EMPACT-MI: A Study to Test Whether Empagliflozin Can Lower the Risk of Heart Failure and Death in People Who Had a Heart Attack (Myocardial Infarction)
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT04509674 |
Recruitment Status :
Completed
First Posted : August 12, 2020
Last Update Posted : November 14, 2023
|
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This is a study in adults who had a heart attack (myocardial infarction). The purpose of this study is to find out whether a medicine called empagliflozin helps to lower the chances of having to go to the hospital for heart failure and whether it lowers the chances of dying from cardiovascular disease.
People who are in hospital may join the study soon after being treated for their heart attack. Participants are put into 2 groups by chance. One group takes 1 empagliflozin tablet a day. The other group takes 1 placebo tablet a day. Placebo tablets look like empagliflozin tablets but do not contain any medicine. All participants continue their standard treatment. Empagliflozin belongs to a class of medicines known as SGLT-2 inhibitors. Empagliflozin is a medicine that helps people with type 2 diabetes to lower their blood sugar. Researchers think that empagliflozin might also help people after heart attack who are at risk for heart failure, whether or not they have diabetes.
Participants are in the study for about 1 to 2 years. During this time, there are about 4 visits inperson, 2 visits are done either by phone or by use of an mobile application. Results between the empagliflozin and placebo groups are compared. The doctors also regularly check the general health of the participants.
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Myocardial Infarction | Drug: Empagliflozin Drug: Placebo | Phase 3 |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 6522 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) |
Masking Description: | Blinded investigator review of events in place of centralized adjudication. |
Primary Purpose: | Treatment |
Official Title: | EMPACT-MI: A Streamlined, Multicentre, Randomised, Parallel Group, Double-blind Placebo-controlled Superiority Trial to Evaluate the Effect of EMPAgliflozin on Hospitalisation for Heart Failure and Mortality in Patients With aCuTe Myocardial Infarction |
Actual Study Start Date : | December 16, 2020 |
Actual Primary Completion Date : | November 5, 2023 |
Actual Study Completion Date : | November 5, 2023 |
Arm | Intervention/treatment |
---|---|
Experimental: Empagliflozin |
Drug: Empagliflozin
Empagliflozin |
Placebo Comparator: Placebo |
Drug: Placebo
Placebo |
- Composite of time to first heart failure hospitalisation or all-cause mortality [ Time Frame: up to 26 months ]
- Total number of HHF or all-cause mortality [ Time Frame: up to 26 months ]
- Total number of non-elective Cardiovascular (CV) hospitalisations or all-cause mortality [ Time Frame: up to 26 months ]
- Total number of non-elective all-cause hospitalisations or all-cause mortality [ Time Frame: up to 26 months ]
- Total number of hospitalisations for MI or all-cause mortality [ Time Frame: up to 26 months ]
- Time to CV mortality [ Time Frame: up to 26 months ]
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 18 Years and older (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Of full age of consent (according to local legislation, at least ≥ 18 years) at screening.
- Signed and dated written informed consent in accordance with ICH-GCP and local legislation prior to admission to the trial.
- Male or female patients. Women of childbearing potential (WOCBP) must be ready and able to use highly effective methods of birth control per ICH M3 (R2) that result in a low failure rate of less than 1% per year when used consistently and correctly. A list of contraception methods meeting these criteria is provided in the patient information.
- Diagnosis of spontaneous Acute Myocardial Infarction (AMI): ST-Elevation Myocardial Infarction (STEMI) or Non-ST Elevation Myocardial Infarction (NSTEMI) with randomisation to occur no later than 14 calendar days after hospital admission. For patients with an in-hospital Myocardial Infarction (MI) as qualifying event, randomization must still occur within 14 days of hospital admission.
-
High risk of HF, defined as EITHER
-
Symptoms (e.g. dyspnea; decreased exercise tolerance; fatigue), or signs of congestion (e.g. pulmonary rales, crackles or crepitations; elevated jugular venous pressure; congestion on chest X-ray), that require treatment (e.g. augmentation or initiation of oral diuretic therapy; i.v. diuretic therapy; i.v. vasoactive agent; mechanical intervention etc.) at any time during the hospitalization.
OR
- Newly developed Left Ventricular Ejection Fraction (LVEF) < 45% as measured by echocardiography, ventriculography, cardiac Computer Tomography (CT), Magnetic Resonance Imaging (MRI) or radionuclide imaging during index hospitalisation.
-
-
In addition at least one of the following risk factors:
- Age > 65 years,
- Newly developed LVEF < 35%,
- Prior MI (before index MI) documented in medical records,
- Estimated Glomerular Filtration Rate (eGFR) < 60 ml/min/1.73m2 (using Chronic Kidney Disease Epidemiology Collaboration Equation (CKD-EPI) formula based on creatinine from local lab at any time during index hospitalisation),
- Atrial fibrillation (persistent or permanent ; if paroxysmal, only valid if associated with index MI),
- Type 2 diabetes mellitus (prior or new diagnosis),
- N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) >1,400 pg/mL for patients in sinus rhythm, >2,800 pg/mL if atrial fibrillation; Brain Natriuretic Peptide (BNP) >350 pg/mL for patients in sinus rhythm, >700 pg/mL if atrial fibrillation, measured at any time during hospitalisation,
- Uric acid >7.5 mg/dL (>446 μmol/L), measured at any time during hospitalisation,
- Pulmonary Artery Systolic Pressure [or right ventricular systolic pressure] >40 mmHg (non-invasive [usually obtained from clinically indicated post-MI echocardiography] or invasive, at any time during hospitalisation),
- Patient not revascularized (and no planned revascularization) for the index MI (Includes e.g. patients where no angiography is performed, unsuccessful revascularization attempts, diffuse atherosclerosis not amenable for intervention; but does NOT include if revascularization was not performed due to nonobstructive coronary arteries),
- 3-vessel coronary artery disease at time of index MI,
- Diagnosis of peripheral artery disease (extracoronary vascular disease, e.g. lower extremity artery disease or carotid artery disease).
Exclusion Criteria:
- Diagnosis of chronic Heart Failure (HF) prior to index MI.
- Systolic blood pressure < 90 mmHg at randomisation.
- Cardiogenic shock or use of i.v. inotropes in last 24 hours before randomisation.
- Coronary Artery Bypass Grafting planned at time of randomisation.
- Current diagnosis of Takotsubo cardiomyopathy.
- Any current severe (stenotic or regurgitant) valvular heart disease.
- eGFR < 20 ml/min/1.73m2 (using CKD-EPI formula based on most recent creatinine from local lab during index hospitalisation) or on dialysis.
