Trends, Charts, and Maps
ClinicalTrials.gov currently lists 467,212 studies with locations in all 50 States and in 221 countries.
As of March 2021, ClinicalTrials.gov receives about 4.5 million visitors monthly.
Contents
- Locations of Registered Studies
- Locations of Recruiting Studies
- Map of Studies Registered on ClinicalTrials.gov
- Types of Registered Studies
- Number of Registered Studies Over Time
- Number of Registered Studies With Posted Results Over Time
Locations of Registered Studies
The chart below shows the distribution of locations for all studies registered on ClinicalTrials.gov.
Percentage of Registered Studies by Location (as of September 25, 2023)
Total of 467,212 studies
| ██ | Non-U.S. only (54%) |
| ██ | U.S. only (31%) |
| ██ | Both U.S. and non-U.S. (5%) |
| ██ | Not provided (11%) |
| Location | Number of Registered Studies and Percentage of Total (as of September 25, 2023) |
|---|---|
| Non-U.S. only | 250,362 (54%) |
| U.S. only | 143,311 (31%) |
| Both U.S. and non-U.S. | 22,722 (5%) |
| Not provided | 50,817 (11%) |
| Total | 467,212 (100%) |
Locations of Recruiting Studies
The chart below shows the distribution of locations for recruiting studies registered on ClinicalTrials.gov.
Percentage of Recruiting Studies by Location (as of September 25, 2023)
Total of 65,465 recruiting studies
| ██ | Non-U.S. only (63%) |
| ██ | U.S. only (31%) |
| ██ | Both U.S. and non-U.S. (5%) |
| Location | Number of Recruiting Studies and Percentage of Total (as of September 25, 2023) |
|---|---|
| Non-U.S. only | 41,279 (63%) |
| U.S. only | 20,520 (31%) |
| Both U.S. and non-U.S. | 3,425 (5%) |
| Not provided | 241 (0%) |
| Total | 65,465 (100%) |
Map of Studies Registered on ClinicalTrials.gov
The See Studies on Map page provides an interactive map of studies that are registered on ClinicalTrials.gov.
Types of Registered Studies
The table below shows the number and types of studies that are registered and have results posted on ClinicalTrials.gov.
| Study and Intervention Type (as of September 25, 2023) |
Number of Registered Studies and Percentage of Total | Number of Studies With Posted Results and Percentage of Total*** | |
|---|---|---|---|
| Total |
467,212 | 60,199 | |
| Interventional | 359,579 (77%) | 56,860 (94%) | |
| Type of Intervention* | Drug or biologic | 185,633 | 42,462 |
| Behavioral, other | 125,781 | 12,007 | |
| Surgical procedure | 37,283 | 2,940 | |
| Device** | 48,422 | 8,427 | |
| Observational | 105,852 (23%) | 3,339 (6%) | |
| Expanded Access | 911 | N/A | |
* A study may include more than one type of intervention, meaning that a single study may be counted more than once.
Because of this, the sum of counts by type of intervention do not equal the total number of interventional studies.
** A total of
870
applicable device clinical trials were submitted as "delayed posting" under the Food and Drug Administration Amendments Act of 2007 (FDAAA).
That is, the Responsible Party indicated that the trial includes a device not previously approved or cleared by the Food and Drug Administration (U.S. FDA) for any use.
These trials are not included in the counts of trials with at least one device.
*** Results are required to be submitted only for certain studies.
For example, results submission is generally not required for observational studies; trials completed before 2008; and trials that include drug, biological, or device products not previously approved by the U.S. FDA for any use (if the Primary Completion Date is before January 18, 2017).
See FDAAA 801 and the Final Rule for further information.
N/A = not applicable
Number of Registered Studies Over Time
The graph and table below show the total number of studies posted on ClinicalTrials.gov since 2000, based on the First Posted date. The first version of ClinicalTrials.gov was made available to the public on February 29, 2000.
Key:
ICMJE: Indicates when the International Committee of Medical Journal Editors (ICMJE) began requiring trial registration as a condition of publication (September 2005)
FDAAA: Indicates when the registration requirements of FDAAA began and were implemented on ClinicalTrials.gov (December 2007)
Number of Registered Studies by Year (as of September 25, 2023)
| Year First Posted | Start of Year | During Year | End of Year |
|---|---|---|---|
| 2000 † | 1,255 † | 2,119 | 2,119 |
| 2001 | 2,119 | 1,773 | 3,892 |
| 2002 | 3,892 | 1,378 | 5,270 |
| 2003 | 5,270 | 3,588 | 8,858 |
| 2004 | 8,858 | 3,166 | 12,024 |
| 2005 | 12,024 | 12,798 | 24,822 |
| 2006 | 24,822 | 10,917 | 35,739 |
| 2007 | 35,739 | 12,549 | 48,288 |
| 2008 | 48,288 | 17,564 | 65,852 |
| 2009 | 65,852 | 17,008 | 82,860 |
| 2010 | 82,860 | 17,345 | 100,205 |
| 2011 | 100,205 | 17,816 | 118,021 |
| 2012 | 118,021 | 19,463 | 137,484 |
| 2013 | 137,484 | 20,431 | 157,915 |
| 2014 | 157,915 | 23,310 | 181,225 |
| 2015 | 181,225 | 24,106 | 205,331 |
| 2016 | 205,331 | 27,787 | 233,118 |
| 2017 | 233,118 | 29,175 | 262,293 |
| 2018 | 262,293 | 30,950 | 293,243 |
| 2019 | 293,243 | 32,514 | 325,757 |
| 2020 | 325,757 | 36,722 | 362,479 |
| 2021 | 362,479 | 37,016 | 399,495 |
| 2022 | 399,495 | 38,030 | 437,525 |
| 2023 | 437,525 | 29,687 ‡ | 467,212 ‡ |
† ClinicalTrials.gov was first launched on February 29, 2000 with 1,255 studies available
‡ As of September 25, 2023
Number of Registered Studies With Posted Results Over Time
The graph and table below show the number of registered studies with results posted on ClinicalTrials.gov, based on the Results First Posted date. ClinicalTrials.gov launched its results database in September 2008, at which time sponsors or investigators could begin submitting results for their registered studies. The results database was first developed to accommodate the results submission requirements outlined in FDAAA. See About the Results Database for more information.
Number of Registered Studies With Posted Results by Year (as of September 25, 2023)
| Year Results First Posted | Start of Year | During Year | End of Year |
|---|---|---|---|
| 2008 † | 0 † | 41 | 41 |
| 2009 | 41 | 1,098 | 1,139 |
| 2010 | 1,139 | 1,617 | 2,756 |
| 2011 | 2,756 | 2,200 | 4,956 |
| 2012 | 4,956 | 2,804 | 7,760 |
| 2013 | 7,760 | 3,093 | 10,853 |
| 2014 | 10,853 | 4,827 | 15,680 |
| 2015 | 15,680 | 3,801 | 19,481 |
| 2016 | 19,481 | 4,185 | 23,666 |
| 2017 | 23,666 | 5,827 | 29,493 |
| 2018 | 29,493 | 4,659 | 34,152 |
| 2019 | 34,152 | 6,523 | 40,675 |
| 2020 | 40,675 | 6,043 | 46,718 |
| 2021 | 46,718 | 5,819 | 52,537 |
| 2022 | 52,537 | 4,024 | 56,561 |
| 2023 | 56,561 | 3,638 ‡ | 60,199 ‡ |
† ClinicalTrials.gov Results Database was launched in September 2008, but initially held no results
‡ As of September 25, 2023