Time Frame |
Baseline up to Day 2511
|
Adverse Event Reporting Description |
[Not Specified]
|
|
Arm/Group Title
|
Dose Escalation Cohort: Avelumab 1.0 mg/kg
|
Dose Escalation Cohort: Avelumab 3.0 mg/kg
|
Dose Escalation Cohort: Avelumab 10.0 mg/kg
|
Dose Escalation Cohort: Avelumab 20.0 mg/kg
|
Dose Escalation Cohort: Avelumab 10.0 mg/kg Weekly
|
Primary Expansion Cohort: NSCLC, Post-platinum Doublet
|
Primary Expansion Cohort: NSCLC, First Line
|
Primary Expansion Cohort: Metastatic Breast Cancer
|
Primary Expansion Cohort: GC/GEJC Progressed
|
Primary Expansion Cohort: GC/GEJC Non Progressed
|
Secondary Expansion Cohort: Colorectal Cancer
|
Secondary Expansion Cohort: Castrate-resistant Prostate Cancer
|
Secondary Expansion Cohort: Adrenocortical Carcinoma
|
Secondary Expansion Cohort: Melanoma
|
Secondary Expansion Cohort: Mesothelioma
|
Secondary Expansion Cohort: Urothelial Carcinoma
|
Secondary Expansion Cohort: Ovarian Cancer
|
Secondary Expansion Cohort: Renal Cell Carcinoma (First Line)
|
Secondary Expansion Cohort: Renal Cell Carcinoma (Second Line)
|
Efficacy Expansion Cohort: Ovarian Cancer
|
Efficacy Expansion Cohort: Urothelial Carcinoma
|
Efficacy Expansion Cohort: GC/GEJC, Third Line
|
Efficacy Expansion Cohort: HNSCC
|
Arm/Group Description |
Participants with metastatic or loc...
|
Participants with metastatic or loc...
|
Participants with metastatic or loc...
|
Participants with metastatic or loc...
|
Participants with metastatic or loc...
|
Participants with non-small cell lu...
|
Participants with non-small cell lu...
|
Participants with metastatic breast...
|
Participants with gastric and gastr...
|
Participants with gastric and gastr...
|
Participants with colorectal cancer...
|
Participants with castrate-resistan...
|
Participants with adrenocortical ca...
|
Participants with melanoma received...
|
Participants with mesothelioma rece...
|
Participants with urothelial carcin...
|
Participants with ovarian carcinoma...
|
Participants with Renal cell carcin...
|
Participants with Renal cell carcin...
|
Participants with ovarian carcinoma...
|
Participants with urothelial carcin...
|
Participants with gastric (GC) and ...
|
Participants with head and neck squ...
|
Arm/Group Description |
Participants with metastatic or locally advanced solid tumors received intravenous infusion of Avelumab at a dose of 1.0 mg/kg once every 2 weeks in dose escalation cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with metastatic or locally advanced solid tumors received intravenous infusion of Avelumab at a dose of 3.0 milligrams per kilogram (mg/kg) once every 2 weeks in dose escalation cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or investigational medicinal product (IMP) occurs.
|
Participants with metastatic or locally advanced solid tumors received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks in dose escalation cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with metastatic or locally advanced solid tumors received intravenous infusion of Avelumab at a dose of 20.0 mg/kg once every 2 weeks in dose escalation cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with metastatic or locally advanced solid tumors received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once weekly for the first 12 weeks and once every 2 weeks starting Week 13 in dose escalation cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with non-small cell lung cancer (NSCLC), who had progressed after 1 line of platinum-containing doublet chemotherapy received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks in primary expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with non-small cell lung cancer (NSCLC), first line received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks in primary expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with metastatic breast cancer received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks in primary expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with gastric and gastroesophageal cancer who progressed on or after first-line chemotherapy received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks in primary expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with gastric and gastroesophageal cancer who non-progressed on or after first-line chemotherapy received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks in primary expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with colorectal cancer received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks in secondary expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with castrate-resistant prostate cancer received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks in secondary expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with adrenocortical carcinoma received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks in secondary expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with melanoma received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks in secondary expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with mesothelioma received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks in secondary expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with urothelial carcinoma received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks in secondary expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with ovarian carcinoma received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks in secondary expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with Renal cell carcinoma received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks as a first-line therapy in secondary expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with Renal cell carcinoma who failed 1 prior systemic first-line regimen received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks as a second line treatment in secondary expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with ovarian carcinoma received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks in efficacy expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with urothelial carcinoma received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks in efficacy expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with gastric (GC) and gastroesophageal junction cancer (GEJC) who have failed both a first-line chemotherapy regimen and subsequent ramucirumab therapy, received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks as a third-line treatment in efficacy expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
Participants with head and neck squamous cell carcinoma (HNSCC) received intravenous infusion of Avelumab at a dose of 10.0 mg/kg once every 2 weeks in efficacy expansion cohort until confirmed progression, unacceptable toxicity, or any reason for withdrawal from the trial or IMP occurs.
|
|
|
Dose Escalation Cohort: Avelumab 1.0 mg/kg
|
Dose Escalation Cohort: Avelumab 3.0 mg/kg
|
Dose Escalation Cohort: Avelumab 10.0 mg/kg
|
Dose Escalation Cohort: Avelumab 20.0 mg/kg
|
Dose Escalation Cohort: Avelumab 10.0 mg/kg Weekly
|
Primary Expansion Cohort: NSCLC, Post-platinum Doublet
|
Primary Expansion Cohort: NSCLC, First Line
|
Primary Expansion Cohort: Metastatic Breast Cancer
|
Primary Expansion Cohort: GC/GEJC Progressed
|
Primary Expansion Cohort: GC/GEJC Non Progressed
|
Secondary Expansion Cohort: Colorectal Cancer
|
Secondary Expansion Cohort: Castrate-resistant Prostate Cancer
|
Secondary Expansion Cohort: Adrenocortical Carcinoma
|
Secondary Expansion Cohort: Melanoma
|
Secondary Expansion Cohort: Mesothelioma
|
Secondary Expansion Cohort: Urothelial Carcinoma
|
Secondary Expansion Cohort: Ovarian Cancer
|
Secondary Expansion Cohort: Renal Cell Carcinoma (First Line)
|
Secondary Expansion Cohort: Renal Cell Carcinoma (Second Line)
|
Efficacy Expansion Cohort: Ovarian Cancer
|
Efficacy Expansion Cohort: Urothelial Carcinoma
|
Efficacy Expansion Cohort: GC/GEJC, Third Line
|
Efficacy Expansion Cohort: HNSCC
|
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Affected / at Risk (%) |
|
Total |
4/4 (100.00%)
|
|
11/13 (84.62%)
|
|
11/15 (73.33%)
|
|
16/21 (76.19%)
|
|
2/8 (25.00%)
|
|
161/184 (87.50%)
|
|
124/156 (79.49%)
|
|
141/168 (83.93%)
|
|
50/60 (83.33%)
|
|
75/90 (83.33%)
|
|
18/21 (85.71%)
|
|
7/18 (38.89%)
|
|
27/50 (54.00%)
|
|
25/51 (49.02%)
|
|
34/53 (64.15%)
|
|
31/44 (70.45%)
|
|
87/125 (69.60%)
|
|
17/62 (27.42%)
|
|
14/20 (70.00%)
|
|
71/103 (68.93%)
|
|
129/205 (62.93%)
|
|
118/132 (89.39%)
|
|
129/153 (84.31%)
|
|
|
|
Dose Escalation Cohort: Avelumab 1.0 mg/kg
|
Dose Escalation Cohort: Avelumab 3.0 mg/kg
|
Dose Escalation Cohort: Avelumab 10.0 mg/kg
|
Dose Escalation Cohort: Avelumab 20.0 mg/kg
|
Dose Escalation Cohort: Avelumab 10.0 mg/kg Weekly
|
Primary Expansion Cohort: NSCLC, Post-platinum Doublet
|
Primary Expansion Cohort: NSCLC, First Line
|
Primary Expansion Cohort: Metastatic Breast Cancer
|
Primary Expansion Cohort: GC/GEJC Progressed
|
Primary Expansion Cohort: GC/GEJC Non Progressed
|
Secondary Expansion Cohort: Colorectal Cancer
|
Secondary Expansion Cohort: Castrate-resistant Prostate Cancer
|
Secondary Expansion Cohort: Adrenocortical Carcinoma
|
Secondary Expansion Cohort: Melanoma
|
Secondary Expansion Cohort: Mesothelioma
|
Secondary Expansion Cohort: Urothelial Carcinoma
|
Secondary Expansion Cohort: Ovarian Cancer
|
Secondary Expansion Cohort: Renal Cell Carcinoma (First Line)
|
Secondary Expansion Cohort: Renal Cell Carcinoma (Second Line)
|
Efficacy Expansion Cohort: Ovarian Cancer
|
Efficacy Expansion Cohort: Urothelial Carcinoma
|
Efficacy Expansion Cohort: GC/GEJC, Third Line
|
Efficacy Expansion Cohort: HNSCC
|
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Total |
3/4 (75.00%)
|
|
6/13 (46.15%)
|
|
6/15 (40.00%)
|
|
8/21 (38.10%)
|
|
0/8 (0.00%)
|
|
95/184 (51.63%)
|
|
80/156 (51.28%)
|
|
66/168 (39.29%)
|
|
36/60 (60.00%)
|
|
44/90 (48.89%)
|
|
8/21 (38.10%)
|
|
2/18 (11.11%)
|
|
32/50 (64.00%)
|
|
24/51 (47.06%)
|
|
22/53 (41.51%)
|
|
19/44 (43.18%)
|
|
42/125 (33.60%)
|
|
14/62 (22.58%)
|
|
7/20 (35.00%)
|
|
48/103 (46.60%)
|
|
114/205 (55.61%)
|
|
87/132 (65.91%)
|
|
73/153 (47.71%)
|
|
Blood and lymphatic system disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Anaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
0/156 (0.00%)
|
|
3/168 (1.79%)
|
|
3/60 (5.00%)
|
|
3/90 (3.33%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
3/205 (1.46%)
|
|
2/132 (1.52%)
|
|
1/153 (0.65%)
|
|
Autoimmune neutropenia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood loss anaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pancytopenia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Coagulopathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Thrombocytopenia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Leukocytosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Thrombotic microangiopathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cardiac disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Cardiac failure congestive |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Acute coronary syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Atrial fibrillation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
2/51 (3.92%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Cardiac tamponade |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Myocardial infarction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
4/156 (2.56%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pericardial effusion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tachycardia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Cardiac arrest |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Cardiac failure |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cardio-respiratory arrest |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sinus tachycardia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Intracardiac thrombus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cardiac failure chronic |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pericarditis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Acute myocardial infarction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Atrioventricular block |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ventricular fibrillation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Atrial flutter |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bradycardia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
2/21 (9.52%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Myocarditis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Ear and labyrinth disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Vertigo positional |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Endocrine disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Adrenal insufficiency |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypercalcaemia of malignancy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypothyroidism |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Adrenocortical insufficiency acute |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Thyroiditis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hyperthyroidism |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Thyroiditis acute |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Eye disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Ocular retrobulbar haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Retinopathy hypertensive |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vision blurred |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Visual impairment |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Eye pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Gastrointestinal disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Abdominal pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
2/168 (1.19%)
|
|
6/60 (10.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
4/50 (8.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
3/125 (2.40%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
6/103 (5.83%)
|
|
5/205 (2.44%)
|
|
8/132 (6.06%)
|
|
1/153 (0.65%)
|
|
Abdominal pain lower |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Ascites |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
3/60 (5.00%)
|
|
3/90 (3.33%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
3/125 (2.40%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
0/205 (0.00%)
|
|
4/132 (3.03%)
|
|
0/153 (0.00%)
|
|
Constipation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
4/125 (3.20%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
3/132 (2.27%)
|
|
0/153 (0.00%)
|
|
Duodenal obstruction |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Large intestinal obstruction |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nausea |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
2/60 (3.33%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
4/103 (3.88%)
|
|
1/205 (0.49%)
|
|
7/132 (5.30%)
|
|
2/153 (1.31%)
|
|
Vomiting |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
2/60 (3.33%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
2/51 (3.92%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
6/103 (5.83%)
|
|
1/205 (0.49%)
|
|
7/132 (5.30%)
|
|
2/153 (1.31%)
|
|
Abdominal pain upper |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastritis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Incarcerated inguinal hernia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Large intestine perforation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Malignant gastrointestinal obstruction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Colitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastrointestinal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
2/60 (3.33%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
2/51 (3.92%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Ileal perforation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Inflammatory bowel disease |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Abdominal discomfort |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Abdominal distension |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ileus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Obstruction gastric |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
4/132 (3.03%)
|
|
0/153 (0.00%)
|
|
Small intestinal obstruction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
3/90 (3.33%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
6/125 (4.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
5/103 (4.85%)
|
|
4/205 (1.95%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Haematemesis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Intestinal obstruction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
3/125 (2.40%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Melaena |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Oesophageal stenosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Diarrhoea |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
2/103 (1.94%)
|
|
4/205 (1.95%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Dyspepsia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
3/153 (1.96%)
|
|
Subileus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Dysphagia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
3/60 (5.00%)
|
|
5/90 (5.56%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
3/153 (1.96%)
|
|
Oesophagitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Peritoneal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Rectal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Small intestinal perforation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Haemorrhoids |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oesophagitis ulcerative |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastrointestinal pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Haematochezia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Intestinal perforation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pancreatitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pancreatitis acute |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Abdominal wall haematoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Impaired gastric emptying |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Oesophageal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Oesophageal pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Upper gastrointestinal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Gastric haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Mouth haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Strangulated umbilical hernia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Tongue haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Tongue oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
General disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Disease progression |
0/4 (0.00%)
|
|
4/13 (30.77%)
|
|
2/15 (13.33%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
23/184 (12.50%)
|
|
16/156 (10.26%)
|
|
14/168 (8.33%)
|
|
8/60 (13.33%)
|
|
10/90 (11.11%)
|
|
3/21 (14.29%)
|
|
0/18 (0.00%)
|
|
6/50 (12.00%)
|
|
3/51 (5.88%)
|
|
3/53 (5.66%)
|
|
8/44 (18.18%)
|
|
13/125 (10.40%)
|
|
1/62 (1.61%)
|
|
2/20 (10.00%)
|
|
9/103 (8.74%)
|
|
34/205 (16.59%)
|
|
31/132 (23.48%)
|
|
18/153 (11.76%)
|
|
Fatigue |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
2/60 (3.33%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Influenza like illness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Non-cardiac chest pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
4/168 (2.38%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
3/53 (5.66%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Pyrexia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
3/51 (5.88%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
4/205 (1.95%)
|
|
1/132 (0.76%)
|
|
4/153 (2.61%)
|
|
Pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Systemic inflammatory response syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Asthenia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
3/156 (1.92%)
|
|
3/168 (1.79%)
|
|
2/60 (3.33%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
2/51 (3.92%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
3/205 (1.46%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Chest pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Death |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
General physical health deterioration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
3/205 (1.46%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Medical device site pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oedema due to cardiac disease |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gait disturbance |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Chills |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Catheter site pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oedema peripheral |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Generalised oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Localised oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hyperthermia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Complication associated with device |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hepatobiliary disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Cholecystitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cholelithiasis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Autoimmune hepatitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Acute hepatic failure |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bile duct obstruction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cholestasis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hepatic failure |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cholangitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Liver injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Hepatocellular injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Hyperbilirubinaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bile duct stenosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Drug-induced liver injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hepatic function abnormal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cholecystitis acute |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Immune system disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Autoimmune disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
2/15 (13.33%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Anaphylactic reaction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Type I hypersensitivity |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sarcoidosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Infections and infestations |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Pneumonia |
1/4 (25.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
12/184 (6.52%)
|
|
14/156 (8.97%)
|
|
2/168 (1.19%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
4/205 (1.95%)
|
|
4/132 (3.03%)
|
|
3/153 (1.96%)
|
|
Kidney infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Peritonitis bacterial |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Urinary tract infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
3/156 (1.92%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
2/44 (4.55%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
7/205 (3.41%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sepsis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
2/60 (3.33%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
5/205 (2.44%)
|
|
2/132 (1.52%)
|
|
5/153 (3.27%)
|
|
Bronchitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
3/156 (1.92%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Cystitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Septic shock |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urosepsis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