- Type I diabetes mellitus. Further exclusion criteria apply.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04509674
United States, Alabama | |
Advanced Cardiovascular LLC | |
Alexander City, Alabama, United States, 35010 | |
Grandview Medical Center | |
Birmingham, Alabama, United States, 35243 | |
Heart Center Research, LLC | |
Huntsville, Alabama, United States, 35801 | |
United States, Arizona | |
Mercy Gilbert Medical Center | |
Gilbert, Arizona, United States, 85297 | |
United States, Arkansas | |
Arkansas Cardiology, PA | |
Little Rock, Arkansas, United States, 72205 | |
United States, California | |
Comprehensive Cardiovascular Medical Group | |
Bakersfield, California, United States, 93309 | |
Valley Clinical Trials, Inc. | |
Covina, California, United States, 91723 | |
Cardiovascular Innovation and Research Center | |
Long Beach, California, United States, 90813 | |
University of California Los Angeles | |
Los Angeles, California, United States, 90095 | |
InvivoCure | |
Mission Hills, California, United States, 91346 | |
Valley Clinical Trials, Inc. | |
Northridge, California, United States, 91325 | |
Valley Clinical Trials, Inc. | |
Pasadena, California, United States, 91105 | |
Kaiser Permanente | |
San Diego, California, United States, 92123 | |
San Diego Cardiac Center | |
San Diego, California, United States, 92123 | |
The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | |
Torrance, California, United States, 90502 | |
Interventional Cardiology Medical Group | |
West Hills, California, United States, 91307 | |
United States, District of Columbia | |
George Washington University Medical Faculty Associates | |
Washington, District of Columbia, United States, 20037 | |
United States, Florida | |
Clearwater Cardiovascular Consultants | |
Clearwater, Florida, United States, 33756 | |
Integrative Research Associates | |
Fort Lauderdale, Florida, United States, 33312 | |
University of Florida Health Jacksonville | |
Jacksonville, Florida, United States, 32209 | |
Cardiology Partners Clinical Research Institute | |
Palm Beach Gardens, Florida, United States, 33410 | |
Charlotte Heart Group Research Center | |
Port Charlotte, Florida, United States, 33952 | |
United States, Georgia | |
Grady Memorial Hospital | |
Atlanta, Georgia, United States, 30303 | |
Cardiovascular Consultants of South Georgia, LLC | |
Thomasville, Georgia, United States, 31792 | |
Atlanta Heart Specialists, LLC | |
Tucker, Georgia, United States, 30084 | |
United States, Illinois | |
Advanced Heart Care, LLC, Medicoricum, LLC | |
Fairview Heights, Illinois, United States, 62208 | |
United States, Indiana | |
Midwest Cardiovascular Research and Education Foundation | |
Elkhart, Indiana, United States, 46514 | |
Cardiovascular Research of Northwest Indiana, LLC | |
Munster, Indiana, United States, 46321 | |
Reid Physician Associates | |
Richmond, Indiana, United States, 47374 | |
United States, Kansas | |
Midwest Heart and Vascular Specialists | |
Overland Park, Kansas, United States, 66211 | |
United States, Kentucky | |
University of Kentucky Medical Center | |
Lexington, Kentucky, United States, 40536-0200 | |
University of Louisville | |
Louisville, Kentucky, United States, 40202 | |
United States, Maine | |
Eastern Maine Medical Center | |
Bangor, Maine, United States, 04401 | |
United States, Maryland | |
Cardiovascular Specialists of Central Maryland | |
Columbia, Maryland, United States, 21044 | |
Shady Grove Adventist Hospital | |
Rockville, Maryland, United States, 20850 | |
United States, Michigan | |
Healthy Heart Cardiology | |
Grand Rapids, Michigan, United States, 49546 | |
Western Michigan University | |
Kalamazoo, Michigan, United States, 49009 | |
Mid Michigan Medical Center | |
Midland, Michigan, United States, 48670 | |
Michigan Heart, PC | |
Ypsilanti, Michigan, United States, 48197 | |
United States, Minnesota | |
Minneapolis Heart Institute Foundation | |
Minneapolis, Minnesota, United States, 55407 | |
United States, Mississippi | |
Cardiology Associates Research, LLC | |
Tupelo, Mississippi, United States, 38801 | |
United States, Missouri | |
Missouri Cardiovascular Specialists, LLP | |
Columbia, Missouri, United States, 65201 | |
University of Missouri Health System | |
Columbia, Missouri, United States, 65212 | |
North Kansas City Hospital | |
North Kansas City, Missouri, United States, 64116 | |
Gateway Cardiology, PC | |
Saint Louis, Missouri, United States, 63128 | |
St. Louis Heart and Vascular, P.C. | |
Saint Louis, Missouri, United States, 63136 | |
United States, New Jersey | |
Holy Name Medical Center | |
Hackensack, New Jersey, United States, 07601 | |
AtlantiCare | |
Pomona, New Jersey, United States, 08240 | |
The Heart House | |
Vineland, New Jersey, United States, 08360 | |
United States, New York | |
SJH Cardiology Associates | |
Liverpool, New York, United States, 13088 | |
Stony Brook University Hospital | |
Stony Brook, New York, United States, 11794 | |
United States, North Carolina | |
Asheville Cardiology Associates | |
Asheville, North Carolina, United States, 28803 | |
The University of North Carolina at Chapel Hill | |
Chapel Hill, North Carolina, United States, 27517 | |
