Study of Genetic Differences in People With Depression (Genetics)

• ClinicalTrials.gov Identifier: NCT00229463
• Recruitment Status: Completed
• First Posted: September 29, 2005
• Last Update Posted: November 18, 2016
• Sponsor: University of California, Los Angeles
• Information provided by (Responsible Party): Andrew F. Leuchter, University of California, Los Angeles

Tracking Information

• First Submitted Date: September 28, 2005
• First Posted Date: September 29, 2005
• Last Update Posted Date: November 18, 2016
• Study Start Date: January 2002
• Actual Primary Completion Date: January 2011 (Final data collection date for primary outcome measure)
• Current Primary Outcome Measures: Not Provided
• Original Primary Outcome Measures: Not Provided
• Current Secondary Outcome Measures: Not Provided
• Original Secondary Outcome Measures: Not Provided
• Current Other Pre-specified Outcome Measures: Not Provided
• Original Other Pre-specified Outcome Measures: Not Provided

Descriptive Information

• Brief Title: Study of Genetic Differences in People With Depression
• Official Title: Study of Genetic Differences in People With Depression
• Brief Summary: The purpose of this study is to identify genes involved in depression. Specifically, the investigators will analyze some genes that may be related to whether or not a person responds to antidepressant medication. This project is part of basic scientific research to increase understanding of the role of genetic influences in psychological and mental processes involved in the response to treatment for depression.
• Detailed Description: Not Provided
• Study Type: Observational
• Study Design: Observational Model: Case-Control; Time Perspective: Cross-Sectional
• Target Follow-Up Duration: Not Provided
• Biospecimen: Not Provided
• Sampling Method: Non-Probability Sample
• Study Population: Patients will be recruited from previous studies conducted at the Laboratory of Brain, Behavior, and Pharmacology, where subjects' response to treatment has already been determined. This strategy offers the advantage that no new subjects need to be enrolled in placebo-controlled treatment studies.
• Condition: Depressive Disorder, Major
• Intervention: Not Provided
• Study Groups/Cohorts: Not Provided
• Publications *: Not Provided

Recruitment Information

• Recruitment Status: Completed
• Estimated Enrollment (submitted: September 28, 2005): 200
• Original Enrollment: Same as current
• Actual Study Completion Date: January 2011
• Actual Primary Completion Date: January 2011 (Final data collection date for primary outcome measure)

Eligibility Criteria

Inclusion Criteria:

• History of Unipolar Major Depression
• Control subjects must be healthy normal adults

Exclusion Criteria:

• Subjects with mood symptoms that are not severe enough to qualify for MDD
• Subjects with any active medical illness that may be related to ongoing mood disorder
• Normal subjects must be free from: a psychiatric diagnosis, substance abuse, a history of seizure disorder, and any serious medical illness

Sex/Gender

• Sexes Eligible for Study: All

• Ages: 18 Years to 75 Years (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes
• Contacts: Contact information is only displayed when the study is recruiting subjects
• Listed Location Countries: United States

Administrative Information

• NCT Number: NCT00229463
• Other Study ID Numbers: 01-10-049
• Has Data Monitoring Committee: No
• U.S. FDA-regulated Product: Not Provided
• IPD Sharing Statement: Not Provided
• Current Responsible Party: Andrew F. Leuchter, University of California, Los Angeles
• Original Responsible Party: Not Provided
• Current Study Sponsor: University of California, Los Angeles
• Original Study Sponsor: Same as current
• Collaborators: Not Provided

Investigators

• Principal Investigator: Andrew F. Leuchter, M.D.; University of California, Los Angeles

• PRS Account: University of California, Los Angeles
• Verification Date: October 2016