5/205 (2.44%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Appendicitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Aspergillus infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bacterial sepsis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cellulitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
2/153 (1.31%)
|
|
Lung infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
2/153 (1.31%)
|
|
Pulmonary sepsis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Respiratory tract infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Upper respiratory tract infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Arteritis infective |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hepatitis E |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Infected bite |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oral candidiasis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Paronychia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Peritonsillar abscess |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Catheter site infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Escherichia bacteraemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastroenteritis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Lower respiratory tract infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Viral infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Clostridial sepsis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Device related infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Spinal cord infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bacteraemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Gastroenteritis viral |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Perirectal abscess |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Wound infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Pneumonia respiratory syncytial viral |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gallbladder abscess |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pneumonia bacterial |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pyelonephritis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Rhinovirus infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urinary tract infection enterococcal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Clostridium difficile colitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Clostridium difficile infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Cystitis klebsiella |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Diverticulitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Klebsiella bacteraemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Postoperative wound infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Psoas abscess |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sepsis syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Staphylococcal bacteraemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urinary tract infection bacterial |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urinary tract infection fungal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Viral upper respiratory tract infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Herpes zoster |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Abscess |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
H1N1 influenza |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Peritonitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Systemic infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Injury, poisoning and procedural complications |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Infusion related reaction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
4/156 (2.56%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
4/205 (1.95%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Hip fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Post-traumatic pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Radiation necrosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Radiation pneumonitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Subdural haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Thoracic vertebral fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cervical vertebral fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Femoral neck fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Femur fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastrostomy tube site complication |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Humerus fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Spinal compression fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vascular access complication |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Wound complication |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Procedural complication |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Subarachnoid haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Upper limb fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lumbar vertebral fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Overdose |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Post procedural complication |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Fall |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Perirenal haematoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lower limb fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastroenteritis radiation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Rib fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Accidental overdose |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Incorrect dose administered |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Post procedural haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Tibia fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Tracheal obstruction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Investigations |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Blood alkaline phosphatase increased |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Alanine aminotransferase increased |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Amylase increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Aspartate aminotransferase increased |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Electrocardiogram T wave abnormal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood potassium increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
False positive investigation result |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gamma-glutamyltransferase increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Neutrophil count decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Weight decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Transaminases increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood bilirubin increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lipase increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Liver function test increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
General physical condition abnormal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Inflammatory marker increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood creatine phosphokinase increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Electrocardiogram abnormal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood creatine increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
C-reactive protein increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Hepatic enzyme increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Metabolism and nutrition disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Decreased appetite |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Hypokalaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Hyponatraemia |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
2/156 (1.28%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
3/132 (2.27%)
|
|
1/153 (0.65%)
|
|
Hypercalcaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
2/153 (1.31%)
|
|
Dehydration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
4/50 (8.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
3/103 (2.91%)
|
|
5/205 (2.44%)
|
|
3/132 (2.27%)
|
|
0/153 (0.00%)
|
|
Hyperkalaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Hypovolaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Failure to thrive |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hyperglycaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Hypocalcaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypoglycaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Type 1 diabetes mellitus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hyperuricaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Type 2 diabetes mellitus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Metabolic acidosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Malnutrition |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Hypophosphataemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Musculoskeletal and connective tissue disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Myositis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Musculoskeletal chest pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Musculoskeletal pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Back pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
4/168 (2.38%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
4/205 (1.95%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Bone pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pain in extremity |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pathological fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Arthralgia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Muscular weakness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Groin pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Flank pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Myalgia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Spinal pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Osteonecrosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pain in jaw |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Metastases to central nervous system |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Chronic myeloid leukaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Malignant melanoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tumour pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Metastases to spine |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Non-small cell lung cancer metastatic |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Metastases to meninges |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cancer pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Metastases to peripheral nervous system |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Myelodysplastic syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Neoplasm progression |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Laryngeal cancer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Malignant pleural effusion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Tumour invasion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Metastasis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
2/51 (3.92%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tumour compression |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Metastases to bone |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Metastases to ovary |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Leukaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Malignant ascites |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Metastases to liver |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Metastases to peritoneum |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tumour associated fever |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Metastatic gastric cancer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Tumour haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
4/153 (2.61%)
|
|
Tonsil cancer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Gastric cancer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Nervous system disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Seizure |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Embolic stroke |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Encephalopathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Haemorrhage intracranial |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Headache |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Hemiparesis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Monoplegia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Serotonin syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Syncope |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Thecal sac compression |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cerebrovascular accident |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Spinal cord compression |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Vocal cord paralysis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Ataxia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cerebral infarction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hepatic encephalopathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Paraparesis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypoaesthesia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lethargy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Transient ischaemic attack |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Brain injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Posterior reversible encephalopathy syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sensorimotor disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Dizziness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Neuropathy peripheral |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ischaemic stroke |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Carotid artery stenosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Guillain-Barre syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Peripheral motor neuropathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Depressed level of consciousness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Partial seizures |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Epilepsy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Neurotoxicity |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Coma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Product Issues |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Device dislocation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Device malfunction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Psychiatric disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Mental status changes |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hallucination |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Suicide attempt |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Confusional state |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Mood altered |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Completed suicide |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Delirium |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Renal and urinary disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Acute kidney injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
4/50 (8.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
7/205 (3.41%)
|
|
5/132 (3.79%)
|
|
0/153 (0.00%)
|
|
Haematuria |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
7/205 (3.41%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nephrotic syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urinary tract obstruction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Renal disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Renal failure |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bladder spasm |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hydronephrosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Dysuria |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Haemorrhage urinary tract |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ureteric obstruction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urinary incontinence |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nephrolithiasis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Renal ischaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Reproductive system and breast disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Pelvic pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
0 |
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Postmenopausal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vaginal fistula |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Respiratory, thoracic and mediastinal disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Dyspnoea |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
9/184 (4.89%)
|
|
5/156 (3.21%)
|
|
8/168 (4.76%)
|
|
1/60 (1.67%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
4/53 (7.55%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
2/20 (10.00%)
|
|
3/103 (2.91%)
|
|
2/205 (0.98%)
|
|
3/132 (2.27%)
|
|
4/153 (2.61%)
|
|
Dysphonia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypoxia |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
3/156 (1.92%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Pleural effusion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
2/156 (1.28%)
|
|
10/168 (5.95%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
4/125 (3.20%)
|
|
0/62 (0.00%)
|
|
2/20 (10.00%)
|
|
6/103 (5.83%)
|
|
2/205 (0.98%)
|
|
3/132 (2.27%)
|
|
3/153 (1.96%)
|
|
Respiratory failure |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
6/156 (3.85%)
|
|
3/168 (1.79%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
2/205 (0.98%)
|
|
3/132 (2.27%)
|
|
2/153 (1.31%)
|
|
Chronic obstructive pulmonary disease |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
7/184 (3.80%)
|
|
4/156 (2.56%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Acute respiratory failure |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
3/156 (1.92%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Haemoptysis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
3/153 (1.96%)
|
|
Dyspnoea exertional |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Respiratory distress |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Aspiration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Interstitial lung disease |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pneumonitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
2/168 (1.19%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
3/205 (1.46%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Pneumothorax |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
3/156 (1.92%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pneumothorax spontaneous |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pulmonary embolism |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
2/60 (3.33%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
2/44 (4.55%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Acute respiratory distress syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Chylothorax |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cough |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pneumonia aspiration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
5/153 (3.27%)
|
|
Respiratory acidosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pleural fistula |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pleuritic pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Pulmonary arterial hypertension |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pulmonary hypertension |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bronchial obstruction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bronchopneumopathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Respiratory depression |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pulmonary haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lung infiltration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Respiratory arrest |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Epistaxis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Dyspnoea at rest |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Laryngeal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Pharyngeal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Skin and subcutaneous tissue disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Rash generalised |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Rash maculo-papular |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Skin ulcer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Psoriasis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Vascular disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Embolism |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Haematoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypotension |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
2/60 (3.33%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
3/205 (1.46%)
|
|
3/132 (2.27%)
|
|
0/153 (0.00%)
|
|
Jugular vein thrombosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Peripheral arterial occlusive disease |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Peripheral artery thrombosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Peripheral ischaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Deep vein thrombosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Subclavian vein thrombosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ischaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypertension |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Peripheral embolism |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Orthostatic hypotension |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Flushing |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lymphoedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Phlebitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Shock haemorrhagic |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Intermittent claudication |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Term from vocabulary, MedDRA Version 18.1
Indicates events were collected by non-systematic assessment
|
|
Frequency Threshold for Reporting Other Adverse Events
|
0%
|
|
Dose Escalation Cohort: Avelumab 1.0 mg/kg
|
Dose Escalation Cohort: Avelumab 3.0 mg/kg
|
Dose Escalation Cohort: Avelumab 10.0 mg/kg
|
Dose Escalation Cohort: Avelumab 20.0 mg/kg
|
Dose Escalation Cohort: Avelumab 10.0 mg/kg Weekly
|
Primary Expansion Cohort: NSCLC, Post-platinum Doublet
|
Primary Expansion Cohort: NSCLC, First Line
|
Primary Expansion Cohort: Metastatic Breast Cancer
|
Primary Expansion Cohort: GC/GEJC Progressed
|
Primary Expansion Cohort: GC/GEJC Non Progressed
|
Secondary Expansion Cohort: Colorectal Cancer
|
Secondary Expansion Cohort: Castrate-resistant Prostate Cancer
|
Secondary Expansion Cohort: Adrenocortical Carcinoma
|
Secondary Expansion Cohort: Melanoma
|
Secondary Expansion Cohort: Mesothelioma
|
Secondary Expansion Cohort: Urothelial Carcinoma
|
Secondary Expansion Cohort: Ovarian Cancer
|
Secondary Expansion Cohort: Renal Cell Carcinoma (First Line)
|
Secondary Expansion Cohort: Renal Cell Carcinoma (Second Line)
|
Efficacy Expansion Cohort: Ovarian Cancer
|
Efficacy Expansion Cohort: Urothelial Carcinoma
|
Efficacy Expansion Cohort: GC/GEJC, Third Line
|
Efficacy Expansion Cohort: HNSCC
|
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Affected / at Risk (%) |
# Events
|
Total |
4/4 (100.00%)
|
|
13/13 (100.00%)
|
|
15/15 (100.00%)
|
|
21/21 (100.00%)
|
|
8/8 (100.00%)
|
|
178/184 (96.74%)
|
|
152/156 (97.44%)
|
|
159/168 (94.64%)
|
|
58/60 (96.67%)
|
|
86/90 (95.56%)
|
|
20/21 (95.24%)
|
|
17/18 (94.44%)
|
|
50/50 (100.00%)
|
|
50/51 (98.04%)
|
|
53/53 (100.00%)
|
|
44/44 (100.00%)
|
|
122/125 (97.60%)
|
|
62/62 (100.00%)
|
|
19/20 (95.00%)
|
|
102/103 (99.03%)