Duke University Medical Center | |
Durham, North Carolina, United States, 27705 | |
Moses H. Cone Memorial Hospital | |
Greensboro, North Carolina, United States, 27401 | |
Medication Management, LLC | |
Greensboro, North Carolina, United States, 27405 | |
North Carolina Heart and Vascular | |
Raleigh, North Carolina, United States, 27607 | |
United States, North Dakota | |
Trinity Health Center Medical Arts | |
Minot, North Dakota, United States, 58701 | |
United States, Ohio | |
Aultman Hospital | |
Canton, Ohio, United States, 44710 | |
Cincinnati VA Medical Center | |
Cincinnati, Ohio, United States, 45220 | |
Kettering Medical Center | |
Kettering, Ohio, United States, 45429 | |
United States, Oklahoma | |
Oklahoma Heart Hospital Research Foundation, Incorporated | |
Oklahoma City, Oklahoma, United States, 73120 | |
South Oklahoma Heart Research Group | |
Oklahoma City, Oklahoma, United States, 73135 | |
United States, Pennsylvania | |
Capital Area Research, LLC | |
Camp Hill, Pennsylvania, United States, 17011 | |
Penn Presbyterian Medical Center | |
Philadelphia, Pennsylvania, United States, 19104 | |
Guthrie Medical Group PC | |
Sayre, Pennsylvania, United States, 18840 | |
United States, South Carolina | |
Upstate Cardiology, PA | |
Greenville, South Carolina, United States, 29607 | |
Carolina Heart Specialists, LLC | |
Lancaster, South Carolina, United States, 29720 | |
United States, South Dakota | |
Monument Health | |
Rapid City, South Dakota, United States, 57701 | |
United States, Tennessee | |
Centennial Heart Cardiovascular Consultants, LLC | |
Nashville, Tennessee, United States, 37203 | |
Parkway Cardiology Associates | |
Oak Ridge, Tennessee, United States, 37830 | |
Cardiovascular Research of Knoxville | |
Powell, Tennessee, United States, 37849 | |
United States, Texas | |
Texas Health Presbyterian Hospital Allen | |
Allen, Texas, United States, 75013 | |
Amarillo Heart Clinical Research Institute, Incorporated | |
Amarillo, Texas, United States, 79106 | |
Pharmatex Research | |
Amarillo, Texas, United States, 79109 | |
Dallas VA Medical Center | |
Dallas, Texas, United States, 75216 | |
Baylor Scott and White Health | |
Plano, Texas, United States, 75093 | |
South Texas Cardiovascular Consultants | |
San Antonio, Texas, United States, 78201 | |
Revival Research Institute, LLC. | |
Sherman, Texas, United States, 75092 | |
Cardiovascular Associates of East Texas, PA | |
Tyler, Texas, United States, 75701 | |
United States, Virginia | |
Carient Heart and Vascular | |
Manassas, Virginia, United States, 20109 | |
Riverside Regional Medical Center | |
Newport News, Virginia, United States, 23601 | |
Tidewater Physicians Multispecialty Group | |
Newport News, Virginia, United States, 23606 | |
Sentara Hospitals | |
Norfolk, Virginia, United States, 23507 | |
Roanoke Heart Institute PLC | |
Roanoke, Virginia, United States, 24014 | |
Argentina | |
Instituto Cardiovascular de Buenos Aires | |
Belgrano, Argentina, C1428ART | |
Fundacion Sanatorio Güemes | |
Ciudad Autonoma Buenos Aires, Argentina, C1180 AAX | |
Hospital Italiano de Córdoba | |
Cordoba, Argentina, X5000 | |
Sanatorio Allende | |
Cordoba, Argentina, X5000 | |
Centro Medico Luquez | |
Cordoba, Argentina, X5006CBI | |
Hospital Privado Centro Medico de Cordoba | |
Cordoba, Argentina, X5016KEH | |
Clinica Privada del Prado | |
Cordoba, Argentina, X5020AAA | |
Centro de Investigacion Clinica Coronel Suarez | |
Coronel Suarez, Argentina, B7540GHD | |
Instituto de Cardiología de Corrientes | |
Corrientes, Argentina, 3400 | |
Fundación Favaloro para la Docencia e Investigación Medica | |
Monserrat, Argentina, C1093AAS | |
Sanatorio Modelo de Quilmes | |
Quilmes, Argentina, B1878GEG | |
Instituto Cardiovascular de Rosario | |
Rosario, Argentina, S2000 | |
Sanatorio Delta | |
Rosario, Argentina, S2000 | |
Sanatorio Parque | |
Rosario, Argentina, S2000 | |
Corporacion Medica de Gral. San Martin S.A. | |
San Martin, Argentina, B1650CSP | |
Centro Privado de Cardiología | |
San Miguel de Tucuman, Argentina, 4000 | |
Clinica U.O.M. | |
San Nicolas, Argentina, 2900 | |
Sanatorio Diagnóstico | |
Santa Fe, Argentina, 3081 | |
Hospital "Dr. José Maria Cullen" | |
Santa Fé, Argentina, S3000EOZ | |
Clinica Privada Fusavim SRL | |
Villa Maria, Argentina, 5900 | |
Australia, New South Wales | |
Concord Repatriation General Hospital | |
Concord, New South Wales, Australia, 2139 | |
South Western Sydney Local Health District | |
Liverpool, New South Wales, Australia, 2170 | |
Royal North Shore Hospital | |
St Leonards, New South Wales, Australia, 2065 | |
Westmead Hospital | |
Westmead, New South Wales, Australia, 2145 | |
Australia, Queensland | |
The Prince Charles Hospital | |
Chermside, Queensland, Australia, 4032 | |
Royal Brisbane and Women's Hospital | |
Herston, Queensland, Australia, 4029 | |
Gold Coast University Hospital | |
Southport, Queensland, Australia, 4215 | |
Australia, Victoria | |
Alfred Hospital | |
Melbourne, Victoria, Australia, 3004 | |
Brazil | |
JMF Clinica Do Coracao LTDA | |
Aracaju - SE, Brazil, 49055-530 | |
Hospital Santa Isabel | |
Balneario Camboriu, Brazil, 88331-085 | |
Hospital Madre Teresa | |
Belo Horizonte, Brazil, 30441-070 | |
