW Cancer Center at ProHealth Care
Waukesha, Wisconsin, United States, 53188
ThedaCare Cancer Care - Waupaca
Waupaca, Wisconsin, United States, 54981
Aspirus Regional Cancer Center
Wausau, Wisconsin, United States, 54401
Ascension Medical Group Southeast Wisconsin - Mayfair Road
Wauwatosa, Wisconsin, United States, 53226
Aurora Cancer Care-Milwaukee West
Wauwatosa, Wisconsin, United States, 53226
Aurora West Allis Medical Center
West Allis, Wisconsin, United States, 53227
Aspirus Cancer Care - Wisconsin Rapids
Wisconsin Rapids, Wisconsin, United States, 54494
United States, Wyoming
Billings Clinic-Cody
Cody, Wyoming, United States, 82414
Canada, Alberta
Tom Baker Cancer Centre
Calgary, Alberta, Canada, T2N 4N2
Cross Cancer Institute
Edmonton, Alberta, Canada, T6G 1Z2
Canada, British Columbia
BCCA-Fraser Valley Cancer Centre
Surrey, British Columbia, Canada, V3V 1Z2
BCCA-Vancouver Cancer Centre
Vancouver, British Columbia, Canada, V5Z 4E6
Canada, New Brunswick
The Moncton Hospital
Moncton, New Brunswick, Canada, E1C 6Z8
Atlantic Health Sciences Corporation-Saint John Regional Hospital
Saint John, New Brunswick, Canada, E2L 4L2
Canada, Newfoundland and Labrador
Doctor H. Bliss Murphy Cancer Centre
St. John's, Newfoundland and Labrador, Canada, A1B 3V6
Canada, Ontario
Juravinski Cancer Centre at Hamilton Health Sciences
Hamilton, Ontario, Canada, L8V 5C2
Grand River Regional Cancer Centre at Grand River Hospital
Kitchener, Ontario, Canada, N2G 1G3
London Regional Cancer Program
London, Ontario, Canada, N6A 4L6
Stronach Regional Health Centre at Southlake
Newmarket, Ontario, Canada, L3Y 2P9
Algoma District Cancer Program Sault Area Hospital
Sault Ste Marie, Ontario, Canada, P6B 0A8
Humber River Hospital
Toronto, Ontario, Canada, M3M 0B2
Odette Cancer Centre- Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada, M4N 3M5
Canada, Quebec
Hopital de la Cite-de-la-Sante
Laval, Quebec, Canada, H7M 3L9
The Research Institute of the McGill University Health Centre (MUHC)
Montreal, Quebec, Canada, H3H 2R9
Jewish General Hospital
Montreal, Quebec, Canada, H3T 1E2
Hopital Du Sacre-Coeur de Montreal
Montreal, Quebec, Canada, H4J 1C5
CHU de Quebec-Hopital du Saint-Sacrement (HSS)
Quebec City, Quebec, Canada, G1S 4L8
Canada, Saskatchewan
Allan Blair Cancer Centre
Regina, Saskatchewan, Canada, S4T 7T1
Puerto Rico
Cancer Center-Metro Medical Center Bayamon
Bayamon, Puerto Rico, 00959-5060
Doctors Cancer Center
Manati, Puerto Rico, 00674
San Juan Community Oncology Group
San Juan, Puerto Rico, 00917
San Juan City Hospital
San Juan, Puerto Rico, 00936
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