|
|
202/205 (98.54%)
|
|
125/132 (94.70%)
|
|
143/153 (93.46%)
|
|
Blood and lymphatic system disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Anaemia |
2/4 (50.00%)
|
|
4/13 (30.77%)
|
|
6/15 (40.00%)
|
|
3/21 (14.29%)
|
|
1/8 (12.50%)
|
|
28/184 (15.22%)
|
|
22/156 (14.10%)
|
|
18/168 (10.71%)
|
|
12/60 (20.00%)
|
|
13/90 (14.44%)
|
|
5/21 (23.81%)
|
|
2/18 (11.11%)
|
|
16/50 (32.00%)
|
|
7/51 (13.73%)
|
|
12/53 (22.64%)
|
|
12/44 (27.27%)
|
|
9/125 (7.20%)
|
|
4/62 (6.45%)
|
|
3/20 (15.00%)
|
|
11/103 (10.68%)
|
|
36/205 (17.56%)
|
|
30/132 (22.73%)
|
|
25/153 (16.34%)
|
|
Lymphopenia |
2/4 (50.00%)
|
|
3/13 (23.08%)
|
|
2/15 (13.33%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
3/51 (5.88%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
2/132 (1.52%)
|
|
5/153 (3.27%)
|
|
Thrombocytopenia |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
2/156 (1.28%)
|
|
3/168 (1.79%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
2/132 (1.52%)
|
|
1/153 (0.65%)
|
|
Iron deficiency anaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
9/184 (4.89%)
|
|
4/156 (2.56%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
3/51 (5.88%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
3/205 (1.46%)
|
|
2/132 (1.52%)
|
|
1/153 (0.65%)
|
|
Leukocytosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
1/132 (0.76%)
|
|
5/153 (3.27%)
|
|
Lymph node pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Neutropenia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
2/60 (3.33%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypothrombinaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lymphadenopathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Pancytopenia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Splenic infarction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Thrombocytosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Increased tendency to bruise |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Microcytic anaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lymphatic disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Leukopenia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Anaemia of chronic disease |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hyperchromasia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lymphadenitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Immune thrombocytopenic purpura |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Neutrophilia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Platelet dysfunction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Thrombocytopenic purpura |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Haemorrhagic anaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Cardiac disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Tachycardia |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
2/21 (9.52%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
8/156 (5.13%)
|
|
5/168 (2.98%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
2/21 (9.52%)
|
|
1/18 (5.56%)
|
|
3/50 (6.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
3/125 (2.40%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
6/103 (5.83%)
|
|
3/205 (1.46%)
|
|
2/132 (1.52%)
|
|
2/153 (1.31%)
|
|
Ventricular extrasystoles |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sinus tachycardia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
7/184 (3.80%)
|
|
2/156 (1.28%)
|
|
2/168 (1.19%)
|
|
2/60 (3.33%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
4/50 (8.00%)
|
|
0/51 (0.00%)
|
|
3/53 (5.66%)
|
|
2/44 (4.55%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
3/205 (1.46%)
|
|
2/132 (1.52%)
|
|
2/153 (1.31%)
|
|
Atrial fibrillation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
3/156 (1.92%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Palpitations |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
6/156 (3.85%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Sinus bradycardia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Angina pectoris |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pericardial effusion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
3/168 (1.79%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
2/153 (1.31%)
|
|
Acute left ventricular failure |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Atrial flutter |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cardiac failure congestive |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cardiomyopathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cyanosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Diastolic dysfunction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sinus arrhythmia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Supraventricular tachycardia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tricuspid valve incompetence |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cardiac failure |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Atrial tachycardia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Atrioventricular block first degree |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Atrioventricular block second degree |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bundle branch block |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Left atrial enlargement |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pericarditis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Right atrial enlargement |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Left ventricular failure |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Acute coronary syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Coronary artery disease |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nodal arrhythmia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Conduction disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Arrhythmia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Cardiomegaly |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cardiac tamponade |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Stress cardiomyopathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Coronary artery stenosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Acute myocardial infarction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bundle branch block right |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Heart valve incompetence |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Mitral valve incompetence |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Myocardial ischaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Atrial thrombosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Bundle branch block left |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Cardiac failure chronic |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Bradycardia |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Congenital, familial and genetic disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Hydrocele |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vertebral artery hypoplasia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ear and labyrinth disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Ear discomfort |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Ear pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
3/156 (1.92%)
|
|
4/168 (2.38%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
6/153 (3.92%)
|
|
Ear congestion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tinnitus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
4/205 (1.95%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Vertigo |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
5/156 (3.21%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
3/153 (1.96%)
|
|
Vertigo positional |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Deafness unilateral |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
External ear inflammation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Middle ear inflammation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ear pruritus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Eustachian tube dysfunction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypoacusis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
External ear pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cerumen impaction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Deafness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ear swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Otorrhoea |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Endocrine disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Hypothyroidism |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
3/8 (37.50%)
|
|
16/184 (8.70%)
|
|
16/156 (10.26%)
|
|
12/168 (7.14%)
|
|
2/60 (3.33%)
|
|
3/90 (3.33%)
|
|
1/21 (4.76%)
|
|
3/18 (16.67%)
|
|
11/50 (22.00%)
|
|
3/51 (5.88%)
|
|
4/53 (7.55%)
|
|
3/44 (6.82%)
|
|
11/125 (8.80%)
|
|
7/62 (11.29%)
|
|
1/20 (5.00%)
|
|
5/103 (4.85%)
|
|
7/205 (3.41%)
|
|
5/132 (3.79%)
|
|
14/153 (9.15%)
|
|
Hyperthyroidism |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
4/184 (2.17%)
|
|
5/156 (3.21%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
3/62 (4.84%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Adrenal insufficiency |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Autoimmune thyroiditis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypopituitarism |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Goitre |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypogonadism |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Autoimmune hypothyroidism |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Thyroiditis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Adrenal mass |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cushing's syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Cushingoid |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Diabetes insipidus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hyperparathyroidism |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hyperparathyroidism primary |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Thyroid mass |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypercalcaemia of malignancy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Eye disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Lacrimation increased |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Dry eye |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
2/156 (1.28%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
5/90 (5.56%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
2/125 (1.60%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
4/103 (3.88%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Ocular hyperaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vision blurred |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
6/184 (3.26%)
|
|
4/156 (2.56%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
1/44 (2.27%)
|
|
6/125 (4.80%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
3/153 (1.96%)
|
|
Visual impairment |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Diplopia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Cataract |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Periorbital oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Blindness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cataract nuclear |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Chorioretinal scar |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Conjunctival oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Dermatochalasis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Eye discharge |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Eye swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Eyelid ptosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Glaucoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Iritis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Periorbital swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Pinguecula |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vitreous floaters |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Eye irritation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Asthenopia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ocular discomfort |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Meibomian gland dysfunction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Eye pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
4/153 (2.61%)
|
|
Episcleritis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Conjunctival haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blindness unilateral |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Eyelid oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Visual acuity reduced |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blepharitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Chalazion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Conjunctivitis allergic |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Retinal drusen |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Uveitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Anterior segment ischaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Keratitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Optic neuropathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Periorbital pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Photophobia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Diabetic retinopathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Eyelid skin dryness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Scleral hyperaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Swelling of eyelid |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blepharospasm |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Erythema of eyelid |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Macular degeneration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Conjunctival deposit |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Eye pruritus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Photopsia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Charles Bonnet syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Dry age-related macular degeneration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Ectropion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Exophthalmos |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Noninfective conjunctivitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Gastrointestinal disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Nausea |
1/4 (25.00%)
|
|
2/13 (15.38%)
|
|
6/15 (40.00%)
|
|
2/21 (9.52%)
|
|
1/8 (12.50%)
|
|
55/184 (29.89%)
|
|
47/156 (30.13%)
|
|
50/168 (29.76%)
|
|
18/60 (30.00%)
|
|
20/90 (22.22%)
|
|
6/21 (28.57%)
|
|
2/18 (11.11%)
|
|
21/50 (42.00%)
|
|
10/51 (19.61%)
|
|
12/53 (22.64%)
|
|
12/44 (27.27%)
|
|
31/125 (24.80%)
|
|
20/62 (32.26%)
|
|
4/20 (20.00%)
|
|
33/103 (32.04%)
|
|
56/205 (27.32%)
|
|
31/132 (23.48%)
|
|
29/153 (18.95%)
|
|
Abdominal pain |
1/4 (25.00%)
|
|
2/13 (15.38%)
|
|
2/15 (13.33%)
|
|
2/21 (9.52%)
|
|
2/8 (25.00%)
|
|
14/184 (7.61%)
|
|
11/156 (7.05%)
|
|
17/168 (10.12%)
|
|
8/60 (13.33%)
|
|
21/90 (23.33%)
|
|
3/21 (14.29%)
|
|
0/18 (0.00%)
|
|
10/50 (20.00%)
|
|
7/51 (13.73%)
|
|
6/53 (11.32%)
|
|
10/44 (22.73%)
|
|
30/125 (24.00%)
|
|
8/62 (12.90%)
|
|
1/20 (5.00%)
|
|
31/103 (30.10%)
|
|
30/205 (14.63%)
|
|
29/132 (21.97%)
|
|
8/153 (5.23%)
|
|
Diarrhoea |
1/4 (25.00%)
|
|
1/13 (7.69%)
|
|
3/15 (20.00%)
|
|
3/21 (14.29%)
|
|
1/8 (12.50%)
|
|
40/184 (21.74%)
|
|
35/156 (22.44%)
|
|
0/168 (0.00%)
|
|
9/60 (15.00%)
|
|
12/90 (13.33%)
|
|
5/21 (23.81%)
|
|
5/18 (27.78%)
|
|
14/50 (28.00%)
|
|
14/51 (27.45%)
|
|
11/53 (20.75%)
|
|
13/44 (29.55%)
|
|
31/125 (24.80%)
|
|
21/62 (33.87%)
|
|
6/20 (30.00%)
|
|
25/103 (24.27%)
|
|
40/205 (19.51%)
|
|
12/132 (9.09%)
|
|
26/153 (16.99%)
|
|
Vomiting |
2/4 (50.00%)
|
|
1/13 (7.69%)
|
|
2/15 (13.33%)
|
|
1/21 (4.76%)
|
|
1/8 (12.50%)
|
|
32/184 (17.39%)
|
|
26/156 (16.67%)
|
|
28/168 (16.67%)
|
|
15/60 (25.00%)
|
|
19/90 (21.11%)
|
|
3/21 (14.29%)
|
|
1/18 (5.56%)
|
|
16/50 (32.00%)
|
|
5/51 (9.80%)
|
|
5/53 (9.43%)
|
|
6/44 (13.64%)
|
|
27/125 (21.60%)
|
|
10/62 (16.13%)
|
|
2/20 (10.00%)
|
|
20/103 (19.42%)
|
|
37/205 (18.05%)
|
|
21/132 (15.91%)
|
|
16/153 (10.46%)
|
|
Constipation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
2/15 (13.33%)
|
|
2/21 (9.52%)
|
|
2/8 (25.00%)
|
|
44/184 (23.91%)
|
|
44/156 (28.21%)
|
|
0/168 (0.00%)
|
|
12/60 (20.00%)
|
|
19/90 (21.11%)
|
|
2/21 (9.52%)
|
|
0/18 (0.00%)
|
|
5/50 (10.00%)
|
|
10/51 (19.61%)
|
|
10/53 (18.87%)
|
|
5/44 (11.36%)
|
|
26/125 (20.80%)
|
|
10/62 (16.13%)
|
|
2/20 (10.00%)
|
|
25/103 (24.27%)
|
|
48/205 (23.41%)
|
|
20/132 (15.15%)
|
|
27/153 (17.65%)
|
|
Abdominal distension |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
1/15 (6.67%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
6/184 (3.26%)
|
|
2/156 (1.28%)
|
|
11/168 (6.55%)
|
|
3/60 (5.00%)
|
|
4/90 (4.44%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
19/125 (15.20%)
|
|
6/62 (9.68%)
|
|
1/20 (5.00%)
|
|
10/103 (9.71%)
|
|
0/205 (0.00%)
|
|
4/132 (3.03%)
|
|
0/153 (0.00%)
|
|
Dry mouth |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
5/184 (2.72%)
|
|
6/156 (3.85%)
|
|
5/168 (2.98%)
|
|
1/60 (1.67%)
|
|
4/90 (4.44%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
6/51 (11.76%)
|
|
1/53 (1.89%)
|
|
3/44 (6.82%)
|
|
14/125 (11.20%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
6/103 (5.83%)
|
|
13/205 (6.34%)
|
|
3/132 (2.27%)
|
|
6/153 (3.92%)
|
|
Gastritis |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
1/15 (6.67%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
3/156 (1.92%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Dyspepsia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
2/21 (9.52%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
8/156 (5.13%)
|
|
8/168 (4.76%)
|
|
4/60 (6.67%)
|
|
9/90 (10.00%)
|
|
0/21 (0.00%)
|
|
2/18 (11.11%)
|
|
5/50 (10.00%)
|
|
2/51 (3.92%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
4/125 (3.20%)
|
|
2/62 (3.23%)
|
|
1/20 (5.00%)
|
|
4/103 (3.88%)
|
|
12/205 (5.85%)
|
|
8/132 (6.06%)
|
|
4/153 (2.61%)
|
|
Toothache |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
4/184 (2.17%)
|
|
3/156 (1.92%)
|
|
3/168 (1.79%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Abdominal discomfort |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
3/168 (1.79%)
|
|
2/60 (3.33%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
4/125 (3.20%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Abdominal pain lower |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
3/156 (1.92%)
|
|
2/168 (1.19%)
|
|
1/60 (1.67%)
|
|
2/90 (2.22%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
6/205 (2.93%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Aphthous ulcer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Ascites |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
5/168 (2.98%)
|
|
3/60 (5.00%)
|
|
3/90 (3.33%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
3/51 (5.88%)
|
|
3/53 (5.66%)
|
|
1/44 (2.27%)
|
|
11/125 (8.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
12/103 (11.65%)
|
|
4/205 (1.95%)
|
|
11/132 (8.33%)
|
|
0/153 (0.00%)
|
|
Dental caries |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Dysphagia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
7/184 (3.80%)
|
|
4/156 (2.56%)
|
|
4/168 (2.38%)
|
|
10/60 (16.67%)
|
|
6/90 (6.67%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
2/51 (3.92%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
2/125 (1.60%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
2/103 (1.94%)
|
|
6/205 (2.93%)
|
|
4/132 (3.03%)
|
|
20/153 (13.07%)
|
|
Enteritis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastrooesophageal reflux disease |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
12/184 (6.52%)
|
|
4/156 (2.56%)
|
|
3/168 (1.79%)
|
|
3/60 (5.00%)
|
|
3/90 (3.33%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
4/50 (8.00%)
|
|
1/51 (1.96%)
|
|
3/53 (5.66%)
|
|
2/44 (4.55%)
|
|
5/125 (4.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
11/103 (10.68%)
|
|
5/205 (2.44%)
|
|
3/132 (2.27%)
|
|
3/153 (1.96%)
|
|
Oesophagitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Stomatitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
5/156 (3.21%)
|
|
6/168 (3.57%)
|
|
1/60 (1.67%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
1/51 (1.96%)
|
|
3/53 (5.66%)
|
|
1/44 (2.27%)
|
|
5/125 (4.00%)
|
|
5/62 (8.06%)
|
|
1/20 (5.00%)
|
|
4/103 (3.88%)
|
|
4/205 (1.95%)
|
|
2/132 (1.52%)
|
|
5/153 (3.27%)
|
|
Tongue ulceration |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Flatulence |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
0/156 (0.00%)
|
|
5/168 (2.98%)
|
|
2/60 (3.33%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
4/125 (3.20%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
3/103 (2.91%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Abdominal pain upper |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
5/156 (3.21%)
|
|
0/168 (0.00%)
|
|
6/60 (10.00%)
|
|
12/90 (13.33%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
9/50 (18.00%)
|
|
1/51 (1.96%)
|
|
4/53 (7.55%)
|
|
2/44 (4.55%)
|
|
7/125 (5.60%)
|
|
3/62 (4.84%)
|
|
0/20 (0.00%)
|
|
5/103 (4.85%)
|
|
7/205 (3.41%)
|
|
14/132 (10.61%)
|
|
2/153 (1.31%)
|
|
Odynophagia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
3/153 (1.96%)
|
|
Rectal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Coeliac disease |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Colitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Duodenitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Epigastric discomfort |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Faecaloma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Faeces discoloured |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastric haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastrointestinal pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Gingival pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Gingival ulceration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Haematemesis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Hiatus hernia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lip oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lip swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lower gastrointestinal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Melaena |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
3/90 (3.33%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Oesophageal ulcer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oral pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
3/156 (1.92%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
3/205 (1.46%)
|
|
2/132 (1.52%)
|
|
2/153 (1.31%)
|
|
Paraesthesia oral |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Proctalgia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Retroperitoneal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tongue geographic |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tongue haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tooth disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Haemorrhoids |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
4/156 (2.56%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Anal incontinence |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Diverticulum |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Frequent bowel movements |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gingival swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Haematochezia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Oesophageal pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Oral dysaesthesia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Perianal erythema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Poor dental condition |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Salivary hypersecretion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
2/153 (1.31%)
|
|