Hospital do Coracao do Brasil | |
Brasilia, Brazil, 70390 700 | |
Hospital Angelina Caron | |
Campina Grande do Sul, Brazil, 83430-000 | |
Centro Especializado em Cardiol Loema Instituto de Pesq Clin | |
Campinas, Brazil, 13010-001 | |
IPECC - Instituto de Pesquisa Clínica de Campinas | |
Campinas, Brazil, 13060-080 | |
Hospital de Messejana Dr. Carlos Alberto Studart Gomes | |
Fortaleza, Brazil, 60840-285 | |
HC-UFG - Hospital das Clínicas da Universidade Federal de Goiás | |
Goiania, Brazil, 74605-020 | |
Hospital Regional Hans Dieter Schmidt | |
Joinville, Brazil, 89227-680 | |
Santa Casa de Misericórdia de Marília | |
Marília, Brazil, 17515-000 | |
Hospital São Vicente de Paulo | |
Passo Fundo, Brazil, 99010-080 | |
Hospital Sao Lucas da PUCRS | |
Porto Alegre, Brazil, 01046 010 | |
Instituto de Cardiologia Rio Grande do Sul | |
Porto Alegre, Brazil, 90620-001 | |
Hospital Nossa Senhora da Conceição | |
Porto Alegre, Brazil, 91350-200 | |
Hospital Agamenon Magalhaes | |
Recife, Brazil, 52051-380 | |
Fundacao de apoio ao ensino e assitencia HCFMRP | |
Ribeirao Preto, Brazil, 14051-140 | |
Hospital Copa D'or | |
Rio de Janeiro, Brazil, 22031-011 | |
Instituto de Ensino E Pesquisa Do Hospital Da Bahia | |
Salvador, Brazil, 41810-011 | |
Hospital de Base - Fac Med de Sao Jose do Rio Preto | |
Sao Jose do Rio Preto, Brazil, 15090-000 | |
Hospital Samaritano | |
Sao Paulo, Brazil, 01333-030 | |
Hospital Sao Luiz Jabaquara | |
Sao Paulo, Brazil, 04321-120 | |
Hospital Sao Luiz Morumbi | |
Sao Paulo, Brazil, 04544-000 | |
Hospital das Clínicas de Sao Paulo - INCOR | |
Sao Paulo, Brazil, 05403-000 | |
CEMEC - Centro Multidisciplinar de Estudos Clínicos | |
São Bernardo do Campo, Brazil, 09715-090 | |
Santa Casa de Votuporanga | |
Votuporanga, Brazil, 15500-003 | |
Bulgaria | |
Multiprofile Hospital For Active Treatment Pulse AD | |
Blagoevgrad, Bulgaria, 2700 | |
Multiprofile Hospital For Active Treatment "Dr. Tota Venkova" AD | |
Gabrovo, Bulgaria, 5300 | |
Multiprofile Hospital for Active Treatment AD Haskovo | |
Haskovo, Bulgaria, 6304 | |
Multiprofile Hospital For Active Treatment - Pazardzhik AD | |
Pazardzhik, Bulgaria, 4400 | |
Specialized Hospital for Active Treatment Sv. Georgi - Pernik | |
Pernik, Bulgaria, 2300 | |
Multiprofile Hospital for Active Treatment Heart and Brain EAD | |
Pleven, Bulgaria, 5804 | |
SHAT in Cardiology EAD, Pleven | |
Pleven, Bulgaria, 5804 | |
Medical Center Medconsult Pleven LTD | |
Pleven, Bulgaria, 5808 | |
Hospital MHAT Plovdiv, AD | |
Plovdiv, Bulgaria, 4003 | |
National Heart Hospital, Sofia | |
Sofia, Bulgaria, 1309 | |
City Clin.Univ.MPHAT EOOD,Clin.of Cardiology, Sofia | |
Sofia, Bulgaria, 1407 | |
University Multiprofile Hospital for Active Treatement "Alexandrovska" EAD | |
Sofia, Bulgaria, 1431 | |
UMHAT "Tsaritsa Yoannalsul" | |
Sofia, Bulgaria, 1527 | |
Medical Military Academy MHAT Sofia | |
Sofia, Bulgaria, 1606 | |
Multiprofile Hospital MHATEM 'Pirogov', Sofia | |
Sofia, Bulgaria, 1606 | |
MHAT Sv.Anna, Clinic of Internal Diseases, Sofia | |
Sofia, Bulgaria, 1750 | |
Hospital Trakia Park | |
Stara Zagora, Bulgaria, 6004 | |
Canada, Alberta | |
Heritage Medical Research Clinic | |
Calgary, Alberta, Canada, T2N 4Z6 | |
Royal Alexandra Hospital | |
Edmonton, Alberta, Canada, T5H 3V9 | |
University of Alberta Hospital (University of Alberta) | |
Edmonton, Alberta, Canada, T6G 2B7 | |
Canada, British Columbia | |
Royal Inland Hospital | |
Kamloops, British Columbia, Canada, V2C 2T1 | |
Surrey Memorial Hospital | |
Surrey, British Columbia, Canada, V3V 0C6 | |
Vancouver General Hospital | |
Vancouver, British Columbia, Canada, V5Z 1M9 | |
Victoria Heart Institute Foundation | |
Victoria, British Columbia, Canada, V8R 1B2 | |
Canada, Manitoba | |
St. Boniface Hospital | |
Winnipeg, Manitoba, Canada, R2H 2A6 | |
Canada, New Brunswick | |
GA Research Associates Ltd. | |
Moncton, New Brunswick, Canada, E1G 1A7 | |
Canada, Nova Scotia | |
QEII Health Sciences Centre | |
Halifax, Nova Scotia, Canada, B3H 3A7 | |
Canada, Ontario | |
William Osler Health Centre | |
Brampton, Ontario, Canada, L6R 3J7 | |
Queen's University | |
Kingston, Ontario, Canada, K7L 2V7 | |
One Heart Care Ventures | |
Mississauga, Ontario, Canada, L4Y 1M3 | |
Southlake Regional Health Centre | |
Newmarket, Ontario, Canada, L3Y 2P7 | |
Peterborough Regional Health Centre | |
Peterborough, Ontario, Canada, K9J 7C6 | |
Heart Health Institute | |
Scarborough, Ontario, Canada, M1B 4Z8 | |
Women's College Hospital | |
Toronto, Ontario, Canada, M5S 1B2 | |
Canada, Quebec | |
Montreal Heart Institute | |
Montreal, Quebec, Canada, H1T 1C8 | |
Centre Hospitalier de l'Universite de Montreal (CHUM) | |
Montreal, Quebec, Canada, H2X 0A9 | |
Montreal General Hospital - McGill University Health Centre | |
Montreal, Quebec, Canada, H3G 1A4 | |
McGill University Health Centre (MUHC) | |
Montreal, Quebec, Canada, H4A 3J1 | |
IUCPQ (Laval University) | |
Sainte-Foy, Quebec, Canada, G1V 4G5 | |
CIUSSS de l Estrie-CHUS | |
Sherbrooke, Quebec, Canada, J1H 5N4 | |
CSSS du Sud de Lanaudiere - Hopital Pierre-Le Gardeur | |
Terrebonne (Lachenaie), Quebec, Canada, J6V 2H2 | |
CIUSSS de la Mauricie-et-du-Centre-du-Quebec | |
Trois-Rivieres, Quebec, Canada, G8Z 3R9 | |
