Effects of Hydration Changes on Neuromuscular Function of Athletes (H2OAthletes)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.

ClinicalTrials.gov Identifier: NCT05380089

Recruitment Status : Recruiting

First Posted : May 18, 2022

Last Update Posted : July 27, 2023

See Contacts and Locations

View this study on the modernized ClinicalTrials.gov

Sponsor:

Information provided by (Responsible Party):

Faculdade de Motricidade Humana

No Study Results Posted on ClinicalTrials.gov for this Study

About Study Results Reporting on ClinicalTrials.gov

Recruitment Status :	Recruiting
Estimated Primary Completion Date :	October 31, 2024
Estimated Study Completion Date :	December 31, 2024

Publications:

Suchomel TJ, Nimphius S, Stone MH. The Importance of Muscular Strength in Athletic Performance. Sports Med. 2016 Oct;46(10):1419-49. doi: 10.1007/s40279-016-0486-0.

Judelson DA, Maresh CM, Anderson JM, Armstrong LE, Casa DJ, Kraemer WJ, Volek JS. Hydration and muscular performance: does fluid balance affect strength, power and high-intensity endurance? Sports Med. 2007;37(10):907-21. doi: 10.2165/00007256-200737100-00006.

Suchomel TJ, Nimphius S, Bellon CR, Stone MH. The Importance of Muscular Strength: Training Considerations. Sports Med. 2018 Apr;48(4):765-785. doi: 10.1007/s40279-018-0862-z.

Folland JP, Williams AG. The adaptations to strength training : morphological and neurological contributions to increased strength. Sports Med. 2007;37(2):145-68. doi: 10.2165/00007256-200737020-00004.

Casa DJ. Exercise in the heat. I. Fundamentals of thermal physiology, performance implications, and dehydration. J Athl Train. 1999 Jul;34(3):246-52.

Sjogaard G. Water and electrolyte fluxes during exercise and their relation to muscle fatigue. Acta Physiol Scand Suppl. 1986;556:129-36.

Barley OR, Chapman DW, Blazevich AJ, Abbiss CR. Acute Dehydration Impairs Endurance Without Modulating Neuromuscular Function. Front Physiol. 2018 Nov 2;9:1562. doi: 10.3389/fphys.2018.01562. eCollection 2018.

Ftaiti F, Grelot L, Coudreuse JM, Nicol C. Combined effect of heat stress, dehydration and exercise on neuromuscular function in humans. Eur J Appl Physiol. 2001 Jan-Feb;84(1-2):87-94. doi: 10.1007/s004210000339.

Evetovich TK, Boyd JC, Drake SM, Eschbach LC, Magal M, Soukup JT, Webster MJ, Whitehead MT, Weir JP. Effect of moderate dehydration on torque, electromyography, and mechanomyography. Muscle Nerve. 2002 Aug;26(2):225-31. doi: 10.1002/mus.10203.

Bigard AX, Sanchez H, Claveyrolas G, Martin S, Thimonier B, Arnaud MJ. Effects of dehydration and rehydration on EMG changes during fatiguing contractions. Med Sci Sports Exerc. 2001 Oct;33(10):1694-700. doi: 10.1097/00005768-200110000-00013.

Rodger A, Papies EK. "I don't just drink water for the sake of it": Understanding the influence of value, reward, self-identity and early life on water drinking behaviour. Food Quality and Preference. 2022;99:104576.

Cheuvront SN, Kenefick RW. Dehydration: physiology, assessment, and performance effects. Compr Physiol. 2014 Jan;4(1):257-85. doi: 10.1002/cphy.c130017.

Belval LN, Hosokawa Y, Casa DJ, Adams WM, Armstrong LE, Baker LB, Burke L, Cheuvront S, Chiampas G, Gonzalez-Alonso J, Huggins RA, Kavouras SA, Lee EC, McDermott BP, Miller K, Schlader Z, Sims S, Stearns RL, Troyanos C, Wingo J. Practical Hydration Solutions for Sports. Nutrients. 2019 Jul 9;11(7):1550. doi: 10.3390/nu11071550.

Periard JD, Racinais S, Sawka MN. Adaptations and mechanisms of human heat acclimation: Applications for competitive athletes and sports. Scand J Med Sci Sports. 2015 Jun;25 Suppl 1:20-38. doi: 10.1111/sms.12408.

Perrier E, Vergne S, Klein A, Poupin M, Rondeau P, Le Bellego L, Armstrong LE, Lang F, Stookey J, Tack I. Hydration biomarkers in free-living adults with different levels of habitual fluid consumption. Br J Nutr. 2013 May;109(9):1678-87. doi: 10.1017/S0007114512003601. Epub 2012 Aug 31.

Armstrong LE, Munoz CX, Armstrong EM. Distinguishing Low and High Water Consumers-A Paradigm of Disease Risk. Nutrients. 2020 Mar 23;12(3):858. doi: 10.3390/nu12030858.

Johnson EC, Munoz CX, Le Bellego L, Klein A, Casa DJ, Maresh CM, Armstrong LE. Markers of the hydration process during fluid volume modification in women with habitual high or low daily fluid intakes. Eur J Appl Physiol. 2015 May;115(5):1067-74. doi: 10.1007/s00421-014-3088-2. Epub 2015 Jan 7.

Johnson EC, Munoz CX, Jimenez L, Le Bellego L, Kupchak BR, Kraemer WJ, Casa DJ, Maresh CM, Armstrong LE. Hormonal and Thirst Modulated Maintenance of Fluid Balance in Young Women with Different Levels of Habitual Fluid Consumption. Nutrients. 2016 May 18;8(5):302. doi: 10.3390/nu8050302.