Abdominal tenderness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
3/168 (1.79%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cheilitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Abdominal rigidity |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Breath odour |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Faeces hard |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Glossitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypoaesthesia oral |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Mouth ulceration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
2/153 (1.31%)
|
|
Retching |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Swollen tongue |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Tongue blistering |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Eructation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Gastric ulcer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastrointestinal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gingival bleeding |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Impaired gastric emptying |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
4/132 (3.03%)
|
|
0/153 (0.00%)
|
|
Intestinal obstruction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Obstruction gastric |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oesophageal obstruction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oesophageal stenosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pancreatitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Peptic ulcer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Rectal tenesmus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Salivary gland mass |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Anal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Aptyalism |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Noninfective sialoadenitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lip blister |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Subileus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Anorectal discomfort |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Glossodynia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Portal hypertensive gastropathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Varices oesophageal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastrointestinal sounds abnormal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Large intestine polyp |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lip pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Food poisoning |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastrointestinal inflammation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ileus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Lip dry |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Enterocutaneous fistula |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Faeces soft |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Functional gastrointestinal disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Large intestinal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Noninfective gingivitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Rectal discharge |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Anal pruritus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastrointestinal disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Inguinal hernia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Abdominal mass |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bowel movement irregularity |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Diarrhoea haemorrhagic |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tongue discomfort |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Abdominal hernia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Umbilical hernia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Mucous stools |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Autoimmune colitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Chronic gastritis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Defaecation urgency |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Diverticulum intestinal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Enterocolitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gingival disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Lip ulceration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Mouth cyst |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oral disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Oral mucosal blistering |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pancreatic duct dilatation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pancreatitis acute |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastrointestinal fistula |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Oesophageal fistula |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Mouth haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
3/153 (1.96%)
|
|
Tongue oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Mouth swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Regurgitation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Salivary gland pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Tongue necrosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Haemorrhoidal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
General disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Fatigue |
2/4 (50.00%)
|
|
7/13 (53.85%)
|
|
13/15 (86.67%)
|
|
6/21 (28.57%)
|
|
3/8 (37.50%)
|
|
74/184 (40.22%)
|
|
71/156 (45.51%)
|
|
66/168 (39.29%)
|
|
13/60 (21.67%)
|
|
20/90 (22.22%)
|
|
5/21 (23.81%)
|
|
7/18 (38.89%)
|
|
17/50 (34.00%)
|
|
13/51 (25.49%)
|
|
17/53 (32.08%)
|
|
17/44 (38.64%)
|
|
36/125 (28.80%)
|
|
27/62 (43.55%)
|
|
10/20 (50.00%)
|
|
38/103 (36.89%)
|
|
72/205 (35.12%)
|
|
37/132 (28.03%)
|
|
41/153 (26.80%)
|
|
Pyrexia |
4/4 (100.00%)
|
|
2/13 (15.38%)
|
|
4/15 (26.67%)
|
|
4/21 (19.05%)
|
|
0/8 (0.00%)
|
|
19/184 (10.33%)
|
|
20/156 (12.82%)
|
|
20/168 (11.90%)
|
|
7/60 (11.67%)
|
|
6/90 (6.67%)
|
|
4/21 (19.05%)
|
|
2/18 (11.11%)
|
|
15/50 (30.00%)
|
|
5/51 (9.80%)
|
|
8/53 (15.09%)
|
|
6/44 (13.64%)
|
|
10/125 (8.00%)
|
|
10/62 (16.13%)
|
|
2/20 (10.00%)
|
|
16/103 (15.53%)
|
|
33/205 (16.10%)
|
|
21/132 (15.91%)
|
|
31/153 (20.26%)
|
|
Influenza like illness |
1/4 (25.00%)
|
|
1/13 (7.69%)
|
|
4/15 (26.67%)
|
|
7/21 (33.33%)
|
|
0/8 (0.00%)
|
|
9/184 (4.89%)
|
|
5/156 (3.21%)
|
|
14/168 (8.33%)
|
|
0/60 (0.00%)
|
|
5/90 (5.56%)
|
|
2/21 (9.52%)
|
|
3/18 (16.67%)
|
|
3/50 (6.00%)
|
|
2/51 (3.92%)
|
|
1/53 (1.89%)
|
|
2/44 (4.55%)
|
|
8/125 (6.40%)
|
|
4/62 (6.45%)
|
|
1/20 (5.00%)
|
|
5/103 (4.85%)
|
|
6/205 (2.93%)
|
|
3/132 (2.27%)
|
|
6/153 (3.92%)
|
|
Chills |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
2/15 (13.33%)
|
|
2/21 (9.52%)
|
|
1/8 (12.50%)
|
|
22/184 (11.96%)
|
|
15/156 (9.62%)
|
|
8/168 (4.76%)
|
|
3/60 (5.00%)
|
|
6/90 (6.67%)
|
|
1/21 (4.76%)
|
|
2/18 (11.11%)
|
|
7/50 (14.00%)
|
|
9/51 (17.65%)
|
|
11/53 (20.75%)
|
|
6/44 (13.64%)
|
|
11/125 (8.80%)
|
|
9/62 (14.52%)
|
|
0/20 (0.00%)
|
|
16/103 (15.53%)
|
|
18/205 (8.78%)
|
|
15/132 (11.36%)
|
|
14/153 (9.15%)
|
|
Oedema peripheral |
1/4 (25.00%)
|
|
2/13 (15.38%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
1/8 (12.50%)
|
|
26/184 (14.13%)
|
|
27/156 (17.31%)
|
|
17/168 (10.12%)
|
|
1/60 (1.67%)
|
|
2/90 (2.22%)
|
|
2/21 (9.52%)
|
|
1/18 (5.56%)
|
|
11/50 (22.00%)
|
|
7/51 (13.73%)
|
|
7/53 (13.21%)
|
|
7/44 (15.91%)
|
|
25/125 (20.00%)
|
|
6/62 (9.68%)
|
|
2/20 (10.00%)
|
|
21/103 (20.39%)
|
|
31/205 (15.12%)
|
|
21/132 (15.91%)
|
|
7/153 (4.58%)
|
|
Malaise |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
6/184 (3.26%)
|
|
7/156 (4.49%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
0/50 (0.00%)
|
|
2/51 (3.92%)
|
|
1/53 (1.89%)
|
|
2/44 (4.55%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
3/205 (1.46%)
|
|
2/132 (1.52%)
|
|
1/153 (0.65%)
|
|
Peripheral swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
2/8 (25.00%)
|
|
3/184 (1.63%)
|
|
3/156 (1.92%)
|
|
6/168 (3.57%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
3/44 (6.82%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
4/103 (3.88%)
|
|
4/205 (1.95%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Asthenia |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
11/184 (5.98%)
|
|
13/156 (8.33%)
|
|
15/168 (8.93%)
|
|
5/60 (8.33%)
|
|
8/90 (8.89%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
7/50 (14.00%)
|
|
7/51 (13.73%)
|
|
9/53 (16.98%)
|
|
8/44 (18.18%)
|
|
0/125 (0.00%)
|
|
12/62 (19.35%)
|
|
2/20 (10.00%)
|
|
6/103 (5.83%)
|
|
25/205 (12.20%)
|
|
11/132 (8.33%)
|
|
19/153 (12.42%)
|
|
Chest pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
1/184 (0.54%)
|
|
3/156 (1.92%)
|
|
7/168 (4.17%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
2/53 (3.77%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
2/20 (10.00%)
|
|
0/103 (0.00%)
|
|
4/205 (1.95%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Facial pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
4/153 (2.61%)
|
|
Injection site reaction |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Mucosal inflammation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Non-cardiac chest pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
15/184 (8.15%)
|
|
12/156 (7.69%)
|
|
9/168 (5.36%)
|
|
2/60 (3.33%)
|
|
5/90 (5.56%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
5/50 (10.00%)
|
|
1/51 (1.96%)
|
|
5/53 (9.43%)
|
|
2/44 (4.55%)
|
|
5/125 (4.00%)
|
|
4/62 (6.45%)
|
|
2/20 (10.00%)
|
|
9/103 (8.74%)
|
|
4/205 (1.95%)
|
|
6/132 (4.55%)
|
|
5/153 (3.27%)
|
|
Pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
7/184 (3.80%)
|
|
7/156 (4.49%)
|
|
7/168 (4.17%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
1/51 (1.96%)
|
|
3/53 (5.66%)
|
|
3/44 (6.82%)
|
|
5/125 (4.00%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
3/132 (2.27%)
|
|
4/153 (2.61%)
|
|
Gait disturbance |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
2/156 (1.28%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
4/132 (3.03%)
|
|
2/153 (1.31%)
|
|
Axillary pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
0/156 (0.00%)
|
|
3/168 (1.79%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Catheter site pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
0/156 (0.00%)
|
|
4/168 (2.38%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Feeling cold |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Localised oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
3/125 (2.40%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Chest discomfort |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
5/156 (3.21%)
|
|
4/168 (2.38%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Discomfort |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Early satiety |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Face oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
2/132 (1.52%)
|
|
8/153 (5.23%)
|
|
Feeling hot |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nodule |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Temperature intolerance |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Adverse drug reaction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cyst |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Feeling jittery |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Inflammation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Infusion site extravasation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
2/153 (1.31%)
|
|
Polyp |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Secretion discharge |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Disease progression |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
3/132 (2.27%)
|
|
0/153 (0.00%)
|
|
Administration site extravasation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Catheter site erythema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
General physical health deterioration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
1/132 (0.76%)
|
|
3/153 (1.96%)
|
|
Injection site pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Mass |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Medical device site pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Medical device site rash |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oedema due to cardiac disease |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Performance status decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Xerosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Crying |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Generalised oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Catheter site swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Catheter site warmth |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Local swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Medical device pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Thirst |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Administration site erythema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Catheter site extravasation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Catheter site haematoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Infusion site swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Drug intolerance |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Granuloma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Implant site pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Catheter site dermatitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Catheter site haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Catheter site rash |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Catheter site inflammation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Complication associated with device |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Gait deviation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hernia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Injection site pruritus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Suprapubic pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Systemic inflammatory response syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypothermia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Medical device site erythema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Hyperthermia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Injection site oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hepatobiliary disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Biliary dilatation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cholelithiasis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Cholecystitis acute |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cholecystitis chronic |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Autoimmune hepatitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
3/168 (1.79%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hepatomegaly |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bile duct obstruction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hepatic pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Hyperbilirubinaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Liver disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hepatocellular injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
4/153 (2.61%)
|
|
Cholangitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cholestasis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Cholecystitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Drug-induced liver injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hepatic steatosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hepatitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ischaemic hepatitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Immune system disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Hypersensitivity |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Seasonal allergy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
3/156 (1.92%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Contrast media reaction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Drug hypersensitivity |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
3/156 (1.92%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Autoimmune disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Type IV hypersensitivity reaction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Contrast media allergy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
3/62 (4.84%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Anaphylactic reaction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Infections and infestations |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upper respiratory tract infection |
1/4 (25.00%)
|
|
2/13 (15.38%)
|
|
2/15 (13.33%)
|
|
2/21 (9.52%)
|
|
2/8 (25.00%)
|
|
21/184 (11.41%)
|
|
21/156 (13.46%)
|
|
5/168 (2.98%)
|
|
0/60 (0.00%)
|
|
8/90 (8.89%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
4/50 (8.00%)
|
|
5/51 (9.80%)
|
|
6/53 (11.32%)
|
|
2/44 (4.55%)
|
|
11/125 (8.80%)
|
|
7/62 (11.29%)
|
|
1/20 (5.00%)
|
|
7/103 (6.80%)
|
|
12/205 (5.85%)
|
|
2/132 (1.52%)
|
|
10/153 (6.54%)
|
|
Pneumonia |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
15/184 (8.15%)
|
|
9/156 (5.77%)
|
|
3/168 (1.79%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
5/125 (4.00%)
|
|
4/62 (6.45%)
|
|
1/20 (5.00%)
|
|
2/103 (1.94%)
|
|
5/205 (2.44%)
|
|
2/132 (1.52%)
|
|
7/153 (4.58%)
|
|
Urinary tract infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
2/21 (9.52%)
|
|
1/8 (12.50%)
|
|
19/184 (10.33%)
|
|
14/156 (8.97%)
|
|
17/168 (10.12%)
|
|
2/60 (3.33%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
4/50 (8.00%)
|
|
7/51 (13.73%)
|
|
3/53 (5.66%)
|
|
7/44 (15.91%)
|
|
21/125 (16.80%)
|
|
8/62 (12.90%)
|
|
2/20 (10.00%)
|
|
18/103 (17.48%)
|
|
47/205 (22.93%)
|
|
6/132 (4.55%)
|
|
8/153 (5.23%)
|
|
Conjunctivitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
2/21 (9.52%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
6/62 (9.68%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hordeolum |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
1/8 (12.50%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bronchitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
13/184 (7.07%)
|
|
15/156 (9.62%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
3/125 (2.40%)
|
|
2/62 (3.23%)
|
|
2/20 (10.00%)
|
|
1/103 (0.97%)
|
|
6/205 (2.93%)
|
|
1/132 (0.76%)
|
|
6/153 (3.92%)
|
|
Enterocolitis viral |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Localised infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Otitis media |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sinusitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
6/184 (3.26%)
|
|
3/156 (1.92%)
|
|
2/168 (1.19%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
1/44 (2.27%)
|
|
4/125 (3.20%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
4/205 (1.95%)
|
|
1/132 (0.76%)
|
|
5/153 (3.27%)
|
|
Sinusitis bacterial |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
4/168 (2.38%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Staphylococcal infection |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Viral upper respiratory tract infection |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
8/90 (8.89%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
2/44 (4.55%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oral candidiasis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
6/156 (3.85%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
2/51 (3.92%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
3/125 (2.40%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
6/205 (2.93%)
|
|
3/132 (2.27%)
|
|
4/153 (2.61%)
|
|
Herpes zoster |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
4/156 (2.56%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
2/51 (3.92%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
2/205 (0.98%)
|
|
2/132 (1.52%)
|
|
1/153 (0.65%)
|
|
Nasopharyngitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
6/156 (3.85%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
9/50 (18.00%)
|
|
4/51 (7.84%)
|
|
1/53 (1.89%)
|
|
2/44 (4.55%)
|
|
2/125 (1.60%)
|
|
8/62 (12.90%)
|
|
2/20 (10.00%)
|
|
1/103 (0.97%)
|
|
6/205 (2.93%)
|
|
0/132 (0.00%)
|
|
4/153 (2.61%)
|
|
Tooth infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
3/153 (1.96%)
|
|
Abscess limb |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Candida infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Gastroenteritis viral |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lower respiratory tract infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Lung infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
6/156 (3.85%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
2/153 (1.31%)
|
|
Asymptomatic bacteriuria |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bacterial disease carrier |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bacteriuria |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Chest wall abscess |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Clostridium difficile infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Cystitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
4/205 (1.95%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Ear infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Eye infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Fungal infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Furuncle |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Helicobacter infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Influenza |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
3/62 (4.84%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Lung abscess |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Mucosal infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nail infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oral fungal infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Oral infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Pharyngitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pharyngitis streptococcal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Rash pustular |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
2/44 (4.55%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Respiratory tract infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Skin candida |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Stenotrophomonas infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tooth abscess |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Vaginal infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vulval abscess |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Vulvovaginal mycotic infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
3/125 (2.40%)
|
|
0/62 (0.00%)
|
|
2/20 (10.00%)
|
|
2/103 (1.94%)
|
|
2/205 (0.98%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Cellulitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
4/156 (2.56%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
2/44 (4.55%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
4/205 (1.95%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Skin infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
3/156 (1.92%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
2/153 (1.31%)
|
|
Erysipelas |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Fungal skin infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Arteritis infective |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Atypical pneumonia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bacteraemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cystitis klebsiella |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Fungal oesophagitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastroenteritis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Herpes simplex |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Infected dermal cyst |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Labyrinthitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Laryngitis viral |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Mycobacterial infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oral herpes |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Rhinitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