Canada, Saskatchewan | |
Prairie Vascular Research Inc. | |
Regina, Saskatchewan, Canada, S4P 0W5 | |
Canada | |
Oakville Trafalgar Memorial Hospital | |
Oakville, Canada, L6M 0L8 | |
China | |
Beijing Chao-Yang Hospital | |
Beijing, China, 100020 | |
Chinese PLA General Hospital | |
Beijing, China, 100022 | |
China-Japan Friendship Hospital | |
Beijing, China, 100029 | |
Peking University First Hospital | |
Beijing, China, 100034 | |
Beijing Luhe Hospital Capital Medical University | |
Beijing, China, 101100 | |
Changsha Central Hospital | |
Changsha, China, 410007 | |
Xiangya Hospital, Central South University | |
Changsha, China, 410008 | |
Guangdong Provincial People's Hospital | |
Guangzhou, China, 510100 | |
The First Affiliated Hospital of Harbin Medical University | |
Haerbin, China, 150001 | |
Hainan General Hospital | |
Haikou, China, 570311 | |
Shulan(Hanghzhou) Hospital | |
Hangzhou, China, 310004 | |
Zhejiang Hospital | |
Hangzhou, China, 310013 | |
Sir Run Run Shaw Hospital, Zhejiang University, School of Medicine | |
Hangzhou, China, 310016 | |
The Second Affiliated Hospital of Lanzhou Medical University | |
Lanzhou, China, 730030 | |
Nanjing Drum Tower Hospital | |
Nanjing, China, 210008 | |
Zhongshan Hospital Fudan University | |
Shanghai, China, 200032 | |
People's Hospital of Liaoning Province | |
Shenyang, China, 110016 | |
Peking University Shenzhen Hospital | |
Shenzhen, China, 518036 | |
Renmin Hospital of Wuhan University | |
Wuhan, China, 430060 | |
Denmark | |
Aalborg Universitetsshospital | |
Aalborg, Denmark, 9000 | |
Aarhus University Hospital | |
Aarhus N, Denmark, 8200 | |
Rigshospitalet | |
Copenhagen, Denmark, 2100 | |
Frederiksberg Hospital | |
Frederiksberg, Denmark, 2000 | |
Herlev and Gentofte Hospital | |
Herlev, Denmark, 2730 | |
Slagelse Sygehus | |
Slagelse, Denmark, 4200 | |
France | |
HOP Sud Francilien | |
Corbeil Essonnes, France, 91106 | |
HOP CHU de Grenoble | |
Grenoble Cedex 9, France, 38043 | |
CHRU Lille | |
Lille, France, 59037 | |
Hospital de Saint Joseph et Saint Luc | |
Lyon, France, 69007 | |
HOP Bichat | |
Paris, France, 75018 | |
CHU Rouen | |
Rouen Cedex, France, 76031 | |
HOP Trousseau | |
Tours, France, 37044 | |
HOP Brabois | |
Vandoeuvre-lès-Nancy, France, 54511 | |
Germany | |
SLK-Kliniken Heilbronn GmbH | |
Bad Friedrichshall, Germany, 74177 | |
Kerckhoff-Klinik, Bad Nauheim | |
Bad Nauheim, Germany, 61231 | |
Charité - Universitätsmedizin Berlin | |
Berlin, Germany, 12203 | |
Universitätsklinikum Bonn AöR | |
Bonn, Germany, 53127 | |
Bremer Institut für Herz- und Kreislaufforschung (BIHKF) am Klinikum Links der Weser | |
Bremen, Germany, 28277 | |
Klinikum Coburg gGmbH | |
Coburg, Germany, 96450 | |
St. Johannes Hospital Dortmund | |
Dortmund, Germany, 44137 | |
Städtisches Klinikum Dresden | |
Dresden, Germany, 01067 | |
Universitätsklinikum Frankfurt | |
Frankfurt am Main, Germany, 60596 | |
Klinikum Frankfurt Höchst GmbH | |
Frankfurt/Main, Germany, 65929 | |
Universitäts-Herzzentrum Freiburg, Bad Krozingen GmbH | |
Freiburg I. Breisgau, Germany, 79106 | |
Asklepios Kliniken GmbH & Co. KGaA | |
Hamburg, Germany, 22307 | |
Medizinische Hochschule Hannover | |
Hannover, Germany, 30625 | |
Ambulantes Herzzentrum Kassel | |
Kassel, Germany, 34121 | |
Universitätsklinikum Leipzig | |
Leipzig, Germany, 04103 | |
Katholisches Klinikum Mainz | |
Mainz, Germany, 55131 | |
Clemenshospital | |
Münster, Germany, 48153 | |
Kardiologische Praxis Papenburg | |
Papenburg, Germany, 26871 | |
Universitätsklinikum Regensburg | |
Regensburg, Germany, 93053 | |
Hungary | |
Lausmed Kft. Outpatient Unit of Internal Medicine | |
Baja, Hungary, 6500 | |
Buda Hospital of the Hospitaller Order of Saint John of God | |
Budapest, Hungary, 1023 | |
Semmelweis University | |
Budapest, Hungary, 1085 | |
St. Imre Hospital, Budapest | |
Budapest, Hungary, 1115 | |
Semmelweis University | |
Budapest, Hungary, 1122 | |
Magyar Honvedseg Egeszsegugyi Kozpont | |
Budapest, Hungary, 1134 | |
Jahn Ferenc Del-Pest Hospital | |
Budapest, Hungary, 1204 | |
University Debrecen Hospital | |
Debrecen, Hungary, 4032 | |
Csongrad Megyei Eu. Ellato Kozp. Hodmezovasarhely-Mako | |
Hodmezovasarhely, Hungary, 6800 | |
Somogy County Kaposi Mor Teaching Hospital | |
Kaposvar, Hungary, 7400 | |
Bacs-Kiskun Megyei Onkormanyzat Hospital | |
Kecskemet, Hungary, 6000 | |
Pest Megyei Flor Ferenc Hospital | |
Kistarcsa, Hungary, 2143 | |
University of Szeged | |
Szeged, Hungary, 6720 | |
Fejer County Saint George University Teaching Hospital | |
Szekesfehervar, Hungary, 8000 | |
Jasz-Nagykun-Szolnok Megyei Hetenyi G. Korhaz-Rendelointezet | |
Szolnok, Hungary, 5000 | |
Zala County Hospital, Zalaegerszeg | |
Zalaegerszeg, Hungary, 8900 | |
India | |
Kamalnayan Bajaj Hospital | |
Aurangabad, India, 431 010 | |
Sri Jayadeva Institute of Cardiovascular Sciences & Research | |
Bangalore, India, 560069 | |
Narayana Institute of Cardiac Sciences | |
Bangalore, India, 560099 | |
KLES Dr.Prabhakar Kore Hospital and Medical Research Centre | |
Belagavi, India, 590010 | |
Madras Medical Mission, | |
Chennai, India, 600037 | |
Eternal Heart Care Centre & Research Institute Pvt. Ltd. | |
Jaipur, India, 302017 | |
