HPV in Sinonasal Ca: Retrospective Analysis Association of Human Papilloma Virus (HPV) Serology and Behavioral Risk Factors
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|ClinicalTrials.gov Identifier: NCT04979000|
Recruitment Status : Recruiting
First Posted : July 27, 2021
Last Update Posted : September 5, 2023
|Condition or disease|
|Sinonasal Carcinoma HPV-Related Squamous Cell Carcinoma|
|Study Type :||Observational|
|Estimated Enrollment :||499 participants|
|Official Title:||The Role of High-risk HPV in Sinonasal Carcinomas: a Retrospective Tissue Analysis of the Increasing Frequency and Case-control Study to Evaluate the Association of HPV Serology and Behavioral Risk Factors|
|Actual Study Start Date :||August 3, 2021|
|Estimated Primary Completion Date :||January 30, 2026|
|Estimated Study Completion Date :||January 30, 2028|
Patients with a confirmed diagnosis of sinonasal cancer.
Patients being seen for benign conditions at Johns Hopkins.
- HPV Status [ Time Frame: Collected at time of surgery or previously conducted biopsy ]High risk HPV present or absent in tumor
- Gender Differences [ Time Frame: completion of the study, approximately 2 years ]Gender differences in HPV-HNSCC risk factors (tobacco, alcohol, drug use and sexual behavior).
- Race/Ethnicity Differences [ Time Frame: completion of the study, approximately 2 years ]Race/ethnicity differences in HPV-HNSCC risk factors (tobacco, alcohol, drug use and sexual behavior).
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT04979000
|Contact: Nyall London, M.D.||firstname.lastname@example.org|
|Contact: Zubair Khan, M.D.||email@example.com|
|Principal Investigator:||Nyall London, M.D.||Department of Otolaryngology and Surgery|