4/62 (6.45%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
5/153 (3.27%)
|
|
Sputum purulent |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Viral infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Onychomycosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Angular cheilitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Bacterial rhinitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Device related infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Impetigo |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Tongue fungal infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tracheitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Acarodermatitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Diverticulitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Endophthalmitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Fungal pharyngitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gingivitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Laryngitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lice infestation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Periodontitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tonsillitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vestibulitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Viral rhinitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Abscess neck |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bacterial sepsis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastrointestinal infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Haemophilus infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Herpes virus infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Myringitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oesophageal candidiasis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Folliculitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
2/51 (3.92%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Body tinea |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Osteomyelitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pulpitis dental |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tinea versicolour |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Trichomoniasis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Wound infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Conjunctivitis viral |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tinea infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Abdominal abscess |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Acute sinusitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Lip infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Penile infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Perirectal abscess |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sepsis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Abdominal infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Genital infection female |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Anal abscess |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bronchitis viral |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Catheter site infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Mastitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Molluscum contagiosum |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Diarrhoea infectious |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastrointestinal viral infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Clostridium difficile colitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Coccidioidomycosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pyelonephritis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pyuria |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Stoma site infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Urinary tract infection bacterial |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Herpes dermatitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Infected skin ulcer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Kidney infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Paronychia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pelvic abscess |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pneumonia cytomegaloviral |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Septic shock |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tinea pedis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urinary tract infection enterococcal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urinary tract infection fungal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Empyema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Endocarditis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Escherichia urinary tract infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Meningitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Stoma site cellulitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Vascular device infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Beta haemolytic streptococcal infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Clostridium colitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Enterocolitis infectious |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Gingival abscess |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Medical device site infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Ophthalmic herpes zoster |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Purulent discharge |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Upper respiratory fungal infection |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Abscess |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Device related sepsis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Injury, poisoning and procedural complications |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Infusion related reaction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
3/21 (14.29%)
|
|
4/8 (50.00%)
|
|
35/184 (19.02%)
|
|
25/156 (16.03%)
|
|
24/168 (14.29%)
|
|
6/60 (10.00%)
|
|
13/90 (14.44%)
|
|
6/21 (28.57%)
|
|
4/18 (22.22%)
|
|
6/50 (12.00%)
|
|
12/51 (23.53%)
|
|
19/53 (35.85%)
|
|
9/44 (20.45%)
|
|
17/125 (13.60%)
|
|
12/62 (19.35%)
|
|
5/20 (25.00%)
|
|
17/103 (16.50%)
|
|
47/205 (22.93%)
|
|
18/132 (13.64%)
|
|
13/153 (8.50%)
|
|
Fall |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
8/184 (4.35%)
|
|
12/156 (7.69%)
|
|
6/168 (3.57%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
1/51 (1.96%)
|
|
3/53 (5.66%)
|
|
4/44 (9.09%)
|
|
3/125 (2.40%)
|
|
1/62 (1.61%)
|
|
2/20 (10.00%)
|
|
7/103 (6.80%)
|
|
9/205 (4.39%)
|
|
5/132 (3.79%)
|
|
8/153 (5.23%)
|
|
Procedural pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
1/184 (0.54%)
|
|
4/156 (2.56%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Contusion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
5/156 (3.21%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
1/51 (1.96%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
5/125 (4.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
1/205 (0.49%)
|
|
3/132 (2.27%)
|
|
0/153 (0.00%)
|
|
Spinal compression fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Animal bite |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Foot fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Incision site pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Muscle strain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Skin laceration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
4/156 (2.56%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Vascular access complication |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ear injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypobarism |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Limb injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Procedural anxiety |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Procedural haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Radiation necrosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Radiation pneumonitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Radius fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Rib fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
4/156 (2.56%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Upper limb fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Eschar |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Skin abrasion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Anaemia postoperative |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Brain contusion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Burn oesophageal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cartilage injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Incision site haematoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Jaw fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Ligament sprain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Post-thoracotomy pain syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Post-traumatic pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Skin wound |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Skull fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Spinal fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Thoracic vertebral fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
VIIth nerve injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Wound |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Incision site complication |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Joint injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Laceration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Traumatic haematoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Wound secretion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Excoriation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Arthropod bite |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lumbar vertebral fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Radiation injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urostomy complication |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cervical vertebral fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Face injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Chest injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Joint dislocation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Radiation retinopathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Radiation skin injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Stoma site pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Perineal injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Humerus fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Testicular injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pneumothorax traumatic |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Stoma site haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Thermal burn |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Sunburn |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tendon rupture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Post procedural inflammation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lip injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Facial bones fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Clavicle fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Concussion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Subdural haematoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastrostomy tube site complication |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Hand fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Meniscus injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Tooth fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Accidental overdose |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Confusion postoperative |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Foreign body in eye |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Fractured sacrum |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Incision site pruritus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lower limb fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Seroma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Stoma site pruritus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Suture related complication |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bite |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Radiation associated pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Epicondylitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Eye injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Head injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Post procedural complication |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Procedural hypotension |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Procedural nausea |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Radiation fibrosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Skin injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Stoma complication |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Investigations |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Aspartate aminotransferase increased |
2/4 (50.00%)
|
|
2/13 (15.38%)
|
|
1/15 (6.67%)
|
|
5/21 (23.81%)
|
|
1/8 (12.50%)
|
|
4/184 (2.17%)
|
|
4/156 (2.56%)
|
|
14/168 (8.33%)
|
|
3/60 (5.00%)
|
|
10/90 (11.11%)
|
|
5/21 (23.81%)
|
|
2/18 (11.11%)
|
|
7/50 (14.00%)
|
|
3/51 (5.88%)
|
|
3/53 (5.66%)
|
|
4/44 (9.09%)
|
|
5/125 (4.00%)
|
|
3/62 (4.84%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
15/205 (7.32%)
|
|
19/132 (14.39%)
|
|
5/153 (3.27%)
|
|
Weight decreased |
1/4 (25.00%)
|
|
1/13 (7.69%)
|
|
5/15 (33.33%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
27/184 (14.67%)
|
|
45/156 (28.85%)
|
|
13/168 (7.74%)
|
|
21/60 (35.00%)
|
|
19/90 (21.11%)
|
|
3/21 (14.29%)
|
|
1/18 (5.56%)
|
|
9/50 (18.00%)
|
|
8/51 (15.69%)
|
|
10/53 (18.87%)
|
|
15/44 (34.09%)
|
|
22/125 (17.60%)
|
|
3/62 (4.84%)
|
|
3/20 (15.00%)
|
|
18/103 (17.48%)
|
|
36/205 (17.56%)
|
|
22/132 (16.67%)
|
|
34/153 (22.22%)
|
|
Weight increased |
0/4 (0.00%)
|
|
3/13 (23.08%)
|
|
0/15 (0.00%)
|
|
3/21 (14.29%)
|
|
1/8 (12.50%)
|
|
13/184 (7.07%)
|
|
9/156 (5.77%)
|
|
2/168 (1.19%)
|
|
2/60 (3.33%)
|
|
4/90 (4.44%)
|
|
1/21 (4.76%)
|
|
1/18 (5.56%)
|
|
8/50 (16.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
7/44 (15.91%)
|
|
11/125 (8.80%)
|
|
2/62 (3.23%)
|
|
2/20 (10.00%)
|
|
8/103 (7.77%)
|
|
8/205 (3.90%)
|
|
3/132 (2.27%)
|
|
2/153 (1.31%)
|
|
White blood cell count decreased |
1/4 (25.00%)
|
|
2/13 (15.38%)
|
|
3/15 (20.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
2/21 (9.52%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
2/153 (1.31%)
|
|
Alanine aminotransferase increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
3/21 (14.29%)
|
|
1/8 (12.50%)
|
|
3/184 (1.63%)
|
|
7/156 (4.49%)
|
|
11/168 (6.55%)
|
|
2/60 (3.33%)
|
|
7/90 (7.78%)
|
|
4/21 (19.05%)
|
|
2/18 (11.11%)
|
|
9/50 (18.00%)
|
|
2/51 (3.92%)
|
|
2/53 (3.77%)
|
|
2/44 (4.55%)
|
|
4/125 (3.20%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
8/205 (3.90%)
|
|
10/132 (7.58%)
|
|
5/153 (3.27%)
|
|
Blood alkaline phosphatase increased |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
1/15 (6.67%)
|
|
2/21 (9.52%)
|
|
1/8 (12.50%)
|
|
2/184 (1.09%)
|
|
3/156 (1.92%)
|
|
7/168 (4.17%)
|
|
4/60 (6.67%)
|
|
3/90 (3.33%)
|
|
7/21 (33.33%)
|
|
1/18 (5.56%)
|
|
5/50 (10.00%)
|
|
2/51 (3.92%)
|
|
2/53 (3.77%)
|
|
2/44 (4.55%)
|
|
3/125 (2.40%)
|
|
1/62 (1.61%)
|
|
2/20 (10.00%)
|
|
3/103 (2.91%)
|
|
14/205 (6.83%)
|
|
11/132 (8.33%)
|
|
3/153 (1.96%)
|
|
Blood creatine phosphokinase increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
3/21 (14.29%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
4/156 (2.56%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
4/90 (4.44%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
2/44 (4.55%)
|
|
3/125 (2.40%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Blood creatinine increased |
2/4 (50.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
2/21 (9.52%)
|
|
0/8 (0.00%)
|
|
7/184 (3.80%)
|
|
11/156 (7.05%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
1/21 (4.76%)
|
|
2/18 (11.11%)
|
|
7/50 (14.00%)
|
|
0/51 (0.00%)
|
|
4/53 (7.55%)
|
|
4/44 (9.09%)
|
|
3/125 (2.40%)
|
|
7/62 (11.29%)
|
|
2/20 (10.00%)
|
|
10/103 (9.71%)
|
|
22/205 (10.73%)
|
|
6/132 (4.55%)
|
|
2/153 (1.31%)
|
|
Lipase increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
4/21 (19.05%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
8/156 (5.13%)
|
|
0/168 (0.00%)
|
|
2/60 (3.33%)
|
|
2/90 (2.22%)
|
|
3/21 (14.29%)
|
|
1/18 (5.56%)
|
|
4/50 (8.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
4/125 (3.20%)
|
|
8/62 (12.90%)
|
|
3/20 (15.00%)
|
|
2/103 (1.94%)
|
|
6/205 (2.93%)
|
|
2/132 (1.52%)
|
|
2/153 (1.31%)
|
|
Lymphocyte count decreased |
0/4 (0.00%)
|
|
2/13 (15.38%)
|
|
2/15 (13.33%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
6/168 (3.57%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
7/21 (33.33%)
|
|
0/18 (0.00%)
|
|
5/50 (10.00%)
|
|
0/51 (0.00%)
|
|
7/53 (13.21%)
|
|
3/44 (6.82%)
|
|
3/125 (2.40%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
5/103 (4.85%)
|
|
3/205 (1.46%)
|
|
4/132 (3.03%)
|
|
7/153 (4.58%)
|
|
Amylase increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
2/21 (9.52%)
|
|
1/8 (12.50%)
|
|
5/184 (2.72%)
|
|
6/156 (3.85%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
2/90 (2.22%)
|
|
1/21 (4.76%)
|
|
2/18 (11.11%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
3/125 (2.40%)
|
|
1/62 (1.61%)
|
|
2/20 (10.00%)
|
|
3/103 (2.91%)
|
|
6/205 (2.93%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Gamma-glutamyltransferase increased |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
5/156 (3.21%)
|
|
6/168 (3.57%)
|
|
1/60 (1.67%)
|
|
4/90 (4.44%)
|
|
3/21 (14.29%)
|
|
1/18 (5.56%)
|
|
4/50 (8.00%)
|
|
2/51 (3.92%)
|
|
1/53 (1.89%)
|
|
5/44 (11.36%)
|
|
4/125 (3.20%)
|
|
3/62 (4.84%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
6/205 (2.93%)
|
|
5/132 (3.79%)
|
|
2/153 (1.31%)
|
|
Platelet count decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
3/15 (20.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
2/168 (1.19%)
|
|
2/60 (3.33%)
|
|
2/90 (2.22%)
|
|
3/21 (14.29%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
2/44 (4.55%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
4/205 (1.95%)
|
|
4/132 (3.03%)
|
|
1/153 (0.65%)
|
|
Neutrophil count decreased |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Activated partial thromboplastin time prolonged |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
4/156 (2.56%)
|
|
3/168 (1.79%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
2/21 (9.52%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
2/51 (3.92%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
2/205 (0.98%)
|
|
3/132 (2.27%)
|
|
1/153 (0.65%)
|
|
Blood bilirubin increased |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
3/168 (1.79%)
|
|
3/60 (5.00%)
|
|
4/90 (4.44%)
|
|
1/21 (4.76%)
|
|
1/18 (5.56%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
2/125 (1.60%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
3/205 (1.46%)
|
|
3/132 (2.27%)
|
|
1/153 (0.65%)
|
|
Blood glucose increased |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood pressure increased |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
CD4 lymphocytes decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Electrocardiogram QT prolonged |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
3/156 (1.92%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
5/50 (10.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
4/205 (1.95%)
|
|
1/132 (0.76%)
|
|
4/153 (2.61%)
|
|
Prothrombin time prolonged |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
C-reactive protein increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
2/103 (1.94%)
|
|
1/205 (0.49%)
|
|
3/132 (2.27%)
|
|
3/153 (1.96%)
|
|
Blood thyroid stimulating hormone increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
2/20 (10.00%)
|
|
2/103 (1.94%)
|
|
2/205 (0.98%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Breath sounds abnormal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
2/44 (4.55%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Haemoglobin decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Heart rate increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
International normalised ratio increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
2/168 (1.19%)
|
|
1/60 (1.67%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
2/62 (3.23%)
|
|
1/20 (5.00%)
|
|
2/103 (1.94%)
|
|
4/205 (1.95%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Rheumatoid factor increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Troponin I increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
White blood cell count increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Antinuclear antibody positive |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Bacterial test positive |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood follicle stimulating hormone increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood lactate dehydrogenase increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
2/51 (3.92%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
2/20 (10.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Blood magnesium decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
2/60 (3.33%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood phosphorus decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Blood uric acid increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cortisol increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Electrophoresis protein abnormal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Fibrin D dimer increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Haematocrit decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Heart rate irregular |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lymphocyte count |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lymphocyte count increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Mean cell volume decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pulmonary physical examination abnormal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Reticulocyte percentage increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Transaminases increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Troponin increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Urinary sediment present |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urine leukocyte esterase positive |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Human epidermal growth factor receptor decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Intestinal transit time abnormal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Neutrophil count increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nitrite urine present |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
White blood cells urine positive |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood creatine phosphokinase decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood potassium decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ejection fraction decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Electrocardiogram T wave abnormal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hepatic enzyme increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Liver function test increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Monocyte count increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Antineutrophil cytoplasmic antibody increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood iron decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vitamin D decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urine ketone body present |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood albumin decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Body temperature increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