KEM Hospital and Seth G S Medical College | |
Mumbai, India, 400012 | |
Sion Hospital (Lokmanya Tilak Municipal Hospital) | |
Mumbai, India, 400022 | |
Government Medical College & Hospital | |
Nagpur, India, 440009 | |
GB Pant Institute of Post Graduate Medical Education and Research | |
New Delhi, India, 110002 | |
Max Superspeciality Hospital | |
New Delhi, India, 110017 | |
Sir Gangaram Hospital | |
New Delhi, India, 110060 | |
Sahyadri Speciality Hospital | |
Pune, India, 411004 | |
Israel | |
Haemek Medical Center | |
Afula, Israel, 18101 | |
Assuta Medical Center | |
Ashdod, Israel, 77000 | |
Barzilai Medical Center | |
Ashkelon, Israel, 78278 | |
Soroka Univ. Medical Center | |
Beer Sheba, Israel, 8410101 | |
Assaf Harofe Medical Center | |
Beer Yaacov, Israel, 70300 | |
Hillel Yaffe Medical Center, Hadera | |
Hadera, Israel, 38100 | |
Rambam Medical Center | |
Haifa, Israel, 31096 | |
Bnei Zion Medical Center, Haifa | |
Haifa, Israel, 33394 | |
Lady Davis Carmel Medical Center | |
Haifa, Israel, 34362 | |
Hadassah Medical Center, Ein-Karem | |
Jerusalem, Israel, 91000 | |
Shaare Zedek Medical Center, Jerusalem 91031 | |
Jerusalem, Israel, 9103102 | |
Hadassah Medical Center, Ein-Karem | |
Jerusalem, Israel, 91120 | |
Meir Medical Center | |
Kfar-Saba, Israel, 44281 | |
West.Galilee Med.Cent.Naharia | |
Nahariya, Israel, 22100 | |
Rabin Medical Center Beilinson | |
Petah Tikva, Israel, 49100 | |
Rabin Medical Center Beilinson | |
Petah Tikva, Israel, 4941492 | |
The Chaim Sheba Medical Center Tel HaShomer | |
Ramat Gan, Israel, 52621 | |
Kaplan Medical Center | |
Rehovot, Israel, 76100 | |
Ziv Medical Center | |
Safed, Israel, 13100 | |
Sourasky Medical Center | |
Tel Aviv, Israel, 64239 | |
Baruch Padeh Medical Center | |
Tiberias, Israel, 15208 | |
Japan | |
Kasugai Municipal Hospital | |
Aichi, Kasugai, Japan, 486-8510 | |
Toyota Memorial Hospital | |
Aichi, Toyota, Japan, 471-8513 | |
Chibanishi General Hospital | |
Chiba, Matsudo, Japan, 270-2251 | |
Seikeikai New Tokyo Heart Clinic | |
Chiba, Matsudo, Japan, 271-0077 | |
Saiseikai Fukuoka General Hospital | |
Fukuoka, Fukuoka, Japan, 810-0001 | |
Gifu Prefectural General Medical Center | |
Gifu, Gifu, Japan, 500-8717 | |
Ogaki Municipal Hospital | |
Gifu, Ogaki, Japan, 503-8502 | |
Hiroshima General Hospital | |
Hatsukaichi, Japan, 738-8503 | |
Hiroshima Prefectural Hospital | |
Hiroshima, Hiroshima, Japan, 734-8530 | |
Hyogo Brain and Heart Center | |
Hyogo, Himeji, Japan, 670-0981 | |
Ibaraki Prefectural Central Hospital | |
Ibaraki, Kasama, Japan, 309-1793 | |
Tsuchiura Kyodo General Hospital | |
Ibaraki, Tsuchiura, Japan, 300-0028 | |
Ishikawa Prefectural Central Hospital | |
Ishikawa, Kanazawa, Japan, 920-8530 | |
Juntendo University Shizuoka Hospital | |
Izunokuni, Japan, 410-2295 | |
Tokai University Hospital | |
Kanagawa, Isehara, Japan, 259-1193 | |
Sagamihara Kyodo Hospital | |
Kanagawa, Sagamihara, Japan, 252-5188 | |
Yokohama City University Medical Center | |
Kanagawa, Yokohama, Japan, 232-0024 | |
Fukuoka Tokushukai Hospital | |
Kasuga, Japan, 816-0864 | |
Saiseikai Kumamoto Hospital | |
Kumamoto, Kumamoto, Japan, 861-4193 | |
Japanese Red Cross Kumamoto Hospital | |
Kumamoto, Kumamoto, Japan, 861-8520 | |
Kusatsu General Hospital | |
Kusatsu, Japan, 525-8585 | |
Miyazaki Medical Association Hospital | |
Miyazaki, Japan, 880-2102 | |
Nagano Chuo Hospital | |
Nagano, Nagano, Japan, 380-0814 | |
Osaka Police Hospital | |
Osaka, Osaka, Japan, 543-0035 | |
Kagawa Prefectural Central Hospital | |
Takamatsu, Japan, 760-8557 | |
Tokushima Prefectural Central Hospital | |
Tokushima, Japan, 770-0042 | |
St. Luke's International Hospital | |
Tokyo, Chuo-ku, Japan, 104-8560 | |
Tokyo Bay Urayasu Ichikawa Medical Center | |
Urayasu, Japan, 279-0001 | |
Showa University Fujigaoka Hospital | |
Yokohama, Japan, 227-8501 | |
Korea, Republic of | |
Bucheon Sejong Hospital | |
Bucheon, Korea, Republic of, 14754 | |
Pusan National Univ. Hosp | |
Busan, Korea, Republic of, 49241 | |
Chungbuk National University Hospital | |
Cheongiu, Korea, Republic of, 28644 | |
Chungnam National University Hospital | |
Daejoen, Korea, Republic of, 35015 | |
Chonnam National University Hospital | |
Gwangju, Korea, Republic of, 61469 | |
Seoul National University Bundang Hospital | |
Seongnam, Korea, Republic of, 13620 | |
Yonsei University Wonju Severance Christian Hospital | |
Wonju-si, Korea, Republic of, 26426 | |
Netherlands | |
Noordwest Ziekenhuisgroep | |
Alkmaar, Netherlands, 1815 JD | |
Meander Medisch Centrum | |
Amersfoort, Netherlands, 3813 TZ | |
Amsterdam UMC Locatie VUMC | |
Amsterdam, Netherlands, 1081HV | |
Onze Lieve Vrouwe Gasthuis | |
Amsterdam, Netherlands, 1091 HA | |
Rijnstate Hospital | |
Arnhem, Netherlands, 6815 AD | |
Amphia Ziekenhuis | |
Breda, Netherlands, 4819 EV | |
IJsselland Ziekenhuis | |
Capelle Aan Den Ijssel, Netherlands, 2906 ZC | |
Catharina Ziekenhuis | |
Eindhoven, Netherlands, 5623 EJ | |
Medisch Spectrum Twente | |
Enschede, Netherlands, 7513 ER | |
Admiraal de Ruyter Ziekenhuis | |
Goes, Netherlands, 4462 RA | |
Universitair Medisch Centrum Groningen | |
Groningen, Netherlands, 9713 GZ | |
Spaarne Ziekenhuis | |
Haarlem, Netherlands, 2035 RC | |
