Transcranial Alternating Current Stimulation (tACS) for the Recovery of Phonological Short-Term Memory in Patients With Aphasia After Stroke

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ClinicalTrials.gov Identifier: NCT06048159

Recruitment Status : Recruiting

First Posted : September 21, 2023

Last Update Posted : March 13, 2024

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Sponsor:

Information provided by (Responsible Party):

Priyanka Shah-Basak, PhD, Medical College of Wisconsin

No Study Results Posted on ClinicalTrials.gov for this Study

About Study Results Reporting on ClinicalTrials.gov

Recruitment Status :	Recruiting
Estimated Primary Completion Date :	January 2033
Estimated Study Completion Date :	January 2033

Publications:

Pedersen PM, Jorgensen HS, Nakayama H, Raaschou HO, Olsen TS. Aphasia in acute stroke: incidence, determinants, and recovery. Ann Neurol. 1995 Oct;38(4):659-66. doi: 10.1002/ana.410380416.

Engelter ST, Gostynski M, Papa S, Frei M, Born C, Ajdacic-Gross V, Gutzwiller F, Lyrer PA. Epidemiology of aphasia attributable to first ischemic stroke: incidence, severity, fluency, etiology, and thrombolysis. Stroke. 2006 Jun;37(6):1379-84. doi: 10.1161/01.STR.0000221815.64093.8c. Epub 2006 May 11.

Shah-Basak PP, Norise C, Garcia G, Torres J, Faseyitan O, Hamilton RH. Individualized treatment with transcranial direct current stimulation in patients with chronic non-fluent aphasia due to stroke. Front Hum Neurosci. 2015 Apr 21;9:201. doi: 10.3389/fnhum.2015.00201. eCollection 2015.

Shah-Basak PP, Wurzman R, Purcell JB, Gervits F, Hamilton R. Fields or flows? A comparative metaanalysis of transcranial magnetic and direct current stimulation to treat post-stroke aphasia. Restor Neurol Neurosci. 2016 May 2;34(4):537-58. doi: 10.3233/RNN-150616.

Boyle M. Semantic feature analysis treatment for anomia in two fluent aphasia syndromes. Am J Speech Lang Pathol. 2004 Aug;13(3):236-49. doi: 10.1044/1058-0360(2004/025).

Leonard, C., Rochon, E., & Laird, L. (2008). Treating naming impairments in aphasia: Findings from a phonological components analysis treatment. Aphasiology, 22, 923-947. https://doi.org/10.1080/02687030701831474

Paulesu E, Frith CD, Frackowiak RS. The neural correlates of the verbal component of working memory. Nature. 1993 Mar 25;362(6418):342-5. doi: 10.1038/362342a0.

Buchsbaum BR, Olsen RK, Koch P, Berman KF. Human dorsal and ventral auditory streams subserve rehearsal-based and echoic processes during verbal working memory. Neuron. 2005 Nov 23;48(4):687-97. doi: 10.1016/j.neuron.2005.09.029.

Buchsbaum BR, Baldo J, Okada K, Berman KF, Dronkers N, D'Esposito M, Hickok G. Conduction aphasia, sensory-motor integration, and phonological short-term memory - an aggregate analysis of lesion and fMRI data. Brain Lang. 2011 Dec;119(3):119-28. doi: 10.1016/j.bandl.2010.12.001. Epub 2011 Jan 21.

Antal A, Paulus W. Transcranial alternating current stimulation (tACS). Front Hum Neurosci. 2013 Jun 28;7:317. doi: 10.3389/fnhum.2013.00317. Print 2013.

Helfrich RF, Schneider TR, Rach S, Trautmann-Lengsfeld SA, Engel AK, Herrmann CS. Entrainment of brain oscillations by transcranial alternating current stimulation. Curr Biol. 2014 Feb 3;24(3):333-9. doi: 10.1016/j.cub.2013.12.041. Epub 2014 Jan 23.

Violante IR, Li LM, Carmichael DW, Lorenz R, Leech R, Hampshire A, Rothwell JC, Sharp DJ. Externally induced frontoparietal synchronization modulates network dynamics and enhances working memory performance. Elife. 2017 Mar 14;6:e22001. doi: 10.7554/eLife.22001.

Herrmann CS, Rach S, Neuling T, Struber D. Transcranial alternating current stimulation: a review of the underlying mechanisms and modulation of cognitive processes. Front Hum Neurosci. 2013 Jun 14;7:279. doi: 10.3389/fnhum.2013.00279. eCollection 2013.

Benson, D. F., & Ardila, A. (1996). Aphasia: A Clinical Perspective. Oxford University Press.

Code C, Petheram B. Delivering for aphasia. Int J Speech Lang Pathol. 2011 Feb;13(1):3-10. doi: 10.3109/17549507.2010.520090.

Brooks SK, Webster RK, Smith LE, Woodland L, Wessely S, Greenberg N, Rubin GJ. The psychological impact of quarantine and how to reduce it: rapid review of the evidence. Lancet. 2020 Mar 14;395(10227):912-920. doi: 10.1016/S0140-6736(20)30460-8. Epub 2020 Feb 26.

Pietrabissa G, Simpson SG. Psychological Consequences of Social Isolation During COVID-19 Outbreak. Front Psychol. 2020 Sep 9;11:2201. doi: 10.3389/fpsyg.2020.02201. eCollection 2020.

Pollock A, St George B, Fenton M, Firkins L. Top 10 research priorities relating to life after stroke--consensus from stroke survivors, caregivers, and health professionals. Int J Stroke. 2014 Apr;9(3):313-20. doi: 10.1111/j.1747-4949.2012.00942.x. Epub 2012 Dec 11.