3/153 (1.96%)
|
|
Corneal reflex decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ammonia increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Glycosylated haemoglobin increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urobilinogen urine increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Vitamin B12 decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Platelet count increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Antinuclear antibody increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Respiratory rate increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Skin turgor decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood cholesterol increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Streptobacillus test positive |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood sodium decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Carbohydrate antigen 125 increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Electrocardiogram ST segment abnormal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lymph node palpable |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Red blood cells urine positive |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Waist circumference increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood urea increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Glomerular filtration rate increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Reticulocyte count increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Thyroxine decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood creatine increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Glomerular filtration rate decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Occult blood positive |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Protein total decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Prothrombin level increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sputum abnormal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Thyroid hormones increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urine output decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood potassium increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cardiac murmur |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood magnesium increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood testosterone decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Klebsiella test positive |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Transferrin increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Transferrin saturation decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Amylase decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Blood calcium decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Blood chloride decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Blood lactic acid increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Computerised tomogram thorax abnormal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Eastern Cooperative Oncology Group performance status worsened |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Electrocardiogram QRS complex prolonged |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Electrocardiogram T wave peaked |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Electrocardiogram abnormal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Rheumatoid factor quantitative increased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Metabolism and nutrition disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Hyperglycaemia |
1/4 (25.00%)
|
|
2/13 (15.38%)
|
|
3/15 (20.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
11/184 (5.98%)
|
|
6/156 (3.85%)
|
|
4/168 (2.38%)
|
|
1/60 (1.67%)
|
|
4/90 (4.44%)
|
|
4/21 (19.05%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
2/51 (3.92%)
|
|
5/53 (9.43%)
|
|
4/44 (9.09%)
|
|
2/125 (1.60%)
|
|
4/62 (6.45%)
|
|
0/20 (0.00%)
|
|
4/103 (3.88%)
|
|
8/205 (3.90%)
|
|
4/132 (3.03%)
|
|
2/153 (1.31%)
|
|
Hypoalbuminaemia |
2/4 (50.00%)
|
|
2/13 (15.38%)
|
|
1/15 (6.67%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
8/184 (4.35%)
|
|
6/156 (3.85%)
|
|
6/168 (3.57%)
|
|
3/60 (5.00%)
|
|
3/90 (3.33%)
|
|
3/21 (14.29%)
|
|
0/18 (0.00%)
|
|
4/50 (8.00%)
|
|
0/51 (0.00%)
|
|
9/53 (16.98%)
|
|
2/44 (4.55%)
|
|
5/125 (4.00%)
|
|
2/62 (3.23%)
|
|
2/20 (10.00%)
|
|
5/103 (4.85%)
|
|
7/205 (3.41%)
|
|
9/132 (6.82%)
|
|
8/153 (5.23%)
|
|
Hypokalaemia |
1/4 (25.00%)
|
|
4/13 (30.77%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
17/184 (9.24%)
|
|
17/156 (10.90%)
|
|
9/168 (5.36%)
|
|
6/60 (10.00%)
|
|
3/90 (3.33%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
6/50 (12.00%)
|
|
6/51 (11.76%)
|
|
2/53 (3.77%)
|
|
4/44 (9.09%)
|
|
8/125 (6.40%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
11/103 (10.68%)
|
|
10/205 (4.88%)
|
|
15/132 (11.36%)
|
|
11/153 (7.19%)
|
|
Hyponatraemia |
2/4 (50.00%)
|
|
2/13 (15.38%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
16/184 (8.70%)
|
|
17/156 (10.90%)
|
|
3/168 (1.79%)
|
|
6/60 (10.00%)
|
|
4/90 (4.44%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
6/50 (12.00%)
|
|
2/51 (3.92%)
|
|
2/53 (3.77%)
|
|
6/44 (13.64%)
|
|
7/125 (5.60%)
|
|
4/62 (6.45%)
|
|
3/20 (15.00%)
|
|
12/103 (11.65%)
|
|
18/205 (8.78%)
|
|
12/132 (9.09%)
|
|
11/153 (7.19%)
|
|
Decreased appetite |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
2/15 (13.33%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
42/184 (22.83%)
|
|
36/156 (23.08%)
|
|
33/168 (19.64%)
|
|
17/60 (28.33%)
|
|
14/90 (15.56%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
13/50 (26.00%)
|
|
9/51 (17.65%)
|
|
12/53 (22.64%)
|
|
9/44 (20.45%)
|
|
21/125 (16.80%)
|
|
17/62 (27.42%)
|
|
3/20 (15.00%)
|
|
19/103 (18.45%)
|
|
53/205 (25.85%)
|
|
31/132 (23.48%)
|
|
18/153 (11.76%)
|
|
Hypomagnesaemia |
0/4 (0.00%)
|
|
2/13 (15.38%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
13/184 (7.07%)
|
|
5/156 (3.21%)
|
|
3/168 (1.79%)
|
|
3/60 (5.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
7/50 (14.00%)
|
|
1/51 (1.96%)
|
|
3/53 (5.66%)
|
|
2/44 (4.55%)
|
|
9/125 (7.20%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
13/103 (12.62%)
|
|
12/205 (5.85%)
|
|
9/132 (6.82%)
|
|
7/153 (4.58%)
|
|
Hyperkalaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
1/8 (12.50%)
|
|
5/184 (2.72%)
|
|
4/156 (2.56%)
|
|
1/168 (0.60%)
|
|
2/60 (3.33%)
|
|
1/90 (1.11%)
|
|
1/21 (4.76%)
|
|
1/18 (5.56%)
|
|
4/50 (8.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
2/44 (4.55%)
|
|
1/125 (0.80%)
|
|
4/62 (6.45%)
|
|
3/20 (15.00%)
|
|
0/103 (0.00%)
|
|
10/205 (4.88%)
|
|
4/132 (3.03%)
|
|
5/153 (3.27%)
|
|
Hypocalcaemia |
2/4 (50.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
3/60 (5.00%)
|
|
3/90 (3.33%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
5/50 (10.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
3/205 (1.46%)
|
|
6/132 (4.55%)
|
|
5/153 (3.27%)
|
|
Hypertriglyceridaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
4/156 (2.56%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
2/53 (3.77%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Hypochloraemia |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypophosphataemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
11/184 (5.98%)
|
|
6/156 (3.85%)
|
|
2/168 (1.19%)
|
|
3/60 (5.00%)
|
|
2/90 (2.22%)
|
|
2/21 (9.52%)
|
|
0/18 (0.00%)
|
|
8/50 (16.00%)
|
|
4/51 (7.84%)
|
|
1/53 (1.89%)
|
|
2/44 (4.55%)
|
|
2/125 (1.60%)
|
|
1/62 (1.61%)
|
|
2/20 (10.00%)
|
|
4/103 (3.88%)
|
|
12/205 (5.85%)
|
|
3/132 (2.27%)
|
|
9/153 (5.88%)
|
|
Dehydration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
18/184 (9.78%)
|
|
17/156 (10.90%)
|
|
6/168 (3.57%)
|
|
1/60 (1.67%)
|
|
6/90 (6.67%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
4/50 (8.00%)
|
|
6/51 (11.76%)
|
|
6/53 (11.32%)
|
|
4/44 (9.09%)
|
|
9/125 (7.20%)
|
|
5/62 (8.06%)
|
|
1/20 (5.00%)
|
|
10/103 (9.71%)
|
|
18/205 (8.78%)
|
|
14/132 (10.61%)
|
|
7/153 (4.58%)
|
|
Hypercalcaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
8/184 (4.35%)
|
|
3/156 (1.92%)
|
|
2/168 (1.19%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
2/21 (9.52%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
4/44 (9.09%)
|
|
1/125 (0.80%)
|
|
5/62 (8.06%)
|
|
3/20 (15.00%)
|
|
0/103 (0.00%)
|
|
6/205 (2.93%)
|
|
3/132 (2.27%)
|
|
11/153 (7.19%)
|
|
Hypovolaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Cachexia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Malnutrition |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
1/205 (0.49%)
|
|
2/132 (1.52%)
|
|
2/153 (1.31%)
|
|
Fluid overload |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Fluid retention |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hyperphosphataemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
2/51 (3.92%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Hyperuricaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
2/60 (3.33%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
2/125 (1.60%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
4/205 (1.95%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Iron deficiency |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
3/156 (1.92%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Steroid diabetes |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vitamin B12 deficiency |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypercholesterolaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
2/44 (4.55%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Abnormal loss of weight |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Appetite disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hyperamylasaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hyperlipidaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypoglycaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
3/153 (1.96%)
|
|
Hypophagia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Diabetes mellitus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypermagnesaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vitamin D deficiency |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypernatraemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
2/103 (1.94%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Acidosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hyperphagia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Type 2 diabetes mellitus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gout |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Iron overload |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Increased appetite |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Polydipsia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypoproteinaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Uraemic acidosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lactic acidosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Folate deficiency |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Metabolic acidosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
2/132 (1.52%)
|
|
0/153 (0.00%)
|
|
Vitamin B1 deficiency |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Musculoskeletal and connective tissue disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Back pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
3/15 (20.00%)
|
|
1/21 (4.76%)
|
|
3/8 (37.50%)
|
|
30/184 (16.30%)
|
|
29/156 (18.59%)
|
|
24/168 (14.29%)
|
|
7/60 (11.67%)
|
|
10/90 (11.11%)
|
|
2/21 (9.52%)
|
|
3/18 (16.67%)
|
|
10/50 (20.00%)
|
|
7/51 (13.73%)
|
|
11/53 (20.75%)
|
|
4/44 (9.09%)
|
|
15/125 (12.00%)
|
|
13/62 (20.97%)
|
|
2/20 (10.00%)
|
|
13/103 (12.62%)
|
|
33/205 (16.10%)
|
|
15/132 (11.36%)
|
|
14/153 (9.15%)
|
|
Myalgia |
1/4 (25.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
3/21 (14.29%)
|
|
1/8 (12.50%)
|
|
14/184 (7.61%)
|
|
10/156 (6.41%)
|
|
6/168 (3.57%)
|
|
2/60 (3.33%)
|
|
6/90 (6.67%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
4/50 (8.00%)
|
|
4/51 (7.84%)
|
|
6/53 (11.32%)
|
|
1/44 (2.27%)
|
|
9/125 (7.20%)
|
|
9/62 (14.52%)
|
|
3/20 (15.00%)
|
|
8/103 (7.77%)
|
|
9/205 (4.39%)
|
|
8/132 (6.06%)
|
|
10/153 (6.54%)
|
|
Pain in extremity |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
1/15 (6.67%)
|
|
2/21 (9.52%)
|
|
2/8 (25.00%)
|
|
11/184 (5.98%)
|
|
24/156 (15.38%)
|
|
14/168 (8.33%)
|
|
1/60 (1.67%)
|
|
5/90 (5.56%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
4/51 (7.84%)
|
|
5/53 (9.43%)
|
|
3/44 (6.82%)
|
|
4/125 (3.20%)
|
|
7/62 (11.29%)
|
|
1/20 (5.00%)
|
|
8/103 (7.77%)
|
|
13/205 (6.34%)
|
|
6/132 (4.55%)
|
|
7/153 (4.58%)
|
|
Arthralgia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
2/15 (13.33%)
|
|
1/21 (4.76%)
|
|
1/8 (12.50%)
|
|
24/184 (13.04%)
|
|
20/156 (12.82%)
|
|
26/168 (15.48%)
|
|
2/60 (3.33%)
|
|
8/90 (8.89%)
|
|
1/21 (4.76%)
|
|
5/18 (27.78%)
|
|
5/50 (10.00%)
|
|
8/51 (15.69%)
|
|
7/53 (13.21%)
|
|
6/44 (13.64%)
|
|
15/125 (12.00%)
|
|
12/62 (19.35%)
|
|
6/20 (30.00%)
|
|
12/103 (11.65%)
|
|
21/205 (10.24%)
|
|
10/132 (7.58%)
|
|
10/153 (6.54%)
|
|
Flank pain |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
2/21 (9.52%)
|
|
1/8 (12.50%)
|
|
6/184 (3.26%)
|
|
4/156 (2.56%)
|
|
4/168 (2.38%)
|
|
0/60 (0.00%)
|
|
3/90 (3.33%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
2/51 (3.92%)
|
|
2/53 (3.77%)
|
|
1/44 (2.27%)
|
|
2/125 (1.60%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
4/103 (3.88%)
|
|
9/205 (4.39%)
|
|
3/132 (2.27%)
|
|
0/153 (0.00%)
|
|
Muscle spasms |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
10/184 (5.43%)
|
|
3/156 (1.92%)
|
|
10/168 (5.95%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
3/51 (5.88%)
|
|
3/53 (5.66%)
|
|
2/44 (4.55%)
|
|
9/125 (7.20%)
|
|
5/62 (8.06%)
|
|
1/20 (5.00%)
|
|
7/103 (6.80%)
|
|
8/205 (3.90%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Muscular weakness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
7/184 (3.80%)
|
|
8/156 (5.13%)
|
|
4/168 (2.38%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
4/50 (8.00%)
|
|
2/51 (3.92%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
4/125 (3.20%)
|
|
4/62 (6.45%)
|
|
1/20 (5.00%)
|
|
3/103 (2.91%)
|
|
3/205 (1.46%)
|
|
2/132 (1.52%)
|
|
3/153 (1.96%)
|
|
Musculoskeletal chest pain |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
16/184 (8.70%)
|
|
9/156 (5.77%)
|
|
9/168 (5.36%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
1/21 (4.76%)
|
|
1/18 (5.56%)
|
|
5/50 (10.00%)
|
|
4/51 (7.84%)
|
|
8/53 (15.09%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
3/62 (4.84%)
|
|
3/20 (15.00%)
|
|
5/103 (4.85%)
|
|
6/205 (2.93%)
|
|
1/132 (0.76%)
|
|
6/153 (3.92%)
|
|
Musculoskeletal pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
2/15 (13.33%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
18/184 (9.78%)
|
|
16/156 (10.26%)
|
|
13/168 (7.74%)
|
|
2/60 (3.33%)
|
|
1/90 (1.11%)
|
|
2/21 (9.52%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
4/51 (7.84%)
|
|
9/53 (16.98%)
|
|
8/44 (18.18%)
|
|
6/125 (4.80%)
|
|
10/62 (16.13%)
|
|
4/20 (20.00%)
|
|
3/103 (2.91%)
|
|
15/205 (7.32%)
|
|
2/132 (1.52%)
|
|
8/153 (5.23%)
|
|
Neck pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
1/8 (12.50%)
|
|
9/184 (4.89%)
|
|
7/156 (4.49%)
|
|
10/168 (5.95%)
|
|
2/60 (3.33%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
1/44 (2.27%)
|
|
4/125 (3.20%)
|
|
3/62 (4.84%)
|
|
1/20 (5.00%)
|
|
4/103 (3.88%)
|
|
8/205 (3.90%)
|
|
1/132 (0.76%)
|
|
14/153 (9.15%)
|
|
Bone pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
5/184 (2.72%)
|
|
7/156 (4.49%)
|
|
5/168 (2.98%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
2/18 (11.11%)
|
|
2/50 (4.00%)
|
|
2/51 (3.92%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
2/205 (0.98%)
|
|
1/132 (0.76%)
|
|
3/153 (1.96%)
|
|
Groin pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
3/168 (1.79%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
8/205 (3.90%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Myositis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Trigger finger |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Arthritis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
3/125 (2.40%)
|
|
3/62 (4.84%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Joint swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Bursitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Muscle oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Muscle twitching |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pathological fracture |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Plantar fasciitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Spinal osteoarthritis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Spinal pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
2/50 (4.00%)
|
|
2/51 (3.92%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
1/153 (0.65%)
|
|
Tendonitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Musculoskeletal stiffness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
4/156 (2.56%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
3/153 (1.96%)
|
|
Pain in jaw |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
7/153 (4.58%)
|
|
Rotator cuff syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypercreatinaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Intervertebral disc protrusion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Joint range of motion decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Kyphosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Osteoarthritis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Osteoporosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
2/44 (4.55%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Periarthritis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Polymyalgia rheumatica |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Soft tissue swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Musculoskeletal discomfort |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Coccydynia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Joint lock |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Muscle atrophy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Rheumatoid arthritis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tendon disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tenosynovitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Joint stiffness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Finger deformity |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Soft tissue necrosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Autoimmune myositis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Clubbing |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Joint effusion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Limb discomfort |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Joint instability |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Limb mass |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bone cyst |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Crystal arthropathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Musculoskeletal disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Patellofemoral pain syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sjogren's syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Fracture pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Intervertebral disc degeneration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Muscle tightness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Polyarthritis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Myosclerosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Osteonecrosis of jaw |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Trismus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Bone fistula |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Mobility decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Torticollis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Neoplasms benign, malignant and unspecified (incl cysts and polyps) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Tumour pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
5/205 (2.44%)
|
|
1/132 (0.76%)
|
|
4/153 (2.61%)
|
|
Basal cell carcinoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Metastases to central nervous system |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Colon adenoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Eye naevus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gastrointestinal tract adenoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nasal cavity cancer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Skin cancer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Skin papilloma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Squamous cell carcinoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tumour flare |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Breast cancer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cancer pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
6/168 (3.57%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
2/51 (3.92%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
3/153 (1.96%)
|
|
Hair follicle tumour benign |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Haemangioma of bone |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Metastases to lymph nodes |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Metastases to skin |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tumour invasion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hepatic cancer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Malignant ascites |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Oesophageal squamous cell carcinoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Adrenocortical carcinoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Haemangioma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tumour haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
2/51 (3.92%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Malignant pleural effusion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Metastases to breast |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Metastases to liver |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Metastases to muscle |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Metastatic malignant melanoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tumour associated fever |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Tumour ulceration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Seborrhoeic keratosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
2/51 (3.92%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Squamous cell carcinoma of skin |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Acrochordon |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Melanocytic naevus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Myelodysplastic syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Neoplasm malignant |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Neoplasm swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Prostate cancer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Benign neoplasm of thyroid gland |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bladder transitional cell carcinoma stage 0 |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Metastases to bone |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Metastases to spine |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pancreatic neoplasm |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Transitional cell carcinoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urethral cancer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urinary tract carcinoma in situ |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tumour fistulisation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Basosquamous carcinoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Peritumoural oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Schwannoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Nervous system disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Headache |