Zuyderland Medisch Centrum | |
Heerlen, Netherlands, 6419 PC | |
Jeroen Bosch Ziekenhuis-Hertogenbosch | |
Hertogenbosch, Netherlands, 5223 GZ | |
Tergooi Ziekenhuis | |
Hilversum, Netherlands, 1213 XZ | |
Vasculair Onderzoek Centrum | |
Hoorn, Netherlands, 1624 NP | |
Medisch Centrum Leeuwarden | |
Leeuwarden, Netherlands, 8934 AD | |
Leids Universitair Medisch Centrum (LUMC) | |
Leiden, Netherlands, 2300 RC | |
Alrijne Ziekenhuis | |
Leiden, Netherlands, 2334 CK | |
Ziekenhuis Rivierenland | |
Tiel, Netherlands, 4002 WP | |
Tweesteden Ziekenhuis, locatie Tilburg | |
Tilburg, Netherlands, 5042 AD | |
Isala Zwolle | |
Zwolle, Netherlands, 8025 AB | |
Poland | |
American Heart of Poland | |
Belchatow, Poland, 97-400 | |
Univ. Clinic Hosp, Bialystok | |
Bialystok, Poland, 15-276 | |
American Heart of Poland Sp. z o.o. | |
Bielsko-Biala, Poland, 43-316 | |
American-Polish Heart Clinic, Lesser Poland Cardiovascular Centre | |
Chorzow, Poland, 32-500 | |
American Heart of Poland Sp. z o.o. | |
Dabrowa Gornicza, Poland, 41-300 | |
NZOZ Pro-Cordis Sopockie Centrum Bad. Kardiolog. | |
Gdynia, Poland, 81-423 | |
Silesian Medical University in Katowice | |
Katowice, Poland, 40-635 | |
American Heart of Poland Sp. z o.o. | |
Kedzierzyn-Kozle, Poland, 47-200 | |
University Hospital in Krakow | |
Krakow, Poland, 30-688 | |
The John Paul II Hosp.,Dept.of Coronary Heart Disease,Krakow | |
Krakow, Poland, 31-202 | |
Podhalanski Special.Hosp,Intern.Med&Cardiology Dept,Nowy Tag | |
Nowy Targ, Poland, 34-400 | |
Mazowiecki Szpital Specjalistyczny im. dr Jozefa Psarskiego | |
Ostroleka, Poland, 07-410 | |
Medicome Limited Liability Company | |
Oswiecim, Poland, 32-600 | |
Independent Public Healthcare, Dept. of Cardiology, Pulawy | |
Pulawy, Poland, 24-100 | |
American Heart of Poland Sp. z o.o. | |
Sztum, Poland, 82-400 | |
American Heart of Poland Sp. z o.o. | |
Tychy, Poland, 43-100 | |
Dr Alfred Sokołowski Specialist Hospital | |
Walbrzych, Poland, 58-309 | |
Central Hospital of Medical Academy, Warsaw | |
Warsaw, Poland, 02-097 | |
Instytut Kardiologii, Warszawa | |
Warsaw, Poland, 04-628 | |
Jan Mikulicz-Radecki UnivClinic Hosp,Cardiology Dept,Wroclaw | |
Wroclaw, Poland, 50-556 | |
4. Military Clinical Hospital with Polyclinic SP ZOZ | |
Wroclaw, Poland, 50-981 | |
Romania | |
Emergency Clinical County Hospital, Baia Mare | |
Baia Mare, Romania, 430031 | |
Spitalul Clinic De Urgenta "Prof. Dr. Agrippa Ionescu" | |
Balotesti, Romania, 077016 | |
Spitalul Judetean de Urgenta Braila | |
Braila, Romania, 810325 | |
Spitalul Clinic Judetean de Urgenta Brasov | |
Brasov, Romania, 500326 | |
Military Central Clinical Emergency Hospital | |
Bucharest, Romania, 010825 | |
Elias Emergency Hospital, Bucharest | |
Bucharest, Romania, 011461 | |
Prof.C.C.Iliescu Hospital, National Institute of Cardiology | |
Bucharest, Romania, 022322 | |
Emergency Clinical Hospital "Bagdasar-Arseni" | |
Bucharest, Romania, 041915 | |
Emergency University Hospital, Bucharest | |
Bucharest, Romania, 050098 | |
Heart Institute "Niculae Stancioiu", Cluj Napoca | |
Cluj Napoca, Romania, 400001 | |
Clincal Reabilitation Hospital, Cluj Napoca | |
Cluj Napoca, Romania, 400347 | |
Spitalul Clinic Judetean, Craiova | |
Craiova, Romania, 200642 | |
Cardiovascular Diseases Institute "Prof. Georgescu", Iasi | |
Iasi, Romania, 700503 | |
SC Cardiomed SRL, Iasi | |
Iasi, Romania, 700732 | |
SC Endodigest SRL | |
Oradea, Romania, 410151 | |
Sal Med Srl | |
Pitesti, Romania, 110437 | |
Emergency County Clinical Hospital, Sibiu | |
Sibiu, Romania, 550245 | |
Centrul Medical Cardiomed | |
Targu-Mures, Romania, 540124 | |
Country Clinical Emergency Hospital, Targu-Mures | |
Targu-Mures, Romania, 540136 | |
Cardiology and Cardiovascular Rehabilitation Clinic | |
Timisoara, Romania, 300310 | |
Russian Federation | |
First City Clinical Hospital named after E. E. Volosevich | |
Arkhangelsk, Russian Federation, 163001 | |
Regional Clinical Hospital, Kirov | |
Kirov, Russian Federation, 610014 | |
Regional Clinical Hospital No.1 n.a. Ochapovskiy, Krasnodar | |
Krasnodar, Russian Federation, 350086 | |
State Healthcare Institution Clinical Hosp. No. 51, Moscow | |
Moscow, Russian Federation, 121309 | |
Reg.Clin.Hosp.n.a.Semashko | |
Nizhniy Novgorod, Russian Federation, 603126 | |
Penza Regional Clinical Hospital named after N.N.Burdenko | |
Penza, Russian Federation, 440026 | |
Republic Kareliya Republican Hosp. named after V.A. Baranov | |
Petrozavodsk, Russian Federation, 185019 | |
GUZ Ryazanskiy Regional Clin. Cardiology Dispensary, Ryazan | |
Ryazan, Russian Federation, 390039 | |
Samara Regional Clinical Cardiology Clinic, Day Hosp. Dept. | |
Samara, Russian Federation, 443070 | |
Saratov State Med.Univ.n.a.Razumovskogo | |
Saratov, Russian Federation, 410012 | |
Saratov Regional Cardiac Center | |
Saratov, Russian Federation, 410039 | |
Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine | |
St. Petersburg, Russian Federation, 192242 | |
Medical Academy named after I. Mechnikov, St. Petersburg | |
St. Petersburg, Russian Federation, 195067 | |
Komi Republican Cardiological Dispensary | |
Syktyvkar, Russian Federation, 167981 | |
Regional clinical hospital, Tver | |