Leiper JB, Pitsiladis Y, Maughan RJ. Comparison of water turnover rates in men undertaking prolonged cycling exercise and sedentary men. Int J Sports Med. 2001 Apr;22(3):181-5. doi: 10.1055/s-2001-15912.

Pross N, Demazieres A, Girard N, Barnouin R, Metzger D, Klein A, Perrier E, Guelinckx I. Effects of changes in water intake on mood of high and low drinkers. PLoS One. 2014 Apr 11;9(4):e94754. doi: 10.1371/journal.pone.0094754. eCollection 2014.

American College of Sports Medicine; Sawka MN, Burke LM, Eichner ER, Maughan RJ, Montain SJ, Stachenfeld NS. American College of Sports Medicine position stand. Exercise and fluid replacement. Med Sci Sports Exerc. 2007 Feb;39(2):377-90. doi: 10.1249/mss.0b013e31802ca597.

EFSA Panel on Dietetic Products N, Allergies. Scientific Opinion on Dietary Reference Values for water. EFSA Journal. 2010;8(3):1459.

Nunes CL, Matias CN, Santos DA, Morgado JP, Monteiro CP, Sousa M, Minderico CS, Rocha PM, St-Onge MP, Sardinha LB, Silva AM. Characterization and Comparison of Nutritional Intake between Preparatory and Competitive Phase of Highly Trained Athletes. Medicina (Kaunas). 2018 May 30;54(3):41. doi: 10.3390/medicina54030041.

Pilis K, Stec K, Pilis A, Mroczek A, Michalski C, Pilis W. Body composition and nutrition of female athletes. Rocz Panstw Zakl Hig. 2019;70(3):243-251. doi: 10.32394/rpzh.2019.0074.

Nuccio RP, Barnes KA, Carter JM, Baker LB. Fluid Balance in Team Sport Athletes and the Effect of Hypohydration on Cognitive, Technical, and Physical Performance. Sports Med. 2017 Oct;47(10):1951-1982. doi: 10.1007/s40279-017-0738-7.

Arnaoutis G, Kavouras SA, Angelopoulou A, Skoulariki C, Bismpikou S, Mourtakos S, Sidossis LS. Fluid Balance During Training in Elite Young Athletes of Different Sports. J Strength Cond Res. 2015 Dec;29(12):3447-52. doi: 10.1519/JSC.0000000000000400.

Hall JE. Guyton and Hall textbook of medical physiology e-Book: Elsevier Health Sciences; 2015.

Silva AM, Fields DA, Heymsfield SB, Sardinha LB. Body composition and power changes in elite judo athletes. Int J Sports Med. 2010 Oct;31(10):737-41. doi: 10.1055/s-0030-1255115. Epub 2010 Jul 19.

Silva AM, Fields DA, Heymsfield SB, Sardinha LB. Relationship between changes in total-body water and fluid distribution with maximal forearm strength in elite judo athletes. J Strength Cond Res. 2011 Sep;25(9):2488-95. doi: 10.1519/JSC.0b013e3181fb3dfb.

Silva AM, Matias CN, Santos DA, Rocha PM, Minderico CS, Sardinha LB. Increases in intracellular water explain strength and power improvements over a season. Int J Sports Med. 2014 Dec;35(13):1101-5. doi: 10.1055/s-0034-1371839. Epub 2014 Jul 10.

Armstrong LE. Assessing hydration status: the elusive gold standard. J Am Coll Nutr. 2007 Oct;26(5 Suppl):575S-584S. doi: 10.1080/07315724.2007.10719661.

Armstrong LE, Maughan RJ, Senay LC, Shirreffs SM. Limitations to the use of plasma osmolality as a hydration biomarker. Am J Clin Nutr. 2013 Aug;98(2):503-4. doi: 10.3945/ajcn.113.065466. No abstract available.

Barley OR, Chapman DW, Abbiss CR. Reviewing the current methods of assessing hydration in athletes. J Int Soc Sports Nutr. 2020 Oct 30;17(1):52. doi: 10.1186/s12970-020-00381-6.

Kyle UG, Bosaeus I, De Lorenzo AD, Deurenberg P, Elia M, Gomez JM, Heitmann BL, Kent-Smith L, Melchior JC, Pirlich M, Scharfetter H, Schols AM, Pichard C; Composition of the ESPEN Working Group. Bioelectrical impedance analysis--part I: review of principles and methods. Clin Nutr. 2004 Oct;23(5):1226-43. doi: 10.1016/j.clnu.2004.06.004.

Hetherington-Rauth M, Leu CG, Judice PB, Correia IR, Magalhaes JP, Sardinha LB. Whole body and regional phase angle as indicators of muscular performance in athletes. Eur J Sport Sci. 2021 Dec;21(12):1684-1692. doi: 10.1080/17461391.2020.1858971. Epub 2021 Jan 18.

Raman A, Schoeller DA, Subar AF, Troiano RP, Schatzkin A, Harris T, Bauer D, Bingham SA, Everhart JE, Newman AB, Tylavsky FA. Water turnover in 458 American adults 40-79 yr of age. Am J Physiol Renal Physiol. 2004 Feb;286(2):F394-401. doi: 10.1152/ajprenal.00295.2003. Epub 2003 Nov 4.

Stegeman D, Hermens H. Standards for surface electromyography: The European project Surface EMG for non-invasive assessment of muscles (SENIAM). Enschede: Roessingh Research and Development. 2007:108-12.

Puga AM, Lopez-Oliva S, Trives C, Partearroyo T, Varela-Moreiras G. Effects of Drugs and Excipients on Hydration Status. Nutrients. 2019 Mar 20;11(3):669. doi: 10.3390/nu11030669.

To Top