0/4 (0.00%)
|
|
2/13 (15.38%)
|
|
1/15 (6.67%)
|
|
3/21 (14.29%)
|
|
1/8 (12.50%)
|
|
27/184 (14.67%)
|
|
27/156 (17.31%)
|
|
15/168 (8.93%)
|
|
2/60 (3.33%)
|
|
8/90 (8.89%)
|
|
1/21 (4.76%)
|
|
1/18 (5.56%)
|
|
6/50 (12.00%)
|
|
5/51 (9.80%)
|
|
4/53 (7.55%)
|
|
4/44 (9.09%)
|
|
16/125 (12.80%)
|
|
9/62 (14.52%)
|
|
4/20 (20.00%)
|
|
6/103 (5.83%)
|
|
16/205 (7.80%)
|
|
8/132 (6.06%)
|
|
17/153 (11.11%)
|
|
Dizziness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
1/8 (12.50%)
|
|
22/184 (11.96%)
|
|
17/156 (10.90%)
|
|
11/168 (6.55%)
|
|
5/60 (8.33%)
|
|
7/90 (7.78%)
|
|
2/21 (9.52%)
|
|
1/18 (5.56%)
|
|
4/50 (8.00%)
|
|
4/51 (7.84%)
|
|
5/53 (9.43%)
|
|
4/44 (9.09%)
|
|
9/125 (7.20%)
|
|
5/62 (8.06%)
|
|
3/20 (15.00%)
|
|
12/103 (11.65%)
|
|
12/205 (5.85%)
|
|
5/132 (3.79%)
|
|
13/153 (8.50%)
|
|
Lethargy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
0/156 (0.00%)
|
|
5/168 (2.98%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Paraesthesia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
2/156 (1.28%)
|
|
3/168 (1.79%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
3/62 (4.84%)
|
|
1/20 (5.00%)
|
|
2/103 (1.94%)
|
|
3/205 (1.46%)
|
|
1/132 (0.76%)
|
|
4/153 (2.61%)
|
|
Dysgeusia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
5/156 (3.21%)
|
|
4/168 (2.38%)
|
|
3/60 (5.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
5/51 (9.80%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
2/125 (1.60%)
|
|
4/62 (6.45%)
|
|
1/20 (5.00%)
|
|
2/103 (1.94%)
|
|
4/205 (1.95%)
|
|
1/132 (0.76%)
|
|
2/153 (1.31%)
|
|
Hypoaesthesia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
1/156 (0.64%)
|
|
3/168 (1.79%)
|
|
2/60 (3.33%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
2/51 (3.92%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
3/125 (2.40%)
|
|
2/62 (3.23%)
|
|
1/20 (5.00%)
|
|
4/103 (3.88%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
3/153 (1.96%)
|
|
Neuralgia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
3/205 (1.46%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Somnolence |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
3/156 (1.92%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
3/51 (5.88%)
|
|
1/53 (1.89%)
|
|
3/44 (6.82%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Dysarthria |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
2/51 (3.92%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Memory impairment |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
3/156 (1.92%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Peripheral sensory neuropathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
4/156 (2.56%)
|
|
2/168 (1.19%)
|
|
1/60 (1.67%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
1/50 (2.00%)
|
|
2/51 (3.92%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
4/125 (3.20%)
|
|
0/62 (0.00%)
|
|
3/20 (15.00%)
|
|
3/103 (2.91%)
|
|
5/205 (2.44%)
|
|
4/132 (3.03%)
|
|
2/153 (1.31%)
|
|
Restless legs syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
1/156 (0.64%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
3/125 (2.40%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Syncope |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
2/132 (1.52%)
|
|
2/153 (1.31%)
|
|
Vasogenic cerebral oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Balance disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Migraine |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Monoparesis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Radiculopathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tremor |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
4/156 (2.56%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
1/44 (2.27%)
|
|
4/125 (3.20%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Aphasia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Carotid artery stenosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Depressed level of consciousness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Disturbance in attention |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Dizziness postural |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Facial paresis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hemiparesis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Horner's syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Neuropathy peripheral |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
3/156 (1.92%)
|
|
2/168 (1.19%)
|
|
2/60 (3.33%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
2/44 (4.55%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
3/153 (1.96%)
|
|
Parosmia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Peripheral sensorimotor neuropathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Phantom limb syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Seizure |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Spinal cord compression |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sciatica |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
3/156 (1.92%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
6/205 (2.93%)
|
|
1/132 (0.76%)
|
|
3/153 (1.96%)
|
|
Ataxia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Burning sensation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Cerebral infarction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cerebrovascular accident |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cognitive disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hepatic encephalopathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Hypersomnia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypoxic-ischaemic encephalopathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Intracranial aneurysm |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Monoplegia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nerve compression |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Parkinson's disease |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Presyncope |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Psychomotor skills impaired |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sinus headache |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Subarachnoid haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Taste disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hyperaesthesia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
4/168 (2.38%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Myoclonus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Psychomotor hyperactivity |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tongue paralysis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ageusia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Peripheral motor neuropathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
2/132 (1.52%)
|
|
1/153 (0.65%)
|
|
Dyskinesia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hemianopia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Akathisia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Asterixis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Dysaesthesia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Encephalopathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Facial paralysis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Motor dysfunction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Muscle spasticity |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Polyneuropathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Carpal tunnel syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
2/51 (3.92%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Speech disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Febrile convulsion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Narcolepsy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sensory disturbance |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Altered state of consciousness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Amnesia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
4/205 (1.95%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Apraxia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Coma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Coordination abnormal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Resting tremor |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sensory loss |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypotonia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Aphonia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Brain oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Carotid sinus syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Metabolic encephalopathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Pachymeningitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Unresponsive to stimuli |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Product Issues |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Device occlusion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Device leakage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Device malfunction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Thrombosis in device |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Device breakage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Device dislocation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Device material opacification |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Psychiatric disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Insomnia |
1/4 (25.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
14/184 (7.61%)
|
|
13/156 (8.33%)
|
|
13/168 (7.74%)
|
|
5/60 (8.33%)
|
|
8/90 (8.89%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
4/50 (8.00%)
|
|
5/51 (9.80%)
|
|
6/53 (11.32%)
|
|
2/44 (4.55%)
|
|
12/125 (9.60%)
|
|
3/62 (4.84%)
|
|
3/20 (15.00%)
|
|
6/103 (5.83%)
|
|
17/205 (8.29%)
|
|
13/132 (9.85%)
|
|
5/153 (3.27%)
|
|
Anxiety |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
27/184 (14.67%)
|
|
11/156 (7.05%)
|
|
11/168 (6.55%)
|
|
5/60 (8.33%)
|
|
4/90 (4.44%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
2/50 (4.00%)
|
|
2/51 (3.92%)
|
|
3/53 (5.66%)
|
|
5/44 (11.36%)
|
|
6/125 (4.80%)
|
|
2/62 (3.23%)
|
|
1/20 (5.00%)
|
|
8/103 (7.77%)
|
|
17/205 (8.29%)
|
|
3/132 (2.27%)
|
|
7/153 (4.58%)
|
|
Hallucination |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Restlessness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Confusional state |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
8/184 (4.35%)
|
|
5/156 (3.21%)
|
|
3/168 (1.79%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
2/103 (1.94%)
|
|
11/205 (5.37%)
|
|
1/132 (0.76%)
|
|
6/153 (3.92%)
|
|
Depression |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
8/156 (5.13%)
|
|
1/168 (0.60%)
|
|
2/60 (3.33%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
1/51 (1.96%)
|
|
2/53 (3.77%)
|
|
2/44 (4.55%)
|
|
2/125 (1.60%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
8/205 (3.90%)
|
|
2/132 (1.52%)
|
|
5/153 (3.27%)
|
|
Depressive symptom |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
3/90 (3.33%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Agitation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
4/205 (1.95%)
|
|
1/132 (0.76%)
|
|
2/153 (1.31%)
|
|
Irritability |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Major depression |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Delirium |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Depressed mood |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Mood altered |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sleep disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Mental status changes |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Anxiety disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Apathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bipolar disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Stress |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Libido decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Emotional distress |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nightmare |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Adjustment disorder with mixed anxiety and depressed mood |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Hallucination, visual |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Panic attack |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Substance-induced psychotic disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Affective disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Personality change |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Mood swings |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Mental disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Disorientation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Panic disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Affect lability |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Renal and urinary disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Proteinuria |
0/4 (0.00%)
|
|
2/13 (15.38%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
4/156 (2.56%)
|
|
3/168 (1.79%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
2/21 (9.52%)
|
|
0/18 (0.00%)
|
|
5/50 (10.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
3/125 (2.40%)
|
|
3/62 (4.84%)
|
|
1/20 (5.00%)
|
|
2/103 (1.94%)
|
|
4/205 (1.95%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Dysuria |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
6/184 (3.26%)
|
|
5/156 (3.21%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
3/90 (3.33%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
2/51 (3.92%)
|
|
0/53 (0.00%)
|
|
2/44 (4.55%)
|
|
5/125 (4.00%)
|
|
4/62 (6.45%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
11/205 (5.37%)
|
|
2/132 (1.52%)
|
|
1/153 (0.65%)
|
|
Haemoglobinuria |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pollakiuria |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
3/184 (1.63%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
1/51 (1.96%)
|
|
2/53 (3.77%)
|
|
2/44 (4.55%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
7/205 (3.41%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Haematuria |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
10/156 (6.41%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
3/51 (5.88%)
|
|
3/53 (5.66%)
|
|
2/44 (4.55%)
|
|
1/125 (0.80%)
|
|
3/62 (4.84%)
|
|
2/20 (10.00%)
|
|
1/103 (0.97%)
|
|
17/205 (8.29%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Acute kidney injury |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
5/156 (3.21%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
2/44 (4.55%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
10/205 (4.88%)
|
|
4/132 (3.03%)
|
|
0/153 (0.00%)
|
|
Nocturia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Urinary retention |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
3/156 (1.92%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
5/205 (2.44%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Azotaemia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Chromaturia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Costovertebral angle tenderness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hydronephrosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
6/103 (5.83%)
|
|
6/205 (2.93%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Nephrolithiasis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Renal infarct |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urinary tract pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urine odour abnormal |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urinary incontinence |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
3/156 (1.92%)
|
|
3/168 (1.79%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
6/205 (2.93%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Micturition urgency |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
3/156 (1.92%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Bladder spasm |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
5/205 (2.44%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Calculus urinary |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Chronic kidney disease |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
3/132 (2.27%)
|
|
1/153 (0.65%)
|
|
Leukocyturia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urethral disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urine flow decreased |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Incontinence |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Stress urinary incontinence |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypertonic bladder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Renal failure |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
2/44 (4.55%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
6/205 (2.93%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urinary tract obstruction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
1/21 (4.76%)
|
|
1/18 (5.56%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
4/205 (1.95%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Renal colic |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Polyuria |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Renal pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bladder dilatation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bladder trabeculation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nephritis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cystitis noninfective |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Urinary hesitation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bladder pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ureteric obstruction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urethral stenosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urge incontinence |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Urine abnormality |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vaginal haematoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ejaculation disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Reproductive system and breast disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Adnexa uteri mass |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Breast tenderness |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pelvic discomfort |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Postmenopausal haemorrhage |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vaginal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
4/205 (1.95%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pelvic pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
1/18 (5.56%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
3/44 (6.82%)
|
|
1/125 (0.80%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
5/205 (2.44%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Benign prostatic hyperplasia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Breast mass |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Breast haematoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Breast swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Erectile dysfunction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Genital rash |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nipple pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Scrotal oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Scrotal swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Testicular oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vaginal discharge |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Vulvovaginal pruritus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
3/62 (4.84%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Genital discomfort |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Prostatomegaly |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vulvovaginal dryness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vulvovaginal pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Gynaecomastia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Metrorrhagia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Breast pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Dyspareunia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Haematospermia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Prostatitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Varicocele |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oedema genital |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Penile swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Testicular pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Uterine atrophy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sexual dysfunction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Scrotal pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Menopausal symptoms |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Respiratory, thoracic and mediastinal disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Cough |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
3/15 (20.00%)
|
|
3/21 (14.29%)
|
|
1/8 (12.50%)
|
|
51/184 (27.72%)
|
|
26/156 (16.67%)
|
|
23/168 (13.69%)
|
|
5/60 (8.33%)
|
|
11/90 (12.22%)
|
|
1/21 (4.76%)
|
|
3/18 (16.67%)
|
|
15/50 (30.00%)
|
|
11/51 (21.57%)
|
|
20/53 (37.74%)
|
|
5/44 (11.36%)
|
|
9/125 (7.20%)
|
|
22/62 (35.48%)
|
|
3/20 (15.00%)
|
|
9/103 (8.74%)
|
|
37/205 (18.05%)
|
|
14/132 (10.61%)
|
|
13/153 (8.50%)
|
|
Rhinitis allergic |
0/4 (0.00%)
|
|
2/13 (15.38%)
|
|
1/15 (6.67%)
|
|
2/21 (9.52%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
5/156 (3.21%)
|
|
3/168 (1.79%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
3/125 (2.40%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Dyspnoea |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
1/15 (6.67%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
26/184 (14.13%)
|
|
33/156 (21.15%)
|
|
19/168 (11.31%)
|
|
6/60 (10.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
12/50 (24.00%)
|
|
7/51 (13.73%)
|
|
14/53 (26.42%)
|
|
9/44 (20.45%)
|
|
13/125 (10.40%)
|
|
14/62 (22.58%)
|
|
8/20 (40.00%)
|
|
21/103 (20.39%)
|
|
33/205 (16.10%)
|
|
10/132 (7.58%)
|
|
16/153 (10.46%)
|
|
Dyspnoea exertional |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
2/21 (9.52%)
|
|
0/8 (0.00%)
|
|
25/184 (13.59%)
|
|
12/156 (7.69%)
|
|
24/168 (14.29%)
|
|
1/60 (1.67%)
|
|
4/90 (4.44%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
8/50 (16.00%)
|
|
4/51 (7.84%)
|
|
5/53 (9.43%)
|
|
3/44 (6.82%)
|
|
8/125 (6.40%)
|
|
3/62 (4.84%)
|
|
2/20 (10.00%)
|
|
0/103 (0.00%)
|
|
7/205 (3.41%)
|
|
3/132 (2.27%)
|
|
2/153 (1.31%)
|
|
Productive cough |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
2/21 (9.52%)
|
|
0/8 (0.00%)
|
|
13/184 (7.07%)
|
|
11/156 (7.05%)
|
|
4/168 (2.38%)
|
|
1/60 (1.67%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
4/50 (8.00%)
|
|
0/51 (0.00%)
|
|
5/53 (9.43%)
|
|
3/44 (6.82%)
|
|
2/125 (1.60%)
|
|
5/62 (8.06%)
|
|
3/20 (15.00%)
|
|
2/103 (1.94%)
|
|
9/205 (4.39%)
|
|
1/132 (0.76%)
|
|
13/153 (8.50%)
|
|
Wheezing |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
2/21 (9.52%)
|
|
0/8 (0.00%)
|
|
8/184 (4.35%)
|
|
4/156 (2.56%)
|
|
6/168 (3.57%)
|
|
2/60 (3.33%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
4/20 (20.00%)
|
|
3/103 (2.91%)
|
|
3/205 (1.46%)
|
|
2/132 (1.52%)
|
|
2/153 (1.31%)
|
|
Pleural effusion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
7/184 (3.80%)
|
|
4/156 (2.56%)
|
|
10/168 (5.95%)
|
|
2/60 (3.33%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
3/51 (5.88%)
|
|
5/53 (9.43%)
|
|
1/44 (2.27%)
|
|
5/125 (4.00%)
|
|
1/62 (1.61%)
|
|
2/20 (10.00%)
|
|
5/103 (4.85%)
|
|