Tver, Russian Federation, 170036 | |
Tyumen Cardiology Center, Dept.of Cardiac Arrhythmia | |
Tyumen, Russian Federation, 625026 | |
State Budg.Healthc.Instit Volgograd RegClin.Cardiology Centr | |
Volgograd, Russian Federation, 400062 | |
Serbia | |
Institute for Cardiovascular diseases Dedinje | |
Belgrade, Serbia, 11000 | |
University Clinical Center of Serbia | |
Belgrade, Serbia, 11000 | |
Clinical Hospital Center Dr. Dragisa Misovic | |
Belgrade, Serbia, 11040 | |
Clinical Medical Center Zvezdara, Belgrade | |
Belgrade, Serbia, 11050 | |
University Clinical Center of Kragujevac | |
Kragujevac, Serbia, 34000 | |
General Hospital Leskovac | |
Leskovac, Serbia, 16000 | |
Institute for Treatment and Rehabilitation, Niska Banja | |
Niska Banja, Serbia, 18205 | |
University Clinical Center Nis | |
Nis, Serbia, 18000 | |
General Hospital Pancevo | |
Pancevo, Serbia, 26101 | |
Institute of Cardiovascular Diseases | |
Sremska Kamenica, Serbia, 21204 | |
General Hospital Sremska Mitrovica | |
Sremska Mitrovica, Serbia, 22000 | |
General Hospital Subotica, Internal Medicine | |
Subotica, Serbia, 24107 | |
Health Center Uzice | |
Uzice, Serbia, 31000 | |
Health Centre Zajecar | |
Zajecar, Serbia, 19000 | |
General Hospital - Djordje Joanovic | |
Zrenjanin, Serbia, 23101 | |
Spain | |
Hospital Germans Trias i Pujol | |
Badalona, Spain, 08916 | |
University Hospital of Bellvitge | |
Barcelona, Spain, 08907 | |
Hospital Universitario 12 de Octubre | |
Madrid, Spain, 28041 | |
Hospital Universitari Joan XXIII | |
Tarragona, Spain, 43005 | |
Complejo Hospitalario Universitario de Vigo | |
Vigo, Spain, 36213 | |
Ukraine | |
Cherkasy Regional Cardiological Center | |
Cherkasy, Ukraine, 18009 | |
City Joint Emergency Hospital, Dnepropetrovsk | |
Dnepropetrovsk, Ukraine, 49006 | |
Ivano-Frankivsk City Central Clinical Hospital | |
Ivano-Frankivsk, Ukraine, 76005 | |
Clinical Medical Diagnostic Center Simedgroup | |
Ivano-Frankivsk, Ukraine, 76008 | |
L.T. Malaya Institute of Therapy AMS of Ukraine | |
Kharkiv, Ukraine, 61039 | |
Reg.Clin.Hosp.Non-Commercial Enterprise | |
Kharkiv, Ukraine, 61058 | |
CI of Healthcare Kharkiv CCH #8, Kharkiv | |
Kharkiv, Ukraine, 61176 | |
Khmelnytskyi Regional Hospital | |
Khmelnytskyi, Ukraine, 29007 | |
Kiev City Clinical Hospital No. 5 | |
Kiev, Ukraine, 03115 | |
SI NSC M.D. Strazhesko Institute Cardiology of NAMSU, Kyiv | |
Kiev, Ukraine, 03680 | |
City Clinical Hospital No. 1, Kiev | |
Kiev, Ukraine, 2091 | |
Kiev Emergency Care Hospital | |
Kiev, Ukraine, 2166 | |
Lutsk City Clinical Hospital | |
Lutsk, Ukraine, 43024 | |
Communal Noncommercial Enterprise of Lviv Regional Council "Lviv Regional Clinical Psychiatric Hospital" | |
Lviv, Ukraine, 79015 | |
Odesa Regional Clinical Hospital | |
Odesa, Ukraine, 65025 | |
Regional Clinical Hospital, Ternopil | |
Ternopil, Ukraine, 46001 | |
Transcarpathian Regional Clinical Center | |
Uzhgorod, Ukraine, 88000 | |
Zhytomyr Regional Clinical Hospital, Dept. Endocrinology | |
Zhytomyr, Ukraine, 10002 |
Responsible Party: | Boehringer Ingelheim |
ClinicalTrials.gov Identifier: | NCT04509674 |
Other Study ID Numbers: |
1245-0202 2019-001037-13 ( EudraCT Number ) |
First Posted: | August 12, 2020 Key Record Dates |
Last Update Posted: | November 14, 2023 |
Last Verified: | November 2023 |
Individual Participant Data (IPD) Sharing Statement: | |
Plan to Share IPD: | Yes |
Plan Description: | After the study is completed and the primary manuscript is accepted for publishing, researchers can use this following link https://www.mystudywindow.com/msw/datasharing to request access to the clinical study documents regarding this study, and upon a signed "Document Sharing Agreement". Also, Researchers can use the following link https://www.mystudywindow.com/msw/datasharing to find information in order to request access to the clinical study data, for this and other listed studies, after the submission of a research proposal and according to the terms outlined in the website. The data shared are the raw clinical study data sets. |
Supporting Materials: |
Study Protocol Statistical Analysis Plan (SAP) Clinical Study Report (CSR) |
Time Frame: | After all regulatory activities are completed in the US and EU for the product and indication, and after the primary manuscript has been accepted for publication. |
Access Criteria: | For study documents - upon signing of a 'Document Sharing Agreement'. For study data - 1. after the submission and approval of the research proposal (checks will be performed by both the independent review panel and the sponsor, including checking that the planned analysis does not compete with sponsor's publication plan); 2. and upon signing of a 'Data Sharing Agreement'. |
URL: | https://www.mystudywindow.com/msw/datasharing |
Studies a U.S. FDA-regulated Drug Product: | Yes |
Studies a U.S. FDA-regulated Device Product: | No |
Heart Failure Myocardial Infarction Infarction Heart Diseases Cardiovascular Diseases Ischemia Pathologic Processes Necrosis |
Myocardial Ischemia Vascular Diseases Empagliflozin Sodium-Glucose Transporter 2 Inhibitors Molecular Mechanisms of Pharmacological Action Hypoglycemic Agents Physiological Effects of Drugs |