Antibiotics In Modic Changes (AIM)

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ClinicalTrials.gov Identifier: NCT02323412

Recruitment Status : Completed

First Posted : December 23, 2014

Last Update Posted : September 27, 2021

View this study on the modernized ClinicalTrials.gov

Sponsor:

Collaborators:

Haukeland University Hospital

St. Olavs Hospital

University Hospital of North Norway

Drammen sykehus

Sykehuset Ostfold

Information provided by (Responsible Party):

Kjersti Storheim, Oslo University Hospital

No Study Results Posted on ClinicalTrials.gov for this Study

About Study Results Reporting on ClinicalTrials.gov

Recruitment Status :	Completed
Actual Primary Completion Date :	September 21, 2018
Actual Study Completion Date :	November 6, 2018

Publications of Results:

Braten LCH, Rolfsen MP, Espeland A, Wigemyr M, Assmus J, Froholdt A, Haugen AJ, Marchand GH, Kristoffersen PM, Lutro O, Randen S, Wilhelmsen M, Winsvold BS, Kadar TI, Holmgard TE, Vigeland MD, Vetti N, Nygaard OP, Lie BA, Hellum C, Anke A, Grotle M, Schistad EI, Skouen JS, Grovle L, Brox JI, Zwart JA, Storheim K; AIM study group. Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial. BMJ. 2019 Oct 16;367:l5654. doi: 10.1136/bmj.l5654. Erratum In: BMJ. 2020 Feb 11;368:m546.

Other Publications:

Storheim K, Espeland A, Grovle L, Skouen JS, Assmus J, Anke A, Froholdt A, Pedersen LM, Haugen AJ, Fors T, Schistad E, Lutro O, Marchand GH, Kadar T, Vetti N, Randen S, Nygaard OP, Brox JI, Grotle M, Zwart JA. Antibiotic treatment In patients with chronic low back pain and Modic changes (the AIM study): study protocol for a randomised controlled trial. Trials. 2017 Dec 15;18(1):596. doi: 10.1186/s13063-017-2306-8.

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Braten LCH, Grovle L, Espeland A, Pripp AH, Grotle M, Helllum C, Haugen AJ, Froholdt A, Rolfsen MP, Nygaard OP, Lutro O, Kristoffersen PM, Anke A, Schistad EI, Skouen JS, Brox JI, Zwart JA, Storheim K; AIM-study group. Clinical effect modifiers of antibiotic treatment in patients with chronic low back pain and Modic changes - secondary analyses of a randomised, placebo-controlled trial (the AIM study). BMC Musculoskelet Disord. 2020 Jul 13;21(1):458. doi: 10.1186/s12891-020-03422-y.

Grotle M, Braten LC, Brox JI, Espeland A, Zolic-Karlsson Z, Munk Killingmo R, Tingulstad A, Grovle L, Froholdt A, Kristoffersen PM, Wigemyr M, van Tulder MW, Storheim K, Zwart JA; AIM-study group. Cost-utility analysis of antibiotic treatment in patients with chronic low back pain and Modic changes: results from a randomised, placebo-controlled trial in Norway (the AIM study). BMJ Open. 2020 Jun 15;10(6):e035461. doi: 10.1136/bmjopen-2019-035461.

Braten LCH, Schistad EI, Espeland A, Kristoffersen PM, Haugen AJ, Marchand GH, Vetti N, Pripp AH, Kadar TI, Skouen JS, Grotle M, Grovle L, Zwart JA, Brox JI, Storheim K; AIM-study group. Association of Modic change types and their short tau inversion recovery signals with clinical characteristics- a cross sectional study of chronic low back pain patients in the AIM-study. BMC Musculoskelet Disord. 2020 Jun 10;21(1):368. doi: 10.1186/s12891-020-03381-4.

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