8/205 (3.90%)
|
|
8/132 (6.06%)
|
|
3/153 (1.96%)
|
|
Upper-airway cough syndrome |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
7/184 (3.80%)
|
|
2/156 (1.28%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
3/205 (1.46%)
|
|
2/132 (1.52%)
|
|
4/153 (2.61%)
|
|
Atelectasis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Dysphonia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
6/184 (3.26%)
|
|
5/156 (3.21%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
4/62 (6.45%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
2/205 (0.98%)
|
|
1/132 (0.76%)
|
|
5/153 (3.27%)
|
|
Epistaxis |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
3/125 (2.40%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
5/153 (3.27%)
|
|
Nasal congestion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
12/184 (6.52%)
|
|
7/156 (4.49%)
|
|
5/168 (2.98%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
2/50 (4.00%)
|
|
1/51 (1.96%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
4/125 (3.20%)
|
|
2/62 (3.23%)
|
|
1/20 (5.00%)
|
|
4/103 (3.88%)
|
|
2/205 (0.98%)
|
|
2/132 (1.52%)
|
|
3/153 (1.96%)
|
|
Oropharyngeal pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
9/184 (4.89%)
|
|
8/156 (5.13%)
|
|
7/168 (4.17%)
|
|
2/60 (3.33%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
2/44 (4.55%)
|
|
4/125 (3.20%)
|
|
3/62 (4.84%)
|
|
1/20 (5.00%)
|
|
9/103 (8.74%)
|
|
7/205 (3.41%)
|
|
2/132 (1.52%)
|
|
5/153 (3.27%)
|
|
Pleuritic pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
4/156 (2.56%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Pulmonary embolism |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
5/156 (3.21%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
2/44 (4.55%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
6/205 (2.93%)
|
|
3/132 (2.27%)
|
|
0/153 (0.00%)
|
|
Respiratory symptom |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hiccups |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
3/132 (2.27%)
|
|
0/153 (0.00%)
|
|
Haemoptysis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
16/184 (8.70%)
|
|
10/156 (6.41%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
3/53 (5.66%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
5/205 (2.44%)
|
|
2/132 (1.52%)
|
|
11/153 (7.19%)
|
|
Chronic obstructive pulmonary disease |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
8/184 (4.35%)
|
|
4/156 (2.56%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Hypoxia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
6/184 (3.26%)
|
|
4/156 (2.56%)
|
|
3/168 (1.79%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
4/205 (1.95%)
|
|
1/132 (0.76%)
|
|
6/153 (3.92%)
|
|
Pneumonitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
5/156 (3.21%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
2/51 (3.92%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
2/62 (3.23%)
|
|
3/20 (15.00%)
|
|
0/103 (0.00%)
|
|
6/205 (2.93%)
|
|
2/132 (1.52%)
|
|
4/153 (2.61%)
|
|
Rhinorrhoea |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
5/156 (3.21%)
|
|
4/168 (2.38%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
6/205 (2.93%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Pneumothorax |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
3/156 (1.92%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
2/153 (1.31%)
|
|
Respiratory tract congestion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Allergic sinusitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Emphysema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lung infiltration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Nasal dryness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Orthopnoea |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pulmonary congestion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Pulmonary fibrosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pulmonary venous thrombosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Respiratory distress |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Sinus congestion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
3/125 (2.40%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Tachypnoea |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Throat irritation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Throat tightness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Hypercapnia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pulmonary haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bronchial obstruction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Bronchitis chronic |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lower respiratory tract congestion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Paranasal sinus hypersecretion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pulmonary oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Rhonchi |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Tracheal pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hydrothorax |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Paranasal sinus discomfort |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pleurisy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Rales |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sputum discoloured |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Stridor |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pneumonia aspiration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Aspiration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
3/153 (1.96%)
|
|
Asthma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Laryngeal haemorrhage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Respiratory tract inflammation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Bronchopneumopathy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Bronchospasm |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypopnoea |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lung disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
2/44 (4.55%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oropharyngeal plaque |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Sneezing |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pulmonary hypertension |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Dyspnoea at rest |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pharyngeal swelling |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pulmonary pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Acute respiratory distress syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nasal inflammation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Allergic pharyngitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Oropharyngeal discomfort |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Painful respiration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Respiratory acidosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Respiratory failure |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Rhinalgia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Acute respiratory failure |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Laryngeal inflammation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Obstructive airways disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Pulmonary mass |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Upper respiratory tract congestion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Upper respiratory tract irritation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Chylothorax |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Hyperventilation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Choking |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Increased viscosity of bronchial secretion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Laryngeal obstruction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Laryngeal pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Pharyngeal erythema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Pharyngeal oedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Skin and subcutaneous tissue disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Rash |
1/4 (25.00%)
|
|
1/13 (7.69%)
|
|
2/15 (13.33%)
|
|
2/21 (9.52%)
|
|
2/8 (25.00%)
|
|
12/184 (6.52%)
|
|
17/156 (10.90%)
|
|
7/168 (4.17%)
|
|
2/60 (3.33%)
|
|
11/90 (12.22%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
10/50 (20.00%)
|
|
4/51 (7.84%)
|
|
5/53 (9.43%)
|
|
4/44 (9.09%)
|
|
13/125 (10.40%)
|
|
11/62 (17.74%)
|
|
1/20 (5.00%)
|
|
6/103 (5.83%)
|
|
23/205 (11.22%)
|
|
6/132 (4.55%)
|
|
12/153 (7.84%)
|
|
Pruritus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
2/8 (25.00%)
|
|
10/184 (5.43%)
|
|
14/156 (8.97%)
|
|
9/168 (5.36%)
|
|
1/60 (1.67%)
|
|
14/90 (15.56%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
7/50 (14.00%)
|
|
6/51 (11.76%)
|
|
7/53 (13.21%)
|
|
6/44 (13.64%)
|
|
9/125 (7.20%)
|
|
15/62 (24.19%)
|
|
0/20 (0.00%)
|
|
6/103 (5.83%)
|
|
27/205 (13.17%)
|
|
8/132 (6.06%)
|
|
18/153 (11.76%)
|
|
Urticaria |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
4/205 (1.95%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Dermatitis acneiform |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
1/44 (2.27%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Rash maculo-papular |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
1/21 (4.76%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
5/156 (3.21%)
|
|
5/168 (2.98%)
|
|
3/60 (5.00%)
|
|
3/90 (3.33%)
|
|
2/21 (9.52%)
|
|
2/18 (11.11%)
|
|
4/50 (8.00%)
|
|
2/51 (3.92%)
|
|
1/53 (1.89%)
|
|
5/44 (11.36%)
|
|
9/125 (7.20%)
|
|
2/62 (3.23%)
|
|
2/20 (10.00%)
|
|
1/103 (0.97%)
|
|
8/205 (3.90%)
|
|
2/132 (1.52%)
|
|
2/153 (1.31%)
|
|
Rash pruritic |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
5/184 (2.72%)
|
|
2/156 (1.28%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
2/51 (3.92%)
|
|
0/53 (0.00%)
|
|
2/44 (4.55%)
|
|
2/125 (1.60%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
4/205 (1.95%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Rash vesicular |
1/4 (25.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Skin hyperpigmentation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
1/8 (12.50%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Night sweats |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
11/184 (5.98%)
|
|
5/156 (3.21%)
|
|
1/168 (0.60%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
2/51 (3.92%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
7/205 (3.41%)
|
|
4/132 (3.03%)
|
|
6/153 (3.92%)
|
|
Erythema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
8/184 (4.35%)
|
|
1/156 (0.64%)
|
|
6/168 (3.57%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
3/51 (5.88%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
4/62 (6.45%)
|
|
0/20 (0.00%)
|
|
4/103 (3.88%)
|
|
4/205 (1.95%)
|
|
0/132 (0.00%)
|
|
6/153 (3.92%)
|
|
Dry skin |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
14/156 (8.97%)
|
|
8/168 (4.76%)
|
|
0/60 (0.00%)
|
|
4/90 (4.44%)
|
|
0/21 (0.00%)
|
|
1/18 (5.56%)
|
|
4/50 (8.00%)
|
|
2/51 (3.92%)
|
|
3/53 (5.66%)
|
|
3/44 (6.82%)
|
|
3/125 (2.40%)
|
|
9/62 (14.52%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
14/205 (6.83%)
|
|
3/132 (2.27%)
|
|
8/153 (5.23%)
|
|
Hyperhidrosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
5/184 (2.72%)
|
|
4/156 (2.56%)
|
|
4/168 (2.38%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
4/53 (7.55%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
5/103 (4.85%)
|
|
3/205 (1.46%)
|
|
2/132 (1.52%)
|
|
1/153 (0.65%)
|
|
Dermatitis contact |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
2/50 (4.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Skin lesion |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
3/153 (1.96%)
|
|
Dermatitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Pain of skin |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Psoriasis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Rash generalised |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
0/156 (0.00%)
|
|
3/168 (1.79%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Acne |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Actinic keratosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
1/20 (5.00%)
|
|
1/103 (0.97%)
|
|
3/205 (1.46%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Alopecia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
6/156 (3.85%)
|
|
3/168 (1.79%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
2/44 (4.55%)
|
|
4/125 (3.20%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
4/205 (1.95%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Anhidrosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Decubitus ulcer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Dermatitis exfoliative generalised |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Eczema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
3/156 (1.92%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
2/53 (3.77%)
|
|
0/44 (0.00%)
|
|
3/125 (2.40%)
|
|
3/62 (4.84%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
2/132 (1.52%)
|
|
2/153 (1.31%)
|
|
Haemorrhage subcutaneous |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ingrowing nail |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Onycholysis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Paraneoplastic rash |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pigmentation disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pruritus generalised |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
4/156 (2.56%)
|
|
4/168 (2.38%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Skin exfoliation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Skin irritation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Skin mass |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Skin ulcer |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
3/156 (1.92%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Hyperkeratosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
3/156 (1.92%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Rash macular |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Photosensitivity reaction |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Purpura |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
2/156 (1.28%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Blister |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Hand dermatitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lichen planus |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nail discolouration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Papule |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Petechiae |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Rash papular |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Skin discolouration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Angioedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ecchymosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Facial wasting |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nail disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pemphigoid |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Skin hypopigmentation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Rash erythematous |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
2/90 (2.22%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Rosacea |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
2/60 (3.33%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Cold sweat |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Dermatitis bullous |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypertrichosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Palmar-plantar erythrodysaesthesia syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Seborrhoeic dermatitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Dermatosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Skin burning sensation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vitiligo |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Macule |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nail toxicity |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Erythema ab igne |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lichenoid keratosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Melanocytic hyperplasia |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Scar pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Diabetic foot |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nail dystrophy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nail pigmentation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Nail ridging |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
1/20 (5.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Skin induration |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Skin toxicity |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Idiopathic guttate hypomelanosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Onychomadesis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Erythema multiforme |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Granuloma skin |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Skin fissures |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Xeroderma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Blood blister |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Drug eruption |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Skin disorder |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Skin hypertrophy |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Swelling face |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Solar lentigo |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Actinic cheilitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Dermatitis allergic |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Madarosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Nodular rash |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Onychoclasis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Social circumstances |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Loss of personal independence in daily activities |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pregnancy of partner |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Surgical and medical procedures |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Dental implantation |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Manual lymphatic drainage |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Therapeutic procedure |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Infection prophylaxis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vascular disorders |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Hypertension |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
3/15 (20.00%)
|
|
3/21 (14.29%)
|
|
1/8 (12.50%)
|
|
8/184 (4.35%)
|
|
26/156 (16.67%)
|
|
12/168 (7.14%)
|
|
2/60 (3.33%)
|
|
5/90 (5.56%)
|
|
1/21 (4.76%)
|
|
0/18 (0.00%)
|
|
12/50 (24.00%)
|
|
5/51 (9.80%)
|
|
6/53 (11.32%)
|
|
4/44 (9.09%)
|
|
13/125 (10.40%)
|
|
6/62 (9.68%)
|
|
4/20 (20.00%)
|
|
11/103 (10.68%)
|
|
30/205 (14.63%)
|
|
9/132 (6.82%)
|
|
19/153 (12.42%)
|
|
Hypotension |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
3/21 (14.29%)
|
|
0/8 (0.00%)
|
|
9/184 (4.89%)
|
|
6/156 (3.85%)
|
|
3/168 (1.79%)
|
|
2/60 (3.33%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
3/50 (6.00%)
|
|
1/51 (1.96%)
|
|
4/53 (7.55%)
|
|
5/44 (11.36%)
|
|
4/125 (3.20%)
|
|
3/62 (4.84%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
6/205 (2.93%)
|
|
5/132 (3.79%)
|
|
4/153 (2.61%)
|
|
Embolism |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Flushing |
0/4 (0.00%)
|
|
1/13 (7.69%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
3/184 (1.63%)
|
|
3/156 (1.92%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vena cava thrombosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
1/15 (6.67%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Hot flush |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
8/184 (4.35%)
|
|
7/156 (4.49%)
|
|
5/168 (2.98%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
6/125 (4.80%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
4/205 (1.95%)
|
|
3/132 (2.27%)
|
|
2/153 (1.31%)
|
|
Deep vein thrombosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
4/184 (2.17%)
|
|
4/156 (2.56%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
1/90 (1.11%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
2/62 (3.23%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
2/205 (0.98%)
|
|
2/132 (1.52%)
|
|
1/153 (0.65%)
|
|
Haematoma |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
2/184 (1.09%)
|
|
2/156 (1.28%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Arterial thrombosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Ischaemic limb pain |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Jugular vein thrombosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
1/156 (0.64%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Orthostatic hypotension |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
2/103 (1.94%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
2/153 (1.31%)
|
|
Venous thrombosis limb |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
1/156 (0.64%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Lymphoedema |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
2/168 (1.19%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
2/125 (1.60%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
3/103 (2.91%)
|
|
2/205 (0.98%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Peripheral embolism |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
1/168 (0.60%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Brachiocephalic vein thrombosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
1/60 (1.67%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Subclavian vein thrombosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
1/153 (0.65%)
|
|
Thrombosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
1/184 (0.54%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
1/125 (0.80%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Aortitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
1/50 (2.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypovolaemic shock |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Peripheral coldness |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
1/51 (1.96%)
|
|
1/53 (1.89%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pallor |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Phlebitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
1/44 (2.27%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Thrombophlebitis superficial |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
1/62 (1.61%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Pelvic venous thrombosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Phlebitis superficial |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Raynaud's phenomenon |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
1/103 (0.97%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Arteriosclerosis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Hypertensive urgency |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
1/205 (0.49%)
|
|
0/132 (0.00%)
|
|
0/153 (0.00%)
|
|
Vasculitis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
1/132 (0.76%)
|
|
0/153 (0.00%)
|
|
Hypertensive crisis |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Superior vena cava syndrome |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Varicose vein |
0/4 (0.00%)
|
|
0/13 (0.00%)
|
|
0/15 (0.00%)
|
|
0/21 (0.00%)
|
|
0/8 (0.00%)
|
|
0/184 (0.00%)
|
|
0/156 (0.00%)
|
|
0/168 (0.00%)
|
|
0/60 (0.00%)
|
|
0/90 (0.00%)
|
|
0/21 (0.00%)
|
|
0/18 (0.00%)
|
|
0/50 (0.00%)
|
|
0/51 (0.00%)
|
|
0/53 (0.00%)
|
|
0/44 (0.00%)
|
|
0/125 (0.00%)
|
|
0/62 (0.00%)
|
|
0/20 (0.00%)
|
|
0/103 (0.00%)
|
|
0/205 (0.00%)
|
|
0/132 (0.00%)
|
|
1/153 (0.65%)
|
|
Term from vocabulary, MedDRA Version 18.1
Indicates events were collected by non-systematic assessment
|